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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Study shows multiple beams, intervals in delivery decrease the skin-saving benefits of FLASH radiotherapy for cancer

Study shows multiple beams, intervals in delivery decrease the skin-saving benefits of FLASH radiotherapy for cancer

by Katie Pence,University of CincinnatiCredit: CC0 Public DomainA published study by researchers at the University of Cincinnati Cancer Center and Cincinnati Children's Hospital Medical Cent

Study shows multiple beams, intervals in delivery decrease the skin-saving benefits of FLASH radiotherapy for cancer

by Katie Pence,University of CincinnatiCredit: CC0 Public DomainA published study by researchers at the University of Cincinnati Cancer Center and Cincinnati Children's Hospital Medical Cent
Investigators find disparities in mesothelioma survival due to social determinants, limited access

Investigators find disparities in mesothelioma survival due to social determinants, limited access

by Sylvester Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainTreatment outcomes for patients with malignant pleural mesothelioma, a rare cancer commonly known as mesothelioma, are often af

Investigators find disparities in mesothelioma survival due to social determinants, limited access

by Sylvester Comprehensive Cancer CenterCredit: Pixabay/CC0 Public DomainTreatment outcomes for patients with malignant pleural mesothelioma, a rare cancer commonly known as mesothelioma, are often af
New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no

New screening tool to explore mechanisms behind cancer, autoimmunity and neurodegeneration

by Jelena Pupavac,Wellcome Trust Sanger InstituteA single-cell base editor screen tiling acrossJAK1is improved by coupling genotype with transcriptome.aUMAP of LoF and no
Researchers make next move in the fight against ovarian cancer

Researchers make next move in the fight against ovarian cancer

by University of Arizona College of EngineeringGraphic representation of falloposcope image resolution on the University of Arizona's "Block A." Credit: University of ArizonaOvarian canc

Researchers make next move in the fight against ovarian cancer

by University of Arizona College of EngineeringGraphic representation of falloposcope image resolution on the University of Arizona's "Block A." Credit: University of ArizonaOvarian canc
Researchers uncover new targets for breast cancers resistant to standard therapies

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b
Researchers characterize mechanism of action of CAR T cells

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci
Researchers identify protein that controls CAR T cell longevity

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription
Gut bacteria engineered to act as tumor GPS for immunotherapies

Gut bacteria engineered to act as tumor GPS for immunotherapies

byDana-Farber Cancer InstituteBacteria displaying hDR18 enhance anti-tumor responses of MSLN-CAR NK cells. Credit:Nature Biotechnology(2024). DOI: 10.1038/s41587-024-02418-6Immunothe

Gut bacteria engineered to act as tumor GPS for immunotherapies

byDana-Farber Cancer InstituteBacteria displaying hDR18 enhance anti-tumor responses of MSLN-CAR NK cells. Credit:Nature Biotechnology(2024). DOI: 10.1038/s41587-024-02418-6Immunothe
A chemistry pioneer works to improve a flawed test for a common cancer

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a
Researchers uncover how breast cancer cells become resistant to therapy

Researchers uncover how breast cancer cells become resistant to therapy

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainAbout one-fourth of recurrent estrogen receptor-positive (ER+) breast cancers lose ER expression, which renders them res

Researchers uncover how breast cancer cells become resistant to therapy

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainAbout one-fourth of recurrent estrogen receptor-positive (ER+) breast cancers lose ER expression, which renders them res
HPV vaccine eliminates advanced skin cancer in 97-year-old

HPV vaccine eliminates advanced skin cancer in 97-year-old

(HealthDay)—The 9-valent human papillomavirus (HPV) vaccine could be a therapeutic option for patients with cutaneous squamous cell carcinoma when surgical management is not an option, according to a

HPV vaccine eliminates advanced skin cancer in 97-year-old

(HealthDay)—The 9-valent human papillomavirus (HPV) vaccine could be a therapeutic option for patients with cutaneous squamous cell carcinoma when surgical management is not an option, according to a
Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle