The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of

Updated on: March 30,2024

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of

Updated on:March 30,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on: March 08,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on:March 08,2024

Targeted care reverses racial/ethnic health disparities in colon cancer screening, researchers find

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainColorectal cancer is a leading cancer-related cause of death in the United States, ranking third in in

Updated on: January 29,2024

Targeted care reverses racial/ethnic health disparities in colon cancer screening, researchers find

by Jacqueline Mitchell,Beth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainColorectal cancer is a leading cancer-related cause of death in the United States, ranking third in in

Updated on:January 29,2024

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper

Updated on: January 11,2024

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper

Updated on:January 11,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on: April 07,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on:April 07,2024

An ancient signaling pathway and 20 years of research offer hope for rare cancer

byPeter MacCallum Cancer CentreCredit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00217-3Researchers at Peter Mac are using their knowledge of an ancient signaling pathway to find ne

Updated on: September 07,2024

An ancient signaling pathway and 20 years of research offer hope for rare cancer

byPeter MacCallum Cancer CentreCredit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00217-3Researchers at Peter Mac are using their knowledge of an ancient signaling pathway to find ne

Updated on:September 07,2024

Researchers solving treatment resistance in most common breast cancer

by University of Pittsburgh Schools of the Health SciencesMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainAt Magee-Womens Research Institute (MWRI

Updated on: March 01,2024

Researchers solving treatment resistance in most common breast cancer

by University of Pittsburgh Schools of the Health SciencesMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainAt Magee-Womens Research Institute (MWRI

Updated on:March 01,2024

Drugmaker GSK says EU to review womb cancer treatment

Credit: Unsplash/CC0 Public DomainBritish pharmaceutical giant GSK said on Tuesday that the EU's drug watchdog will study a new treatment for a common type of womb cancer for potential approval in

Updated on: January 30,2024

Drugmaker GSK says EU to review womb cancer treatment

Credit: Unsplash/CC0 Public DomainBritish pharmaceutical giant GSK said on Tuesday that the EU's drug watchdog will study a new treatment for a common type of womb cancer for potential approval in

Updated on:January 30,2024

Researchers map genetic signature of precursor to liver cancer

by Curtin UniversityProfessor Nina Tirnitz-Parker and Dr. Rodrigo Carlessi, from Curtin University. Credit: Curtin UniversityResearchers at Curtin University have identified the genetic signature

Updated on: February 24,2024

Researchers map genetic signature of precursor to liver cancer

by Curtin UniversityProfessor Nina Tirnitz-Parker and Dr. Rodrigo Carlessi, from Curtin University. Credit: Curtin UniversityResearchers at Curtin University have identified the genetic signature

Updated on:February 24,2024

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

Updated on: April 22,2024

New regulator in aggressive breast cancer cells discovered

by Leibniz Institute on AgingThe protein TRPS1 controls the activity of the YAP protein in breast cancer. If YAP activity is downregulated, the survival prognosis for patients is reduced. If TRPS1 is

Updated on:April 22,2024

Pancreatic cancer's addiction could be its end

by Cold Spring Harbor LaboratoryThe researchers looked for various indicators of tumor activity in normal pancreas cells (top row) comparing results to those from when the production of the P63 p

Updated on: May 13,2024

Pancreatic cancer's addiction could be its end

by Cold Spring Harbor LaboratoryThe researchers looked for various indicators of tumor activity in normal pancreas cells (top row) comparing results to those from when the production of the P63 p

Updated on:May 13,2024

Exercise testing detects silent cardiovascular dangers common in pediatric cancer survivors

by Nemours Children's Health SystemCredit: Pixabay/CC0 Public DomainCardiopulmonary exercise testing (CPET) can detect underlying early signs of cardiovascular problems in asymptomatic pediat

Updated on: February 18,2024

Exercise testing detects silent cardiovascular dangers common in pediatric cancer survivors

by Nemours Children's Health SystemCredit: Pixabay/CC0 Public DomainCardiopulmonary exercise testing (CPET) can detect underlying early signs of cardiovascular problems in asymptomatic pediat

Updated on:February 18,2024