Researchers discover a new mechanism of cancer immune defense

by Universitätsmedizin MagdeburgGraphical summary of inflammatory cell death induction of MHC-deficient and IFN-unresponsive tumors by CD4+ T cells in cooperation with iNOS-expressing myeloid cells. C

Updated on: February 01,2024

Researchers discover a new mechanism of cancer immune defense

by Universitätsmedizin MagdeburgGraphical summary of inflammatory cell death induction of MHC-deficient and IFN-unresponsive tumors by CD4+ T cells in cooperation with iNOS-expressing myeloid cells. C

Updated on:February 01,2024

Researchers to test novel drug combination against toughest breast cancers

by University of California - San DiegoThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: National Ins

Updated on: June 15,2024

Researchers to test novel drug combination against toughest breast cancers

by University of California - San DiegoThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: National Ins

Updated on:June 15,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024

Novel prognostic index to predict survival outcomes in gastric cancer patients

by Impact Journals LLCCancer-specific survival curve based on the inflammation-based prognostic index. Abbreviation: ICPI: inflammation based prognostic index. Credit:Oncotarget(2023). DOI

Updated on: January 30,2024

Novel prognostic index to predict survival outcomes in gastric cancer patients

by Impact Journals LLCCancer-specific survival curve based on the inflammation-based prognostic index. Abbreviation: ICPI: inflammation based prognostic index. Credit:Oncotarget(2023). DOI

Updated on:January 30,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on: June 06,2024

Cell lines deserve unique considerations when creating research protections, researchers say

by University of MichiganCredit: CC0 Public DomainNew rules recently went into effect, seeking to protect patients who donate tissue samples for research in the age of genetic sequencing. But thi

Updated on:June 06,2024

Pancreatic cancer's addiction could be its end

by Cold Spring Harbor LaboratoryThe researchers looked for various indicators of tumor activity in normal pancreas cells (top row) comparing results to those from when the production of the P63 p

Updated on: May 13,2024

Pancreatic cancer's addiction could be its end

by Cold Spring Harbor LaboratoryThe researchers looked for various indicators of tumor activity in normal pancreas cells (top row) comparing results to those from when the production of the P63 p

Updated on:May 13,2024

Experts boost activity of potential therapeutic target in triple-negative breast cancer

by Diana Yates,University of Illinois at Urbana-ChampaignCredit: Unsplash/CC0 Public DomainLess than 20% of diagnosed breast cancers are designated "triple-negative," lacking three typ

Updated on: January 22,2024

Experts boost activity of potential therapeutic target in triple-negative breast cancer

by Diana Yates,University of Illinois at Urbana-ChampaignCredit: Unsplash/CC0 Public DomainLess than 20% of diagnosed breast cancers are designated "triple-negative," lacking three typ

Updated on:January 22,2024

Occupational health study links air pollution and cancer

by University of StirlingCredit: CC0 Public DomainUniversity of Stirling experts have discovered new evidence of the link between air pollution and cancer as part of a new occupational health stu

Updated on: April 10,2024

Occupational health study links air pollution and cancer

by University of StirlingCredit: CC0 Public DomainUniversity of Stirling experts have discovered new evidence of the link between air pollution and cancer as part of a new occupational health stu

Updated on:April 10,2024

A code for reprogramming immune sentinels

by Lund UniversityArtistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Credit: National Institutes of Health (NI

Updated on: May 23,2024

A code for reprogramming immune sentinels

by Lund UniversityArtistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Credit: National Institutes of Health (NI

Updated on:May 23,2024

Bolstering fat cells offers potential new leukemia treatment

by McMaster UniversityFat cells (white circles) in healthy human bone marrow, left, compared to bone marrow in a patient with leukemia, right. Credit: McMaster UniversityKilling cancer cells indi

Updated on: April 14,2024

Bolstering fat cells offers potential new leukemia treatment

by McMaster UniversityFat cells (white circles) in healthy human bone marrow, left, compared to bone marrow in a patient with leukemia, right. Credit: McMaster UniversityKilling cancer cells indi

Updated on:April 14,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on: March 30,2024

Research points to an immunotherapy to overcome resistant leukemia

by University of ZurichTP53 deficiency in AML leads to resistance against CAR T-cell-mediated killing that can be overcome by targeting the mevalonate and Wnt pathways. Credit:EMBO Molecula

Updated on:March 30,2024

In breast-cancer prevention, race matters

by The Ohio State UniversityCredit: CC0 Public DomainAfrican-American women at high risk of breast cancer are less likely than white women to pursue potentially life-saving preventive care, and r

Updated on: April 22,2024

In breast-cancer prevention, race matters

by The Ohio State UniversityCredit: CC0 Public DomainAfrican-American women at high risk of breast cancer are less likely than white women to pursue potentially life-saving preventive care, and r

Updated on:April 22,2024