Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Updated on: January 10,2024

Existing cancer drug ponatinib could be repurposed to fight certain aggressive cancers

byNanyang Technological UniversitySchematic summary of mechanisms of action of ponatinib in ALT cells. Ponatinib disrupts alternative lengthening of telomeres mechanisms by inducing telomeric C-

Updated on:January 10,2024

Could that breast pain be cancer? When to get a mammogram

byPennsylvania State UniversityCredit: Unsplash/CC0 Public DomainIf you've ever felt pain, tenderness and tightness—maybe even a sharp, stabbing sensation—in your breasts, it's hard not

Updated on: January 02,2024

Could that breast pain be cancer? When to get a mammogram

byPennsylvania State UniversityCredit: Unsplash/CC0 Public DomainIf you've ever felt pain, tenderness and tightness—maybe even a sharp, stabbing sensation—in your breasts, it's hard not

Updated on:January 02,2024

Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on: January 26,2024

Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on:January 26,2024

Treatment strategies for adenoid cystic carcinoma of the head and neck

by Impact Journals LLCCT-scan in a coronal section showing an adenoid cystic carcinoma as an inhomogeneous mass in the rightmaxillary sinus with infiltration of neighboring structures. Credit: 2023 Du

Updated on: January 07,2024

Treatment strategies for adenoid cystic carcinoma of the head and neck

by Impact Journals LLCCT-scan in a coronal section showing an adenoid cystic carcinoma as an inhomogeneous mass in the rightmaxillary sinus with infiltration of neighboring structures. Credit: 2023 Du

Updated on:January 07,2024

Targeting ABC transporters in pancreatic ductal carcinoma—past, present, or future?

by Impact Journals LLCRole for ABCB1 in PDAC chemoresistance. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28597A new editorial paper titled "Targeting ABC transporters in PDAC—p

Updated on: July 11,2024

Targeting ABC transporters in pancreatic ductal carcinoma—past, present, or future?

by Impact Journals LLCRole for ABCB1 in PDAC chemoresistance. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28597A new editorial paper titled "Targeting ABC transporters in PDAC—p

Updated on:July 11,2024

Gene interactions classify bowel tumors for personalized medicine

byeLifeFlowchart of the interaction-perturbation-based program. As an example, the background network consists of six genes and five interactions. There were three normal samples (yellow) and th

Updated on: December 25,2023

Gene interactions classify bowel tumors for personalized medicine

byeLifeFlowchart of the interaction-perturbation-based program. As an example, the background network consists of six genes and five interactions. There were three normal samples (yellow) and th

Updated on:December 25,2023

Simple low-dose aspirin may boost ovarian cancer survival

by QIMR BerghoferCredit: QIMRNew QIMR Berghofer research has found that low-dose aspirin may improve ovarian cancer survival.The study followed more than 900 Australian women newly-diagnosed with&nbsp

Updated on: December 26,2023

Simple low-dose aspirin may boost ovarian cancer survival

by QIMR BerghoferCredit: QIMRNew QIMR Berghofer research has found that low-dose aspirin may improve ovarian cancer survival.The study followed more than 900 Australian women newly-diagnosed with&nbsp

Updated on:December 26,2023

Gastroesophageal reflux disease causally linked to lung cancer

by Elana GotkineGastroesophageal reflux disease (GERD) is causally associated with lung cancer risk, according to a study published online Dec. 8 inCancer Medicine.Lin Li, from The Second Affili

Updated on: January 10,2024

Gastroesophageal reflux disease causally linked to lung cancer

by Elana GotkineGastroesophageal reflux disease (GERD) is causally associated with lung cancer risk, according to a study published online Dec. 8 inCancer Medicine.Lin Li, from The Second Affili

Updated on:January 10,2024

How sound waves trigger immune responses to cancer in mice

byUniversity of MichiganHistotripsy ablation is followed by infiltration of innate and adaptive immune cell populations. Mice bearing bilateral B16F10 tumors were treated with unilateral sham (c

Updated on: January 04,2024

How sound waves trigger immune responses to cancer in mice

byUniversity of MichiganHistotripsy ablation is followed by infiltration of innate and adaptive immune cell populations. Mice bearing bilateral B16F10 tumors were treated with unilateral sham (c

Updated on:January 04,2024

Study shows promise of new anti-KRAS drug for pancreatic cancer

by Perelman School of Medicine at the University of PennsylvaniaMRTX1133 reduces metastatic burden in a tail vein model. (A) Representative brightfield images of lungs from vehicle and MRTX1133 (

Updated on: January 30,2024

Study shows promise of new anti-KRAS drug for pancreatic cancer

by Perelman School of Medicine at the University of PennsylvaniaMRTX1133 reduces metastatic burden in a tail vein model. (A) Representative brightfield images of lungs from vehicle and MRTX1133 (

Updated on:January 30,2024

Researchers make unexpected discovery in how pancreatic cancer spreads

by Alison Satake,Mayo ClinicCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113042How cancer spreads or metastasizes is a big question for cancer researchers and patients. Mayo

Updated on: December 30,2023

Researchers make unexpected discovery in how pancreatic cancer spreads

by Alison Satake,Mayo ClinicCredit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113042How cancer spreads or metastasizes is a big question for cancer researchers and patients. Mayo

Updated on:December 30,2023

Gene and cell therapies to combat pancreatic cancer

byMary Ann Liebert, IncGTMP clinical trials for pancreatic cancer depending on phase and trial status. Source: Clinical trial.gov. GTMPs, gene therapy medicinal products. Credit:Human Gene

Updated on: December 25,2023

Gene and cell therapies to combat pancreatic cancer

byMary Ann Liebert, IncGTMP clinical trials for pancreatic cancer depending on phase and trial status. Source: Clinical trial.gov. GTMPs, gene therapy medicinal products. Credit:Human Gene

Updated on:December 25,2023