A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on: April 17,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on:April 17,2024

Unusual type of antibody shows ultrapotent activity against Zika

by Weill Cornell Medical CollegeZika virus particles (red) shown in African green monkey kidney cells. Credit: NIAIDAn unusual type of antibody that even at miniscule levels neutralizes the Zika

Updated on: May 07,2024

Unusual type of antibody shows ultrapotent activity against Zika

by Weill Cornell Medical CollegeZika virus particles (red) shown in African green monkey kidney cells. Credit: NIAIDAn unusual type of antibody that even at miniscule levels neutralizes the Zika

Updated on:May 07,2024

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on: March 28,2024

Study aims to unravel the genetic causes of osteoarthritis

by Wellcome Trust Sanger InstituteA hip with osteoarthritis. In an X-ray of a healthy hip, the heads of the hip bone have smooth, evenly curved surfaces and there is a 'gap' between the h

Updated on:March 28,2024

Meta-analysis quantifies lifestyle factors accounting for RA incidence

(HealthDay)—Nearly one-third of rheumatoid arthritis (RA) incidence is attributed to smoking, excess body mass index, and low alcohol consumption, according to a study published online Jan. 26 in&nbsp

Updated on: May 08,2024

Meta-analysis quantifies lifestyle factors accounting for RA incidence

(HealthDay)—Nearly one-third of rheumatoid arthritis (RA) incidence is attributed to smoking, excess body mass index, and low alcohol consumption, according to a study published online Jan. 26 in&nbsp

Updated on:May 08,2024

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on: July 02,2024

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on:July 02,2024

FDA approves 1st drug for moderate and severe eczema cases

by Linda A. JohnsonThis image provided by Sanofi shows a box containing two single-dose pre-filled syringes of the drug Dupixent. On Tuesday, March 28, 2017, the Food and Drug Administration approved

Updated on: April 15,2024

FDA approves 1st drug for moderate and severe eczema cases

by Linda A. JohnsonThis image provided by Sanofi shows a box containing two single-dose pre-filled syringes of the drug Dupixent. On Tuesday, March 28, 2017, the Food and Drug Administration approved

Updated on:April 15,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

Knee pain not linked with activity levels in adults with knee osteoarthritis

by WileyCredit: CC0 Public DomainKnee pain was not associated with daily walking levels in anArthritis Care & Researchstudy of individuals with mild-to-moderate, symptomatic knee

Updated on: April 17,2024

Knee pain not linked with activity levels in adults with knee osteoarthritis

by WileyCredit: CC0 Public DomainKnee pain was not associated with daily walking levels in anArthritis Care & Researchstudy of individuals with mild-to-moderate, symptomatic knee

Updated on:April 17,2024

COVID infection may boost antibodies for up to 20 months

If you've already had COVID-19, your natural antibodies may last as long as 20 months, a new study suggests.While this is reassuring, experts are quick to caution that the new findings don't n

Updated on: April 13,2024

COVID infection may boost antibodies for up to 20 months

If you've already had COVID-19, your natural antibodies may last as long as 20 months, a new study suggests.While this is reassuring, experts are quick to caution that the new findings don't n

Updated on:April 13,2024

Fracture risk down with adherence to bisphosphonates

For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate

Updated on: March 24,2024

Fracture risk down with adherence to bisphosphonates

For patients with an osteoporotic fracture, adherence to bisphosphonate treatment is associated with reduced fracture risk; and for veterans with rheumatoid arthritis, non-adherence to bisphosphonate

Updated on:March 24,2024

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on: May 23,2024

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on:May 23,2024