Atopic dermatitis (AD) was associated with an increased risk for chronic kidney disease (CKD) in an Asian population, according to a study published online July 10 in the Journal of Dermatology.

Hsi-Chih Chen, from the Tri-Service General Hospital at the National Defense Medical Center in Taipei, Taiwan, and colleagues conducted a nationwide, longitudinal study to examine the correlation between AD and the risk for CKD using data from Taiwan's National Health Insurance Research Database. A total of 15, 179 individuals with AD were identified and compared to 60, 716 age- and sex-matched individuals without AD.

The researchers found that after adjustment for potential confounders, patients with AD had an elevated risk for CKD compared with the non-AD comparison cohort (adjusted odds ratio, 1.30). In both men and women and in all age groups, the association between AD and an increased risk for CKD was evident. There was a trend toward increasing odds ratios seen with increasing frequency of clinical visits for AD.

"Our findings remained robust in subgroup analyses, which demonstrate that a positive association exists between AD and CKD risk in both genders and in all age groups, " the authors write. "The clinical implications of the present study merit further investigation."

More information: Hsi‐Chih Chen et al, Increased Risk of Chronic Kidney Disease in Atopic Dermatitis: A Nationwide, Population‐Based Cohort Analysis, The Journal of Dermatology (2025). DOI: 10.1111/1346-8138.17841

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