Treatment strategy for locally advanced liver cancer via novel tri-modality therapy

byThe University of Hong KongCredit: Pixabay/CC0 Public DomainA pioneering phase II clinical study on tri-modality therapy (START-FIT), conducted by the Department of Surgery and Department of C

Updated on: January 15,2024

Treatment strategy for locally advanced liver cancer via novel tri-modality therapy

byThe University of Hong KongCredit: Pixabay/CC0 Public DomainA pioneering phase II clinical study on tri-modality therapy (START-FIT), conducted by the Department of Surgery and Department of C

Updated on:January 15,2024

Experts boost activity of potential therapeutic target in triple-negative breast cancer

by Diana Yates,University of Illinois at Urbana-ChampaignCredit: Unsplash/CC0 Public DomainLess than 20% of diagnosed breast cancers are designated "triple-negative," lacking three typ

Updated on: January 22,2024

Experts boost activity of potential therapeutic target in triple-negative breast cancer

by Diana Yates,University of Illinois at Urbana-ChampaignCredit: Unsplash/CC0 Public DomainLess than 20% of diagnosed breast cancers are designated "triple-negative," lacking three typ

Updated on:January 22,2024

Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Updated on: April 18,2024

Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Updated on:April 18,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024

Researchers take new AI approach to analyzing tumors

by Karolinska InstitutetIdeas from community ecology can complement clustering-based approaches in interpreting multiplex histology data.a–cClustering can identify the cellular and ph

Updated on: June 24,2024

Researchers take new AI approach to analyzing tumors

by Karolinska InstitutetIdeas from community ecology can complement clustering-based approaches in interpreting multiplex histology data.a–cClustering can identify the cellular and ph

Updated on:June 24,2024

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to

Updated on: January 02,2024

Prostate tumor biology may be influenced by genetic ancestry

byAmerican Association for Cancer ResearchSample collection sites and genetic admixture analysis. A, At clinical sites across Nigeria, 45 samples were collected. B, Admixture v1.3.0 was used to

Updated on:January 02,2024

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of

Updated on: March 30,2024

The search to discover why 'outliers' survive deadliest cancers

by Isabelle TOURNÉThe biotech start-up Cure51 is working on the first global molecular database of exceptional survivors of cancer.When Herve found out he had glioblastoma—the most aggressive form of

Updated on:March 30,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on: March 08,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on:March 08,2024

Study identifies new gene that drives colon cancer

by The Mount Sinai HospitalRecurrently dysregulated super-enhancers in CRC patients.aStudy overview. Figure adapted from SMART Servier Medical Art, reproduced with permission, license

Updated on: February 18,2024

Study identifies new gene that drives colon cancer

by The Mount Sinai HospitalRecurrently dysregulated super-enhancers in CRC patients.aStudy overview. Figure adapted from SMART Servier Medical Art, reproduced with permission, license

Updated on:February 18,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on: June 15,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on:June 15,2024

Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on: July 02,2024

Research reveals functional targets of oncogenic HOXA9 protein in high-risk pediatric leukemia

by St. Jude Children's Research HospitalSchematic diagram summarizing this study. Our work interrogated the transcription factor function of HOXA9 in MLL-r leukemias by targeting HOXA9-bound

Updated on:July 02,2024

Treatment beneficial for nonagenarians with lung cancer

(HealthDay)—Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a st

Updated on: April 10,2024

Treatment beneficial for nonagenarians with lung cancer

(HealthDay)—Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a st

Updated on:April 10,2024