The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on: January 02,2024

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on:January 02,2024

New biomarker strategy devised to screen for, diagnose deadly heart complication from cancer treatment

byUniversity of MichiganCredit: Unsplash/CC0 Public DomainResearchers at Michigan Medicine have devised a new biomarker-based strategy to screen for a rare and deadly complication caused by mono

Updated on: January 12,2024

New biomarker strategy devised to screen for, diagnose deadly heart complication from cancer treatment

byUniversity of MichiganCredit: Unsplash/CC0 Public DomainResearchers at Michigan Medicine have devised a new biomarker-based strategy to screen for a rare and deadly complication caused by mono

Updated on:January 12,2024

Healthy gut bacteria can help fight cancer in other parts of the body, researchers find

by UT Southwestern Medical CenterImmune checkpoint therapy (ICT) helps gut microbiota travel from the gut to the lymph nodes where they activate immune cells (dendritic cells and T cells). Ultima

Updated on: February 01,2024

Healthy gut bacteria can help fight cancer in other parts of the body, researchers find

by UT Southwestern Medical CenterImmune checkpoint therapy (ICT) helps gut microbiota travel from the gut to the lymph nodes where they activate immune cells (dendritic cells and T cells). Ultima

Updated on:February 01,2024

Taming overactive molecular signaling in renal cell cancer

by Johns Hopkins University School of MedicineMurine renal tumors with Tsc2 loss have increased TFEB/TFE3 nuclear localization. Credit: Clarence Rachel Villanueva and Adrianna A. Mendes,Nat

Updated on: February 01,2024

Taming overactive molecular signaling in renal cell cancer

by Johns Hopkins University School of MedicineMurine renal tumors with Tsc2 loss have increased TFEB/TFE3 nuclear localization. Credit: Clarence Rachel Villanueva and Adrianna A. Mendes,Nat

Updated on:February 01,2024

Study shows multiple beams, intervals in delivery decrease the skin-saving benefits of FLASH radiotherapy for cancer

by Katie Pence,University of CincinnatiCredit: CC0 Public DomainA published study by researchers at the University of Cincinnati Cancer Center and Cincinnati Children's Hospital Medical Cent

Updated on: January 16,2024

Study shows multiple beams, intervals in delivery decrease the skin-saving benefits of FLASH radiotherapy for cancer

by Katie Pence,University of CincinnatiCredit: CC0 Public DomainA published study by researchers at the University of Cincinnati Cancer Center and Cincinnati Children's Hospital Medical Cent

Updated on:January 16,2024

Researchers discover how malignant melanoma eludes immune cells

by Alan Dove,Columbia University Irving Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.05.014Malignant melanoma, a dangerous type of skin cancer, deploys an elegan

Updated on: February 03,2024

Researchers discover how malignant melanoma eludes immune cells

by Alan Dove,Columbia University Irving Medical CenterCredit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.05.014Malignant melanoma, a dangerous type of skin cancer, deploys an elegan

Updated on:February 03,2024

A new blood test could detect early stage melanoma in more than 80% of patients

by Mel Ziman,The ConversationCredit: AI-generated imageMelanoma killsmore than 1,700 Australians every year, which is more than thenational road toll. But the good news is it's t

Updated on: May 21,2024

A new blood test could detect early stage melanoma in more than 80% of patients

by Mel Ziman,The ConversationCredit: AI-generated imageMelanoma killsmore than 1,700 Australians every year, which is more than thenational road toll. But the good news is it's t

Updated on:May 21,2024

Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on: January 23,2024

Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on:January 23,2024

A novel strategy to suppress triple negative breast cancer growth

by Homa Shalchi,Baylor College of MedicineCredit:PLOS Biology(2023). DOI: 10.1371/journal.pbio.3002227In 2022, a team of researchers at Baylor College of Medicinediscovered&nbs

Updated on: February 01,2024

A novel strategy to suppress triple negative breast cancer growth

by Homa Shalchi,Baylor College of MedicineCredit:PLOS Biology(2023). DOI: 10.1371/journal.pbio.3002227In 2022, a team of researchers at Baylor College of Medicinediscovered&nbs

Updated on:February 01,2024

In situ, invasive melanoma diagnoses decreased in 2020

by Elana GotkineDuring 2020, there were decreases seen for in situ and invasive melanoma diagnoses, according to a research letter published online Sept. 6 inJAMA Dermatology.Daniel Y. Kim, from

Updated on: January 29,2024

In situ, invasive melanoma diagnoses decreased in 2020

by Elana GotkineDuring 2020, there were decreases seen for in situ and invasive melanoma diagnoses, according to a research letter published online Sept. 6 inJAMA Dermatology.Daniel Y. Kim, from

Updated on:January 29,2024

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on: April 28,2024

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on:April 28,2024

Experts call for a targeted approach to cancer prevention

by University of StirlingCredit: CC0 Public DomainPolicymakers around the world should consider introducing more targeted early interventions in a bid to tackle cancer, according to experts at th

Updated on: April 07,2024

Experts call for a targeted approach to cancer prevention

by University of StirlingCredit: CC0 Public DomainPolicymakers around the world should consider introducing more targeted early interventions in a bid to tackle cancer, according to experts at th

Updated on:April 07,2024