Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on: March 30,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on:March 30,2024

Drugmaker GSK says EU to review womb cancer treatment

Credit: Unsplash/CC0 Public DomainBritish pharmaceutical giant GSK said on Tuesday that the EU's drug watchdog will study a new treatment for a common type of womb cancer for potential approval in

Updated on: January 30,2024

Drugmaker GSK says EU to review womb cancer treatment

Credit: Unsplash/CC0 Public DomainBritish pharmaceutical giant GSK said on Tuesday that the EU's drug watchdog will study a new treatment for a common type of womb cancer for potential approval in

Updated on:January 30,2024

Researchers map genetic signature of precursor to liver cancer

by Curtin UniversityProfessor Nina Tirnitz-Parker and Dr. Rodrigo Carlessi, from Curtin University. Credit: Curtin UniversityResearchers at Curtin University have identified the genetic signature

Updated on: February 24,2024

Researchers map genetic signature of precursor to liver cancer

by Curtin UniversityProfessor Nina Tirnitz-Parker and Dr. Rodrigo Carlessi, from Curtin University. Credit: Curtin UniversityResearchers at Curtin University have identified the genetic signature

Updated on:February 24,2024

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce

Updated on: January 02,2024

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce

Updated on:January 02,2024

Novel immune inhibitor associated with glioma progression

by Melissa Rohman,Northwestern UniversityCAFs are enriched in pediatric HGG relative to LGG and NB. (A) UMAP clustering from 21 pediatric brain samples . (B) The frequency of CAFs is a function

Updated on: March 30,2024

Novel immune inhibitor associated with glioma progression

by Melissa Rohman,Northwestern UniversityCAFs are enriched in pediatric HGG relative to LGG and NB. (A) UMAP clustering from 21 pediatric brain samples . (B) The frequency of CAFs is a function

Updated on:March 30,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on: March 08,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on:March 08,2024

Researchers discover a new mechanism of cancer immune defense

by Universitätsmedizin MagdeburgGraphical summary of inflammatory cell death induction of MHC-deficient and IFN-unresponsive tumors by CD4+ T cells in cooperation with iNOS-expressing myeloid cells. C

Updated on: February 01,2024

Researchers discover a new mechanism of cancer immune defense

by Universitätsmedizin MagdeburgGraphical summary of inflammatory cell death induction of MHC-deficient and IFN-unresponsive tumors by CD4+ T cells in cooperation with iNOS-expressing myeloid cells. C

Updated on:February 01,2024

New study suggests way to predict outcomes with high accuracy prior to surgery for pancreatic cancer patients

by National Comprehensive Cancer NetworkPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteNew research in the September 2022 issue of&nbsp

Updated on: January 13,2024

New study suggests way to predict outcomes with high accuracy prior to surgery for pancreatic cancer patients

by National Comprehensive Cancer NetworkPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteNew research in the September 2022 issue of&nbsp

Updated on:January 13,2024

Researchers define mechanism that causes kidney cancer to recur

by University of Texas Health Science Center at San AntonioNew research from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) and U.S. Department of Veterans A

Updated on: June 08,2024

Researchers define mechanism that causes kidney cancer to recur

by University of Texas Health Science Center at San AntonioNew research from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) and U.S. Department of Veterans A

Updated on:June 08,2024

Treatment strategy for locally advanced liver cancer via novel tri-modality therapy

byThe University of Hong KongCredit: Pixabay/CC0 Public DomainA pioneering phase II clinical study on tri-modality therapy (START-FIT), conducted by the Department of Surgery and Department of C

Updated on: January 15,2024

Treatment strategy for locally advanced liver cancer via novel tri-modality therapy

byThe University of Hong KongCredit: Pixabay/CC0 Public DomainA pioneering phase II clinical study on tri-modality therapy (START-FIT), conducted by the Department of Surgery and Department of C

Updated on:January 15,2024

Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced HCC patients

by Impact Journals LLCOverall survival- log rank test was used; fifteen of the 19 GH-high patients died, the median OS was 9.26 months (95% CI: 7.59, 14.59). Credit: 2022 Mohamed et al.A new research

Updated on: January 15,2024

Plasma growth hormone is a potential biomarker of response to atezolizumab and bevacizumab in advanced HCC patients

by Impact Journals LLCOverall survival- log rank test was used; fifteen of the 19 GH-high patients died, the median OS was 9.26 months (95% CI: 7.59, 14.59). Credit: 2022 Mohamed et al.A new research

Updated on:January 15,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on: April 07,2024

Tumor suppressor gene variants identified as cancer 'double whammy' for leukemia patients

by St. Jude Children's Research HospitalJun J. Yang, Ph.D., identified 22 high-risk germline variations associated with high-risk acute lymphoblastic leukemia that increases risk of relapse o

Updated on:April 07,2024