Gut bacteria engineered to act as tumor GPS for immunotherapies

byDana-Farber Cancer InstituteBacteria displaying hDR18 enhance anti-tumor responses of MSLN-CAR NK cells. Credit:Nature Biotechnology(2024). DOI: 10.1038/s41587-024-02418-6Immunothe

Updated on: October 10,2024

Gut bacteria engineered to act as tumor GPS for immunotherapies

byDana-Farber Cancer InstituteBacteria displaying hDR18 enhance anti-tumor responses of MSLN-CAR NK cells. Credit:Nature Biotechnology(2024). DOI: 10.1038/s41587-024-02418-6Immunothe

Updated on:October 10,2024

Study shows immunotherapy may benefit a subset of patients with penile cancer

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainPenile cancer is a rare disease with approximately 2,070 new cases each year in the U.S. Treatment options are limited and typical

Updated on: January 22,2024

Study shows immunotherapy may benefit a subset of patients with penile cancer

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainPenile cancer is a rare disease with approximately 2,070 new cases each year in the U.S. Treatment options are limited and typical

Updated on:January 22,2024

New test predicts chance of living more than a year on targeted breast cancer treatment

by Institute of Cancer ResearchBreast cancer cells stained for DNA (red), NFkB (green), and a reactive oxygen species probe (blue). Credit: Julia Sero / the ICR, 2011A new test could pick out wom

Updated on: May 23,2024

New test predicts chance of living more than a year on targeted breast cancer treatment

by Institute of Cancer ResearchBreast cancer cells stained for DNA (red), NFkB (green), and a reactive oxygen species probe (blue). Credit: Julia Sero / the ICR, 2011A new test could pick out wom

Updated on:May 23,2024

Scientists discover sweet spot of activity in immune system key to fighting cancer

by University of SouthamptonConcentrated CD40 receptions (grey wavy lines) on the immune cell surface. Credit: University of SouthamptonScientists at the University of Southampton have shown how

Updated on: March 12,2024

Scientists discover sweet spot of activity in immune system key to fighting cancer

by University of SouthamptonConcentrated CD40 receptions (grey wavy lines) on the immune cell surface. Credit: University of SouthamptonScientists at the University of Southampton have shown how

Updated on:March 12,2024

Inherited mutations may play a role in pancreatic cancer development

by Johns Hopkins University School of MedicineAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA small, retrospective study has found tha

Updated on: May 13,2024

Inherited mutations may play a role in pancreatic cancer development

by Johns Hopkins University School of MedicineAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainA small, retrospective study has found tha

Updated on:May 13,2024

New study shows association of historical housing discrimination and shortfalls in colon cancer treatment

by Jeff Hansen,University of Alabama at BirminghamMap of redlining in Birmingham, 1933. Credit: Public domain, Wikimedia CommonsA nationwide study of 196 cities shows that housing discrimination

Updated on: March 30,2024

New study shows association of historical housing discrimination and shortfalls in colon cancer treatment

by Jeff Hansen,University of Alabama at BirminghamMap of redlining in Birmingham, 1933. Credit: Public domain, Wikimedia CommonsA nationwide study of 196 cities shows that housing discrimination

Updated on:March 30,2024

Investigational deep learning model may help stratify risk for patients with endometrial cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainAn investigational deep learning model requiring one histopathologic slide accurately predicted the risk of distant rec

Updated on: February 03,2024

Investigational deep learning model may help stratify risk for patients with endometrial cancer

by American Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainAn investigational deep learning model requiring one histopathologic slide accurately predicted the risk of distant rec

Updated on:February 03,2024

Study shows multiple beams, intervals in delivery decrease the skin-saving benefits of FLASH radiotherapy for cancer

by Katie Pence,University of CincinnatiCredit: CC0 Public DomainA published study by researchers at the University of Cincinnati Cancer Center and Cincinnati Children's Hospital Medical Cent

Updated on: January 16,2024

Study shows multiple beams, intervals in delivery decrease the skin-saving benefits of FLASH radiotherapy for cancer

by Katie Pence,University of CincinnatiCredit: CC0 Public DomainA published study by researchers at the University of Cincinnati Cancer Center and Cincinnati Children's Hospital Medical Cent

Updated on:January 16,2024

Discovery of new mechanism explains how ovarian cancer disables immune cells

byWeill Cornell Medical CollegeThis confocal micrograph shows two proteins,TAGLN2 (green) and FABP5 (red), are found together (yellow) on the surfaces of T cells, enabling the cells to pick up l

Updated on: November 11,2024

Discovery of new mechanism explains how ovarian cancer disables immune cells

byWeill Cornell Medical CollegeThis confocal micrograph shows two proteins,TAGLN2 (green) and FABP5 (red), are found together (yellow) on the surfaces of T cells, enabling the cells to pick up l

Updated on:November 11,2024

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b

Updated on: June 22,2024

Researchers uncover new targets for breast cancers resistant to standard therapies

by Leslie Cantu,Medical University of South CarolinaSOC therapy commonly induces DNA damage, BRCAness and toxic PARP1 trapping, leading to transcriptional blockage and growth inhibition in ER+ b

Updated on:June 22,2024

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on: May 23,2024

A chemistry pioneer works to improve a flawed test for a common cancer

by Clare Milliken,Northwestern UniversityKelleher says top-down proteomics provides a more comprehensiveunderstanding of human proteins than bottom-up proteomics, which is both imprecise a

Updated on:May 23,2024

Doctors try CRISPR gene editing for cancer, a 1st in the US

by Marilynn MarchioneIn this January 2019 image made from video provided by Penn Medicine, IV bags of CRISPR-edited T cells are prepared for administering to a patient at the Abramson Cancer Center in

Updated on: May 17,2024

Doctors try CRISPR gene editing for cancer, a 1st in the US

by Marilynn MarchioneIn this January 2019 image made from video provided by Penn Medicine, IV bags of CRISPR-edited T cells are prepared for administering to a patient at the Abramson Cancer Center in

Updated on:May 17,2024