ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on: April 08,2024

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

by Osaka UniversityE-NTPD8 in colonic epithelial cells maintains gut homeostasis through the hydrolysis of luminal ATP produced by commensal bacteria (left). An increased level of luminal ATP cau

Updated on:April 08,2024

Chip identifies rhinoviruses as cause of asthma

by Medical University of ViennaCredit: Medical University of ViennaMedUni Vienna has developed a method that can be used to identify individual rhinovirus strains ("cold viruses") as a

Updated on: April 09,2024

Chip identifies rhinoviruses as cause of asthma

by Medical University of ViennaCredit: Medical University of ViennaMedUni Vienna has developed a method that can be used to identify individual rhinovirus strains ("cold viruses") as a

Updated on:April 09,2024

T-cells: The superheroes in the battle against omicron

by Luke O'neill,The ConversationCredit: AI-generated imageOmicron is spreading rapidly throughout the world, with experts claiming that 40% of the global population will be infected within t

Updated on: May 07,2024

T-cells: The superheroes in the battle against omicron

by Luke O'neill,The ConversationCredit: AI-generated imageOmicron is spreading rapidly throughout the world, with experts claiming that 40% of the global population will be infected within t

Updated on:May 07,2024

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on: May 29,2024

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on:May 29,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on: April 16,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on:April 16,2024

Arthritis, other chronic disease takes toll on work force

(HealthDay)—Among adults with one or more chronic conditions, those with arthritis appear much more likely than those without arthritis to have work disability, according to research published in the

Updated on: March 24,2024

Arthritis, other chronic disease takes toll on work force

(HealthDay)—Among adults with one or more chronic conditions, those with arthritis appear much more likely than those without arthritis to have work disability, according to research published in the

Updated on:March 24,2024

Researchers pursuing arthritis protein

by University of CopenhagenThe healthy blood cells stem from the blood bank at Rigshospitalet in Copenhagen, and more than 50 donors have been examined with the same result. Credit: Blood cells,

Updated on: March 24,2024

Researchers pursuing arthritis protein

by University of CopenhagenThe healthy blood cells stem from the blood bank at Rigshospitalet in Copenhagen, and more than 50 donors have been examined with the same result. Credit: Blood cells,

Updated on:March 24,2024

Redundancies in T cells

by Fabio Bergamin,ETH ZurichCredit: AI-generated imageResearchers at ETH Zurich have discovered redundancies in the biochemical signalling pathways of immune cells. This finding has important im

Updated on: May 05,2024

Redundancies in T cells

by Fabio Bergamin,ETH ZurichCredit: AI-generated imageResearchers at ETH Zurich have discovered redundancies in the biochemical signalling pathways of immune cells. This finding has important im

Updated on:May 05,2024

Serum biomarkers can differentiate psoriatic arthritis, rheumatoid arthritis

(HealthDay)—A serum protein biomarker panel can differentiate patients with early inflammatory arthritis with psoriatic arthritis (PsA) from those with rheumatoid arthritis (RA), according to a study

Updated on: June 06,2024

Serum biomarkers can differentiate psoriatic arthritis, rheumatoid arthritis

(HealthDay)—A serum protein biomarker panel can differentiate patients with early inflammatory arthritis with psoriatic arthritis (PsA) from those with rheumatoid arthritis (RA), according to a study

Updated on:June 06,2024

A stealthy way to combat tumors

by Anne Trafton,Massachusetts Institute of TechnologyMIT researchers have identified a specialized subset of dendritic cells that help stimulate T cells to attack tumors. In this image, the blue

Updated on: May 07,2024

A stealthy way to combat tumors

by Anne Trafton,Massachusetts Institute of TechnologyMIT researchers have identified a specialized subset of dendritic cells that help stimulate T cells to attack tumors. In this image, the blue

Updated on:May 07,2024

Investigators discover unique immune cells in patients with checkpoint inhibitor-induced arthritis

by Hospital for Special SurgeryCredit: CC0 Public DomainSince doctors began treating cancer patients with immunotherapy drugs called checkpoint inhibitors nearly a decade ago, they have observed

Updated on: June 17,2024

Investigators discover unique immune cells in patients with checkpoint inhibitor-induced arthritis

by Hospital for Special SurgeryCredit: CC0 Public DomainSince doctors began treating cancer patients with immunotherapy drugs called checkpoint inhibitors nearly a decade ago, they have observed

Updated on:June 17,2024