Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on: September 28,2024 0

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on:September 28,2024 0

Post-Transplant Cyclophosphamide-Based GVHD Prophylaxis Bests Standard Regimen in Phase III Study

October 2023Katie RobinsonPatients undergoing a human leukocyte antigen (HLA)-matched allogeneic hematopoietic cell transplantation (alloHCT) with reduced-intensity conditioning who received a prophyl

Updated on: February 18,2024 12

Post-Transplant Cyclophosphamide-Based GVHD Prophylaxis Bests Standard Regimen in Phase III Study

October 2023Katie RobinsonPatients undergoing a human leukocyte antigen (HLA)-matched allogeneic hematopoietic cell transplantation (alloHCT) with reduced-intensity conditioning who received a prophyl

Updated on:February 18,2024 12

Mini-colons advance colorectal cancer research

byEcole Polytechnique Federale de LausanneCredit: L. Francisco Lorenzo-Martín (EPFL)In a breakthrough for cancer research, scientists at EPFL have created lab-grown mini-colons that can accurate

Updated on: April 28,2024 0

Mini-colons advance colorectal cancer research

byEcole Polytechnique Federale de LausanneCredit: L. Francisco Lorenzo-Martín (EPFL)In a breakthrough for cancer research, scientists at EPFL have created lab-grown mini-colons that can accurate

Updated on:April 28,2024 0

Erectile dysfunction drugs and flu vaccine may work together to help immune system fight cancer after surgery

by The Ottawa HospitalNew research shows that erectile dysfunction drugs and flu vaccine may work together to help the immune system fight cancer after surgery. Credit: The Ottawa HospitalA new study

Updated on: April 10,2024 19

Erectile dysfunction drugs and flu vaccine may work together to help immune system fight cancer after surgery

by The Ottawa HospitalNew research shows that erectile dysfunction drugs and flu vaccine may work together to help the immune system fight cancer after surgery. Credit: The Ottawa HospitalA new study

Updated on:April 10,2024 19

Unique approach to treatment of rare and aggressive blood cancers

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainA unique approach to targeting the abnormal T-cells that cause T-cell lymphomas could offer hope to patients with the aggressive and dif

Updated on: April 10,2024 15

Unique approach to treatment of rare and aggressive blood cancers

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainA unique approach to targeting the abnormal T-cells that cause T-cell lymphomas could offer hope to patients with the aggressive and dif

Updated on:April 10,2024 15

Gray hair and wrinkles at an early age lead researchers to potential new treatment for rare cancer

by University of CopenhagenSchematic representation of the PandaOmics application for a rapid biomarker discovery and target characterization in cancer. Gene expression signatures have been exami

Updated on: February 18,2024 17

Gray hair and wrinkles at an early age lead researchers to potential new treatment for rare cancer

by University of CopenhagenSchematic representation of the PandaOmics application for a rapid biomarker discovery and target characterization in cancer. Gene expression signatures have been exami

Updated on:February 18,2024 17

Molecular change to immunotherapy antibody could accelerate immune response to cancer

byWeizmann Institute of ScienceTissue sample of a particularly aggressive skin cancer reveals immune cells (yellow) that express on their surfaces a “brake pedal” receptor called FcgIIb (purple)

Updated on: January 02,2024 9

Molecular change to immunotherapy antibody could accelerate immune response to cancer

byWeizmann Institute of ScienceTissue sample of a particularly aggressive skin cancer reveals immune cells (yellow) that express on their surfaces a “brake pedal” receptor called FcgIIb (purple)

Updated on:January 02,2024 9

Inherited mutations may play a role in pancreatic cancer development

by Johns Hopkins University School of MedicineAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA small, retrospective study has found tha

Updated on: May 13,2024 4

Inherited mutations may play a role in pancreatic cancer development

by Johns Hopkins University School of MedicineAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA small, retrospective study has found tha

Updated on:May 13,2024 4

Sticky cell fingers help keep breast tumors contained

by University of TurkuBreast cancer cells break through the basement membrane acting as a biological barrier. In the image, the finger-like projections formed by the actin of cancer cells invadin

Updated on: February 24,2024 10

Sticky cell fingers help keep breast tumors contained

by University of TurkuBreast cancer cells break through the basement membrane acting as a biological barrier. In the image, the finger-like projections formed by the actin of cancer cells invadin

Updated on:February 24,2024 10

Genetic breast cancer study alters guidelines in Sweden

by Lund UniversityCredit: Pixabay/CC0 Public DomainBRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. Howev

Updated on: February 01,2024 14

Genetic breast cancer study alters guidelines in Sweden

by Lund UniversityCredit: Pixabay/CC0 Public DomainBRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. Howev

Updated on:February 01,2024 14

Allogeneic hematopoietic cell transplant outcomes improved from 2005 to 2019: Study

by Lori SolomonOutcomes of allogeneic hematopoietic cell transplantation (allo-HCT) in patients with acute myeloid leukemia (AML) and second complete remission (CR2) have significantly improved over t

Updated on: February 18,2024 17

Allogeneic hematopoietic cell transplant outcomes improved from 2005 to 2019: Study

by Lori SolomonOutcomes of allogeneic hematopoietic cell transplantation (allo-HCT) in patients with acute myeloid leukemia (AML) and second complete remission (CR2) have significantly improved over t

Updated on:February 18,2024 17

Newly discovered link between FBXW7 mutations and EGFR signaling in colorectal cancer

by Hubrecht InstituteTwo microscopy images of human colon organoids. The left image shows an organoid with the FBXW7 mutation (colorectal cancer), and the right image shows an organoid without th

Updated on: March 30,2024 0

Newly discovered link between FBXW7 mutations and EGFR signaling in colorectal cancer

by Hubrecht InstituteTwo microscopy images of human colon organoids. The left image shows an organoid with the FBXW7 mutation (colorectal cancer), and the right image shows an organoid without th

Updated on:March 30,2024 0