Improving CAR T-cell and monoclonal antibody treatment through epitope editing

by Justin Jackson , Medical XpressCredit: CC0 Public DomainIn a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published inNature, researchers at t

Updated on: January 07,2024

Improving CAR T-cell and monoclonal antibody treatment through epitope editing

by Justin Jackson , Medical XpressCredit: CC0 Public DomainIn a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published inNature, researchers at t

Updated on:January 07,2024

1999 to 2018 saw increase in cancer survivors with functional limitation, finds research

by Elana GotkineFrom 1999 to 2018, there was a more than twofold increase in the number of cancer survivors reporting functional limitations, according to a research letter published online May 11 in&

Updated on: January 23,2024

1999 to 2018 saw increase in cancer survivors with functional limitation, finds research

by Elana GotkineFrom 1999 to 2018, there was a more than twofold increase in the number of cancer survivors reporting functional limitations, according to a research letter published online May 11 in&

Updated on:January 23,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on: February 03,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on:February 03,2024

Researchers map intricacies of lung cancer in one of their own

by Krista Conger,Stanford University Medical CenterJames Spudich (left) made an unusual offer last fall to colleague Mark Krasnow: a sample of a lung tumor that was to be removed from Spudich th

Updated on: June 04,2024

Researchers map intricacies of lung cancer in one of their own

by Krista Conger,Stanford University Medical CenterJames Spudich (left) made an unusual offer last fall to colleague Mark Krasnow: a sample of a lung tumor that was to be removed from Spudich th

Updated on:June 04,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on: June 22,2024

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on:June 22,2024

App an effective tool to record sun exposure

by Queensland University of TechnologyCredit: Queensland University of TechnologyA smartphone app is an accessible tool that reliably measures the amount of exposure to the sun's skin-damagin

Updated on: March 30,2024

App an effective tool to record sun exposure

by Queensland University of TechnologyCredit: Queensland University of TechnologyA smartphone app is an accessible tool that reliably measures the amount of exposure to the sun's skin-damagin

Updated on:March 30,2024

Country-specific norms created for cancer-related quality of life

(HealthDay)—Country-specific norms have been established for the European Organisation for Research and Treatment of Cancer (EORTC) questionnaire to measure the self-reported quality of life of cancer

Updated on: April 14,2024

Country-specific norms created for cancer-related quality of life

(HealthDay)—Country-specific norms have been established for the European Organisation for Research and Treatment of Cancer (EORTC) questionnaire to measure the self-reported quality of life of cancer

Updated on:April 14,2024

Scientists discover sweet spot of activity in immune system key to fighting cancer

by University of SouthamptonConcentrated CD40 receptions (grey wavy lines) on the immune cell surface. Credit: University of SouthamptonScientists at the University of Southampton have shown how

Updated on: March 12,2024

Scientists discover sweet spot of activity in immune system key to fighting cancer

by University of SouthamptonConcentrated CD40 receptions (grey wavy lines) on the immune cell surface. Credit: University of SouthamptonScientists at the University of Southampton have shown how

Updated on:March 12,2024

Children with resistant leukemia given CRISPR-edited T cells: Phase 1 study results reported

byUniversity College LondonAn artist’s depiction of a T cell. Credit: NIAIDResearchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (

Updated on: January 02,2024

Children with resistant leukemia given CRISPR-edited T cells: Phase 1 study results reported

byUniversity College LondonAn artist’s depiction of a T cell. Credit: NIAIDResearchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (

Updated on:January 02,2024

Metachronous pathology assessed in young-onset colorectal cancer survivors

The incidence rate of clinically significant metachronous colorectal pathology is 32 per 1,000 person-years after index young-onset colorectal cancer (YOCRC), according to a research letter published

Updated on: January 02,2024

Metachronous pathology assessed in young-onset colorectal cancer survivors

The incidence rate of clinically significant metachronous colorectal pathology is 32 per 1,000 person-years after index young-onset colorectal cancer (YOCRC), according to a research letter published

Updated on:January 02,2024

Use of MMR deficiency testing in younger CRC patients is low

(HealthDay)—Fewer than half of younger adults with colorectal cancer (CRC) undergo mismatch repair (MMR) deficiency of DNA testing, according to a study published online Nov. 9 inJAMA Oncology.T

Updated on: April 22,2024

Use of MMR deficiency testing in younger CRC patients is low

(HealthDay)—Fewer than half of younger adults with colorectal cancer (CRC) undergo mismatch repair (MMR) deficiency of DNA testing, according to a study published online Nov. 9 inJAMA Oncology.T

Updated on:April 22,2024

Taming overactive molecular signaling in renal cell cancer

by Johns Hopkins University School of MedicineMurine renal tumors with Tsc2 loss have increased TFEB/TFE3 nuclear localization. Credit: Clarence Rachel Villanueva and Adrianna A. Mendes,Nat

Updated on: February 01,2024

Taming overactive molecular signaling in renal cell cancer

by Johns Hopkins University School of MedicineMurine renal tumors with Tsc2 loss have increased TFEB/TFE3 nuclear localization. Credit: Clarence Rachel Villanueva and Adrianna A. Mendes,Nat

Updated on:February 01,2024