Use of MMR deficiency testing in younger CRC patients is low

(HealthDay)—Fewer than half of younger adults with colorectal cancer (CRC) undergo mismatch repair (MMR) deficiency of DNA testing, according to a study published online Nov. 9 inJAMA Oncology.T

Updated on: April 22,2024 14

Use of MMR deficiency testing in younger CRC patients is low

(HealthDay)—Fewer than half of younger adults with colorectal cancer (CRC) undergo mismatch repair (MMR) deficiency of DNA testing, according to a study published online Nov. 9 inJAMA Oncology.T

Updated on:April 22,2024 14

Potential overtreatment during life-limiting illness and end of life in older adults

by Gunilla Sonnebring,Karolinska InstitutetCredit: CC0 Public DomainA new thesis from Karolinska Institutet advocates end-of-life care that prioritizes the highest possible quality of life, avoi

Updated on: April 22,2024 13

Potential overtreatment during life-limiting illness and end of life in older adults

by Gunilla Sonnebring,Karolinska InstitutetCredit: CC0 Public DomainA new thesis from Karolinska Institutet advocates end-of-life care that prioritizes the highest possible quality of life, avoi

Updated on:April 22,2024 13

Even light alcohol consumption linked to higher cancer risk in Japan

by WileyCredit: CC0 Public DomainIn a study conducted in Japan, even light to moderate alcohol consumption was associated with elevated cancer risks. In the study published early online inC

Updated on: April 22,2024 10

Even light alcohol consumption linked to higher cancer risk in Japan

by WileyCredit: CC0 Public DomainIn a study conducted in Japan, even light to moderate alcohol consumption was associated with elevated cancer risks. In the study published early online inC

Updated on:April 22,2024 10

A common genetic signature has been discovered among three cancer prone rare skin diseases

by Carlos III University of MadridGene expression signature in fibroblasts from RDEB, KS and XPC patients, compared to healthy donors (a). An alteration common to the three diseases of 227 genes

Updated on: April 22,2024 18

A common genetic signature has been discovered among three cancer prone rare skin diseases

by Carlos III University of MadridGene expression signature in fibroblasts from RDEB, KS and XPC patients, compared to healthy donors (a). An alteration common to the three diseases of 227 genes

Updated on:April 22,2024 18

Growing microtumors in a dish helps rapidly identify genes that drive tumor growth

by Emily Stone,University of Illinois at ChicagoCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113355Researchers have identified a new way to screen genes that cause several d

Updated on: April 22,2024 13

Growing microtumors in a dish helps rapidly identify genes that drive tumor growth

by Emily Stone,University of Illinois at ChicagoCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113355Researchers have identified a new way to screen genes that cause several d

Updated on:April 22,2024 13

Growing brain cancer in a dish

by Austrian Academy of SciencesNeoplastic cerebral organoid with GFP-positive tumor regions (green), which demonstrates glioblastoma-like cellularity. Credit: Austrian Academy of SciencesFor the first

Updated on: April 22,2024 12

Growing brain cancer in a dish

by Austrian Academy of SciencesNeoplastic cerebral organoid with GFP-positive tumor regions (green), which demonstrates glioblastoma-like cellularity. Credit: Austrian Academy of SciencesFor the first

Updated on:April 22,2024 12

In the lab and in the clinic, alisertib with TAK-228 excels against solid tumors

by CU Anschutz Medical CampusUniversity of Colorado Cancer Center investigator, Jennifer Diamond, MD, and colleagues report promising phase I results of alisertib with TAK-228 against solid tumor

Updated on: April 22,2024 14

In the lab and in the clinic, alisertib with TAK-228 excels against solid tumors

by CU Anschutz Medical CampusUniversity of Colorado Cancer Center investigator, Jennifer Diamond, MD, and colleagues report promising phase I results of alisertib with TAK-228 against solid tumor

Updated on:April 22,2024 14

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

Updated on: April 22,2024 10

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

Updated on:April 22,2024 10

Doctors whose psychological needs are met associated with greater well-being in the new digital era

by American Academy of Family PhysiciansCredit: Pixabay/CC0 Public DomainCanadian researchers examined how the rapid shift to using virtual care during the COVID-19 pandemic has impacted primary

Updated on: April 22,2024 12

Doctors whose psychological needs are met associated with greater well-being in the new digital era

by American Academy of Family PhysiciansCredit: Pixabay/CC0 Public DomainCanadian researchers examined how the rapid shift to using virtual care during the COVID-19 pandemic has impacted primary

Updated on:April 22,2024 12

Alterations in the blood immune system found to increase cancer risk

by Germans Trias i Pujol Research InstitutePleiotropicRNYsare linked to SLE risk and plasmaRNYsare relatively abundant preceding breast cancer diagnosis.aScatter pl

Updated on: April 22,2024 0

Alterations in the blood immune system found to increase cancer risk

by Germans Trias i Pujol Research InstitutePleiotropicRNYsare linked to SLE risk and plasmaRNYsare relatively abundant preceding breast cancer diagnosis.aScatter pl

Updated on:April 22,2024 0

Major pathologic response to neoadjuvant pembrolizumab in advanced melanoma trial exceeds 50%

by SWOG Cancer Research NetworkCredit: CC0 Public DomainIn exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major patholog

Updated on: April 22,2024 20

Major pathologic response to neoadjuvant pembrolizumab in advanced melanoma trial exceeds 50%

by SWOG Cancer Research NetworkCredit: CC0 Public DomainIn exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major patholog

Updated on:April 22,2024 20

Few with CRC in sub-Saharan Africa receive guideline-concordant care

by Elana GotkineFewer than one in 20 patients diagnosed with colorectal cancer (CRC) in Sub-Saharan Africa (SSA) receive guideline-concordant treatment, according to a study published in the September

Updated on: April 22,2024 10

Few with CRC in sub-Saharan Africa receive guideline-concordant care

by Elana GotkineFewer than one in 20 patients diagnosed with colorectal cancer (CRC) in Sub-Saharan Africa (SSA) receive guideline-concordant treatment, according to a study published in the September

Updated on:April 22,2024 10