The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on: May 06,2024

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on:May 06,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on: April 24,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on:April 24,2024

COVID-19: Biomarkers linked to severe forms of the disease

by University of MontrealColorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captu

Updated on: April 13,2024

COVID-19: Biomarkers linked to severe forms of the disease

by University of MontrealColorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captu

Updated on:April 13,2024

Researchers link gut microbiome to rheumatoid arthritis prognosis

by Susan Murphy,Mayo ClinicCredit: Pixabay/CC0 Public DomainA significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in thei

Updated on: June 01,2024

Researchers link gut microbiome to rheumatoid arthritis prognosis

by Susan Murphy,Mayo ClinicCredit: Pixabay/CC0 Public DomainA significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in thei

Updated on:June 01,2024

AD most commonly used term in literature for atopic dermatitis

(HealthDay)—Atopic dermatitis (AD) is most commonly referred to as AD in the literature, according to a review published online July 8 inAllergy.Robert Kantor, from the Northwestern University F

Updated on: April 08,2024

AD most commonly used term in literature for atopic dermatitis

(HealthDay)—Atopic dermatitis (AD) is most commonly referred to as AD in the literature, according to a review published online July 8 inAllergy.Robert Kantor, from the Northwestern University F

Updated on:April 08,2024

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on: April 08,2024

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on:April 08,2024

Examining inflammatory bowel disease after a stem cell transplant

byUniversity of BaselColon sections of the index patient in active IBDvs. clinical remission (under infliximab therapy) were stained by immune histology for CD5 (a pan T cell marker) and f

Updated on: March 27,2024

Examining inflammatory bowel disease after a stem cell transplant

byUniversity of BaselColon sections of the index patient in active IBDvs. clinical remission (under infliximab therapy) were stained by immune histology for CD5 (a pan T cell marker) and f

Updated on:March 27,2024

COVID-19, MIS-C and Kawasaki disease share same immune response

by University of California - San DiegoUC San Diego researchers summarize the similarities and differences between COVID-19, MIS-C and Kawasaki disease, three conditions unified by the same immun

Updated on: April 09,2024

COVID-19, MIS-C and Kawasaki disease share same immune response

by University of California - San DiegoUC San Diego researchers summarize the similarities and differences between COVID-19, MIS-C and Kawasaki disease, three conditions unified by the same immun

Updated on:April 09,2024

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

Updated on: April 24,2024

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

Updated on:April 24,2024

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on: June 15,2024

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on:June 15,2024

Online therapy aids the isolated, immunosuppressed in pandemic

by Noah Fromson,University of MichiganCredit: CC0 Public DomainPeople with a rare autoimmune disease, who likely experience more serious isolation during a global pandemic, saw their anxiety and

Updated on: March 24,2024

Online therapy aids the isolated, immunosuppressed in pandemic

by Noah Fromson,University of MichiganCredit: CC0 Public DomainPeople with a rare autoimmune disease, who likely experience more serious isolation during a global pandemic, saw their anxiety and

Updated on:March 24,2024

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Updated on: March 24,2024

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Updated on:March 24,2024