Immunology & Rheumatology

Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on: May 08,2024

Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on:May 08,2024

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Updated on: June 15,2024

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Updated on:June 15,2024

New study reveals specialization of immune cells in different tissues

byKarolinska InstitutetJohan Sandberg. Credit: Karolinska InstitutetA new study from Karolinska Institutet has mapped how MAIT cells, which play an important role in the body's defense again

Updated on: September 18,2024

New study reveals specialization of immune cells in different tissues

byKarolinska InstitutetJohan Sandberg. Credit: Karolinska InstitutetA new study from Karolinska Institutet has mapped how MAIT cells, which play an important role in the body's defense again

Updated on:September 18,2024

Mood disorders common with rheumatoid arthritis

(HealthDay)—Depression and anxiety are common in patients with rheumatoid arthritis (RA), according to a study published online Jan. 6 in theInternational Journal of Rheumatic Diseases.Wanruchad

Updated on: July 02,2024

Mood disorders common with rheumatoid arthritis

(HealthDay)—Depression and anxiety are common in patients with rheumatoid arthritis (RA), according to a study published online Jan. 6 in theInternational Journal of Rheumatic Diseases.Wanruchad

Updated on:July 02,2024

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on: April 08,2024

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on:April 08,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on: May 08,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on:May 08,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on: April 17,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on:April 17,2024

Role of ECHO emphasized in management of rheumatic heart disease

by Elana GotkineIn a report from the American Society of Echocardiography, published in the Jan. 1 issue of theJournal of the American Society of Echocardiography, the authors emphasize the role

Updated on: June 17,2024

Role of ECHO emphasized in management of rheumatic heart disease

by Elana GotkineIn a report from the American Society of Echocardiography, published in the Jan. 1 issue of theJournal of the American Society of Echocardiography, the authors emphasize the role

Updated on:June 17,2024

How IL-6 allows the immune response to develop for a key cell, the T follicular helper

by Jeff Hansen,University of Alabama at BirminghamAndre Ballesteros-Tato. Credit: UABThe body's immune response fights against infectious disease, and it safeguards against future infections

Updated on: April 16,2024

How IL-6 allows the immune response to develop for a key cell, the T follicular helper

by Jeff Hansen,University of Alabama at BirminghamAndre Ballesteros-Tato. Credit: UABThe body's immune response fights against infectious disease, and it safeguards against future infections

Updated on:April 16,2024

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Updated on: May 29,2024

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Updated on:May 29,2024

Minority patients with rheumatic diseases have worse COVID-19 outcomes

by American College of RheumatologyCredit: CC0 Public DomainNew research at ACR Convergence, the American College of Rheumatology's annual meeting, reveals that people of color with rheumatic