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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Prostate tumor biology may be influenced by genetic ancestry

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to
The search to discover why 'outliers' survive deadliest cancers

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of
Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has
Treatment strategy for locally advanced liver cancer via novel tri-modality therapy

Treatment strategy for locally advanced liver cancer via novel tri-modality therapy

byThe University of Hong KongCredit: Pixabay/CC0 Public DomainA pioneering phase II clinical study on tri-modality therapy (START-FIT), conducted by the Department of Surgery and Department of C

Treatment strategy for locally advanced liver cancer via novel tri-modality therapy

byThe University of Hong KongCredit: Pixabay/CC0 Public DomainA pioneering phase II clinical study on tri-modality therapy (START-FIT), conducted by the Department of Surgery and Department of C
Experts boost activity of potential therapeutic target in triple-negative breast cancer

Experts boost activity of potential therapeutic target in triple-negative breast cancer

by Diana Yates,University of Illinois at Urbana-ChampaignCredit: Unsplash/CC0 Public DomainLess than 20% of diagnosed breast cancers are designated "triple-negative," lacking three typ

Experts boost activity of potential therapeutic target in triple-negative breast cancer

by Diana Yates,University of Illinois at Urbana-ChampaignCredit: Unsplash/CC0 Public DomainLess than 20% of diagnosed breast cancers are designated "triple-negative," lacking three typ
Treatment beneficial for nonagenarians with lung cancer

Treatment beneficial for nonagenarians with lung cancer

(HealthDay)—Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a st

Treatment beneficial for nonagenarians with lung cancer

(HealthDay)—Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a st
Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr
Two for the price of one: Mechanistic insights lead to drug repositioning

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc
Novel prognostic index to predict survival outcomes in gastric cancer patients

Novel prognostic index to predict survival outcomes in gastric cancer patients

by Impact Journals LLCCancer-specific survival curve based on the inflammation-based prognostic index. Abbreviation: ICPI: inflammation based prognostic index. Credit:Oncotarget(2023). DOI

Novel prognostic index to predict survival outcomes in gastric cancer patients

by Impact Journals LLCCancer-specific survival curve based on the inflammation-based prognostic index. Abbreviation: ICPI: inflammation based prognostic index. Credit:Oncotarget(2023). DOI
Researchers identify potential new combination treatment for pancreatic cancer

Researchers identify potential new combination treatment for pancreatic cancer

by Denise Heady,University of California, Los AngelesPancreatic cancer (the cancer cells are seen here) is the third leading cause of cancer-related deaths in the United States. Credit: Universi

Researchers identify potential new combination treatment for pancreatic cancer

by Denise Heady,University of California, Los AngelesPancreatic cancer (the cancer cells are seen here) is the third leading cause of cancer-related deaths in the United States. Credit: Universi
When should NHS contact patients over faulty genes?

When should NHS contact patients over faulty genes?

by University of ExeterCredit: CC0 Public DomainThe NHS and health services worldwide need to develop policies on when patients should be "re-contacted" about faulty genes, as the curre

When should NHS contact patients over faulty genes?

by University of ExeterCredit: CC0 Public DomainThe NHS and health services worldwide need to develop policies on when patients should be "re-contacted" about faulty genes, as the curre
Study identifies new gene that drives colon cancer

Study identifies new gene that drives colon cancer

by The Mount Sinai HospitalRecurrently dysregulated super-enhancers in CRC patients.aStudy overview. Figure adapted from SMART Servier Medical Art, reproduced with permission, license

Study identifies new gene that drives colon cancer

by The Mount Sinai HospitalRecurrently dysregulated super-enhancers in CRC patients.aStudy overview. Figure adapted from SMART Servier Medical Art, reproduced with permission, license