TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on: April 24,2024

TLK protein inhibition activates the innate immune system

by Institute for Research in Biomedicine - IRBCancer cells with TLK inhibition show replication intermediates (green) at chromosome ends (red). Credit: IRB BarcelonaTousled-like kinases (TLKs) are a p

Updated on:April 24,2024

Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

by Keele UniversityPercentage of patients with at least 1 Read/SNOMED code for RA who meet the diagnosis algorithm. Panel A = percentage of patients ever receiving an RA Read/SNOMED code that mee

Updated on: March 28,2024

Proportion of adults diagnosed with inflammatory arthritis in England has increased by more than 40%

by Keele UniversityPercentage of patients with at least 1 Read/SNOMED code for RA who meet the diagnosis algorithm. Panel A = percentage of patients ever receiving an RA Read/SNOMED code that mee

Updated on:March 28,2024

Researchers link gut microbiome to rheumatoid arthritis prognosis

by Susan Murphy,Mayo ClinicCredit: Pixabay/CC0 Public DomainA significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in thei

Updated on: June 01,2024

Researchers link gut microbiome to rheumatoid arthritis prognosis

by Susan Murphy,Mayo ClinicCredit: Pixabay/CC0 Public DomainA significant indicator of whether a patient with rheumatoid arthritis will improve over the course of disease may lie in part in thei

Updated on:June 01,2024

Online therapy aids the isolated, immunosuppressed in pandemic

by Noah Fromson,University of MichiganCredit: CC0 Public DomainPeople with a rare autoimmune disease, who likely experience more serious isolation during a global pandemic, saw their anxiety and

Updated on: March 24,2024

Online therapy aids the isolated, immunosuppressed in pandemic

by Noah Fromson,University of MichiganCredit: CC0 Public DomainPeople with a rare autoimmune disease, who likely experience more serious isolation during a global pandemic, saw their anxiety and

Updated on:March 24,2024

AD most commonly used term in literature for atopic dermatitis

(HealthDay)—Atopic dermatitis (AD) is most commonly referred to as AD in the literature, according to a review published online July 8 inAllergy.Robert Kantor, from the Northwestern University F

Updated on: April 08,2024

AD most commonly used term in literature for atopic dermatitis

(HealthDay)—Atopic dermatitis (AD) is most commonly referred to as AD in the literature, according to a review published online July 8 inAllergy.Robert Kantor, from the Northwestern University F

Updated on:April 08,2024

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on: April 08,2024

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Updated on:April 08,2024

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on: March 24,2024

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on:March 24,2024

Examining inflammatory bowel disease after a stem cell transplant

byUniversity of BaselColon sections of the index patient in active IBDvs. clinical remission (under infliximab therapy) were stained by immune histology for CD5 (a pan T cell marker) and f

Updated on: March 27,2024

Examining inflammatory bowel disease after a stem cell transplant

byUniversity of BaselColon sections of the index patient in active IBDvs. clinical remission (under infliximab therapy) were stained by immune histology for CD5 (a pan T cell marker) and f

Updated on:March 27,2024

Takayasu arteritis, ulcerative colitis co-occurrence rate high

(HealthDay)—Takayasu arteritis (TAK) has a high rate of co-occurrence and genetic overlap with ulcerative colitis (UC), according to a study published in the August issue ofArthritis & Rheum

Updated on: March 24,2024

Takayasu arteritis, ulcerative colitis co-occurrence rate high

(HealthDay)—Takayasu arteritis (TAK) has a high rate of co-occurrence and genetic overlap with ulcerative colitis (UC), according to a study published in the August issue ofArthritis & Rheum

Updated on:March 24,2024

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Updated on: March 24,2024

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Updated on:March 24,2024

Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on: May 08,2024

Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on:May 08,2024

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

Updated on: April 24,2024

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

Updated on:April 24,2024