Patients coping with mesothelioma experienced higher levels of toxicity on CheckMate743 regimen than reported in trials

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainBased on results from the CheckMate743 trial, the dual regimen of ipilimumab and nivolumab is the standard of

Updated on: April 10,2024

Patients coping with mesothelioma experienced higher levels of toxicity on CheckMate743 regimen than reported in trials

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainBased on results from the CheckMate743 trial, the dual regimen of ipilimumab and nivolumab is the standard of

Updated on:April 10,2024

Metastasizing cancer cells modify bone remodeling with small RNA secretion

by Tokyo Medical and Dental UniversityIn the bone metastatic microenvironment, the crosstalk between metastasized cancer cells and the surrounding bone cells is critical for the formation of the osteo

Updated on: April 01,2024

Metastasizing cancer cells modify bone remodeling with small RNA secretion

by Tokyo Medical and Dental UniversityIn the bone metastatic microenvironment, the crosstalk between metastasized cancer cells and the surrounding bone cells is critical for the formation of the osteo

Updated on:April 01,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on: June 04,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on:June 04,2024

Researchers discover new genetic link to premenopausal breast cancer

by University of Alberta Faculty of Medicine & DentistryGraduate student Mahalakshmi Kumaran (left) and professor Sambasivarao Damaraju led a team that discovered a new genetic marker linked

Updated on: June 22,2024

Researchers discover new genetic link to premenopausal breast cancer

by University of Alberta Faculty of Medicine & DentistryGraduate student Mahalakshmi Kumaran (left) and professor Sambasivarao Damaraju led a team that discovered a new genetic marker linked

Updated on:June 22,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on: April 07,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on:April 07,2024

Research could lead to better understanding of pancreatic cancer

by University of SurreyAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainSurrey's BioProChem group has developed a biomaterial based c

Updated on: June 28,2024

Research could lead to better understanding of pancreatic cancer

by University of SurreyAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainSurrey's BioProChem group has developed a biomaterial based c

Updated on:June 28,2024

Deep learning and radiomics allow precise differentiation in brain tumors

by Karl Landsteiner University of Health SciencesGeneral diagram of the proposed radiomics and radiophysiomics approach, showing the major steps: MRI data acquisition, calculation of MRI biomarker map

Updated on: January 04,2024

Deep learning and radiomics allow precise differentiation in brain tumors

by Karl Landsteiner University of Health SciencesGeneral diagram of the proposed radiomics and radiophysiomics approach, showing the major steps: MRI data acquisition, calculation of MRI biomarker map

Updated on:January 04,2024

New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

by Impact Journals LLCMDSCs generated by obesity migrate to lymphoid organ and TME. Credit: 2022 Shibata et al.A new review titled "Myeloid-derived suppressor cells: Cancer, autoimmune diseases,

Updated on: January 12,2024

New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

by Impact Journals LLCMDSCs generated by obesity migrate to lymphoid organ and TME. Credit: 2022 Shibata et al.A new review titled "Myeloid-derived suppressor cells: Cancer, autoimmune diseases,

Updated on:January 12,2024

Polybrominated diphenyl ether linked to increased risk for cancer mortality

by Elana GotkinePolybrominated diphenyl ether (PBDE) exposure is associated with an increased risk for cancer mortality, according to a studypublishedinJAMA Network Open.Buyun Liu, M

Updated on: April 06,2024

Polybrominated diphenyl ether linked to increased risk for cancer mortality

by Elana GotkinePolybrominated diphenyl ether (PBDE) exposure is associated with an increased risk for cancer mortality, according to a studypublishedinJAMA Network Open.Buyun Liu, M

Updated on:April 06,2024

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

Updated on: April 22,2024

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

Updated on:April 22,2024

In breast-cancer prevention, race matters

by The Ohio State UniversityCredit: CC0 Public DomainAfrican-American women at high risk of breast cancer are less likely than white women to pursue potentially life-saving preventive care, and r

Updated on: April 22,2024

In breast-cancer prevention, race matters

by The Ohio State UniversityCredit: CC0 Public DomainAfrican-American women at high risk of breast cancer are less likely than white women to pursue potentially life-saving preventive care, and r

Updated on:April 22,2024

Researchers discover connection between stress-activated signaling and immune cell evasion in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.08.016Anti-cancer immune cells are critical to inhibiti

Updated on: February 18,2024

Researchers discover connection between stress-activated signaling and immune cell evasion in melanoma

by H. Lee Moffitt Cancer Center & Research InstituteGraphical abstract. Credit:Cancer Cell(2022). DOI: 10.1016/j.ccell.2022.08.016Anti-cancer immune cells are critical to inhibiti

Updated on:February 18,2024