Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on: March 30,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on:March 30,2024

Virus linked to cancer takes over 'cellular mail' to alter tumor environment

by University of North Carolina at Chapel Hill School of MedicineRyan P. McNamara, PhD, is a postdoctoral research associate at UNC Lineberger. Credit: University of North Carolina at Chapel Hill

Updated on: May 07,2024

Virus linked to cancer takes over 'cellular mail' to alter tumor environment

by University of North Carolina at Chapel Hill School of MedicineRyan P. McNamara, PhD, is a postdoctoral research associate at UNC Lineberger. Credit: University of North Carolina at Chapel Hill

Updated on:May 07,2024

Researchers to test novel drug combination against toughest breast cancers

by University of California - San DiegoThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: National Ins

Updated on: June 15,2024

Researchers to test novel drug combination against toughest breast cancers

by University of California - San DiegoThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: National Ins

Updated on:June 15,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on: April 07,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on:April 07,2024

Treatment beneficial for nonagenarians with lung cancer

(HealthDay)—Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a st

Updated on: April 10,2024

Treatment beneficial for nonagenarians with lung cancer

(HealthDay)—Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a st

Updated on:April 10,2024

Researcher helps define subtypes of ovarian cancer

by The City University of New YorkCredit: CC0 Public DomainIn a new paper published in the journalClinical Cancer Research, CUNY SPH Associate Professor Levi Waldron and colleagues resolved

Updated on: March 06,2024

Researcher helps define subtypes of ovarian cancer

by The City University of New YorkCredit: CC0 Public DomainIn a new paper published in the journalClinical Cancer Research, CUNY SPH Associate Professor Levi Waldron and colleagues resolved

Updated on:March 06,2024

Pancreatic cancer's addiction could be its end

by Cold Spring Harbor LaboratoryThe researchers looked for various indicators of tumor activity in normal pancreas cells (top row) comparing results to those from when the production of the P63 p

Updated on: May 13,2024

Pancreatic cancer's addiction could be its end

by Cold Spring Harbor LaboratoryThe researchers looked for various indicators of tumor activity in normal pancreas cells (top row) comparing results to those from when the production of the P63 p

Updated on:May 13,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on: March 08,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on:March 08,2024

Researchers convert pro-tumor macrophages into cancer killers

by University of California - San DiegoCredit: CC0 Public DomainEpithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer ther

Updated on: June 15,2024

Researchers convert pro-tumor macrophages into cancer killers

by University of California - San DiegoCredit: CC0 Public DomainEpithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer ther

Updated on:June 15,2024

A new tool to study cell movement promises to advance cancer research

by University of MinnesotaOverview and validation of RAD-TGT function in CHO-K1 cells.aConceptual schematic of the force-induced rupture and readout of RAD-TGTs.bBrightfie

Updated on: February 18,2024

A new tool to study cell movement promises to advance cancer research

by University of MinnesotaOverview and validation of RAD-TGT function in CHO-K1 cells.aConceptual schematic of the force-induced rupture and readout of RAD-TGTs.bBrightfie

Updated on:February 18,2024

Researchers uncover novel gene that regulates leukemia development and progression

by Pusan National UniversityResearchers from Pusan National University find that suppressing the expression of SURF4 reduces pathologic processes that contribute to leukemia progression. Credit: Profe

Updated on: February 23,2024

Researchers uncover novel gene that regulates leukemia development and progression

by Pusan National UniversityResearchers from Pusan National University find that suppressing the expression of SURF4 reduces pathologic processes that contribute to leukemia progression. Credit: Profe

Updated on:February 23,2024

A code for reprogramming immune sentinels

by Lund UniversityArtistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Credit: National Institutes of Health (NI

Updated on: May 23,2024

A code for reprogramming immune sentinels

by Lund UniversityArtistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Credit: National Institutes of Health (NI

Updated on:May 23,2024