Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on: April 28,2024

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on:April 28,2024

Study shows immunotherapy may benefit a subset of patients with penile cancer

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainPenile cancer is a rare disease with approximately 2,070 new cases each year in the U.S. Treatment options are limited and typical

Updated on: January 22,2024

Study shows immunotherapy may benefit a subset of patients with penile cancer

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainPenile cancer is a rare disease with approximately 2,070 new cases each year in the U.S. Treatment options are limited and typical

Updated on:January 22,2024

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

Updated on: March 14,2024

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

Updated on:March 14,2024

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Updated on: February 24,2024

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Updated on:February 24,2024

HPV vaccine eliminates advanced skin cancer in 97-year-old

(HealthDay)—The 9-valent human papillomavirus (HPV) vaccine could be a therapeutic option for patients with cutaneous squamous cell carcinoma when surgical management is not an option, according to a

Updated on: March 12,2024

HPV vaccine eliminates advanced skin cancer in 97-year-old

(HealthDay)—The 9-valent human papillomavirus (HPV) vaccine could be a therapeutic option for patients with cutaneous squamous cell carcinoma when surgical management is not an option, according to a

Updated on:March 12,2024

First-line regimens with endocrine therapy show benefits in breast cancer

by Lori SolomonFirst-line regimens with endocrine therapy (ET) may be associated with benefits among patients with human epidermal growth factor receptor 2-positive (ERBB2-positive [formerly HER2-posi

Updated on: February 03,2024

First-line regimens with endocrine therapy show benefits in breast cancer

by Lori SolomonFirst-line regimens with endocrine therapy (ET) may be associated with benefits among patients with human epidermal growth factor receptor 2-positive (ERBB2-positive [formerly HER2-posi

Updated on:February 03,2024

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that

Updated on: February 03,2024

Team discovers broken 'brake' of cancer mutation machine

by UT Southwestern Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.06.010Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that

Updated on:February 03,2024

Moderate delays safe in treating colon cancer

by Paul Mayne,University of Western OntarioSchulich School of Medicine & Dentistry medical resident Dr. Kerollos Wanis, left, assists Drs. David Bottoni and Robert Black with a cancer-resect

Updated on: April 09,2024

Moderate delays safe in treating colon cancer

by Paul Mayne,University of Western OntarioSchulich School of Medicine & Dentistry medical resident Dr. Kerollos Wanis, left, assists Drs. David Bottoni and Robert Black with a cancer-resect

Updated on:April 09,2024

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Updated on: April 09,2024

Cancer genes' age and function strongly influence their mutational status

by eLifeCredit: CC0 Public DomainResearchers have provided new insight on why some genes that formed during the evolution of the earliest animals on earth are particularly impaired (or dysregulat

Updated on:April 09,2024

Delaying antibiotics for neutropenic fever may not affect survival of cancer inpatients

byWolters Kluwer HealthCredit: Unsplash/CC0 Public DomainIn cancer patients with neutropenic fever, delaying antibiotic treatment past 60 minutes from the time of fever detection does not reduce

Updated on: January 16,2024

Delaying antibiotics for neutropenic fever may not affect survival of cancer inpatients

byWolters Kluwer HealthCredit: Unsplash/CC0 Public DomainIn cancer patients with neutropenic fever, delaying antibiotic treatment past 60 minutes from the time of fever detection does not reduce

Updated on:January 16,2024

Second primary malignancy risk increased after cutaneous B-cell lymphoma

by Elana GotkinePatients with primary cutaneous B-cell lymphomas (PCBCLs) have an increased risk for second primary malignancies (SPMs), according to a studypublishedonline March 19 in the

Updated on: April 06,2024

Second primary malignancy risk increased after cutaneous B-cell lymphoma

by Elana GotkinePatients with primary cutaneous B-cell lymphomas (PCBCLs) have an increased risk for second primary malignancies (SPMs), according to a studypublishedonline March 19 in the

Updated on:April 06,2024

Regorafenib shown to augment antitumor effect of anti-PD-1 immunotherapy in advanced gastric cancers

byKumamoto UniversityCredit:Cancer Research(2022). DOI: 10.1158/0008-5472.CAN-22-1890Fibrotic cancers such as gastric cancers are highly resistant to conventional therapies like immu

Updated on: January 03,2024

Regorafenib shown to augment antitumor effect of anti-PD-1 immunotherapy in advanced gastric cancers

byKumamoto UniversityCredit:Cancer Research(2022). DOI: 10.1158/0008-5472.CAN-22-1890Fibrotic cancers such as gastric cancers are highly resistant to conventional therapies like immu

Updated on:January 03,2024