Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on: April 22,2024

Diverse immune cell profiles and roles found in breast cancer resistance to immunotherapy

by Baylor College of MedicineDr. Xiang 'Shawn' Zhang, the corresponding author of this work. Credit: Baylor College of MedicineIn recent years it has been increasingly appreciated that im

Updated on:April 22,2024

Drug makes tumors more susceptible to chemo

by Massachusetts Institute of TechnologyStructure of the complex containing Rev1 and JH-RE-06. The two copies of the Rev1 protein are shown in dark and light blue, while the small molecule JH-RE-

Updated on: May 25,2024

Drug makes tumors more susceptible to chemo

by Massachusetts Institute of TechnologyStructure of the complex containing Rev1 and JH-RE-06. The two copies of the Rev1 protein are shown in dark and light blue, while the small molecule JH-RE-

Updated on:May 25,2024

Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by The Spanish National Cancer Research CentreClinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm.AClinical trial treatment and s

Updated on: February 18,2024

Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer

by The Spanish National Cancer Research CentreClinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm.AClinical trial treatment and s

Updated on:February 18,2024

Better adenoma detection using a molecular marker for fluorescent imaging

by Sarah E. Glass,Vanderbilt University(a)Representative white light and corresponding fluorescence colonoscopy images (static) of B6;129 mice bearing either colorectal adenomas or normal

Updated on: February 18,2024

Better adenoma detection using a molecular marker for fluorescent imaging

by Sarah E. Glass,Vanderbilt University(a)Representative white light and corresponding fluorescence colonoscopy images (static) of B6;129 mice bearing either colorectal adenomas or normal

Updated on:February 18,2024

Existing cancer drugs have potential to benefit thousands more patients, research shows

byInstitute of Cancer ResearchSF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response. Credit:Nature Genetics(2023). DOI: 1

Updated on: January 16,2024

Existing cancer drugs have potential to benefit thousands more patients, research shows

byInstitute of Cancer ResearchSF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response. Credit:Nature Genetics(2023). DOI: 1

Updated on:January 16,2024

New gene implicated in cancer, cellular stress response

by Olivia Dimmer,Northwestern UniversityTissue-restricted expression of mammalian HAPSTR2. a Transcript abundance of HAPSTR1 and HAPSTR2 in the indicated human tissues; GTEx RNA-seq data. TPM, t

Updated on: February 18,2024

New gene implicated in cancer, cellular stress response

by Olivia Dimmer,Northwestern UniversityTissue-restricted expression of mammalian HAPSTR2. a Transcript abundance of HAPSTR1 and HAPSTR2 in the indicated human tissues; GTEx RNA-seq data. TPM, t

Updated on:February 18,2024

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on: April 01,2024

T-cell interactions vary between tumor microenvironments

by Melissa Rohman,Northwestern UniversityShown is a p-STAT3- non-reactive astrocyte (white arrow) in close proximity to a CD3+p-STAT3- T cell (blue arrow) and a CD163+p-STAT3- macrophage (red ar

Updated on:April 01,2024

Ryan Reynolds has urged 45-year-olds to screen for bowel cancer. But the case for screening in your 40s isn't clear cut

by Katy Bell and Paul Glasziou,The ConversationCredit: AI-generated imageLast week, actors Ryan Reynolds and Rob McElhenney released avideo of themselves getting colonoscopiesto enco

Updated on: January 03,2024

Ryan Reynolds has urged 45-year-olds to screen for bowel cancer. But the case for screening in your 40s isn't clear cut

by Katy Bell and Paul Glasziou,The ConversationCredit: AI-generated imageLast week, actors Ryan Reynolds and Rob McElhenney released avideo of themselves getting colonoscopiesto enco

Updated on:January 03,2024

Tumor mutations may predict response to immunotherapy

by Johns Hopkins University School of MedicineMismatch repair deficiency refers to a characteristic of some cancer cells that create a large number of mutations, or changes, in certain genes when

Updated on: April 07,2024

Tumor mutations may predict response to immunotherapy

by Johns Hopkins University School of MedicineMismatch repair deficiency refers to a characteristic of some cancer cells that create a large number of mutations, or changes, in certain genes when

Updated on:April 07,2024

Study: Cannabis use disorder increasing among veterans with psychiatric disorders

by American Psychiatric AssociationCredit: Pixabay/CC0 Public DomainResearch publishedinThe American Journal of Psychiatryfinds that during a period of increasing cannabis use i

Updated on: July 02,2024

Study: Cannabis use disorder increasing among veterans with psychiatric disorders

by American Psychiatric AssociationCredit: Pixabay/CC0 Public DomainResearch publishedinThe American Journal of Psychiatryfinds that during a period of increasing cannabis use i

Updated on:July 02,2024

Novel PET radiotracer reduces number of false-positive cancer findings after COVID-19 vaccination

by Society of Nuclear Medicine and Molecular ImagingNovel 68Ga-FAPI PET/CT offers oncologic staging without COVID-19 vaccine-related pitfalls. Credit: Tristan T. Demmert et al., Department of Nuclear

Updated on: January 15,2024

Novel PET radiotracer reduces number of false-positive cancer findings after COVID-19 vaccination

by Society of Nuclear Medicine and Molecular ImagingNovel 68Ga-FAPI PET/CT offers oncologic staging without COVID-19 vaccine-related pitfalls. Credit: Tristan T. Demmert et al., Department of Nuclear

Updated on:January 15,2024

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on: May 23,2024

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on:May 23,2024