Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024

Actinidia arguta (sarunashi) juice found to inhibit lung cancer in mice

byOkayama UniversityA representative tumor (adenoma/adenocarcinoma) corresponding to the nodule counted macroscopically and the alveolar area around the tumor in the A/J mouse at 30 weeks of age

Updated on: January 02,2024

Actinidia arguta (sarunashi) juice found to inhibit lung cancer in mice

byOkayama UniversityA representative tumor (adenoma/adenocarcinoma) corresponding to the nodule counted macroscopically and the alveolar area around the tumor in the A/J mouse at 30 weeks of age

Updated on:January 02,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on: January 30,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on:January 30,2024

Study uncovers how B cells react to skin cancer

by King's College LondonSpatial transcriptomic coupled with high throughput intratumoral antibody repertoire analyses suggest an active but aberrant B cell response.aRepresentativ

Updated on: February 23,2024

Study uncovers how B cells react to skin cancer

by King's College LondonSpatial transcriptomic coupled with high throughput intratumoral antibody repertoire analyses suggest an active but aberrant B cell response.aRepresentativ

Updated on:February 23,2024

Key human bladder cancer genes pinpointed in cats and dogs

by Wellcome Trust Sanger InstituteCredit: Unsplash/CC0 Public DomainKey bladder cancer genes have been uncovered through studying the cancers in cats and dogs, in a significant stride for finding

Updated on: February 03,2024

Key human bladder cancer genes pinpointed in cats and dogs

by Wellcome Trust Sanger InstituteCredit: Unsplash/CC0 Public DomainKey bladder cancer genes have been uncovered through studying the cancers in cats and dogs, in a significant stride for finding

Updated on:February 03,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on: March 08,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on:March 08,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on: June 15,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on:June 15,2024

Researchers convert pro-tumor macrophages into cancer killers

by University of California - San DiegoCredit: CC0 Public DomainEpithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer ther

Updated on: June 15,2024

Researchers convert pro-tumor macrophages into cancer killers

by University of California - San DiegoCredit: CC0 Public DomainEpithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer ther

Updated on:June 15,2024

Active surveillance feasible for small, low-grade bladder cancer

(HealthDay)—For patients who present with small, low-grade pTa/pT1a recurrent papillary bladder tumors, active surveillance appears to be a reasonable strategy, according to a study published in the F

Updated on: April 07,2024

Active surveillance feasible for small, low-grade bladder cancer

(HealthDay)—For patients who present with small, low-grade pTa/pT1a recurrent papillary bladder tumors, active surveillance appears to be a reasonable strategy, according to a study published in the F

Updated on:April 07,2024

Occupational health study links air pollution and cancer

by University of StirlingCredit: CC0 Public DomainUniversity of Stirling experts have discovered new evidence of the link between air pollution and cancer as part of a new occupational health stu

Updated on: April 10,2024

Occupational health study links air pollution and cancer

by University of StirlingCredit: CC0 Public DomainUniversity of Stirling experts have discovered new evidence of the link between air pollution and cancer as part of a new occupational health stu

Updated on:April 10,2024

Novel prognostic index to predict survival outcomes in gastric cancer patients

by Impact Journals LLCCancer-specific survival curve based on the inflammation-based prognostic index. Abbreviation: ICPI: inflammation based prognostic index. Credit:Oncotarget(2023). DOI

Updated on: January 30,2024

Novel prognostic index to predict survival outcomes in gastric cancer patients

by Impact Journals LLCCancer-specific survival curve based on the inflammation-based prognostic index. Abbreviation: ICPI: inflammation based prognostic index. Credit:Oncotarget(2023). DOI

Updated on:January 30,2024

Long-term cardiomyopathy risk varies by chemo agent

(HealthDay)—Long-term cardiomyopathy risk varies by chemotherapy agent for childhood cancer survivors, with a decreased risk for daunorubicin versus doxorubicin, according to a study recently publishe

Updated on: April 18,2024

Long-term cardiomyopathy risk varies by chemo agent

(HealthDay)—Long-term cardiomyopathy risk varies by chemotherapy agent for childhood cancer survivors, with a decreased risk for daunorubicin versus doxorubicin, according to a study recently publishe

Updated on:April 18,2024