Scientists discover 'entirely unanticipated' role of protein netrin1 in spinal cord development

by Ani Vahradyan,University of California, Los AngelesCells (blue) at the ventral midline of the spinal cord, expressing netrin1 (red) and a fluorescent tracer (GFP, green). Credit: Samantha But

Updated on: November 22,2024 0

Scientists discover 'entirely unanticipated' role of protein netrin1 in spinal cord development

by Ani Vahradyan,University of California, Los AngelesCells (blue) at the ventral midline of the spinal cord, expressing netrin1 (red) and a fluorescent tracer (GFP, green). Credit: Samantha But

Updated on:November 22,2024 0

FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on: November 22,2024 0

FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on:November 22,2024 0

Study shows potential of optogenetics in treating epilepsy

byUniversity of California, San FranciscoHD-MEA recordings of human hippocampal slices. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01782-5In what could one day become

Updated on: November 22,2024 0

Study shows potential of optogenetics in treating epilepsy

byUniversity of California, San FranciscoHD-MEA recordings of human hippocampal slices. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01782-5In what could one day become

Updated on:November 22,2024 0

Scientists uncover new biallelic repeat expansion leading to mitochondrial encephalopathy

by Juntendo University Research Promotion CenterCredit:npj Genomic Medicine(2024). DOI: 10.1038/s41525-024-00429-5Mitochondrial diseases are among the most prevalent hereditary metabolic d

Updated on: November 22,2024 0

Scientists uncover new biallelic repeat expansion leading to mitochondrial encephalopathy

by Juntendo University Research Promotion CenterCredit:npj Genomic Medicine(2024). DOI: 10.1038/s41525-024-00429-5Mitochondrial diseases are among the most prevalent hereditary metabolic d

Updated on:November 22,2024 0

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on: November 22,2024 0

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on:November 22,2024 0

Huntington's disease gene may also enhance early brain development and intelligence

by Jennifer Brown,University of IowaYears-to-onset (YTO)-dependent brain functional changes. Credit:Annals of Neurology(2024). DOI: 10.1002/ana.27046The genetic mutation that causes

Updated on: November 22,2024 0

Huntington's disease gene may also enhance early brain development and intelligence

by Jennifer Brown,University of IowaYears-to-onset (YTO)-dependent brain functional changes. Credit:Annals of Neurology(2024). DOI: 10.1002/ana.27046The genetic mutation that causes

Updated on:November 22,2024 0

New therapeutic targets for Alzheimer's discovered in spinal fluid

Updated on: November 21,2024 0

New therapeutic targets for Alzheimer's discovered in spinal fluid

Updated on:November 21,2024 0

New research offers hope for treating inherited peripheral neuropathies

by Uniformed Services University of the Health Sciences (USU)Treating S63del mice for 21 days with tadalafil or CYR119 restores myelin thickness and nerve conduction in sciatic nerves. Credit:Ce

Updated on: November 14,2024 0

New research offers hope for treating inherited peripheral neuropathies

by Uniformed Services University of the Health Sciences (USU)Treating S63del mice for 21 days with tadalafil or CYR119 restores myelin thickness and nerve conduction in sciatic nerves. Credit:Ce

Updated on:November 14,2024 0

Immune exhaustion in myalgic encephalomyelitis/chronic fatigue syndrome and long COVID

byGriffith UniversityCredit: Griffith UniversityUnlocking the secrets behind immune exhaustion in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID patients is at the ce

Updated on: November 13,2024 0

Immune exhaustion in myalgic encephalomyelitis/chronic fatigue syndrome and long COVID

byGriffith UniversityCredit: Griffith UniversityUnlocking the secrets behind immune exhaustion in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID patients is at the ce

Updated on:November 13,2024 0

Researchers identify possible treatment for rare disorder CTNNB1 syndrome

byTufts UniversityCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-024-00110-5Researchers at Tufts University School of Medicine and the Graduate School of Biomedical Scienc

Updated on: November 12,2024 0

Researchers identify possible treatment for rare disorder CTNNB1 syndrome

byTufts UniversityCredit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-024-00110-5Researchers at Tufts University School of Medicine and the Graduate School of Biomedical Scienc

Updated on:November 12,2024 0

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on: November 12,2024 0

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on:November 12,2024 0

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024 0

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024 0