Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on: May 23,2024

Two for the price of one: Mechanistic insights lead to drug repositioning

by University of TsukubaMolecular mechanism at a glance. SFN binds with SKP1 to sequester it in cytoplasm,resulting in the obstruction of SCFFBW7 598 complex formation. Oncoproteins including cyc

Updated on:May 23,2024

New research shows unmet support needs can lead to worse clinical outcomes

by Sylvester Comprehensive Cancer CenterCredit: CC0 Public DomainCancer patients with unmet supportive care needs are more likely to experience worse clinical outcomes, including more emergency depart

Updated on: January 12,2024

New research shows unmet support needs can lead to worse clinical outcomes

by Sylvester Comprehensive Cancer CenterCredit: CC0 Public DomainCancer patients with unmet supportive care needs are more likely to experience worse clinical outcomes, including more emergency depart

Updated on:January 12,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on: March 08,2024

Study suggests tumor mutational load may be useful metric to predict response to checkpoint-inhibitor immunotherapy

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA large team of researchers affiliated with Sloan Kettering Cancer Center, Weill Cornell Medical Center and Columbia University Medical Center has

Updated on:March 08,2024

Researchers identify enzyme that suppresses immune system in breast cancer

by Duke University Medical CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by T

Updated on: June 04,2024

Researchers identify enzyme that suppresses immune system in breast cancer

by Duke University Medical CenterThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by T

Updated on:June 04,2024

Researchers find prostate cancer drug byproduct can fuel cancer cells

by Cleveland ClinicNima Sharifi, MD, Cleveland Clinic Lerner Research Institute. Credit: Cleveland ClinicA genetic anomaly in certain men with prostate cancer may impact their response to common

Updated on: June 15,2024

Researchers find prostate cancer drug byproduct can fuel cancer cells

by Cleveland ClinicNima Sharifi, MD, Cleveland Clinic Lerner Research Institute. Credit: Cleveland ClinicA genetic anomaly in certain men with prostate cancer may impact their response to common

Updated on:June 15,2024

Research quantifies effect of chronic diseases on racial disparity in COVID-associated hospitalizations

by Louisiana State UniversityCredit: CC0 Public DomainLSU Health New Orleans conducted the first research using disease surveillance data to quantify the effect of chronic diseases on racial disp

Updated on: June 28,2024

Research quantifies effect of chronic diseases on racial disparity in COVID-associated hospitalizations

by Louisiana State UniversityCredit: CC0 Public DomainLSU Health New Orleans conducted the first research using disease surveillance data to quantify the effect of chronic diseases on racial disp

Updated on:June 28,2024

Researchers identify potential new combination treatment for pancreatic cancer

by Denise Heady,University of California, Los AngelesPancreatic cancer (the cancer cells are seen here) is the third leading cause of cancer-related deaths in the United States. Credit: Universi

Updated on: March 01,2024

Researchers identify potential new combination treatment for pancreatic cancer

by Denise Heady,University of California, Los AngelesPancreatic cancer (the cancer cells are seen here) is the third leading cause of cancer-related deaths in the United States. Credit: Universi

Updated on:March 01,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on: June 15,2024

Researchers relate amplification of chromosomal region with resistance to chemotherapeutic drug in breast cancer

by IDIBELL-Bellvitge Biomedical Research InstituteEmergence of docetaxel resistance. Credit: Eva González-SuárezResearchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the part

Updated on:June 15,2024

Researchers key to advance care planning with cancer clinical trial patients

by University of Pennsylvania School of NursingConnie M. Ulrich, PhD, RN, FAAN, the Lillian S. Brunner Chair in Medical and Surgical Nursing at the University of Pennsylvania School of Nursing (P

Updated on: June 15,2024

Researchers key to advance care planning with cancer clinical trial patients

by University of Pennsylvania School of NursingConnie M. Ulrich, PhD, RN, FAAN, the Lillian S. Brunner Chair in Medical and Surgical Nursing at the University of Pennsylvania School of Nursing (P

Updated on:June 15,2024

Virus linked to cancer takes over 'cellular mail' to alter tumor environment

by University of North Carolina at Chapel Hill School of MedicineRyan P. McNamara, PhD, is a postdoctoral research associate at UNC Lineberger. Credit: University of North Carolina at Chapel Hill

Updated on: May 07,2024

Virus linked to cancer takes over 'cellular mail' to alter tumor environment

by University of North Carolina at Chapel Hill School of MedicineRyan P. McNamara, PhD, is a postdoctoral research associate at UNC Lineberger. Credit: University of North Carolina at Chapel Hill

Updated on:May 07,2024

When should NHS contact patients over faulty genes?

by University of ExeterCredit: CC0 Public DomainThe NHS and health services worldwide need to develop policies on when patients should be "re-contacted" about faulty genes, as the curre

Updated on: May 11,2024

When should NHS contact patients over faulty genes?

by University of ExeterCredit: CC0 Public DomainThe NHS and health services worldwide need to develop policies on when patients should be "re-contacted" about faulty genes, as the curre

Updated on:May 11,2024

Researchers convert pro-tumor macrophages into cancer killers

by University of California - San DiegoCredit: CC0 Public DomainEpithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer ther

Updated on: June 15,2024

Researchers convert pro-tumor macrophages into cancer killers

by University of California - San DiegoCredit: CC0 Public DomainEpithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer ther

Updated on:June 15,2024