Study upends understanding about joint injuries

by Cornell UniversityCredit: CC0 Public DomainAn injury to the anterior cruciate ligament (ACL) can lead to severe osteoarthritis in both animal and human patients. Now, a new interdisciplinary s

Updated on: March 28,2024

Study upends understanding about joint injuries

by Cornell UniversityCredit: CC0 Public DomainAn injury to the anterior cruciate ligament (ACL) can lead to severe osteoarthritis in both animal and human patients. Now, a new interdisciplinary s

Updated on:March 28,2024

BAY 2927088 demonstrates 'rapid, substantial and durable responses' in patients with HER2-mutant NSCLC

BAY 2927088 demonstrates 'rapid, substantial and durable responses' in patients with HER2-mutant NSCLCby International Association for the Study of Lung CancerCredit: Unsplash/CC0 Public Domai

Updated on: September 25,2024

BAY 2927088 demonstrates 'rapid, substantial and durable responses' in patients with HER2-mutant NSCLC

BAY 2927088 demonstrates 'rapid, substantial and durable responses' in patients with HER2-mutant NSCLCby International Association for the Study of Lung CancerCredit: Unsplash/CC0 Public Domai

Updated on:September 25,2024

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis

Updated on: March 24,2024

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis

Updated on:March 24,2024

Serum biomarkers can differentiate psoriatic arthritis, rheumatoid arthritis

(HealthDay)—A serum protein biomarker panel can differentiate patients with early inflammatory arthritis with psoriatic arthritis (PsA) from those with rheumatoid arthritis (RA), according to a study

Updated on: June 06,2024

Serum biomarkers can differentiate psoriatic arthritis, rheumatoid arthritis

(HealthDay)—A serum protein biomarker panel can differentiate patients with early inflammatory arthritis with psoriatic arthritis (PsA) from those with rheumatoid arthritis (RA), according to a study

Updated on:June 06,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on: April 16,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on:April 16,2024

Chip identifies rhinoviruses as cause of asthma

by Medical University of ViennaCredit: Medical University of ViennaMedUni Vienna has developed a method that can be used to identify individual rhinovirus strains ("cold viruses") as a

Updated on: April 09,2024

Chip identifies rhinoviruses as cause of asthma

by Medical University of ViennaCredit: Medical University of ViennaMedUni Vienna has developed a method that can be used to identify individual rhinovirus strains ("cold viruses") as a

Updated on:April 09,2024

CRISPR screen reveals loss of genes in interferon gamma receptor signaling pathway

by Massachusetts General HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma recept

Updated on: April 13,2024

CRISPR screen reveals loss of genes in interferon gamma receptor signaling pathway

by Massachusetts General HospitalGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma recept

Updated on:April 13,2024

How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on: May 05,2024

How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on:May 05,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

Discovery may explain why more females than males get knee osteoarthritis

by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainFemale astronauts could avoid knee injuries during space flight—and better tests, prevention and treatments could be d

Updated on: March 28,2024

Discovery may explain why more females than males get knee osteoarthritis

by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainFemale astronauts could avoid knee injuries during space flight—and better tests, prevention and treatments could be d

Updated on:March 28,2024

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on: May 29,2024

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on:May 29,2024

T cells: Vesicles strengthen immune response

by Ludwig Maximilian University of MunichMFG-E8-eGFP detects PS+ apoptotic and PS+ EV-decorated cells in vivo. Credit: Proceedings of the National Academy of Sciences (2023). DOI: 10.1073/pnas.22

Updated on: May 05,2024

T cells: Vesicles strengthen immune response

by Ludwig Maximilian University of MunichMFG-E8-eGFP detects PS+ apoptotic and PS+ EV-decorated cells in vivo. Credit: Proceedings of the National Academy of Sciences (2023). DOI: 10.1073/pnas.22

Updated on:May 05,2024