First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainIn patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral cris

Updated on: February 01,2024

First-line ribociclib and endocrine therapy may be more effective than combined chemotherapy in aggressive breast cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainIn patients with hormone receptor-positive, HER2-negative, advanced breast cancer—including patients with visceral cris

Updated on:February 01,2024

Discovery of new mechanism explains how ovarian cancer disables immune cells

byWeill Cornell Medical CollegeThis confocal micrograph shows two proteins,TAGLN2 (green) and FABP5 (red), are found together (yellow) on the surfaces of T cells, enabling the cells to pick up l

Updated on: November 11,2024

Discovery of new mechanism explains how ovarian cancer disables immune cells

byWeill Cornell Medical CollegeThis confocal micrograph shows two proteins,TAGLN2 (green) and FABP5 (red), are found together (yellow) on the surfaces of T cells, enabling the cells to pick up l

Updated on:November 11,2024

Cancer-seeking molecular delivery system could boost immunotherapy drug, research finds

byUniversity of Rhode IslandCredit: Unsplash/CC0 Public DomainResearchers from the University of Rhode Island and Yale University have demonstrated a promising new approach to delivering immunot

Updated on: January 23,2024

Cancer-seeking molecular delivery system could boost immunotherapy drug, research finds

byUniversity of Rhode IslandCredit: Unsplash/CC0 Public DomainResearchers from the University of Rhode Island and Yale University have demonstrated a promising new approach to delivering immunot

Updated on:January 23,2024

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b

Updated on: June 22,2024

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b

Updated on:June 22,2024

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Updated on: April 07,2024

Repurposing existing FDA-approved inhibitors may provide new treatment approach for ovarian cancer

by The Wistar InstituteCredit: The Wistar InstituteWistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for t

Updated on:April 07,2024

Discovery paves way for precision medicine in future

by University of OtagoThis high-dimensional analysis reveals the T cell signature in people with bowel cancer. The new analysis groups cells together so all cells can be viewed at once. In the pa

Updated on: April 18,2024

Discovery paves way for precision medicine in future

by University of OtagoThis high-dimensional analysis reveals the T cell signature in people with bowel cancer. The new analysis groups cells together so all cells can be viewed at once. In the pa

Updated on:April 18,2024

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Updated on: March 06,2024

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Updated on:March 06,2024

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on: March 30,2024

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on:March 30,2024

Researchers are building detailed maps of colorectal cancer to better understand the dynamics of the disease

by Harvard Medical SchoolA 3D reconstruction of colorectal cancer revealed that what was once thought to be 2D mucin pools with clusters of cancer cells floating inside is actually a complex and

Updated on: February 24,2024

Researchers are building detailed maps of colorectal cancer to better understand the dynamics of the disease

by Harvard Medical SchoolA 3D reconstruction of colorectal cancer revealed that what was once thought to be 2D mucin pools with clusters of cancer cells floating inside is actually a complex and

Updated on:February 24,2024

Investigational deep learning model may help stratify risk for patients with endometrial cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainAn investigational deep learning model requiring one histopathologic slide accurately predicted the risk of distant rec

Updated on: February 03,2024

Investigational deep learning model may help stratify risk for patients with endometrial cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainAn investigational deep learning model requiring one histopathologic slide accurately predicted the risk of distant rec

Updated on:February 03,2024

'Exhausted' immune cells in healthy women could be target for breast cancer prevention

byUniversity of CambridgeImmune cell exhaustion is observed in breast tissue from carriers of BRCA1 and BRCA2 mutations long before breast cancer develops. Credit: Sara Pensa/University of Cambr

Updated on: March 30,2024

'Exhausted' immune cells in healthy women could be target for breast cancer prevention

byUniversity of CambridgeImmune cell exhaustion is observed in breast tissue from carriers of BRCA1 and BRCA2 mutations long before breast cancer develops. Credit: Sara Pensa/University of Cambr

Updated on:March 30,2024

New study estimates preventable cancer burden linked to poor diet in the US

by Tufts UniversityA new study estimates that 5.2 percent of new invasive cancer cases reported in 2015 are associated with poor diets. Credit: Nako Kobayashi/Tufts UniversityA new modeling study

Updated on: May 21,2024

New study estimates preventable cancer burden linked to poor diet in the US

by Tufts UniversityA new study estimates that 5.2 percent of new invasive cancer cases reported in 2015 are associated with poor diets. Credit: Nako Kobayashi/Tufts UniversityA new modeling study

Updated on:May 21,2024