Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on: May 08,2024

Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on:May 08,2024

Recurrent wheezing in children linked to 'silent' viral infections

by Josh Barney,University of VirginiaNearly a quarter of children with recurrent wheezing suffer from lung infections that present no symptoms and should be treated with antiviral medications, U

Updated on: August 08,2024

Recurrent wheezing in children linked to 'silent' viral infections

by Josh Barney,University of VirginiaNearly a quarter of children with recurrent wheezing suffer from lung infections that present no symptoms and should be treated with antiviral medications, U

Updated on:August 08,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Updated on: April 08,2024

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Updated on:April 08,2024

NIH should create an Office of Autoimmune Disease Research, says new report

by National Academies of Sciences, Engineering, and MedicineCredit: Pixabay/CC0 Public DomainWhile the quantity and quality of research that the National Institutes of Health (NIH) conducts on autoimm

Updated on: May 05,2024

NIH should create an Office of Autoimmune Disease Research, says new report

by National Academies of Sciences, Engineering, and MedicineCredit: Pixabay/CC0 Public DomainWhile the quantity and quality of research that the National Institutes of Health (NIH) conducts on autoimm

Updated on:May 05,2024

New pathway in immune defense discovered: Interaction of monocytes and platelets decoded

by Inka Väth,University Hospital Bonn(from left) Dr. Ibrahim Hawwari, Prof. Bernardo Franklin and Lukas Roßnagel discover new intercellular communication mechanism in which blood platelets, so-c

Updated on: July 09,2024

New pathway in immune defense discovered: Interaction of monocytes and platelets decoded

by Inka Väth,University Hospital Bonn(from left) Dr. Ibrahim Hawwari, Prof. Bernardo Franklin and Lukas Roßnagel discover new intercellular communication mechanism in which blood platelets, so-c

Updated on:July 09,2024

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on: May 06,2024

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on:May 06,2024

New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on: August 08,2024

New safety checklist aims to prevent side effects in patients with arthritis

by Line Rønn,Aarhus UniversityOverview of contraindications and warnings from EMA SmPC and FDA PI for biologic and targeted synthetic disease modifying antirheumatic drugs based on MedDRA system

Updated on:August 08,2024

Does body mass index impact pain in individuals with hand osteoarthritis?

by WileyCredit: Unsplash/CC0 Public DomainIn a study inArthritis & Rheumatologyof people with hand osteoarthritis, higher body mass index was associated with greater pain severity

Updated on: June 15,2024

Does body mass index impact pain in individuals with hand osteoarthritis?

by WileyCredit: Unsplash/CC0 Public DomainIn a study inArthritis & Rheumatologyof people with hand osteoarthritis, higher body mass index was associated with greater pain severity

Updated on:June 15,2024

Could painkillers be hiding serious arthritis condition from doctors?

by Euan Wemyss,University of AberdeenCould anti-inflammatory drugs be masking serious arthritis condition, University of Aberdeen to explore. Credit: University of AberdeenThousands of patients

Updated on: March 24,2024

Could painkillers be hiding serious arthritis condition from doctors?

by Euan Wemyss,University of AberdeenCould anti-inflammatory drugs be masking serious arthritis condition, University of Aberdeen to explore. Credit: University of AberdeenThousands of patients

Updated on:March 24,2024

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainAnaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary fo

Updated on: November 01,2024

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainAnaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary fo

Updated on:November 01,2024

Study investigates rates of adverse events for common rheumatoid arthritis drug

by Brigham and Women's HospitalCredit: CC0 Public DomainMethotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is

Updated on: June 17,2024

Study investigates rates of adverse events for common rheumatoid arthritis drug

by Brigham and Women's HospitalCredit: CC0 Public DomainMethotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is

Updated on:June 17,2024