ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on: April 08,2024 19

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on:April 08,2024 19

MyD88—villain of allergies and asthma

by Lydia Goff ,Duke UniversityFlorescence microscopy image of mouse dendritic cells with mRNA-loaded blood cells.Even if you don't have allergies yourself, I guarantee you can list at

Updated on: April 20,2024 12

MyD88—villain of allergies and asthma

by Lydia Goff ,Duke UniversityFlorescence microscopy image of mouse dendritic cells with mRNA-loaded blood cells.Even if you don't have allergies yourself, I guarantee you can list at

Updated on:April 20,2024 12

T cell response not critical for immune memory to SARS-CoV-2 or recovery from COVID-19

by American Society for MicrobiologyTransmission electron micrograph of SARS-CoV-2 virus particles isolated from a patient. Credit: NIAIDNew research conducted in monkeys reveals that T cells are

Updated on: May 08,2024 6

T cell response not critical for immune memory to SARS-CoV-2 or recovery from COVID-19

by American Society for MicrobiologyTransmission electron micrograph of SARS-CoV-2 virus particles isolated from a patient. Credit: NIAIDNew research conducted in monkeys reveals that T cells are

Updated on:May 08,2024 6

Evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

by Medical University of South CarolinaHIV-positive, ART-treated patients with high levels of autoantibodies also have increased levels of bacteria (Staphylococcus aureus) products in their blood

Updated on: April 16,2024 17

Evidence for link between 'leaky gut' and autoantibody production in HIV-positive patients

by Medical University of South CarolinaHIV-positive, ART-treated patients with high levels of autoantibodies also have increased levels of bacteria (Staphylococcus aureus) products in their blood

Updated on:April 16,2024 17

Can a DNA construction kit replace expensive antibody medication?

by KU LeuvenCredit: CC0 Public DomainResearchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach

Updated on: April 15,2024 16

Can a DNA construction kit replace expensive antibody medication?

by KU LeuvenCredit: CC0 Public DomainResearchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach

Updated on:April 15,2024 16

Protein eIF4A emerges as a potential Achilles' heel for triple-negative breast cancer

by Baylor College of MedicineGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI172503Improving treatments for triple-negative breast cancer (TNBC), a

Updated on: April 15,2024 18

Protein eIF4A emerges as a potential Achilles' heel for triple-negative breast cancer

by Baylor College of MedicineGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI172503Improving treatments for triple-negative breast cancer (TNBC), a

Updated on:April 15,2024 18

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on: May 23,2024 8

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on:May 23,2024 8

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024 13

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024 13

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024 4

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024 4

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on: June 26,2024 4

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on:June 26,2024 4

Some allergens that cause contact dermatitis are found in masks that prevent COVID-19

by American College of Allergy, Asthma, and ImmunologyCredit: Pixabay/CC0 Public DomainThroughout the course of the COVID-19 pandemic, those able to wear a face mask have been encouraged to do so

Updated on: April 24,2024 12

Some allergens that cause contact dermatitis are found in masks that prevent COVID-19

by American College of Allergy, Asthma, and ImmunologyCredit: Pixabay/CC0 Public DomainThroughout the course of the COVID-19 pandemic, those able to wear a face mask have been encouraged to do so

Updated on:April 24,2024 12

Early knee arthritis symptoms first felt when using stairs

by University of LeedsPeople who suffer from knee pain when using the stairs may be experiencing the early symptoms of osteoarthritis, according to a new University of Leeds study.The research, p

Updated on: March 28,2024 13

Early knee arthritis symptoms first felt when using stairs

by University of LeedsPeople who suffer from knee pain when using the stairs may be experiencing the early symptoms of osteoarthritis, according to a new University of Leeds study.The research, p

Updated on:March 28,2024 13