Study shows novel agent can overcome immune dysfunction in cancer

by Roswell Park Comprehensive Cancer CenterVSSP restores myeloid cell frequencies following leukopenia. C57BL/6 mice were injected with CY (200 mg/kg body weight, i.p.) and with two consecutive daily

Updated on: January 22,2024

Study shows novel agent can overcome immune dysfunction in cancer

by Roswell Park Comprehensive Cancer CenterVSSP restores myeloid cell frequencies following leukopenia. C57BL/6 mice were injected with CY (200 mg/kg body weight, i.p.) and with two consecutive daily

Updated on:January 22,2024

Metastasizing cancer cells modify bone remodeling with small RNA secretion

by Tokyo Medical and Dental UniversityIn the bone metastatic microenvironment, the crosstalk between metastasized cancer cells and the surrounding bone cells is critical for the formation of the osteo

Updated on: April 01,2024

Metastasizing cancer cells modify bone remodeling with small RNA secretion

by Tokyo Medical and Dental UniversityIn the bone metastatic microenvironment, the crosstalk between metastasized cancer cells and the surrounding bone cells is critical for the formation of the osteo

Updated on:April 01,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on: January 30,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on:January 30,2024

Researcher helps define subtypes of ovarian cancer

by The City University of New YorkCredit: CC0 Public DomainIn a new paper published in the journalClinical Cancer Research, CUNY SPH Associate Professor Levi Waldron and colleagues resolved

Updated on: March 06,2024

Researcher helps define subtypes of ovarian cancer

by The City University of New YorkCredit: CC0 Public DomainIn a new paper published in the journalClinical Cancer Research, CUNY SPH Associate Professor Levi Waldron and colleagues resolved

Updated on:March 06,2024

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

Updated on: April 22,2024

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

Updated on:April 22,2024

Researchers develop novel gold-nanocluster-based tumor radiodynamic therapy

by Zhang Nannan,Chinese Academy of SciencesGold-nanocluster-based radiodynamic therapy. Credit: IGDBRadiotherapy (RT) is a primary method of tumor treatment. However, in clinical practice, radio

Updated on: February 01,2024

Researchers develop novel gold-nanocluster-based tumor radiodynamic therapy

by Zhang Nannan,Chinese Academy of SciencesGold-nanocluster-based radiodynamic therapy. Credit: IGDBRadiotherapy (RT) is a primary method of tumor treatment. However, in clinical practice, radio

Updated on:February 01,2024

New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

by Impact Journals LLCMDSCs generated by obesity migrate to lymphoid organ and TME. Credit: 2022 Shibata et al.A new review titled "Myeloid-derived suppressor cells: Cancer, autoimmune diseases,

Updated on: January 12,2024

New research reviews myeloid-derived suppressor cells in cancer, autoimmune diseases, and more

by Impact Journals LLCMDSCs generated by obesity migrate to lymphoid organ and TME. Credit: 2022 Shibata et al.A new review titled "Myeloid-derived suppressor cells: Cancer, autoimmune diseases,

Updated on:January 12,2024

Working toward personalized cancer treatment

by Weizmann Institute of ScienceProf. Yardena Samuels wants to reveal the big cancer picture. Credit: Weizmann Institute of Science"We don't just want to find the genes involved in cance

Updated on: April 09,2024

Working toward personalized cancer treatment

by Weizmann Institute of ScienceProf. Yardena Samuels wants to reveal the big cancer picture. Credit: Weizmann Institute of Science"We don't just want to find the genes involved in cance

Updated on:April 09,2024

One sigmoidoscopy significantly reduces long-term CRC incidence in both men and women

by American College of PhysiciansCredit: Pixabay/CC0 Public DomainA pooled analysis evaluating the 15-year effect of sigmoidoscopies has found that receiving one sigmoidoscopy significantly reduc

Updated on: January 30,2024

One sigmoidoscopy significantly reduces long-term CRC incidence in both men and women

by American College of PhysiciansCredit: Pixabay/CC0 Public DomainA pooled analysis evaluating the 15-year effect of sigmoidoscopies has found that receiving one sigmoidoscopy significantly reduc

Updated on:January 30,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on: June 15,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on:June 15,2024

Researchers uncover potential biomarkers of positive response to immunotherapy

by Denise Heady,University of California, Los AngelesResponse to ICI or MAPKi therapy is associated with increased T cell infiltration and enhanced interferon gamma (IFNγ) pathway activity in th

Updated on: January 30,2024

Researchers uncover potential biomarkers of positive response to immunotherapy

by Denise Heady,University of California, Los AngelesResponse to ICI or MAPKi therapy is associated with increased T cell infiltration and enhanced interferon gamma (IFNγ) pathway activity in th

Updated on:January 30,2024

Researchers develop antibodies that alleviate 'cancer cachexia' in patients

by Daegu Gyeongbuk Institute of Science and TechnologyCredit: Daegu Gyeongbuk Institute of Science and TechnologyA DGIST research team led by Professor Kyungmoo Yea of the Department of New Biology de

Updated on: February 01,2024

Researchers develop antibodies that alleviate 'cancer cachexia' in patients

by Daegu Gyeongbuk Institute of Science and TechnologyCredit: Daegu Gyeongbuk Institute of Science and TechnologyA DGIST research team led by Professor Kyungmoo Yea of the Department of New Biology de

Updated on:February 01,2024