A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024

Rheumatoid arthritis tied to heavy economic and human burdens

by Lori SolomonRheumatoid arthritis (RA) is associated with higher health care expenditures and suboptimal quality of life in U.S. adults, according to a studypublishedonline Aug. 6 in&nbs

Updated on: October 09,2024

Rheumatoid arthritis tied to heavy economic and human burdens

by Lori SolomonRheumatoid arthritis (RA) is associated with higher health care expenditures and suboptimal quality of life in U.S. adults, according to a studypublishedonline Aug. 6 in&nbs

Updated on:October 09,2024

Study finds COVID-19 vaccine not associated with severe disease flare in patients with rheumatic diseases

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that the

Updated on: June 17,2024

Study finds COVID-19 vaccine not associated with severe disease flare in patients with rheumatic diseases

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that the

Updated on:June 17,2024

Protein eIF4A emerges as a potential Achilles' heel for triple-negative breast cancer

by Baylor College of MedicineGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI172503Improving treatments for triple-negative breast cancer (TNBC), a

Updated on: April 15,2024

Protein eIF4A emerges as a potential Achilles' heel for triple-negative breast cancer

by Baylor College of MedicineGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI172503Improving treatments for triple-negative breast cancer (TNBC), a

Updated on:April 15,2024

Chip identifies rhinoviruses as cause of asthma

by Medical University of ViennaCredit: Medical University of ViennaMedUni Vienna has developed a method that can be used to identify individual rhinovirus strains ("cold viruses") as a

Updated on: April 09,2024

Chip identifies rhinoviruses as cause of asthma

by Medical University of ViennaCredit: Medical University of ViennaMedUni Vienna has developed a method that can be used to identify individual rhinovirus strains ("cold viruses") as a

Updated on:April 09,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on: April 17,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on:April 17,2024

CRISPR screen reveals loss of genes in interferon gamma receptor signaling pathway

by Massachusetts General HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma recept

Updated on: April 13,2024

CRISPR screen reveals loss of genes in interferon gamma receptor signaling pathway

by Massachusetts General HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma recept

Updated on:April 13,2024

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on: May 29,2024

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on:May 29,2024

OX40-positive follicular helper T cells control rheumatoid arthritis

by University of TsukubaCredit: CC0 Public DomainRheumatoid arthritis is a progressive autoimmune disease most frequently characterized by pain, swelling, and stiffness in joints. Increased numbe

Updated on: June 17,2024

OX40-positive follicular helper T cells control rheumatoid arthritis

by University of TsukubaCredit: CC0 Public DomainRheumatoid arthritis is a progressive autoimmune disease most frequently characterized by pain, swelling, and stiffness in joints. Increased numbe

Updated on:June 17,2024

Scientists discover new mechanism controlling T-cells in inflammation

by Melissa Rohman,Northwestern UniversityGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.08.008Northwestern Medicine scientists have discovered a new mechanism

Updated on: October 10,2024

Scientists discover new mechanism controlling T-cells in inflammation

by Melissa Rohman,Northwestern UniversityGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.08.008Northwestern Medicine scientists have discovered a new mechanism

Updated on:October 10,2024

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on: May 23,2024

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on:May 23,2024

MRI-guided Tx strategy not superior for rheumatoid arthritis

(HealthDay)—A magnetic resonance imaging (MRI)-guided treat-to-target strategy is not associated with improved disease activity remission rates for patients with rheumatoid arthritis (RA) in clinical

Updated on: May 08,2024

MRI-guided Tx strategy not superior for rheumatoid arthritis

(HealthDay)—A magnetic resonance imaging (MRI)-guided treat-to-target strategy is not associated with improved disease activity remission rates for patients with rheumatoid arthritis (RA) in clinical

Updated on:May 08,2024