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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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70-gene signature impacts treatment decisions in breast CA

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud

70-gene signature impacts treatment decisions in breast CA

(HealthDay)—The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a stud
Children with resistant leukemia given CRISPR-edited T cells: Phase 1 study results reported

Children with resistant leukemia given CRISPR-edited T cells: Phase 1 study results reported

byUniversity College LondonAn artist’s depiction of a T cell. Credit: NIAIDResearchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (

Children with resistant leukemia given CRISPR-edited T cells: Phase 1 study results reported

byUniversity College LondonAn artist’s depiction of a T cell. Credit: NIAIDResearchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (
Digital rectal examination is not useful to early detect prostate cancers, says new research

Digital rectal examination is not useful to early detect prostate cancers, says new research

by European Association of UrologyCredit: Unsplash/CC0 Public DomainA common method of detecting prostate cancer may not be accurate enough as a reliable screening tool by itself, scientists have

Digital rectal examination is not useful to early detect prostate cancers, says new research

by European Association of UrologyCredit: Unsplash/CC0 Public DomainA common method of detecting prostate cancer may not be accurate enough as a reliable screening tool by itself, scientists have
Study shows why a common form of immunotherapy fails, and suggests solution

Study shows why a common form of immunotherapy fails, and suggests solution

by Georgetown University Medical CenterSamir N. Khleif, MD, director of The Loop Immuno-Oncology Laboratory at Georgetown Lombardi, led the research team that published new research on checkpoint

Study shows why a common form of immunotherapy fails, and suggests solution

by Georgetown University Medical CenterSamir N. Khleif, MD, director of The Loop Immuno-Oncology Laboratory at Georgetown Lombardi, led the research team that published new research on checkpoint
Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle
Clinical trial suggests new cell therapy for relapsed leukemia patients

Clinical trial suggests new cell therapy for relapsed leukemia patients

by Stanford University Medical CenterA Wright's stained bone marrow aspirate smear from a patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaA significant

Clinical trial suggests new cell therapy for relapsed leukemia patients

by Stanford University Medical CenterA Wright's stained bone marrow aspirate smear from a patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/WikipediaA significant
Research offers new approach to nongenetic T-cell-based immunotherapy

Research offers new approach to nongenetic T-cell-based immunotherapy

by WileyCredit: WileyImmunotherapies for cancer aim to induce the immune system to combat cancer cells more effectively. In the journalAngewandte Chemie International Edition, a Chinese res

Research offers new approach to nongenetic T-cell-based immunotherapy

by WileyCredit: WileyImmunotherapies for cancer aim to induce the immune system to combat cancer cells more effectively. In the journalAngewandte Chemie International Edition, a Chinese res
Taming overactive molecular signaling in renal cell cancer

Taming overactive molecular signaling in renal cell cancer

by Johns Hopkins University School of MedicineMurine renal tumors with Tsc2 loss have increased TFEB/TFE3 nuclear localization. Credit: Clarence Rachel Villanueva and Adrianna A. Mendes,Nat

Taming overactive molecular signaling in renal cell cancer

by Johns Hopkins University School of MedicineMurine renal tumors with Tsc2 loss have increased TFEB/TFE3 nuclear localization. Credit: Clarence Rachel Villanueva and Adrianna A. Mendes,Nat
Supporting smokers with new lung health checks could save thousands of lives

Supporting smokers with new lung health checks could save thousands of lives

by University of NottinghamCredit: Unsplash/CC0 Public DomainResearchers and national cancer charities strongly welcome the UK Government's decision to back National Screening Committee recom

Supporting smokers with new lung health checks could save thousands of lives

by University of NottinghamCredit: Unsplash/CC0 Public DomainResearchers and national cancer charities strongly welcome the UK Government's decision to back National Screening Committee recom
First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainIn patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral cris

First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainIn patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral cris
Researchers discover how malignant melanoma eludes immune cells

Researchers discover how malignant melanoma eludes immune cells

by Alan Dove,Columbia University Irving Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.05.014Malignant melanoma, a dangerous type of skin cancer, deploys an elegan

Researchers discover how malignant melanoma eludes immune cells

by Alan Dove,Columbia University Irving Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.05.014Malignant melanoma, a dangerous type of skin cancer, deploys an elegan
Research suggests a new approach for treatment-resistant breast cancers

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15

Research suggests a new approach for treatment-resistant breast cancers

by Louisiana State UniversityCB-103 shows synergy with paclitaxel and fulvestrant in breast cancer cell lines. TNBC (HCC1187) and ER+ BC (MCF-7) cells were treated with combinations of CB-103 (15