Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on: June 08,2024

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on:June 08,2024

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Updated on: April 07,2024

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Updated on:April 07,2024

Hypnosis may help reduce distress of cancer treatment in children

by University of ExeterHypnosis may help reduce the distress of cancer treatment in children. Credit: University of ExeterHypnosis could help to reduce the fear of medical procedures in children

Updated on: March 01,2024

Hypnosis may help reduce distress of cancer treatment in children

by University of ExeterHypnosis may help reduce the distress of cancer treatment in children. Credit: University of ExeterHypnosis could help to reduce the fear of medical procedures in children

Updated on:March 01,2024

Experts advise against routine testing for prostate cancer

by British Medical JournalMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0Routine testing for prostate cancer is n

Updated on: April 07,2024

Experts advise against routine testing for prostate cancer

by British Medical JournalMicrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia,CC BY-SA 3.0Routine testing for prostate cancer is n

Updated on:April 07,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on: April 01,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on:April 01,2024

A new therapeutic strategy to improve treatment of aggressive endometrial cancer

by Autonomous University of BarcelonaERK5 inhibition impairs EC cell proliferation.AGenomic profiles of components of the MEK5-ERK5 pathway in EC patients obtained from Uterine Corpus

Updated on: February 23,2024

A new therapeutic strategy to improve treatment of aggressive endometrial cancer

by Autonomous University of BarcelonaERK5 inhibition impairs EC cell proliferation.AGenomic profiles of components of the MEK5-ERK5 pathway in EC patients obtained from Uterine Corpus

Updated on:February 23,2024

The sugar-attaching enzyme that defines colon cancer

by American Society for Biochemistry and Molecular BiologyThe enzyme GalNAc-T6 is selectively up-regulated in colon adenocarcinomas, and its expression is associated with a cancer-like growth pat

Updated on: April 14,2024

The sugar-attaching enzyme that defines colon cancer

by American Society for Biochemistry and Molecular BiologyThe enzyme GalNAc-T6 is selectively up-regulated in colon adenocarcinomas, and its expression is associated with a cancer-like growth pat

Updated on:April 14,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on: January 02,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on:January 02,2024

New insights into sarcoma open novel avenues of study

by Karolinska InstitutetCredit: CC0 Public DomainUndifferentiated uterine sarcoma is a very rare but extremely aggressive cancer type. It can be divided into four groups with different characteri

Updated on: March 06,2024

New insights into sarcoma open novel avenues of study

by Karolinska InstitutetCredit: CC0 Public DomainUndifferentiated uterine sarcoma is a very rare but extremely aggressive cancer type. It can be divided into four groups with different characteri

Updated on:March 06,2024

New bioinformatics tool to identify chromosomal alterations in tumor cells

by University of BarcelonaRepresentative output image generated by QATS in which two toroidal nuclei (in magenta) and four micronuclei (in green) were identified. Credit:Bioinformatics&nbsp

Updated on: March 30,2024

New bioinformatics tool to identify chromosomal alterations in tumor cells

by University of BarcelonaRepresentative output image generated by QATS in which two toroidal nuclei (in magenta) and four micronuclei (in green) were identified. Credit:Bioinformatics&nbsp

Updated on:March 30,2024

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Updated on: January 12,2024

Novel bioassay predicts cancer patients' response to immunotherapy

byBen-Gurion University of the NegevIcAR response to fresh and fixed PDXs and generation of an IcAR score.(A) Schematic representation of the IcAR assay protocol. Following flow cytometry determ

Updated on:January 12,2024

Dietary factors affecting gut microbiome may influence response to immunotherapy in melanoma patients

by American Association for Cancer ResearchCredit: CC0 Public DomainAmong melanoma patients treated with anti-PD-1 immunotherapy, consumption of a high-fiber diet was associated with higher gut m

Updated on: May 11,2024

Dietary factors affecting gut microbiome may influence response to immunotherapy in melanoma patients

by American Association for Cancer ResearchCredit: CC0 Public DomainAmong melanoma patients treated with anti-PD-1 immunotherapy, consumption of a high-fiber diet was associated with higher gut m

Updated on:May 11,2024