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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part
Researchers convert pro-tumor macrophages into cancer killers

Researchers convert pro-tumor macrophages into cancer killers

by University of California - San DiegoCredit: CC0 Public DomainEpithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer ther

Researchers convert pro-tumor macrophages into cancer killers

by University of California - San DiegoCredit: CC0 Public DomainEpithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer ther
Oncolytic virus treatment produces promising results in patients with triple-negative breast cancer

Oncolytic virus treatment produces promising results in patients with triple-negative breast cancer

byH. Lee Moffitt Cancer Center & Research InstituteCredit: Unsplash/CC0 Public DomainTriple-negative breast cancer accounts for approximately 15% of all breast cancer cases. Patients with th

Oncolytic virus treatment produces promising results in patients with triple-negative breast cancer

byH. Lee Moffitt Cancer Center & Research InstituteCredit: Unsplash/CC0 Public DomainTriple-negative breast cancer accounts for approximately 15% of all breast cancer cases. Patients with th
Treatment beneficial for nonagenarians with lung cancer

Treatment beneficial for nonagenarians with lung cancer

(HealthDay)—Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a st

Treatment beneficial for nonagenarians with lung cancer

(HealthDay)—Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a st
Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo
Study uncovers how B cells react to skin cancer

Study uncovers how B cells react to skin cancer

by King's College LondonSpatial transcriptomic coupled with high throughput intratumoral antibody repertoire analyses suggest an active but aberrant B cell response.aRepresentativ

Study uncovers how B cells react to skin cancer

by King's College LondonSpatial transcriptomic coupled with high throughput intratumoral antibody repertoire analyses suggest an active but aberrant B cell response.aRepresentativ
Researchers find effective drug combinations for glioblastoma in mice

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea
Vitamin D deficiency in melanoma patients associated with worse overall survival, new study finds

Vitamin D deficiency in melanoma patients associated with worse overall survival, new study finds

by European Academy of Dermatology and VenereologyCredit: CC0 Public DomainVitamin D levels affect overall survival for melanoma (skin cancer) patients, a new study presented at the 31stEuropean

Vitamin D deficiency in melanoma patients associated with worse overall survival, new study finds

by European Academy of Dermatology and VenereologyCredit: CC0 Public DomainVitamin D levels affect overall survival for melanoma (skin cancer) patients, a new study presented at the 31stEuropean
Types of bacteria vary widely in tumors of people with early vs. late-onset colorectal cancer

Types of bacteria vary widely in tumors of people with early vs. late-onset colorectal cancer

by Georgetown University Medical CenterCredit: Pixabay/CC0 Public DomainResearchers at Georgetown University's Lombardi Comprehensive Cancer Center studied the microbiome of people with color

Types of bacteria vary widely in tumors of people with early vs. late-onset colorectal cancer

by Georgetown University Medical CenterCredit: Pixabay/CC0 Public DomainResearchers at Georgetown University's Lombardi Comprehensive Cancer Center studied the microbiome of people with color
New regulator in aggressive breast cancer cells discovered

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is
Origins of glioma brain cancer found to be in the epigenome

Origins of glioma brain cancer found to be in the epigenome

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainWhile cancers often originate from mutations and other alterations of cells' DNA, researchers in the Bernstein Laboratory at D

Origins of glioma brain cancer found to be in the epigenome

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainWhile cancers often originate from mutations and other alterations of cells' DNA, researchers in the Bernstein Laboratory at D
Study identifies new gene that drives colon cancer

Study identifies new gene that drives colon cancer

by The Mount Sinai HospitalRecurrently dysregulated super-enhancers in CRC patients.aStudy overview. Figure adapted from SMART Servier Medical Art, reproduced with permission, license

Study identifies new gene that drives colon cancer

by The Mount Sinai HospitalRecurrently dysregulated super-enhancers in CRC patients.aStudy overview. Figure adapted from SMART Servier Medical Art, reproduced with permission, license