Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on: April 28,2024

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on:April 28,2024

Study illuminates precancerous 'clonal outgrowth' in blood cells

byWeill Cornell Medical CollegeCredit: CC0 Public DomainA common, spontaneous mutation in blood stem cells, which has been linked to higher risks of blood cancer and cardiovascular disease, may

Updated on: January 22,2024

Study illuminates precancerous 'clonal outgrowth' in blood cells

byWeill Cornell Medical CollegeCredit: CC0 Public DomainA common, spontaneous mutation in blood stem cells, which has been linked to higher risks of blood cancer and cardiovascular disease, may

Updated on:January 22,2024

Researchers identify a test to target cancer drug

by University of LeedsKiller T cells surround a cancer cell. Credit: NIHDoctors are developing a more personalised approach to the treatment of bowel cancer, thanks to research which has found a

Updated on: June 06,2024

Researchers identify a test to target cancer drug

by University of LeedsKiller T cells surround a cancer cell. Credit: NIHDoctors are developing a more personalised approach to the treatment of bowel cancer, thanks to research which has found a

Updated on:June 06,2024

Technique that characterizes different immune cell groups in individual patients could revolutionize cancer treatments

by Agency for Science, Technology and Research (A*STAR), SingaporeA plot of all the different possible phenotypes of T cells before without (left) vs. with (right) immune checkpoint blockade immu

Updated on: March 01,2024

Technique that characterizes different immune cell groups in individual patients could revolutionize cancer treatments

by Agency for Science, Technology and Research (A*STAR), SingaporeA plot of all the different possible phenotypes of T cells before without (left) vs. with (right) immune checkpoint blockade immu

Updated on:March 01,2024

Salmonella research unlocks the potential of bacteria to treat bowel cancer

byUniversity of GlasgowTILs from mice treated with Salmonella are functionally defective. Credit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-024-00159-2Fighting bowel cancer w

Updated on: December 01,2024

Salmonella research unlocks the potential of bacteria to treat bowel cancer

byUniversity of GlasgowTILs from mice treated with Salmonella are functionally defective. Credit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-024-00159-2Fighting bowel cancer w

Updated on:December 01,2024

Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an accepta

Updated on: September 27,2024

Telisotuzumab vedotin shows durable response in some Asian patients with nonsquamous NSCLC

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an accepta

Updated on:September 27,2024

Reversing chemotherapy resistance in pancreatic cancer

byStanford UniversityCredit: CC0 Public DomainPancreatic cancer is a particularly aggressive and difficult-to-treat cancer, in part because it is often resistant to chemotherapy. Now, researcher

Updated on: July 05,2024

Reversing chemotherapy resistance in pancreatic cancer

byStanford UniversityCredit: CC0 Public DomainPancreatic cancer is a particularly aggressive and difficult-to-treat cancer, in part because it is often resistant to chemotherapy. Now, researcher

Updated on:July 05,2024

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on: May 21,2024

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on:May 21,2024

Researchers share insights on the evolution of proton radiotherapy

by Mass General BrighamCredit: Unsplash/CC0 Public DomainIn a review article published inThe Lancet Oncology, Susu Yan, Ph.D., and Thomas Bortfeld, Ph.D., from the Biophysics Division of MG

Updated on: February 01,2024

Researchers share insights on the evolution of proton radiotherapy

by Mass General BrighamCredit: Unsplash/CC0 Public DomainIn a review article published inThe Lancet Oncology, Susu Yan, Ph.D., and Thomas Bortfeld, Ph.D., from the Biophysics Division of MG

Updated on:February 01,2024

Tumor-specific therapy targets ovarian cancer

by Anna Zarra Aldrich,University of ConnecticutUConn professor Xiuling Lu with members of her lab team at the School of Pharmacy on Nov. 8, 2018. Credit: (Sean Flynn/UConn Photo)Nami Therapeutic

Updated on: April 09,2024

Tumor-specific therapy targets ovarian cancer

by Anna Zarra Aldrich,University of ConnecticutUConn professor Xiuling Lu with members of her lab team at the School of Pharmacy on Nov. 8, 2018. Credit: (Sean Flynn/UConn Photo)Nami Therapeutic

Updated on:April 09,2024

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Updated on: April 09,2024

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Updated on:April 09,2024

Researchers to develop handheld device to diagnose skin cancer

by Stevens Institute of TechnologyStevens researchers develop a technique based on reflectivity patterns that can distinguish multiple forms of skin cancer, including basal cell carcinoma (left)

Updated on: June 15,2024

Researchers to develop handheld device to diagnose skin cancer

by Stevens Institute of TechnologyStevens researchers develop a technique based on reflectivity patterns that can distinguish multiple forms of skin cancer, including basal cell carcinoma (left)

Updated on:June 15,2024