Destroying cancer-causing RNA could lead to bespoke treatments, say scientists

byPeter MacCallum Cancer CentreThe efficiency of PspCas13b silencing is highly variable between crRNAs. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-02

Updated on: July 05,2024

Destroying cancer-causing RNA could lead to bespoke treatments, say scientists

byPeter MacCallum Cancer CentreThe efficiency of PspCas13b silencing is highly variable between crRNAs. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-02

Updated on:July 05,2024

Researchers develop insights into KRAS mutations in pancreatic cancers

byWeill Cornell Medical CollegeSpatial molecular profiling of a resected pancreatic adenocarcinoma. Fluorescently-labeled probes bind to RNA targets to identify the location of different cell ty

Updated on: November 11,2024

Researchers develop insights into KRAS mutations in pancreatic cancers

byWeill Cornell Medical CollegeSpatial molecular profiling of a resected pancreatic adenocarcinoma. Fluorescently-labeled probes bind to RNA targets to identify the location of different cell ty

Updated on:November 11,2024

Researchers identify protein linked to heart failure in chemo patients

by University of ManitobaCredit: CC0 Public DomainA team led by Dr. Lorrie Kirshenbaum from the Rady Faculty of Health Sciences and St. Boniface Hospital Research has identified a protein called

Updated on: January 30,2024

Researchers identify protein linked to heart failure in chemo patients

by University of ManitobaCredit: CC0 Public DomainA team led by Dr. Lorrie Kirshenbaum from the Rady Faculty of Health Sciences and St. Boniface Hospital Research has identified a protein called

Updated on:January 30,2024

New approaches to personalized treatment for small cell lung cancer

by Johannes Angerer,Medical University of ViennaProteomic analysis of small-cell lung cancer (SCLC) cell lines highlights molecular heterogeneity: (A) The mRNA expression of key genes ASCL1, NEU

Updated on: January 11,2024

New approaches to personalized treatment for small cell lung cancer

by Johannes Angerer,Medical University of ViennaProteomic analysis of small-cell lung cancer (SCLC) cell lines highlights molecular heterogeneity: (A) The mRNA expression of key genes ASCL1, NEU

Updated on:January 11,2024

Novel T cell receptor therapy shows early anti-tumor activity

byUniversity of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainAfamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A

Updated on: January 15,2024

Novel T cell receptor therapy shows early anti-tumor activity

byUniversity of Texas M. D. Anderson Cancer CenterCredit: CC0 Public DomainAfamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A

Updated on:January 15,2024

New insight into combating drug-resistant prostate cancer

byUniversity of Eastern FinlandCredit:Nucleic Acids Research(2023). DOI: 10.1093/nar/gkad1126Recent research from the University of Eastern Finland sheds light on the significance of

Updated on: April 28,2024

New insight into combating drug-resistant prostate cancer

byUniversity of Eastern FinlandCredit:Nucleic Acids Research(2023). DOI: 10.1093/nar/gkad1126Recent research from the University of Eastern Finland sheds light on the significance of

Updated on:April 28,2024

Researchers demonstrate RAS dimers are essential for cancer

by Cathy Frisinger,UT Southwestern Medical CenterRAS oncogenes work in pairs, known as "dimers." Credit: UT SouthwesternMutated RAS genes are some of the most common genetic drivers of

Updated on: June 01,2024

Researchers demonstrate RAS dimers are essential for cancer

by Cathy Frisinger,UT Southwestern Medical CenterRAS oncogenes work in pairs, known as "dimers." Credit: UT SouthwesternMutated RAS genes are some of the most common genetic drivers of

Updated on:June 01,2024

Turncoat T cells: When exhausted, cancer-fighting T cells may switch sides

byUniversity of PittsburghGreg Delgoffe, Ph.D., associate professor of immunology at Pitt’s School of Medicine and director of the Tumor Microenvironment Center at UPMC Hillman Cancer Center. Cr

Updated on: January 02,2024

Turncoat T cells: When exhausted, cancer-fighting T cells may switch sides

byUniversity of PittsburghGreg Delgoffe, Ph.D., associate professor of immunology at Pitt’s School of Medicine and director of the Tumor Microenvironment Center at UPMC Hillman Cancer Center. Cr

Updated on:January 02,2024

New study shows Black cancer survivors face increased mortality from heart disease

byAmerican Cancer SocietyCredit: American Cancer SocietyA new study from researchers at the American Cancer Society (ACS) found that Black cancer survivors in the United States experience a high

Updated on: January 12,2024

New study shows Black cancer survivors face increased mortality from heart disease

byAmerican Cancer SocietyCredit: American Cancer SocietyA new study from researchers at the American Cancer Society (ACS) found that Black cancer survivors in the United States experience a high

Updated on:January 12,2024

Improving immune checkpoint inhibitors' anti-tumor response and minimizing side effects

byTohoku UniversityMetastatic lymph node targeted immune checkpoint blockade (ICB) elicits strong therapeutic response and ameliorates ICB-induced interstitial pneumonia. Credit: Tohoku Universi

Updated on: January 07,2024

Improving immune checkpoint inhibitors' anti-tumor response and minimizing side effects

byTohoku UniversityMetastatic lymph node targeted immune checkpoint blockade (ICB) elicits strong therapeutic response and ameliorates ICB-induced interstitial pneumonia. Credit: Tohoku Universi

Updated on:January 07,2024

Beating by overheating: A new strategy to combat cancer

byNetherlands Cancer InstituteOne could compare cancer cells subjected to the paradoxial approach in this study to the engine of a racing car: if you crank up the RPM and then turn off the cooli

Updated on: March 30,2024

Beating by overheating: A new strategy to combat cancer

byNetherlands Cancer InstituteOne could compare cancer cells subjected to the paradoxial approach in this study to the engine of a racing car: if you crank up the RPM and then turn off the cooli

Updated on:March 30,2024

Researchers discover how to steer army of immune cells toward cancer

by University of Rochester Medical CenterhHER2 CAR-T cell assays and in vivo distribution. a. Gating strategy for detection of hHER2-CAR-T cells. A median of > 90% of mouse CD8 T cells transdu

Updated on: February 01,2024

Researchers discover how to steer army of immune cells toward cancer

by University of Rochester Medical CenterhHER2 CAR-T cell assays and in vivo distribution. a. Gating strategy for detection of hHER2-CAR-T cells. A median of > 90% of mouse CD8 T cells transdu

Updated on:February 01,2024