Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on: April 01,2024

Synthetic molecule proves able to mitigate heart failure in translational study

by Maria Fernanda Ziegler,FAPESPThe vicious cycle of heart failure (HF). (i) Impaired aldehyde metabolism by aldehyde dehydrogenase 2 (ALDH2); (ii) accumulation of 4-hydroxynonenal (4-HNE), a re

Updated on:April 01,2024

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on: March 30,2024

Subtyping of breast cancer cell lines reveals insights into cancer-relevant genes

by Manuela Schüngel, Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbHWaterfall plot depicting recurrent non-synonymous mutations in BC cell lines. Mutations were calle

Updated on:March 30,2024

Deep learning algorithm may streamline lung cancer radiotherapy treatment

byBrigham and Women's HospitalCredit: Unsplash/CC0 Public DomainLung cancer, the most common cancer worldwide, is targeted with radiation therapy (RT) in nearly one-half of cases. RT plannin

Updated on: January 04,2024

Deep learning algorithm may streamline lung cancer radiotherapy treatment

byBrigham and Women's HospitalCredit: Unsplash/CC0 Public DomainLung cancer, the most common cancer worldwide, is targeted with radiation therapy (RT) in nearly one-half of cases. RT plannin

Updated on:January 04,2024

Leukemia, lymphoma squarely in sights of new class of drugs

by Will Sansom,University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainUT Health San Antonio researchers, working with collaborators at the University of Florida, have d

Updated on: March 08,2024

Leukemia, lymphoma squarely in sights of new class of drugs

by Will Sansom,University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainUT Health San Antonio researchers, working with collaborators at the University of Florida, have d

Updated on:March 08,2024

Researchers uncovers promising cancer target for liposarcoma

by National University of SingaporeCredit: CC0 Public DomainA study conducted by a team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of

Updated on: June 19,2024

Researchers uncovers promising cancer target for liposarcoma

by National University of SingaporeCredit: CC0 Public DomainA study conducted by a team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of

Updated on:June 19,2024

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on: May 21,2024

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on:May 21,2024

Research highlights industry and regulatory perspectives on improving diversity in clinical trials

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainClinical Cancer Researchpublished an article today outlining steps clinical trial sponsors can take to improve di

Updated on: February 18,2024

Research highlights industry and regulatory perspectives on improving diversity in clinical trials

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainClinical Cancer Researchpublished an article today outlining steps clinical trial sponsors can take to improve di

Updated on:February 18,2024

Study: Access to cannabis for cancer patients is not equitable

by Bert Gambini,University at BuffaloCredit: Pixabay/CC0 Public DomainThe same factors driving many health care disparities in the U.S. are also affecting who has access to cannabis for managing

Updated on: January 16,2024

Study: Access to cannabis for cancer patients is not equitable

by Bert Gambini,University at BuffaloCredit: Pixabay/CC0 Public DomainThe same factors driving many health care disparities in the U.S. are also affecting who has access to cannabis for managing

Updated on:January 16,2024

Researchers map intricacies of lung cancer in one of their own

by Krista Conger,Stanford University Medical CenterJames Spudich (left) made an unusual offer last fall to colleague Mark Krasnow: a sample of a lung tumor that was to be removed from Spudich th

Updated on: June 04,2024

Researchers map intricacies of lung cancer in one of their own

by Krista Conger,Stanford University Medical CenterJames Spudich (left) made an unusual offer last fall to colleague Mark Krasnow: a sample of a lung tumor that was to be removed from Spudich th

Updated on:June 04,2024

Software program that looks for the most effective drugs helps to personalize cancer treatments

byThe Spanish National Cancer Research CentreGraphical Abstract. Credit:Nucleic Acids Research(2023). DOI: 10.1093/nar/gkad412Precision medicine seeks to adapt treatments to the char

Updated on: January 16,2024

Software program that looks for the most effective drugs helps to personalize cancer treatments

byThe Spanish National Cancer Research CentreGraphical Abstract. Credit:Nucleic Acids Research(2023). DOI: 10.1093/nar/gkad412Precision medicine seeks to adapt treatments to the char

Updated on:January 16,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on: June 22,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on:June 22,2024

Breast cancer test could guide treatment for more aggressive subtype

byInstitute of Cancer ResearchKi67 changes from baseline to surgery stratified by intrinsic subtype at baseline within a. Treated and b. Controls. Abbreviations: HER2-E, HER2-Enriched Subtype; L

Updated on: January 02,2024

Breast cancer test could guide treatment for more aggressive subtype

byInstitute of Cancer ResearchKi67 changes from baseline to surgery stratified by intrinsic subtype at baseline within a. Treated and b. Controls. Abbreviations: HER2-E, HER2-Enriched Subtype; L

Updated on:January 02,2024