An unexpected T cell exhaustion factor driving cancer immunotherapy resistance

by The University of Hong KongGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111647A research team from the LKS Faculty of Medicine, the University of Hong

Updated on: January 30,2024

An unexpected T cell exhaustion factor driving cancer immunotherapy resistance

by The University of Hong KongGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111647A research team from the LKS Faculty of Medicine, the University of Hong

Updated on:January 30,2024

Tumors form temporary structures to avoid immunotherapy treatments

byeLifeTumor-reactive T cells induce transient cell-in-cell structure. (A) Mean percentage of cell-in-cell tumor formations following incubation of B16F10 cells with immune cells (n=4). (B) Repr

Updated on: January 22,2024

Tumors form temporary structures to avoid immunotherapy treatments

byeLifeTumor-reactive T cells induce transient cell-in-cell structure. (A) Mean percentage of cell-in-cell tumor formations following incubation of B16F10 cells with immune cells (n=4). (B) Repr

Updated on:January 22,2024

Oncology researchers raise ethics concerns posed by patient-facing artificial intelligence

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainReady or not, patients with cancer are increasingly likely to find themselves interacting with artificial intelligence technologies

Updated on: April 07,2024

Oncology researchers raise ethics concerns posed by patient-facing artificial intelligence

by Dana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainReady or not, patients with cancer are increasingly likely to find themselves interacting with artificial intelligence technologies

Updated on:April 07,2024

Tumor mutations may predict response to immunotherapy

by Johns Hopkins University School of MedicineMismatch repair deficiency refers to a characteristic of some cancer cells that create a large number of mutations, or changes, in certain genes when

Updated on: April 07,2024

Tumor mutations may predict response to immunotherapy

by Johns Hopkins University School of MedicineMismatch repair deficiency refers to a characteristic of some cancer cells that create a large number of mutations, or changes, in certain genes when

Updated on:April 07,2024

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on: May 23,2024

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on:May 23,2024

Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

by Worldwide Cancer ResearchFlow chart with the design of a clinical trial with azeliragon in combination with radiotherapy in patients with brain metastases from non-small-cell lung cancer, breast ca

Updated on: January 02,2024

Brain tumor clinical trial: Failed Alzheimer's drug that boosts effect of radiotherapy to be tested in humans this year

by Worldwide Cancer ResearchFlow chart with the design of a clinical trial with azeliragon in combination with radiotherapy in patients with brain metastases from non-small-cell lung cancer, breast ca

Updated on:January 02,2024

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Updated on: February 24,2024

Drug turns cancer gene into 'eat me' flag for immune system

by Robin Marks,University of California, San FranciscoMicroscopy of a lung tumor biopsy. Credit: Lin MaTumor cells are notoriously good at evading the human immune system; they put up physical w

Updated on:February 24,2024

Researchers identify potential target in myeloid malignancies

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI165510Researchers at Children's Hospital of Philadelp

Updated on: February 18,2024

Researchers identify potential target in myeloid malignancies

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI165510Researchers at Children's Hospital of Philadelp

Updated on:February 18,2024

Taming overactive molecular signaling in renal cell cancer

by Johns Hopkins University School of MedicineMurine renal tumors with Tsc2 loss have increased TFEB/TFE3 nuclear localization. Credit: Clarence Rachel Villanueva and Adrianna A. Mendes,Nat

Updated on: February 01,2024

Taming overactive molecular signaling in renal cell cancer

by Johns Hopkins University School of MedicineMurine renal tumors with Tsc2 loss have increased TFEB/TFE3 nuclear localization. Credit: Clarence Rachel Villanueva and Adrianna A. Mendes,Nat

Updated on:February 01,2024

Increasing level of alcohol intake may raise risk for cancer

Adults who increase their alcohol consumption may have a higher risk for alcohol-related cancers and all cancers versus adults who had sustained quitting or reduced levels of drinking, according to a

Updated on: February 18,2024

Increasing level of alcohol intake may raise risk for cancer

Adults who increase their alcohol consumption may have a higher risk for alcohol-related cancers and all cancers versus adults who had sustained quitting or reduced levels of drinking, according to a

Updated on:February 18,2024

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on: January 12,2024

New research casts doubt on role of fungus in driving pancreatic cancer

byDuke University Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainFour years ago, a report that a common species of fungu

Updated on:January 12,2024

Algorithm helps doctors identify more aggressive types of basal cell carcinoma

by Elin Lindström,University of GothenburgCredit: Paul Björkman (Sahlgrenska Universitetssjukhuset)An algorithm can help health care professionals recognize which patients have a highly aggressi

Updated on: July 05,2024

Algorithm helps doctors identify more aggressive types of basal cell carcinoma

by Elin Lindström,University of GothenburgCredit: Paul Björkman (Sahlgrenska Universitetssjukhuset)An algorithm can help health care professionals recognize which patients have a highly aggressi

Updated on:July 05,2024