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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Clinical trial examines standard vs. extended lymph node removal for muscle-invasive bladder cancer

Clinical trial examines standard vs. extended lymph node removal for muscle-invasive bladder cancer

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainFinal results from the SWOG S1011 randomized Phase III clinical trial, published in theNew England Journal of Medicine, indicate p

Clinical trial examines standard vs. extended lymph node removal for muscle-invasive bladder cancer

by SWOG Cancer Research NetworkCredit: Pixabay/CC0 Public DomainFinal results from the SWOG S1011 randomized Phase III clinical trial, published in theNew England Journal of Medicine, indicate p
Re-engineered, blue light-activated immune cells penetrate and kill solid tumors

Re-engineered, blue light-activated immune cells penetrate and kill solid tumors

byPennsylvania State UniversityMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteImmunotherapies that mobilize a pati

Re-engineered, blue light-activated immune cells penetrate and kill solid tumors

byPennsylvania State UniversityMyeloid immune cells alongsidered blood cells in an electron micrograph of human blood. Credit: National Cancer InstituteImmunotherapies that mobilize a pati
Trial finds adding immunotherapy to neoadjuvant chemoradiation may improve outcomes in esophageal cancer

Trial finds adding immunotherapy to neoadjuvant chemoradiation may improve outcomes in esophageal cancer

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainA studypublishedinClinical Cancer Researchfound that in patients with unresectable, locally advanced

Trial finds adding immunotherapy to neoadjuvant chemoradiation may improve outcomes in esophageal cancer

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainA studypublishedinClinical Cancer Researchfound that in patients with unresectable, locally advanced
'Synthetic immune niche' approach enhances T-cell proliferation without compromising cancer-killing ability

'Synthetic immune niche' approach enhances T-cell proliferation without compromising cancer-killing ability

byWeizmann Institute of ScienceComparison of the significant differences in gene expression profiles between DC-activated cells (orange dots) and bead-activated cells (black dots) on their '

'Synthetic immune niche' approach enhances T-cell proliferation without compromising cancer-killing ability

byWeizmann Institute of ScienceComparison of the significant differences in gene expression profiles between DC-activated cells (orange dots) and bead-activated cells (black dots) on their '
Researchers clarify role of mutations in glioblastoma

Researchers clarify role of mutations in glioblastoma

by University of North Carolina at Chapel Hill School of MedicineLaboratory models with a mutated PIK3CA gene showed characteristics of gliomas. Credit: McNeill, RS, et al.,PLOS ONE.Researc

Researchers clarify role of mutations in glioblastoma

by University of North Carolina at Chapel Hill School of MedicineLaboratory models with a mutated PIK3CA gene showed characteristics of gliomas. Credit: McNeill, RS, et al.,PLOS ONE.Researc
Meta-analysis links high-risk Epstein-Barr virus lineage to nasopharyngeal cancer in southern China

Meta-analysis links high-risk Epstein-Barr virus lineage to nasopharyngeal cancer in southern China

byThe University of Hong KongPhylogenetic and population structure analysis. Credit:PLOS Pathogens(2024). DOI: 10.1371/journal.ppat.1012263Researchers at the LKS Faculty of Medicine

Meta-analysis links high-risk Epstein-Barr virus lineage to nasopharyngeal cancer in southern China

byThe University of Hong KongPhylogenetic and population structure analysis. Credit:PLOS Pathogens(2024). DOI: 10.1371/journal.ppat.1012263Researchers at the LKS Faculty of Medicine
Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma

Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma

byAmerican Society of HematologyCredit: Pixabay/CC0 Public DomainIn the first study to report real-world outcomes from ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR)-T

Cilta-cel found highly effective in first real-world study of patients with relapsed or refractory multiple myeloma

byAmerican Society of HematologyCredit: Pixabay/CC0 Public DomainIn the first study to report real-world outcomes from ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor (CAR)-T
Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy

Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy

byCleveland ClinicNeoantigen screening design and genomic features of NSCLC cohort.a, WES was performed onn= 58 pre-therapy samples andn= 42 on-therapy samples, whi

Researchers build first large-scale atlas of how immune cells react to mutations during cancer immunotherapy

byCleveland ClinicNeoantigen screening design and genomic features of NSCLC cohort.a, WES was performed onn= 58 pre-therapy samples andn= 42 on-therapy samples, whi
Trial: Standard chemoradiation superior to de-intensification approaches for HPV-related oropharyngeal cancer

Trial: Standard chemoradiation superior to de-intensification approaches for HPV-related oropharyngeal cancer

byAmerican Society for Radiation OncologyCredit: Unsplash/CC0 Public DomainResearchers looking to de-intensify radiation treatments for people with early-stage, HPV-associated oropharyngeal canc

Trial: Standard chemoradiation superior to de-intensification approaches for HPV-related oropharyngeal cancer

byAmerican Society for Radiation OncologyCredit: Unsplash/CC0 Public DomainResearchers looking to de-intensify radiation treatments for people with early-stage, HPV-associated oropharyngeal canc
New multimodal signature could predict immunotherapy success

New multimodal signature could predict immunotherapy success

byUniversity of InnsbruckCredit:iScience(2024). DOI: 10.1016/j.isci.2024.110529An international team of researchers led by Francesca Finotello from the Digital Science Center (DiSC)

New multimodal signature could predict immunotherapy success

byUniversity of InnsbruckCredit:iScience(2024). DOI: 10.1016/j.isci.2024.110529An international team of researchers led by Francesca Finotello from the Digital Science Center (DiSC)
Tiny tumor model recreates cancer metastasis

Tiny tumor model recreates cancer metastasis

by Rachel Harrison,New York UniversityClusters of about a hundred tumor cells labeled with red fluorescence were grown inside a transparent jelly-like structure and surrounded by immune cells ca

Tiny tumor model recreates cancer metastasis

by Rachel Harrison,New York UniversityClusters of about a hundred tumor cells labeled with red fluorescence were grown inside a transparent jelly-like structure and surrounded by immune cells ca
Graph filtration learning reveals new dimensions in hepatocellular carcinoma imaging

Graph filtration learning reveals new dimensions in hepatocellular carcinoma imaging

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial was published inOncotarget, titled "Beyond pixels: Graph filtration learning unveils new dimensions in hepatocellular

Graph filtration learning reveals new dimensions in hepatocellular carcinoma imaging

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new editorial was published inOncotarget, titled "Beyond pixels: Graph filtration learning unveils new dimensions in hepatocellular