Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b

Updated on: June 22,2024

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b

Updated on:June 22,2024

Researcher looks at molecular changes for clues to disparities in breast cancer outcomes

by Medical University of South CarolinaPeggi Angel, Ph.D., is in looking at how socioeconomic stressors may influence metabolic processes that could in turn create a "tumor permissive"

Updated on: February 18,2024

Researcher looks at molecular changes for clues to disparities in breast cancer outcomes

by Medical University of South CarolinaPeggi Angel, Ph.D., is in looking at how socioeconomic stressors may influence metabolic processes that could in turn create a "tumor permissive"

Updated on:February 18,2024

Researchers develop 'on-demand' whole tumor cell vaccine against cancer

by Chinese Academy of SciencesStrategy of using photothermal nanoparticle-based whole tumor cell vaccine (LN-TCV) for on-demand near-infrared (NIR) manipulation of immune responses against cancer

Updated on: February 18,2024

Researchers develop 'on-demand' whole tumor cell vaccine against cancer

by Chinese Academy of SciencesStrategy of using photothermal nanoparticle-based whole tumor cell vaccine (LN-TCV) for on-demand near-infrared (NIR) manipulation of immune responses against cancer

Updated on:February 18,2024

Researchers clarify role of mutations in glioblastoma

by University of North Carolina at Chapel Hill School of MedicineLaboratory models with a mutated PIK3CA gene showed characteristics of gliomas. Credit: McNeill, RS, et al.,PLOS ONE.Researc

Updated on: June 24,2024

Researchers clarify role of mutations in glioblastoma

by University of North Carolina at Chapel Hill School of MedicineLaboratory models with a mutated PIK3CA gene showed characteristics of gliomas. Credit: McNeill, RS, et al.,PLOS ONE.Researc

Updated on:June 24,2024

Researchers develop antibodies that alleviate 'cancer cachexia' in patients

by Daegu Gyeongbuk Institute of Science and TechnologyCredit: Daegu Gyeongbuk Institute of Science and TechnologyA DGIST research team led by Professor Kyungmoo Yea of the Department of New Biology de

Updated on: February 01,2024

Researchers develop antibodies that alleviate 'cancer cachexia' in patients

by Daegu Gyeongbuk Institute of Science and TechnologyCredit: Daegu Gyeongbuk Institute of Science and TechnologyA DGIST research team led by Professor Kyungmoo Yea of the Department of New Biology de

Updated on:February 01,2024

Researchers report on inhibitory effect of glioblastoma signals to macrophages

by University of BaselGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0"Don't eat me," is how one might translate the signal that the cancer cells in a glioblastoma sen

Updated on: February 18,2024

Researchers report on inhibitory effect of glioblastoma signals to macrophages

by University of BaselGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0"Don't eat me," is how one might translate the signal that the cancer cells in a glioblastoma sen

Updated on:February 18,2024

Researchers demonstrate in mice a new way to deliver medication to malignant brain tumors

by Brown UniversityCredit:Journal of Controlled Release(2022). DOI: 10.1016/j.jconrel.2022.10.051Researchers have demonstrated in mice a new approach for delivering medication across

Updated on: February 18,2024

Researchers demonstrate in mice a new way to deliver medication to malignant brain tumors

by Brown UniversityCredit:Journal of Controlled Release(2022). DOI: 10.1016/j.jconrel.2022.10.051Researchers have demonstrated in mice a new approach for delivering medication across

Updated on:February 18,2024

Researchers convert pro-tumor macrophages into cancer killers

by University of California - San DiegoCredit: CC0 Public DomainEpithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer ther

Updated on: June 15,2024

Researchers convert pro-tumor macrophages into cancer killers

by University of California - San DiegoCredit: CC0 Public DomainEpithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer ther

Updated on:June 15,2024

Researchers detect a loophole in chronic lymphocytic leukemia treatment

by Rockefeller University PressThe adhesive protein CD49d (red) is present on the surface of these adherent chronic lymphocytic leukemia cells. Credit: Tissino et al., 2018A team of researchers i

Updated on: March 01,2024

Researchers detect a loophole in chronic lymphocytic leukemia treatment

by Rockefeller University PressThe adhesive protein CD49d (red) is present on the surface of these adherent chronic lymphocytic leukemia cells. Credit: Tissino et al., 2018A team of researchers i

Updated on:March 01,2024

Researcher helps define subtypes of ovarian cancer

by The City University of New YorkCredit: CC0 Public DomainIn a new paper published in the journalClinical Cancer Research, CUNY SPH Associate Professor Levi Waldron and colleagues resolved

Updated on: March 06,2024

Researcher helps define subtypes of ovarian cancer

by The City University of New YorkCredit: CC0 Public DomainIn a new paper published in the journalClinical Cancer Research, CUNY SPH Associate Professor Levi Waldron and colleagues resolved

Updated on:March 06,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on: June 06,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on:June 06,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on: March 30,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on:March 30,2024