CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

Updated on: May 30,2024 0

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

Updated on:May 30,2024 0

Ozempic mania's billions in bills are coming for US taxpayers

by Simone Foxman, Laura Nahmias, Bloomberg NewsCredit: Markus Winkler from PexelsState and local governments across the US are grappling with a growing problem: Expensive drugs to treat diabetes and o

Updated on: January 26,2024 19

Ozempic mania's billions in bills are coming for US taxpayers

by Simone Foxman, Laura Nahmias, Bloomberg NewsCredit: Markus Winkler from PexelsState and local governments across the US are grappling with a growing problem: Expensive drugs to treat diabetes and o

Updated on:January 26,2024 19

Patients with device-detected atrial fibrillation and multiple comorbidities do not benefit from anticoagulation: Study

by Angelika Leute, Kompetenznetz Vorhofflimmern e.V. (AFNET)Credit:European Heart Journal(2024). DOI: 10.1093/eurheartj/ehae225In patients with device-detected atrial fibrillation and a hi

Updated on: April 28,2024 0

Patients with device-detected atrial fibrillation and multiple comorbidities do not benefit from anticoagulation: Study

by Angelika Leute, Kompetenznetz Vorhofflimmern e.V. (AFNET)Credit:European Heart Journal(2024). DOI: 10.1093/eurheartj/ehae225In patients with device-detected atrial fibrillation and a hi

Updated on:April 28,2024 0

Siris tree leaves hold promise for stopping spread of breast cancer cells, say researchers

by University of SharjahAlbizia lebbeck—Shirish/Siris Tree. Credit: Wikimedia Commons,CC BY-SA 4.0Albizia lebbeck is the scientific name of the siris tree, which may hold the promise of wor

Updated on: April 06,2024 0

Siris tree leaves hold promise for stopping spread of breast cancer cells, say researchers

by University of SharjahAlbizia lebbeck—Shirish/Siris Tree. Credit: Wikimedia Commons,CC BY-SA 4.0Albizia lebbeck is the scientific name of the siris tree, which may hold the promise of wor

Updated on:April 06,2024 0

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Updated on: January 09,2024 10

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Updated on:January 09,2024 10

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Updated on: January 26,2024 12

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Updated on:January 26,2024 12

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley

Updated on: January 26,2024 18

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley

Updated on:January 26,2024 18

Mantle cell lymphoma patients see improved outcomes with oral combination of ibrutinib and venetoclax

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (

Updated on: January 26,2024 7

Mantle cell lymphoma patients see improved outcomes with oral combination of ibrutinib and venetoclax

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (

Updated on:January 26,2024 7

Innovators in HIV prevention and treatment, advocates for science and social justice

Updated on: October 21,2024 0

Innovators in HIV prevention and treatment, advocates for science and social justice

Updated on:October 21,2024 0

Mechanical engineers develop miniaturized, hydrogel-based electric generators for biomedical devices

by The University of Hong KongThe hydrogel electric generator and its working mechanism. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-45931-7Mechanoelectrical energy conversion offers

Updated on: May 14,2024 0

Mechanical engineers develop miniaturized, hydrogel-based electric generators for biomedical devices

by The University of Hong KongThe hydrogel electric generator and its working mechanism. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-45931-7Mechanoelectrical energy conversion offers

Updated on:May 14,2024 0

Evaluating selpercatinib for the treatment of non-small cell lung cancer

by D'Or Institute for Research and EducationCredit: Unsplash/CC0 Public DomainA phase III LIBRETTO-431 multicenter study has evaluated the efficacy and safety of selpercatinib compared to control

Updated on: January 26,2024 14

Evaluating selpercatinib for the treatment of non-small cell lung cancer

by D'Or Institute for Research and EducationCredit: Unsplash/CC0 Public DomainA phase III LIBRETTO-431 multicenter study has evaluated the efficacy and safety of selpercatinib compared to control

Updated on:January 26,2024 14

Bowel Habits and Brain Power: Unveiling the Hidden Connection

Updated on: July 15,2024 0

Bowel Habits and Brain Power: Unveiling the Hidden Connection

Updated on:July 15,2024 0