Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on: March 30,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on:March 30,2024

Pancreatic cancer's addiction could be its end

by Cold Spring Harbor LaboratoryThe researchers looked for various indicators of tumor activity in normal pancreas cells (top row) comparing results to those from when the production of the P63 p

Updated on: May 13,2024

Pancreatic cancer's addiction could be its end

by Cold Spring Harbor LaboratoryThe researchers looked for various indicators of tumor activity in normal pancreas cells (top row) comparing results to those from when the production of the P63 p

Updated on:May 13,2024

New study indicates treatment patterns, not genetics, drive prostate cancer disparities

by Sylvester Comprehensive Cancer CenterOverview of study design and overall genomic landscape (A) Study overview. The study comprised 11 741 patients with prostate cancer who underwent CGP to assess

Updated on: January 12,2024

New study indicates treatment patterns, not genetics, drive prostate cancer disparities

by Sylvester Comprehensive Cancer CenterOverview of study design and overall genomic landscape (A) Study overview. The study comprised 11 741 patients with prostate cancer who underwent CGP to assess

Updated on:January 12,2024

Researchers to test novel drug combination against toughest breast cancers

by University of California - San DiegoThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: National Ins

Updated on: June 15,2024

Researchers to test novel drug combination against toughest breast cancers

by University of California - San DiegoThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: National Ins

Updated on:June 15,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on: April 07,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on:April 07,2024

Researchers uncover novel gene that regulates leukemia development and progression

by Pusan National UniversityResearchers from Pusan National University find that suppressing the expression of SURF4 reduces pathologic processes that contribute to leukemia progression. Credit: Profe

Updated on: February 23,2024

Researchers uncover novel gene that regulates leukemia development and progression

by Pusan National UniversityResearchers from Pusan National University find that suppressing the expression of SURF4 reduces pathologic processes that contribute to leukemia progression. Credit: Profe

Updated on:February 23,2024

A code for reprogramming immune sentinels

by Lund UniversityArtistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Credit: National Institutes of Health (NI

Updated on: May 23,2024

A code for reprogramming immune sentinels

by Lund UniversityArtistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Credit: National Institutes of Health (NI

Updated on:May 23,2024

Researcher helps define subtypes of ovarian cancer

by The City University of New YorkCredit: CC0 Public DomainIn a new paper published in the journalClinical Cancer Research, CUNY SPH Associate Professor Levi Waldron and colleagues resolved

Updated on: March 06,2024

Researcher helps define subtypes of ovarian cancer

by The City University of New YorkCredit: CC0 Public DomainIn a new paper published in the journalClinical Cancer Research, CUNY SPH Associate Professor Levi Waldron and colleagues resolved

Updated on:March 06,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on: June 06,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on:June 06,2024

Too often, women aren't told of sexual side effects of cancer treatments

by Cara MurezWhen a man has cancer in an area that affects sexual function, his doctor is likely to discuss it with him.But the same is not true for a woman who has cancer in a sex organ, according to

Updated on: January 02,2024

Too often, women aren't told of sexual side effects of cancer treatments

by Cara MurezWhen a man has cancer in an area that affects sexual function, his doctor is likely to discuss it with him.But the same is not true for a woman who has cancer in a sex organ, according to

Updated on:January 02,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on: March 08,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on:March 08,2024

New study suggests way to predict outcomes with high accuracy prior to surgery for pancreatic cancer patients

by National Comprehensive Cancer NetworkPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteNew research in the September 2022 issue of&nbsp

Updated on: January 13,2024

New study suggests way to predict outcomes with high accuracy prior to surgery for pancreatic cancer patients

by National Comprehensive Cancer NetworkPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteNew research in the September 2022 issue of&nbsp

Updated on:January 13,2024