Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

by Caroline Wallace,Medical University of South CarolinaGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111742MUSC Hollings Cancer Center researchers have i

Updated on: January 02,2024 9

Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

by Caroline Wallace,Medical University of South CarolinaGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111742MUSC Hollings Cancer Center researchers have i

Updated on:January 02,2024 9

Drugmakers are abandoning cheap generics, and now US cancer patients can't get meds, say doctors

by Arthur AllenCredit: CC0 Public DomainOn Nov. 22, three FDA inspectors arrived at the sprawling Intas Pharmaceuticals plant south of Ahmedabad, India, and found hundreds of trash bags full of shredd

Updated on: February 03,2024 20

Drugmakers are abandoning cheap generics, and now US cancer patients can't get meds, say doctors

by Arthur AllenCredit: CC0 Public DomainOn Nov. 22, three FDA inspectors arrived at the sprawling Intas Pharmaceuticals plant south of Ahmedabad, India, and found hundreds of trash bags full of shredd

Updated on:February 03,2024 20

New class of cancer mutations discovered in so-called 'junk' DNA

byGarvan Institute of Medical ResearchVisualized DNA damage (green) in human breast cancer cells (blue). Credit: Garvan InstituteUsing artificial intelligence, Garvan Institute researchers have

Updated on: July 05,2024 0

New class of cancer mutations discovered in so-called 'junk' DNA

byGarvan Institute of Medical ResearchVisualized DNA damage (green) in human breast cancer cells (blue). Credit: Garvan InstituteUsing artificial intelligence, Garvan Institute researchers have

Updated on:July 05,2024 0

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on: May 21,2024 6

New study reveals an unexpected survival mechanism of a subset of cancer cells

by Instituto de Medicina MolecularMetaphase chromosomes from ALT cancer cells (U2OS osteosarcoma cell line) depleted for FANCM. Telomeric DNA is in green, chromosomal DNA is in red. The arrowheads poi

Updated on:May 21,2024 6

How the scars of demolished brain tumors seed relapse

byLudwig Cancer ResearchGraphical abstract. Credit:Cancer Cell(2024). DOI: 10.1016/j.ccell.2024.08.012A Ludwig Cancer Research study has discovered that recurrent tumors of the aggre

Updated on: September 30,2024 0

How the scars of demolished brain tumors seed relapse

byLudwig Cancer ResearchGraphical abstract. Credit:Cancer Cell(2024). DOI: 10.1016/j.ccell.2024.08.012A Ludwig Cancer Research study has discovered that recurrent tumors of the aggre

Updated on:September 30,2024 0

New genetic testing pathways could ensure patients get personalized BRCA-linked cancer treatments

byInstitute of Cancer ResearchThe BRCA-DIRECT Pathway. Credit:British Journal of Cancer(2024). DOI: 10.1038/s41416-024-02832-2Scientists have developed a new clinical pathway for tes

Updated on: October 24,2024 0

New genetic testing pathways could ensure patients get personalized BRCA-linked cancer treatments

byInstitute of Cancer ResearchThe BRCA-DIRECT Pathway. Credit:British Journal of Cancer(2024). DOI: 10.1038/s41416-024-02832-2Scientists have developed a new clinical pathway for tes

Updated on:October 24,2024 0

Study shows how cancer gene tricks immune cells

by Krista Conger,Stanford UniversityMYC regulated St6galnac4 promotes display of the glycan disialyl-T. (A) Murine T-ALL cell surface sialic acids were quantified at various time points after do

Updated on: February 20,2024 10

Study shows how cancer gene tricks immune cells

by Krista Conger,Stanford UniversityMYC regulated St6galnac4 promotes display of the glycan disialyl-T. (A) Murine T-ALL cell surface sialic acids were quantified at various time points after do

Updated on:February 20,2024 10

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on: April 28,2024 0

Researchers identify protein that controls CAR T cell longevity

byChildren's Hospital of PhiladelphiaLike a lightbulb, CAR T cells designed to kill cancer often burn out due to exhaustion and poor persistence. Doan et al. discovered that a transcription

Updated on:April 28,2024 0

Fred Hutch researchers engineer complex immunotherapy that may target relapsing leukemia

by Fred Hutchinson Cancer Research CenterDr. Marie Bleakley, a pediatric oncologist and researcher at Fred Hutch, is advancing a new approach to genetically engineer T cells. Credit: Fred HutchOc

Updated on: March 06,2024 17

Fred Hutch researchers engineer complex immunotherapy that may target relapsing leukemia

by Fred Hutchinson Cancer Research CenterDr. Marie Bleakley, a pediatric oncologist and researcher at Fred Hutch, is advancing a new approach to genetically engineer T cells. Credit: Fred HutchOc

Updated on:March 06,2024 17

Cancer patients facing housing instability show greater risk of mortality

byUniversity of California - San DiegoThe study was led by Matthew P. Banegas, PhD, an associate professor at UC San Diego School of Medicine and co-director of the Center for Health Equity Educ

Updated on: January 02,2024 9

Cancer patients facing housing instability show greater risk of mortality

byUniversity of California - San DiegoThe study was led by Matthew P. Banegas, PhD, an associate professor at UC San Diego School of Medicine and co-director of the Center for Health Equity Educ

Updated on:January 02,2024 9

Metalloimmunotherapy: Combination of cisplatin and STING agonist into one molecule boosts cancer immune response

by Science China PressSchematic illustration of the construction of conjugates I and II. Schematic illustration of the combinational effects on tumors of the PtIV-MSA-2 conjugates. The PtIV-MSA-2

Updated on: March 30,2024 0

Metalloimmunotherapy: Combination of cisplatin and STING agonist into one molecule boosts cancer immune response

by Science China PressSchematic illustration of the construction of conjugates I and II. Schematic illustration of the combinational effects on tumors of the PtIV-MSA-2 conjugates. The PtIV-MSA-2

Updated on:March 30,2024 0

Study reveals proton beam therapy may shorten breast cancer treatment

by Mayo ClinicCredit: Mayo ClinicIn a randomized trial, published inThe Lancet Oncology,Mayo Clinic Comprehensive Cancer Center researchers uncover evidence supporting a shorter treat

Updated on: January 30,2024 16

Study reveals proton beam therapy may shorten breast cancer treatment

by Mayo ClinicCredit: Mayo ClinicIn a randomized trial, published inThe Lancet Oncology,Mayo Clinic Comprehensive Cancer Center researchers uncover evidence supporting a shorter treat

Updated on:January 30,2024 16