Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024

Malpractice trends involving active surveillance across cancers

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainActive surveillance is an established practice for managing certain low-risk cancers that are unlikely to cause harm. It is an increasingly

Updated on: March 30,2024

Malpractice trends involving active surveillance across cancers

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainActive surveillance is an established practice for managing certain low-risk cancers that are unlikely to cause harm. It is an increasingly

Updated on:March 30,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on: March 30,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on:March 30,2024

Unemployment due to brain or spine cancer is linked to more pain and depression

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople who are unemployed due to brain or spine cancer may experience more severe symptoms of pain, discomfort, anxiety and depres

Updated on: January 02,2024

Unemployment due to brain or spine cancer is linked to more pain and depression

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainPeople who are unemployed due to brain or spine cancer may experience more severe symptoms of pain, discomfort, anxiety and depres

Updated on:January 02,2024

Types of bacteria vary widely in tumors of people with early vs. late-onset colorectal cancer

by Georgetown University Medical CenterCredit: Pixabay/CC0 Public DomainResearchers at Georgetown University's Lombardi Comprehensive Cancer Center studied the microbiome of people with color

Updated on: January 30,2024

Types of bacteria vary widely in tumors of people with early vs. late-onset colorectal cancer

by Georgetown University Medical CenterCredit: Pixabay/CC0 Public DomainResearchers at Georgetown University's Lombardi Comprehensive Cancer Center studied the microbiome of people with color

Updated on:January 30,2024

New imaging technology for diagnosing and treating bowel cancer patients

byUniversity of GlasgowRepresentative transverse PET images from each mouse model and tracer. Credit:Clinical Cancer Research(2024). DOI: 10.1158/1078-0432.CCR-23-1063Biopsies are cu

Updated on: March 30,2024

New imaging technology for diagnosing and treating bowel cancer patients

byUniversity of GlasgowRepresentative transverse PET images from each mouse model and tracer. Credit:Clinical Cancer Research(2024). DOI: 10.1158/1078-0432.CCR-23-1063Biopsies are cu

Updated on:March 30,2024

Researchers discover a new mechanism of cancer immune defense

by Universitätsmedizin MagdeburgGraphical summary of inflammatory cell death induction of MHC-deficient and IFN-unresponsive tumors by CD4+ T cells in cooperation with iNOS-expressing myeloid cells. C

Updated on: February 01,2024

Researchers discover a new mechanism of cancer immune defense

by Universitätsmedizin MagdeburgGraphical summary of inflammatory cell death induction of MHC-deficient and IFN-unresponsive tumors by CD4+ T cells in cooperation with iNOS-expressing myeloid cells. C

Updated on:February 01,2024

Researchers to test novel drug combination against toughest breast cancers

by University of California - San DiegoThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: National Ins

Updated on: June 15,2024

Researchers to test novel drug combination against toughest breast cancers

by University of California - San DiegoThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: National Ins

Updated on:June 15,2024

Oncolytic virus treatment produces promising results in patients with triple-negative breast cancer

byH. Lee Moffitt Cancer Center & Research InstituteCredit: Unsplash/CC0 Public DomainTriple-negative breast cancer accounts for approximately 15% of all breast cancer cases. Patients with th

Updated on: January 02,2024

Oncolytic virus treatment produces promising results in patients with triple-negative breast cancer

byH. Lee Moffitt Cancer Center & Research InstituteCredit: Unsplash/CC0 Public DomainTriple-negative breast cancer accounts for approximately 15% of all breast cancer cases. Patients with th

Updated on:January 02,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on: June 06,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on:June 06,2024

Key human bladder cancer genes pinpointed in cats and dogs

by Wellcome Trust Sanger InstituteCredit: Unsplash/CC0 Public DomainKey bladder cancer genes have been uncovered through studying the cancers in cats and dogs, in a significant stride for finding

Updated on: February 03,2024

Key human bladder cancer genes pinpointed in cats and dogs

by Wellcome Trust Sanger InstituteCredit: Unsplash/CC0 Public DomainKey bladder cancer genes have been uncovered through studying the cancers in cats and dogs, in a significant stride for finding

Updated on:February 03,2024

Over half of English patients with NSCLC in areas with low socio-economic levels do not receive anti-cancer therapies

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainNovel anti-cancer therapies were not accessible to more than half of the patients in England who were diagnose

Updated on: February 01,2024

Over half of English patients with NSCLC in areas with low socio-economic levels do not receive anti-cancer therapies

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainNovel anti-cancer therapies were not accessible to more than half of the patients in England who were diagnose

Updated on:February 01,2024