Probing RNA epigenetics and chromatin structures to predict drug resistance in leukemia

by University of Chicago Medical Center5-AZA-sensitive and 5-AZA-resistant leukemia cells have distinctly different chromatin structures. Credit: Jason ChengDrug resistance is a major obstacle to

Updated on: March 09,2024 17

Probing RNA epigenetics and chromatin structures to predict drug resistance in leukemia

by University of Chicago Medical Center5-AZA-sensitive and 5-AZA-resistant leukemia cells have distinctly different chromatin structures. Credit: Jason ChengDrug resistance is a major obstacle to

Updated on:March 09,2024 17

New model shows potential for human papillomavirus vaccination switch to 1-dose gender-neutral approach

byCanadian Medical Association JournalCredit: Unsplash/CC0 Public DomainCanadian vaccination programs could switch to a 1-dose gender-neutral human papillomavirus (HPV) vaccination approach and

Updated on: November 11,2024 0

New model shows potential for human papillomavirus vaccination switch to 1-dose gender-neutral approach

byCanadian Medical Association JournalCredit: Unsplash/CC0 Public DomainCanadian vaccination programs could switch to a 1-dose gender-neutral human papillomavirus (HPV) vaccination approach and

Updated on:November 11,2024 0

Research reveals previously unknown qualities of a gene vital to a cell's mitochondrial structure and function

by Rachel Sauer,University of Colorado at BoulderModel of the human S-OPA1 bound to membranes. Credit:Nature(2023). DOI: 10.1038/s41586-023-06441-6A key takeaway from first-year biol

Updated on: July 02,2024 6

Research reveals previously unknown qualities of a gene vital to a cell's mitochondrial structure and function

by Rachel Sauer,University of Colorado at BoulderModel of the human S-OPA1 bound to membranes. Credit:Nature(2023). DOI: 10.1038/s41586-023-06441-6A key takeaway from first-year biol

Updated on:July 02,2024 6

Findings reveal unexpected role of protein OTX2 that drives aggressive medulloblastoma

byBaylor College of MedicineCredit: Unsplash/CC0 Public DomainIn a reportpublishedinNature Cell Biology, researchers at Baylor College of Medicine, Texas Children's Hospita

Updated on: August 03,2024 0

Findings reveal unexpected role of protein OTX2 that drives aggressive medulloblastoma

byBaylor College of MedicineCredit: Unsplash/CC0 Public DomainIn a reportpublishedinNature Cell Biology, researchers at Baylor College of Medicine, Texas Children's Hospita

Updated on:August 03,2024 0

Atezolizumab + bevacizumab shows benefit in met renal CA

(HealthDay)—For patients with metastatic renal cell carcinoma (mRCC), atezolizumab plus bevacizumab is associated with a progression-free survival benefit versus sunitinib, according to a study presen

Updated on: March 30,2024 13

Atezolizumab + bevacizumab shows benefit in met renal CA

(HealthDay)—For patients with metastatic renal cell carcinoma (mRCC), atezolizumab plus bevacizumab is associated with a progression-free survival benefit versus sunitinib, according to a study presen

Updated on:March 30,2024 13

Fecal microbe transplants help cancer patients respond to immunotherapy and shrink tumors

by Diwakar Davar,The ConversationCancer patients who responded well to immunotherapy donated stool samples. Their stool was processed to yield material for a fecal microbe transplant. Credit: Di

Updated on: June 22,2024 7

Fecal microbe transplants help cancer patients respond to immunotherapy and shrink tumors

by Diwakar Davar,The ConversationCancer patients who responded well to immunotherapy donated stool samples. Their stool was processed to yield material for a fecal microbe transplant. Credit: Di

Updated on:June 22,2024 7

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Updated on: March 06,2024 16

Advanced ovarian cancer drug gets initial 'no' for NHS in England

by Cancer Research UKCC0 Public domainA targeted drug with potential to slow the progress of ovarian cancer has been rejected for use on the NHS in England.In making its provisional decision on r

Updated on:March 06,2024 16

Thalidomide reveals path for targeting undruggable transcription factors for cancer treatment

by Tom Ulrich,Broad Institute of MIT and HarvardCredit: Susanna M. Hamilton, Broad CommunicationsThalidomide, a morning-sickness drug recalled in the 1960s because it caused devastating birth de

Updated on: March 06,2024 19

Thalidomide reveals path for targeting undruggable transcription factors for cancer treatment

by Tom Ulrich,Broad Institute of MIT and HarvardCredit: Susanna M. Hamilton, Broad CommunicationsThalidomide, a morning-sickness drug recalled in the 1960s because it caused devastating birth de

Updated on:March 06,2024 19

Researchers identify possible approach to prevent cancer from evolving to resist treatment

by University of California, Los AngelesSingle-agent inhibitory potencies in human melanoma, PDAC, and NSCLC clonogenic growth assays. A to G, Long-term clonogenic growth of indicated BRAFV600MUT

Updated on: February 18,2024 16

Researchers identify possible approach to prevent cancer from evolving to resist treatment

by University of California, Los AngelesSingle-agent inhibitory potencies in human melanoma, PDAC, and NSCLC clonogenic growth assays. A to G, Long-term clonogenic growth of indicated BRAFV600MUT

Updated on:February 18,2024 16

Thermo-chemotherapy combo eradicates primary and metastatic tumors in mice

by National Institutes of HealthThe theranostic particle is injected into the tail vein. When it reaches the breast tumor, near infrared (NIR) laser light is applied to release the chemotherapy.

Updated on: March 01,2024 19

Thermo-chemotherapy combo eradicates primary and metastatic tumors in mice

by National Institutes of HealthThe theranostic particle is injected into the tail vein. When it reaches the breast tumor, near infrared (NIR) laser light is applied to release the chemotherapy.

Updated on:March 01,2024 19

Study: ChemoID platform-predicted treatments lead to longer survival for glioblastoma patients

by Tim Tedeschi,University of CincinnatiGraphical Abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101025New multi-institutional phase 3 clinical trial data pub

Updated on: February 01,2024 20

Study: ChemoID platform-predicted treatments lead to longer survival for glioblastoma patients

by Tim Tedeschi,University of CincinnatiGraphical Abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101025New multi-institutional phase 3 clinical trial data pub

Updated on:February 01,2024 20

Increasing level of alcohol intake may raise risk for cancer

Adults who increase their alcohol consumption may have a higher risk for alcohol-related cancers and all cancers versus adults who had sustained quitting or reduced levels of drinking, according to a

Updated on: February 18,2024 17

Increasing level of alcohol intake may raise risk for cancer

Adults who increase their alcohol consumption may have a higher risk for alcohol-related cancers and all cancers versus adults who had sustained quitting or reduced levels of drinking, according to a

Updated on:February 18,2024 17