Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on: January 30,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on:January 30,2024

Researchers show that using a tumor's own bacteria is a promising anticancer therapy

by Japan Advanced Institute of Science and TechnologyA bacterial consortium consisting of A-gyo, UN-gyo, and AUN has high anticancer efficacy, triggering the immune system to attack tumor cells. Credi

Updated on: February 24,2024

Researchers show that using a tumor's own bacteria is a promising anticancer therapy

by Japan Advanced Institute of Science and TechnologyA bacterial consortium consisting of A-gyo, UN-gyo, and AUN has high anticancer efficacy, triggering the immune system to attack tumor cells. Credi

Updated on:February 24,2024

New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

by Impact Journals LLCMDSCs generated by obesity migrate to lymphoid organ and TME. Credit: 2022 Shibata et al.A new review titled "Myeloid-derived suppressor cells: Cancer, autoimmune diseases,

Updated on: January 12,2024

New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

by Impact Journals LLCMDSCs generated by obesity migrate to lymphoid organ and TME. Credit: 2022 Shibata et al.A new review titled "Myeloid-derived suppressor cells: Cancer, autoimmune diseases,

Updated on:January 12,2024

Researchers image live drug response and resistant 'pockets' in pancreatic cancer

by Garvan Institute of Medical ResearchSchematic of spatiotemporal AKT activity mapping in several organ systems in vivo.Optical window–mediated intravital assessment of metabolic and malignancy-

Updated on: February 18,2024

Researchers image live drug response and resistant 'pockets' in pancreatic cancer

by Garvan Institute of Medical ResearchSchematic of spatiotemporal AKT activity mapping in several organ systems in vivo.Optical window–mediated intravital assessment of metabolic and malignancy-

Updated on:February 18,2024

Researcher discusses how lung macrophages evolve during metastatic growth of lung colonies in a mouse model of melanoma

by Impact Journals LLCCredit: Unsplash/CC0 Public DomainA new editorial paper titled "A macrophage is a macrophage is a macrophage—in metastasis" has been published inOncotarget.In thi

Updated on: February 18,2024

Researcher discusses how lung macrophages evolve during metastatic growth of lung colonies in a mouse model of melanoma

by Impact Journals LLCCredit: Unsplash/CC0 Public DomainA new editorial paper titled "A macrophage is a macrophage is a macrophage—in metastasis" has been published inOncotarget.In thi

Updated on:February 18,2024

Researchers report on inhibitory effect of glioblastoma signals to macrophages

by University of BaselGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0"Don't eat me," is how one might translate the signal that the cancer cells in a glioblastoma sen

Updated on: February 18,2024

Researchers report on inhibitory effect of glioblastoma signals to macrophages

by University of BaselGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0"Don't eat me," is how one might translate the signal that the cancer cells in a glioblastoma sen

Updated on:February 18,2024

Researchers find a 'critical need' for whole genome sequencing of young cancer patients

by St. Jude Children's Research HospitalSt. Jude investigators (from left) Michael Rusch, Sheila Shurtleff, Ph.D., Jinghui Zhang, Ph.D., and Scott Newman, Ph.D. Credit: St. Jude Children'

Updated on: June 22,2024

Researchers find a 'critical need' for whole genome sequencing of young cancer patients

by St. Jude Children's Research HospitalSt. Jude investigators (from left) Michael Rusch, Sheila Shurtleff, Ph.D., Jinghui Zhang, Ph.D., and Scott Newman, Ph.D. Credit: St. Jude Children'

Updated on:June 22,2024

Multigene testing replacing BRCA tests for breast cancer risk, researcher says

by Stanford University Medical CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014

Updated on: June 24,2024

Multigene testing replacing BRCA tests for breast cancer risk, researcher says

by Stanford University Medical CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014

Updated on:June 24,2024

Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy

by Walter and Eliza Hall Institute of Medical ResearchGeneration and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral co

Updated on: February 03,2024

Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy

by Walter and Eliza Hall Institute of Medical ResearchGeneration and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral co

Updated on:February 03,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on: June 04,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on:June 04,2024

Researchers examine the metabolic effects of an oral blood cancer drug

by The Mount Sinai HospitalCredit: CC0 Public DomainA popular cancer drug is associated with significant weight gain and increased systolic blood pressure, researchers from the Icahn School of Me

Updated on: June 15,2024

Researchers examine the metabolic effects of an oral blood cancer drug

by The Mount Sinai HospitalCredit: CC0 Public DomainA popular cancer drug is associated with significant weight gain and increased systolic blood pressure, researchers from the Icahn School of Me

Updated on:June 15,2024

Researcher looks at molecular changes for clues to disparities in breast cancer outcomes

by Medical University of South CarolinaPeggi Angel, Ph.D., is in looking at how socioeconomic stressors may influence metabolic processes that could in turn create a "tumor permissive"

Updated on: February 18,2024

Researcher looks at molecular changes for clues to disparities in breast cancer outcomes

by Medical University of South CarolinaPeggi Angel, Ph.D., is in looking at how socioeconomic stressors may influence metabolic processes that could in turn create a "tumor permissive"

Updated on:February 18,2024