Study offers way to increase immune checkpoint inhibitor effectiveness in patients with MTAP-deleted cancers

by Dana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.09.005Loss of the "housekeeping" gene methylthioadenosine phosphorylas

Updated on: February 01,2024

Study offers way to increase immune checkpoint inhibitor effectiveness in patients with MTAP-deleted cancers

by Dana-Farber Cancer InstituteGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.09.005Loss of the "housekeeping" gene methylthioadenosine phosphorylas

Updated on:February 01,2024

Cis-regulatory sequences indicative of nasopharyngeal carcinoma risk identified

by Justin Jackson , Medical XpressCredit:The American Journal of Human Genetics(2023). DOI: 10.1016/j.ajhg.2023.06.003Research led by the Sun Yat-sen University Cancer Center in China has

Updated on: February 01,2024

Cis-regulatory sequences indicative of nasopharyngeal carcinoma risk identified

by Justin Jackson , Medical XpressCredit:The American Journal of Human Genetics(2023). DOI: 10.1016/j.ajhg.2023.06.003Research led by the Sun Yat-sen University Cancer Center in China has

Updated on:February 01,2024

Fatty liver is increasingly the cause of liver cell cancer

by Stefan Zorn, Medizinische Hochschule HannoverCredit: Pixabay/CC0 Public DomainHepatocellular carcinoma (HCC) is one of the most common cancers worldwide. In Germany, there are currently around 9,00

Updated on: January 29,2024

Fatty liver is increasingly the cause of liver cell cancer

by Stefan Zorn, Medizinische Hochschule HannoverCredit: Pixabay/CC0 Public DomainHepatocellular carcinoma (HCC) is one of the most common cancers worldwide. In Germany, there are currently around 9,00

Updated on:January 29,2024

Study shows benefit of universal genetic testing after breast cancer diagnosis

byWalter and Eliza Hall Institute of Medical ResearchClassification of 31 participants found to carry pathogenic gene variants, by gene, estimated risk of having a pathogenic gene variant,* and

Updated on: January 29,2024

Study shows benefit of universal genetic testing after breast cancer diagnosis

byWalter and Eliza Hall Institute of Medical ResearchClassification of 31 participants found to carry pathogenic gene variants, by gene, estimated risk of having a pathogenic gene variant,* and

Updated on:January 29,2024

Researchers develop new one-two punch against melanoma in mouse model

by Johns Hopkins University School of MedicineCredit: Kimmel Cancer CenterResearchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins and the Johns Hopkins University

Updated on: June 04,2024

Researchers develop new one-two punch against melanoma in mouse model

by Johns Hopkins University School of MedicineCredit: Kimmel Cancer CenterResearchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at Johns Hopkins and the Johns Hopkins University

Updated on:June 04,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on: February 18,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on:February 18,2024

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper

Updated on: January 11,2024

Novel therapeutic strategy against melanoma: Combined targeting of hedgehog signaling and BRD4

by Impact Journals LLCCombined targeting of SMO and BRD4 as a potential therapeutic strategy against melanoma. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28441A new editorial paper

Updated on:January 11,2024

Experts advise against routine testing for prostate cancer

by British Medical JournalMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0Routine testing for prostate cancer is n

Updated on: April 07,2024

Experts advise against routine testing for prostate cancer

by British Medical JournalMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0Routine testing for prostate cancer is n

Updated on:April 07,2024

A deep-learning model may help predict lung cancer survival and outcomes

by American Association for Cancer ResearchLung CA seen on CXR. Credit:CC BY-SA 4.0James Heilman, MD/WikipediaA deep-learning model developed using serial image scans of tumors from p

Updated on: May 20,2024

A deep-learning model may help predict lung cancer survival and outcomes

by American Association for Cancer ResearchLung CA seen on CXR. Credit:CC BY-SA 4.0James Heilman, MD/WikipediaA deep-learning model developed using serial image scans of tumors from p

Updated on:May 20,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on: April 01,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on:April 01,2024

Study overturns dogma of cancer metabolism theory

by University of California, Los AngelesImage shows squamous cell skin cancer tumors with lactate production (a byproduct of glucose consumption) in purple. The tumor with lactate production bloc

Updated on: June 01,2024

Study overturns dogma of cancer metabolism theory

by University of California, Los AngelesImage shows squamous cell skin cancer tumors with lactate production (a byproduct of glucose consumption) in purple. The tumor with lactate production bloc

Updated on:June 01,2024

Cancer in Europe: more cases but fewer deaths

Credit: CC0 Public DomainThe number of cancer cases has continued to rise across Europe, however mortality rates from the disease have fallen, according to the World Health Organization's "Eu

Updated on: March 06,2024

Cancer in Europe: more cases but fewer deaths

Credit: CC0 Public DomainThe number of cancer cases has continued to rise across Europe, however mortality rates from the disease have fallen, according to the World Health Organization's "Eu

Updated on:March 06,2024