Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on: July 02,2024

Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on:July 02,2024

Gray hair and wrinkles at an early age lead researchers to potential new treatment for rare cancer

by University of CopenhagenSchematic representation of the PandaOmics application for a rapid biomarker discovery and target characterization in cancer. Gene expression signatures have been exami

Updated on: February 18,2024

Gray hair and wrinkles at an early age lead researchers to potential new treatment for rare cancer

by University of CopenhagenSchematic representation of the PandaOmics application for a rapid biomarker discovery and target characterization in cancer. Gene expression signatures have been exami

Updated on:February 18,2024

Researchers map genetic signature of precursor to liver cancer

by Curtin UniversityProfessor Nina Tirnitz-Parker and Dr. Rodrigo Carlessi, from Curtin University. Credit: Curtin UniversityResearchers at Curtin University have identified the genetic signature

Updated on: February 24,2024

Researchers map genetic signature of precursor to liver cancer

by Curtin UniversityProfessor Nina Tirnitz-Parker and Dr. Rodrigo Carlessi, from Curtin University. Credit: Curtin UniversityResearchers at Curtin University have identified the genetic signature

Updated on:February 24,2024

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on: January 12,2024

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on:January 12,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on: June 15,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on:June 15,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on: June 06,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on:June 06,2024

Researchers find epigenetic loss that changes how cells obtain energy from cancer

by University of BarcelonaThe researchers Margalida Rosselló-Tortella, Manel Esteller and Pere Llinàs-Arias. Credit: UNIVERSITY OF BARCELONAIt has been known for decades that cancer cells have an

Updated on: June 24,2024

Researchers find epigenetic loss that changes how cells obtain energy from cancer

by University of BarcelonaThe researchers Margalida Rosselló-Tortella, Manel Esteller and Pere Llinàs-Arias. Credit: UNIVERSITY OF BARCELONAIt has been known for decades that cancer cells have an

Updated on:June 24,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on: June 04,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on:June 04,2024

Researchers use machine learning to unlock the genomic code in clinical cancer samples

by University of HelsinkiMutational signatures of formalin exposure. a C>T FFPE-only mutation count increases with formalin fixation time. We observed this increase in both unrepaired and repa

Updated on: February 18,2024

Researchers use machine learning to unlock the genomic code in clinical cancer samples

by University of HelsinkiMutational signatures of formalin exposure. a C>T FFPE-only mutation count increases with formalin fixation time. We observed this increase in both unrepaired and repa

Updated on:February 18,2024

A code for reprogramming immune sentinels

by Lund UniversityArtistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Credit: National Institutes of Health (NI

Updated on: May 23,2024

A code for reprogramming immune sentinels

by Lund UniversityArtistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Credit: National Institutes of Health (NI

Updated on:May 23,2024

'Positive' trial for Pfizer-BioNTech COVID-flu jab

Credit: Unsplash/CC0 Public DomainGermany's BioNTech and US pharmaceutical giant Pfizer on Thursday announced "positive" results from initial trials of their combined mRNA vaccine agains

Updated on: March 01,2024

'Positive' trial for Pfizer-BioNTech COVID-flu jab

Credit: Unsplash/CC0 Public DomainGermany's BioNTech and US pharmaceutical giant Pfizer on Thursday announced "positive" results from initial trials of their combined mRNA vaccine agains

Updated on:March 01,2024

Researchers uncover potential biomarkers of positive response to immunotherapy

by Denise Heady,University of California, Los AngelesResponse to ICI or MAPKi therapy is associated with increased T cell infiltration and enhanced interferon gamma (IFNγ) pathway activity in th

Updated on: January 30,2024

Researchers uncover potential biomarkers of positive response to immunotherapy

by Denise Heady,University of California, Los AngelesResponse to ICI or MAPKi therapy is associated with increased T cell infiltration and enhanced interferon gamma (IFNγ) pathway activity in th

Updated on:January 30,2024