Rethinking how cancer cells evade targeted therapy

byUniversity of California, San FranciscoA single-cell RNA atlas of human glioblastoma through recurrence.a, An overview of genomics studies on paired longitudinal GBM specimens.b, A

Updated on: January 22,2024

Rethinking how cancer cells evade targeted therapy

byUniversity of California, San FranciscoA single-cell RNA atlas of human glioblastoma through recurrence.a, An overview of genomics studies on paired longitudinal GBM specimens.b, A

Updated on:January 22,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on: April 01,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on:April 01,2024

Study reveals pathways for aggressive prostate cancer subtype

by Vanderbilt University Medical CenterScRNAseq of ICC/IDC-enriched and benign-enriched prostate. a Schematic of scRNAseq protocol of ICC/IDC-enriched and benign-enriched prostate. b Representati

Updated on: February 23,2024

Study reveals pathways for aggressive prostate cancer subtype

by Vanderbilt University Medical CenterScRNAseq of ICC/IDC-enriched and benign-enriched prostate. a Schematic of scRNAseq protocol of ICC/IDC-enriched and benign-enriched prostate. b Representati

Updated on:February 23,2024

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi

Updated on: April 14,2024

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi

Updated on:April 14,2024

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Updated on: May 13,2024

Pancreatic cancer discovery reveals how the aggressive cancer fuels its growth

by University of VirginiaThe new discovery represents the fulfillment of years of work for David F. Kashatus, Ph.D., who first proposed the research project while interviewing at UVA in 2012. Cre

Updated on:May 13,2024

Use of MMR deficiency testing in younger CRC patients is low

(HealthDay)—Fewer than half of younger adults with colorectal cancer (CRC) undergo mismatch repair (MMR) deficiency of DNA testing, according to a study published online Nov. 9 inJAMA Oncology.T

Updated on: April 22,2024

Use of MMR deficiency testing in younger CRC patients is low

(HealthDay)—Fewer than half of younger adults with colorectal cancer (CRC) undergo mismatch repair (MMR) deficiency of DNA testing, according to a study published online Nov. 9 inJAMA Oncology.T

Updated on:April 22,2024

Previous cancer treatment not tied to higher stillbirth rate

Cancer diagnosis and treatment for adolescent girls and young adult women does not appear to increase the risk of a stillbirth with a later pregnancy, according to a study published Aug. 27 in the&nbs

Updated on: February 01,2024

Previous cancer treatment not tied to higher stillbirth rate

Cancer diagnosis and treatment for adolescent girls and young adult women does not appear to increase the risk of a stillbirth with a later pregnancy, according to a study published Aug. 27 in the&nbs

Updated on:February 01,2024

Drug hobbles deadly liver cancer by stifling protein production

by University of California, San FranciscoCredit: CC0 Public DomainIn laboratory experiments, UC San Francisco researchers successfully beat back the growth of aggressive liver cancers using a su

Updated on: May 25,2024

Drug hobbles deadly liver cancer by stifling protein production

by University of California, San FranciscoCredit: CC0 Public DomainIn laboratory experiments, UC San Francisco researchers successfully beat back the growth of aggressive liver cancers using a su

Updated on:May 25,2024

Investigating the role of fatty acids in cancer cell survival

by Melissa Rohman,Northwestern UniversityIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous ep

Updated on: February 18,2024

Investigating the role of fatty acids in cancer cell survival

by Melissa Rohman,Northwestern UniversityIntermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous ep

Updated on:February 18,2024

Breast cancer patients with higher BMI more likely to experience heart damage during chemotherapy, study finds

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainBreast cancer survival rates have improved considerably in the last few decades in Colombia, but factors that increase the likel

Updated on: January 23,2024

Breast cancer patients with higher BMI more likely to experience heart damage during chemotherapy, study finds

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainBreast cancer survival rates have improved considerably in the last few decades in Colombia, but factors that increase the likel

Updated on:January 23,2024

Exercise can reduce severity of breast cancer treatment side effects

by Edith Cowan UniversityCredit: Pixabay/CC0 Public DomainBreast cancer is the most common form of the disease among women; in Australia, one in eight women will be diagnosed with breast cancer b

Updated on: February 03,2024

Exercise can reduce severity of breast cancer treatment side effects

by Edith Cowan UniversityCredit: Pixabay/CC0 Public DomainBreast cancer is the most common form of the disease among women; in Australia, one in eight women will be diagnosed with breast cancer b

Updated on:February 03,2024

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on: May 21,2024

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on:May 21,2024