Drug bypasses suppressive immune cells to unleash immunotherapy

by Marta Wegorzewska,Washington University School of MedicineImmunobiologists Robert Schreiber, Ph.D., (left) and Hussein Sultan, Ph.D., of Washington University School of Medicine in St. Louis,

Updated on: August 28,2024

Drug bypasses suppressive immune cells to unleash immunotherapy

by Marta Wegorzewska,Washington University School of MedicineImmunobiologists Robert Schreiber, Ph.D., (left) and Hussein Sultan, Ph.D., of Washington University School of Medicine in St. Louis,

Updated on:August 28,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on: February 23,2024

An unexpected journey reveals a potent way to attack tumors

by Nancy Fliesler,Children's Hospital BostonSenescence inducer CuSO4, which causes ER stress, activates NKp46- and NKG2D-dependent NK killing, but 4-PBA, which induces senescence without ER

Updated on:February 23,2024

Japan to trial 'world's first urine test' to spot cancer

Credit: CC0 Public DomainA Japanese firm is poised to carry out what it hailed as the world's first experiment to test for cancer using urine samples, which would greatly facilitate screening for

Updated on: March 01,2024

Japan to trial 'world's first urine test' to spot cancer

Credit: CC0 Public DomainA Japanese firm is poised to carry out what it hailed as the world's first experiment to test for cancer using urine samples, which would greatly facilitate screening for

Updated on:March 01,2024

Medicare to cover CAR-T therapy for leukemia, lymphoma

A breakthrough gene therapy will be covered for certain types of lymphoma and leukemia, Medicare says.Chimeric antigen receptor T-cell (CAR-T)therapyboosts a patient's own immune cells

Updated on: May 17,2024

Medicare to cover CAR-T therapy for leukemia, lymphoma

A breakthrough gene therapy will be covered for certain types of lymphoma and leukemia, Medicare says.Chimeric antigen receptor T-cell (CAR-T)therapyboosts a patient's own immune cells

Updated on:May 17,2024

New bioinformatics tool to identify chromosomal alterations in tumor cells

by University of BarcelonaRepresentative output image generated by QATS in which two toroidal nuclei (in magenta) and four micronuclei (in green) were identified. Credit:Bioinformatics&nbsp

Updated on: March 30,2024

New bioinformatics tool to identify chromosomal alterations in tumor cells

by University of BarcelonaRepresentative output image generated by QATS in which two toroidal nuclei (in magenta) and four micronuclei (in green) were identified. Credit:Bioinformatics&nbsp

Updated on:March 30,2024

Boosting physical activity and curbing sitting time are highly likely to lower breast cancer risk

by British Medical JournalCredit: Pixabay/CC0 Public DomainBoosting physical activity levels and curbing sitting time are highly likely to lower breast cancer risk, finds research designed to str

Updated on: February 03,2024

Boosting physical activity and curbing sitting time are highly likely to lower breast cancer risk

by British Medical JournalCredit: Pixabay/CC0 Public DomainBoosting physical activity levels and curbing sitting time are highly likely to lower breast cancer risk, finds research designed to str

Updated on:February 03,2024

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on: February 01,2024

Study uncovers epigenetic source of resistance to targeted therapy in EGFR-mutant lung cancer

by Dana-Farber Cancer InstituteCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.07.005When lung cancers driven by mutations in the EGFR gene become resistant to osimertinib or othe

Updated on:February 01,2024

Drug compound could be next-generation treatment for aggressive form of leukemia

by Tom Coyne,Purdue UniversityHerman Sintim, the Drug Discovery Professor of Chemistry in Purdue University's Department of Chemistry, is leading a team of researchers developing a series of

Updated on: May 25,2024

Drug compound could be next-generation treatment for aggressive form of leukemia

by Tom Coyne,Purdue UniversityHerman Sintim, the Drug Discovery Professor of Chemistry in Purdue University's Department of Chemistry, is leading a team of researchers developing a series of

Updated on:May 25,2024

Algorithm helps doctors identify more aggressive types of basal cell carcinoma

by Elin Lindström,University of GothenburgCredit: Paul Björkman (Sahlgrenska Universitetssjukhuset)An algorithm can help health care professionals recognize which patients have a highly aggressi

Updated on: July 05,2024

Algorithm helps doctors identify more aggressive types of basal cell carcinoma

by Elin Lindström,University of GothenburgCredit: Paul Björkman (Sahlgrenska Universitetssjukhuset)An algorithm can help health care professionals recognize which patients have a highly aggressi

Updated on:July 05,2024

Long-course radiotherapy found to be better than short-course for organ preservation in rectal cancer

byEuropean Society for Medical OncologyCredit: Unsplash/CC0 Public DomainThe COVID-19 pandemic has enabled researchers to show that a long course of radiotherapy given before surgery may be a be

Updated on: September 28,2024

Long-course radiotherapy found to be better than short-course for organ preservation in rectal cancer

byEuropean Society for Medical OncologyCredit: Unsplash/CC0 Public DomainThe COVID-19 pandemic has enabled researchers to show that a long course of radiotherapy given before surgery may be a be

Updated on:September 28,2024

Breast cancer patients with higher BMI more likely to experience heart damage during chemotherapy, study finds

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainBreast cancer survival rates have improved considerably in the last few decades in Colombia, but factors that increase the likel

Updated on: January 23,2024

Breast cancer patients with higher BMI more likely to experience heart damage during chemotherapy, study finds

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainBreast cancer survival rates have improved considerably in the last few decades in Colombia, but factors that increase the likel

Updated on:January 23,2024

Tumor macrophage marker offers unique target for treatment

by National Institutes of HealthA nanoparticle attached to CRV (CRV-NP) specifically homed to macrophages in breast tumors in mice (yellow arrow) and did not home to spleen, lung or heart. Nanopa

Updated on: April 09,2024

Tumor macrophage marker offers unique target for treatment

by National Institutes of HealthA nanoparticle attached to CRV (CRV-NP) specifically homed to macrophages in breast tumors in mice (yellow arrow) and did not home to spleen, lung or heart. Nanopa

Updated on:April 09,2024