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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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Survival improving after hip and knee replacement

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu
The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr
Some allergens that cause contact dermatitis are found in masks that prevent COVID-19

Some allergens that cause contact dermatitis are found in masks that prevent COVID-19

by American College of Allergy, Asthma, and ImmunologyCredit: Pixabay/CC0 Public DomainThroughout the course of the COVID-19 pandemic, those able to wear a face mask have been encouraged to do so

Some allergens that cause contact dermatitis are found in masks that prevent COVID-19

by American College of Allergy, Asthma, and ImmunologyCredit: Pixabay/CC0 Public DomainThroughout the course of the COVID-19 pandemic, those able to wear a face mask have been encouraged to do so
Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator
Mast cell levels may explain sex differences in osteoarthritis pain

Mast cell levels may explain sex differences in osteoarthritis pain

by Hospital for Special SurgeryCredit: Pixabay/CC0 Public DomainInvestigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have signific

Mast cell levels may explain sex differences in osteoarthritis pain

by Hospital for Special SurgeryCredit: Pixabay/CC0 Public DomainInvestigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have signific
Drug shows promise to treat diet-induced osteoarthritis

Drug shows promise to treat diet-induced osteoarthritis

by Queensland University of TechnologyCredit: CC0 Public DomainQUT scientists have found that a drug derived from omega-3 fatty acids can reduce osteoarthritis inflammation that's been caused

Drug shows promise to treat diet-induced osteoarthritis

by Queensland University of TechnologyCredit: CC0 Public DomainQUT scientists have found that a drug derived from omega-3 fatty acids can reduce osteoarthritis inflammation that's been caused
Knee pain not linked with activity levels in adults with knee osteoarthritis

Knee pain not linked with activity levels in adults with knee osteoarthritis

by WileyCredit: CC0 Public DomainKnee pain was not associated with daily walking levels in anArthritis Care & Researchstudy of individuals with mild-to-moderate, symptomatic knee

Knee pain not linked with activity levels in adults with knee osteoarthritis

by WileyCredit: CC0 Public DomainKnee pain was not associated with daily walking levels in anArthritis Care & Researchstudy of individuals with mild-to-moderate, symptomatic knee
Inflammatory link discovered between arthritis and heart valve disease

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d

Inflammatory link discovered between arthritis and heart valve disease

by Walter and Eliza Hall InstituteAustralian researchers have used models to identify a potential link between excess production of inflammatory proteins that cause rheumatoid arthritis and the d
m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati
A common metabolite may help treat autoimmune diseases

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to
How a COVID-19 infection spurs antibodies against common colds

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s
Researchers find new way to curb asthma attacks

Researchers find new way to curb asthma attacks

by Dennis ThompsonA protein that shuts down immune cells in the lungs could be key to a new treatment for asthma attacks, a new report says.The naturally occurringprotein, called Piezo1, prevent

Researchers find new way to curb asthma attacks

by Dennis ThompsonA protein that shuts down immune cells in the lungs could be key to a new treatment for asthma attacks, a new report says.The naturally occurringprotein, called Piezo1, prevent