Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on: September 07,2024 0

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on:September 07,2024 0

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis

Updated on: March 24,2024 19

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis

Updated on:March 24,2024 19

A protein that controls inflammation

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical

Updated on: April 20,2024 14

A protein that controls inflammation

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical

Updated on:April 20,2024 14

Immune receptor provides protective immunity against Group A Streptococcus

by Osaka UniversityFig. 1: The mechanism by which group A Streptococcus (GAS) evades the immune system. The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and t

Updated on: April 16,2024 19

Immune receptor provides protective immunity against Group A Streptococcus

by Osaka UniversityFig. 1: The mechanism by which group A Streptococcus (GAS) evades the immune system. The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and t

Updated on:April 16,2024 19

PFAS shown to reduce the activity of immune cells

by Helmholtz Association of German Research CentresGraphical abstract. Credit:Chemosphere(2023). DOI: 10.1016/j.chemosphere.2023.139204PFAS are used in many everyday products. This is

Updated on: April 20,2024 19

PFAS shown to reduce the activity of immune cells

by Helmholtz Association of German Research CentresGraphical abstract. Credit:Chemosphere(2023). DOI: 10.1016/j.chemosphere.2023.139204PFAS are used in many everyday products. This is

Updated on:April 20,2024 19

Minority patients with rheumatic diseases have worse COVID-19 outcomes

by American College of RheumatologyCredit: CC0 Public DomainNew research at ACR Convergence, the American College of Rheumatology's annual meeting, reveals that people of color with rheumatic

Updated on: May 29,2024 5

Minority patients with rheumatic diseases have worse COVID-19 outcomes

by American College of RheumatologyCredit: CC0 Public DomainNew research at ACR Convergence, the American College of Rheumatology's annual meeting, reveals that people of color with rheumatic

Updated on:May 29,2024 5

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on: April 16,2024 17

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on:April 16,2024 17

Study establishes IL-24 as a critical factor for onset and progression of atopic dermatitis

by Higher Education PressIL-24, which is expressed in keratinocytes and induced by S. aureus infection, promotes atopic dermatitis-like inflammation by enhancing a type 2 immune response. Credit: Xinm

Updated on: September 04,2024 0

Study establishes IL-24 as a critical factor for onset and progression of atopic dermatitis

by Higher Education PressIL-24, which is expressed in keratinocytes and induced by S. aureus infection, promotes atopic dermatitis-like inflammation by enhancing a type 2 immune response. Credit: Xinm

Updated on:September 04,2024 0

Does physical activity impact risk of knee osteoarthritis?

by WileyCredit: CC0 Public DomainIn an analysis published inArthritis & Rheumatology, investigators did not find any link between the amount and duration of physical activity with indiv

Updated on: April 17,2024 14

Does physical activity impact risk of knee osteoarthritis?

by WileyCredit: CC0 Public DomainIn an analysis published inArthritis & Rheumatology, investigators did not find any link between the amount and duration of physical activity with indiv

Updated on:April 17,2024 14

Lab-created molecule achieves positive results in the treatment of arthritis

by FAPESPArthritic mouse paw treated with TPPU (left) and untreated paw of another arthritic mouse. The substance decreased the area affected, reduced local swelling, and assuaged the pain associ

Updated on: March 24,2024 18

Lab-created molecule achieves positive results in the treatment of arthritis

by FAPESPArthritic mouse paw treated with TPPU (left) and untreated paw of another arthritic mouse. The substance decreased the area affected, reduced local swelling, and assuaged the pain associ

Updated on:March 24,2024 18

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on: July 09,2024 0

Small molecules induce trained immunity, opening a new approach to fighting disease

by Emily Ayshford,University of ChicagoMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteVaccines provide a front-lin

Updated on:July 09,2024 0

Study upends understanding about joint injuries

by Cornell UniversityCredit: CC0 Public DomainAn injury to the anterior cruciate ligament (ACL) can lead to severe osteoarthritis in both animal and human patients. Now, a new interdisciplinary s

Updated on: March 28,2024 20

Study upends understanding about joint injuries

by Cornell UniversityCredit: CC0 Public DomainAn injury to the anterior cruciate ligament (ACL) can lead to severe osteoarthritis in both animal and human patients. Now, a new interdisciplinary s

Updated on:March 28,2024 20