An unexpected T cell exhaustion factor driving cancer immunotherapy resistance

by The University of Hong KongGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111647A research team from the LKS Faculty of Medicine, the University of Hong

Updated on: January 30,2024

An unexpected T cell exhaustion factor driving cancer immunotherapy resistance

by The University of Hong KongGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111647A research team from the LKS Faculty of Medicine, the University of Hong

Updated on:January 30,2024

Researchers complete largest genomic analysis of Merkel cell carcinoma patients

by H. Lee Moffitt Cancer Center & Research InstituteCredit: CC0 Public DomainMerkel cell carcinoma (MCC) is a rare, aggressive skin tumor that is diagnosed in approximately 2,000 people each

Updated on: June 04,2024

Researchers complete largest genomic analysis of Merkel cell carcinoma patients

by H. Lee Moffitt Cancer Center & Research InstituteCredit: CC0 Public DomainMerkel cell carcinoma (MCC) is a rare, aggressive skin tumor that is diagnosed in approximately 2,000 people each

Updated on:June 04,2024

Fixed-duration ibrutinib plus venetoclax may benefit patients with high-risk chronic lymphocytic leukemia

by American Association for Cancer ResearchCredit: CC0 Public DomainFirst-line ibrutinib (Imbruvica) plus venetoclax (Venclexta) led to high response and survival rates in patients with chronic l

Updated on: January 30,2024

Fixed-duration ibrutinib plus venetoclax may benefit patients with high-risk chronic lymphocytic leukemia

by American Association for Cancer ResearchCredit: CC0 Public DomainFirst-line ibrutinib (Imbruvica) plus venetoclax (Venclexta) led to high response and survival rates in patients with chronic l

Updated on:January 30,2024

New heated drug baths provide hope for patients with stomach cancer

by Megan Lakatos,Mayo ClinicCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have used a new approach to chemotherapy to more than double the typical survival rate for patients with stom

Updated on: April 28,2024

New heated drug baths provide hope for patients with stomach cancer

by Megan Lakatos,Mayo ClinicCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have used a new approach to chemotherapy to more than double the typical survival rate for patients with stom

Updated on:April 28,2024

Researchers develop tool that reduces errors in stem cell transplant reporting

by Children's Hospital of PhiladelphiaCredit: CC0 Public DomainResearchers at Children's Hospital of Philadelphia (CHOP) have developed a custom-built application to automate determinatio

Updated on: February 20,2024

Researchers develop tool that reduces errors in stem cell transplant reporting

by Children's Hospital of PhiladelphiaCredit: CC0 Public DomainResearchers at Children's Hospital of Philadelphia (CHOP) have developed a custom-built application to automate determinatio

Updated on:February 20,2024

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on: June 08,2024

Researchers characterize mechanism of action of CAR T cells

by H. Lee Moffitt Cancer Center & Research InstituteScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDThe sci

Updated on:June 08,2024

Ryan Reynolds has urged 45-year-olds to screen for bowel cancer. But the case for screening in your 40s isn't clear cut

by Katy Bell and Paul Glasziou,The ConversationCredit: AI-generated imageLast week, actors Ryan Reynolds and Rob McElhenney released avideo of themselves getting colonoscopiesto enco

Updated on: January 03,2024

Ryan Reynolds has urged 45-year-olds to screen for bowel cancer. But the case for screening in your 40s isn't clear cut

by Katy Bell and Paul Glasziou,The ConversationCredit: AI-generated imageLast week, actors Ryan Reynolds and Rob McElhenney released avideo of themselves getting colonoscopiesto enco

Updated on:January 03,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on: January 02,2024

Reprogramming of immune cells shown to fight off melanoma

byUniversity of BristolmiR223 inhibition reduces cancer progression in zebrafish. A) Pigmentation of the tailfin quantified by threshold analysis of tail region (red dotted outline) in 1-month-o

Updated on:January 02,2024

New molecule reduces the aggressiveness of pediatric cancer

by André Julião,FAPESPA microRNA inhibitor identified by researchers at the FAPESP-supported Human Genome and Stem Cell Research Center reduced the sizes of aggressive tumors and improved

Updated on: March 06,2024

New molecule reduces the aggressiveness of pediatric cancer

by André Julião,FAPESPA microRNA inhibitor identified by researchers at the FAPESP-supported Human Genome and Stem Cell Research Center reduced the sizes of aggressive tumors and improved

Updated on:March 06,2024

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Updated on: February 24,2024

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Updated on:February 24,2024

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on: March 30,2024

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on:March 30,2024

Salmonella research unlocks the potential of bacteria to treat bowel cancer

byUniversity of GlasgowTILs from mice treated with Salmonella are functionally defective. Credit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-024-00159-2Fighting bowel cancer w

Updated on: December 01,2024

Salmonella research unlocks the potential of bacteria to treat bowel cancer

byUniversity of GlasgowTILs from mice treated with Salmonella are functionally defective. Credit:EMBO Molecular Medicine(2024). DOI: 10.1038/s44321-024-00159-2Fighting bowel cancer w

Updated on:December 01,2024