Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on: March 27,2024

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on:March 27,2024

Detecting arthritis with light

by Fraunhofer-GesellschaftA finger scanner allows doctors to detect arthritis in its early stages. Credit: Fraunhofer IBMT/Bernd MüllerJoint inflammation (arthritis) is a common problem in medica

Updated on: April 07,2024

Detecting arthritis with light

by Fraunhofer-GesellschaftA finger scanner allows doctors to detect arthritis in its early stages. Credit: Fraunhofer IBMT/Bernd MüllerJoint inflammation (arthritis) is a common problem in medica

Updated on:April 07,2024

Unusual type of antibody shows ultrapotent activity against Zika

by Weill Cornell Medical CollegeZika virus particles (red) shown in African green monkey kidney cells. Credit: NIAIDAn unusual type of antibody that even at miniscule levels neutralizes the Zika

Updated on: May 07,2024

Unusual type of antibody shows ultrapotent activity against Zika

by Weill Cornell Medical CollegeZika virus particles (red) shown in African green monkey kidney cells. Credit: NIAIDAn unusual type of antibody that even at miniscule levels neutralizes the Zika

Updated on:May 07,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on: April 10,2024

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on:April 10,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024

The 'greying' of T cells: Scientists pinpoint metabolic pathway behind age-related immunity loss

by Harvard Medical SchoolCredit: CC0 Public DomainThe elderly suffer more serious complications from infections and benefit less from vaccination than the general population. Scientists have long

Updated on: May 06,2024

The 'greying' of T cells: Scientists pinpoint metabolic pathway behind age-related immunity loss

by Harvard Medical SchoolCredit: CC0 Public DomainThe elderly suffer more serious complications from infections and benefit less from vaccination than the general population. Scientists have long

Updated on:May 06,2024

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on: May 23,2024

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on:May 23,2024

T cells: Vesicles strengthen immune response

by Ludwig Maximilian University of MunichMFG-E8-eGFP detects PS+ apoptotic and PS+ EV-decorated cells in vivo. Credit: Proceedings of the National Academy of Sciences (2023). DOI: 10.1073/pnas.22

Updated on: May 05,2024

T cells: Vesicles strengthen immune response

by Ludwig Maximilian University of MunichMFG-E8-eGFP detects PS+ apoptotic and PS+ EV-decorated cells in vivo. Credit: Proceedings of the National Academy of Sciences (2023). DOI: 10.1073/pnas.22

Updated on:May 05,2024

CRISPR screen reveals loss of genes in interferon gamma receptor signaling pathway

by Massachusetts General HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma recept

Updated on: April 13,2024

CRISPR screen reveals loss of genes in interferon gamma receptor signaling pathway

by Massachusetts General HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma recept

Updated on:April 13,2024

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis

Updated on: March 24,2024

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis

Updated on:March 24,2024

Could painkillers be hiding serious arthritis condition from doctors?

by Euan Wemyss,University of AberdeenCould anti-inflammatory drugs be masking serious arthritis condition, University of Aberdeen to explore. Credit: University of AberdeenThousands of patients

Updated on: March 24,2024

Could painkillers be hiding serious arthritis condition from doctors?

by Euan Wemyss,University of AberdeenCould anti-inflammatory drugs be masking serious arthritis condition, University of Aberdeen to explore. Credit: University of AberdeenThousands of patients

Updated on:March 24,2024

Old immune systems revitalized in mouse study, may improve vaccine response in the elderly

byStanford University Medical CenterCredit: CC0 Public DomainPlanes, trains, boats, automobiles and even feet. During the past decades and centuries, global travel and human migration have made

Updated on: March 30,2024

Old immune systems revitalized in mouse study, may improve vaccine response in the elderly

byStanford University Medical CenterCredit: CC0 Public DomainPlanes, trains, boats, automobiles and even feet. During the past decades and centuries, global travel and human migration have made

Updated on:March 30,2024