TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on: May 08,2024

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on:May 08,2024

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on: June 15,2024

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on:June 15,2024

COVID-19: Biomarkers linked to severe forms of the disease

by University of MontrealColorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captu

Updated on: April 13,2024

COVID-19: Biomarkers linked to severe forms of the disease

by University of MontrealColorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captu

Updated on:April 13,2024

Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

by Keele UniversityPercentage of patients with at least 1 Read/SNOMED code for RA who meet the diagnosis algorithm. Panel A = percentage of patients ever receiving an RA Read/SNOMED code that mee

Updated on: March 28,2024

Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

by Keele UniversityPercentage of patients with at least 1 Read/SNOMED code for RA who meet the diagnosis algorithm. Panel A = percentage of patients ever receiving an RA Read/SNOMED code that mee

Updated on:March 28,2024

Takayasu arteritis, ulcerative colitis co-occurrence rate high

(HealthDay)—Takayasu arteritis (TAK) has a high rate of co-occurrence and genetic overlap with ulcerative colitis (UC), according to a study published in the August issue ofArthritis & Rheum

Updated on: March 24,2024

Takayasu arteritis, ulcerative colitis co-occurrence rate high

(HealthDay)—Takayasu arteritis (TAK) has a high rate of co-occurrence and genetic overlap with ulcerative colitis (UC), according to a study published in the August issue ofArthritis & Rheum

Updated on:March 24,2024

Sensors for a 'smart' wound bandage may track healing, immune response

by Skolkovo Institute of Science and TechnologyCredit: CC0 Public DomainResearchers from Skoltech and the University of Texas at Austin have presented a proof of concept for a wearable sensor tha

Updated on: May 05,2024

Sensors for a 'smart' wound bandage may track healing, immune response

by Skolkovo Institute of Science and TechnologyCredit: CC0 Public DomainResearchers from Skoltech and the University of Texas at Austin have presented a proof of concept for a wearable sensor tha

Updated on:May 05,2024

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

Updated on: April 13,2024

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

Updated on:April 13,2024

Study reveals increase in the need for psychology referrals for children with food allergies

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainWith the rise in incidence of food allergies in children in the past decade, there has been a corresponding

Updated on: November 01,2024

Study reveals increase in the need for psychology referrals for children with food allergies

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainWith the rise in incidence of food allergies in children in the past decade, there has been a corresponding

Updated on:November 01,2024

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on: May 06,2024

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on:May 06,2024

Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on: May 08,2024

Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on:May 08,2024

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on: April 08,2024

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on:April 08,2024

Scientists create first mouse model with complete, functional human immune system

byUniversity of Texas Health Science Center at San AntonioLeft, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale b

Updated on: July 09,2024

Scientists create first mouse model with complete, functional human immune system

byUniversity of Texas Health Science Center at San AntonioLeft, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale b

Updated on:July 09,2024