Researchers suggest new way to target third most common oncogene, TERT

by Garth Sundem,CU Anschutz Medical CampusChromosome, showing telomeres in pink. Credit: CUHealthy cells have a built-in self-destruct mechanism: Strands of DNA called "telomeres" act

Updated on: March 01,2024

Researchers suggest new way to target third most common oncogene, TERT

by Garth Sundem,CU Anschutz Medical CampusChromosome, showing telomeres in pink. Credit: CUHealthy cells have a built-in self-destruct mechanism: Strands of DNA called "telomeres" act

Updated on:March 01,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on: January 30,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on:January 30,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on: June 06,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on:June 06,2024

Researchers develop novel gold-nanocluster-based tumor radiodynamic therapy

by Zhang Nannan,Chinese Academy of SciencesGold-nanocluster-based radiodynamic therapy. Credit: IGDBRadiotherapy (RT) is a primary method of tumor treatment. However, in clinical practice, radio

Updated on: February 01,2024

Researchers develop novel gold-nanocluster-based tumor radiodynamic therapy

by Zhang Nannan,Chinese Academy of SciencesGold-nanocluster-based radiodynamic therapy. Credit: IGDBRadiotherapy (RT) is a primary method of tumor treatment. However, in clinical practice, radio

Updated on:February 01,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on: June 04,2024

Researchers find effective drug combinations for glioblastoma in mice

by The Spanish National Cancer Research CentreTelomeres (red) in mouse embryonic fibroblasts; DNA damage (green) caused by ERK inhibition. ERK is an enzyme in the RAS pathway whose inhibition lea

Updated on:June 04,2024

Researchers find a 'critical need' for whole genome sequencing of young cancer patients

by St. Jude Children's Research HospitalSt. Jude investigators (from left) Michael Rusch, Sheila Shurtleff, Ph.D., Jinghui Zhang, Ph.D., and Scott Newman, Ph.D. Credit: St. Jude Children'

Updated on: June 22,2024

Researchers find a 'critical need' for whole genome sequencing of young cancer patients

by St. Jude Children's Research HospitalSt. Jude investigators (from left) Michael Rusch, Sheila Shurtleff, Ph.D., Jinghui Zhang, Ph.D., and Scott Newman, Ph.D. Credit: St. Jude Children'

Updated on:June 22,2024

Research quantifies effect of chronic diseases on racial disparity in COVID-associated hospitalizations

by Louisiana State UniversityCredit: CC0 Public DomainLSU Health New Orleans conducted the first research using disease surveillance data to quantify the effect of chronic diseases on racial disp

Updated on: June 28,2024

Research quantifies effect of chronic diseases on racial disparity in COVID-associated hospitalizations

by Louisiana State UniversityCredit: CC0 Public DomainLSU Health New Orleans conducted the first research using disease surveillance data to quantify the effect of chronic diseases on racial disp

Updated on:June 28,2024

Researchers identify genes that cause rare hidden cancer

by Garvan Institute of Medical ResearchIHC staining of human sarcoma cells (myxoid liposarcoma). Credit: Garvan Institute of Medical ResearchSeveral genes that cause sarcoma have been identified

Updated on: February 23,2024

Researchers identify genes that cause rare hidden cancer

by Garvan Institute of Medical ResearchIHC staining of human sarcoma cells (myxoid liposarcoma). Credit: Garvan Institute of Medical ResearchSeveral genes that cause sarcoma have been identified

Updated on:February 23,2024

Researchers clarify role of mutations in glioblastoma

by University of North Carolina at Chapel Hill School of MedicineLaboratory models with a mutated PIK3CA gene showed characteristics of gliomas. Credit: McNeill, RS, et al.,PLOS ONE.Researc

Updated on: June 24,2024

Researchers clarify role of mutations in glioblastoma

by University of North Carolina at Chapel Hill School of MedicineLaboratory models with a mutated PIK3CA gene showed characteristics of gliomas. Credit: McNeill, RS, et al.,PLOS ONE.Researc

Updated on:June 24,2024

AI effective in diagnosis of head and neck cancer, finds researcher

by Claes Björnberg,Umea UniversityCredit: Pixabay/CC0 Public DomainStudies in a new doctoral thesis indicate that an AI-supported method is effective in the diagnosis of squamous cell carcinoma

Updated on: February 01,2024

AI effective in diagnosis of head and neck cancer, finds researcher

by Claes Björnberg,Umea UniversityCredit: Pixabay/CC0 Public DomainStudies in a new doctoral thesis indicate that an AI-supported method is effective in the diagnosis of squamous cell carcinoma

Updated on:February 01,2024

Researchers shed light on signaling pathway responsible for head and neck cancers

by Gina DiGravio,Boston University School of MedicineCausal Inference Models of Interactions Between Pathways/Cell States in Head and Neck Cancer scRNAseq Data. A. Causal inference graphs indica

Updated on: February 18,2024

Researchers shed light on signaling pathway responsible for head and neck cancers

by Gina DiGravio,Boston University School of MedicineCausal Inference Models of Interactions Between Pathways/Cell States in Head and Neck Cancer scRNAseq Data. A. Causal inference graphs indica

Updated on:February 18,2024

Researcher discusses how lung macrophages evolve during metastatic growth of lung colonies in a mouse model of melanoma

by Impact Journals LLCCredit: Unsplash/CC0 Public DomainA new editorial paper titled "A macrophage is a macrophage is a macrophage—in metastasis" has been published inOncotarget.In thi

Updated on: February 18,2024

Researcher discusses how lung macrophages evolve during metastatic growth of lung colonies in a mouse model of melanoma

by Impact Journals LLCCredit: Unsplash/CC0 Public DomainA new editorial paper titled "A macrophage is a macrophage is a macrophage—in metastasis" has been published inOncotarget.In thi

Updated on:February 18,2024