New cancer immunotherapy approach turns human cells into tiny anti-tumor drug factories

by University of California - San DiegoUC San Diego School of Medicine researchers developed a method to use B cells to manufacture and secrete microRNA-containing vesicles and showed they can in

Updated on: March 12,2024 13

New cancer immunotherapy approach turns human cells into tiny anti-tumor drug factories

by University of California - San DiegoUC San Diego School of Medicine researchers developed a method to use B cells to manufacture and secrete microRNA-containing vesicles and showed they can in

Updated on:March 12,2024 13

Pancreatic cancer vaccine plus immunotherapy and antibody spark immune system response in pancreatic cancers

by Johns Hopkins University School of MedicineJ1568 study treatment schema.Eligible patients with clinically resectable PDA received the first priming study treatment Cy-GVAX-based therapy (alone

Updated on: January 30,2024 16

Pancreatic cancer vaccine plus immunotherapy and antibody spark immune system response in pancreatic cancers

by Johns Hopkins University School of MedicineJ1568 study treatment schema.Eligible patients with clinically resectable PDA received the first priming study treatment Cy-GVAX-based therapy (alone

Updated on:January 30,2024 16

How tumors mutate their way out of a crisis—and become drug resistant in the process

byWeizmann Institute of ScienceHuman lung cancer cells under the microscope, before (left) and after (right) treatment with an anticancer drug, which causes DNA breaks (green) in the cell nuclei

Updated on: January 21,2024 18

How tumors mutate their way out of a crisis—and become drug resistant in the process

byWeizmann Institute of ScienceHuman lung cancer cells under the microscope, before (left) and after (right) treatment with an anticancer drug, which causes DNA breaks (green) in the cell nuclei

Updated on:January 21,2024 18

AI could improve diagnostic accuracy of breast dynamic contrast-enhanced magnetic resonance imaging

A deep learning (DL) system could improve the diagnostic accuracy of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of breast tissue for detecting breast cancer, according to a study p

Updated on: January 02,2024 9

AI could improve diagnostic accuracy of breast dynamic contrast-enhanced magnetic resonance imaging

A deep learning (DL) system could improve the diagnostic accuracy of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of breast tissue for detecting breast cancer, according to a study p

Updated on:January 02,2024 9

ACE inhibitor not protective against heart damage from chemotherapy

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainPatients who took an angiotensin-converting enzyme (ACE) inhibitor while undergoing cancer treatment with high-dose anthracyclin

Updated on: April 28,2024 0

ACE inhibitor not protective against heart damage from chemotherapy

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainPatients who took an angiotensin-converting enzyme (ACE) inhibitor while undergoing cancer treatment with high-dose anthracyclin

Updated on:April 28,2024 0

Novel drug shows early promise in treating multiple myeloma

byPerelman School of Medicine at the University of PennsylvaniaMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0A first-of

Updated on: January 15,2024 20

Novel drug shows early promise in treating multiple myeloma

byPerelman School of Medicine at the University of PennsylvaniaMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0A first-of

Updated on:January 15,2024 20

Researchers develop human cell-based model to study small cell lung cancer

by Rockefeller University PressLung progenitors (green) form increased numbers of neuroendocrine cells (red) when both the RB gene and the NOTCH signaling pathway are inhibited. Credit: Chen&nbsp

Updated on: June 11,2024 6

Researchers develop human cell-based model to study small cell lung cancer

by Rockefeller University PressLung progenitors (green) form increased numbers of neuroendocrine cells (red) when both the RB gene and the NOTCH signaling pathway are inhibited. Credit: Chen&nbsp

Updated on:June 11,2024 6

Metallic ion Copper and Zinc regulate inflammation and cancer metabolism

Updated on: June 19,2024 0

Metallic ion Copper and Zinc regulate inflammation and cancer metabolism

Updated on:June 19,2024 0

A cell surface marker for identifying tumor-initiating cells in pancreatic cancer

by Kumamoto UniversityROR1 is a cell surface receptor that promotes hyperproliferation, metastasis, and relapse in PDAC when highly expressed. Suppressing ROR1 reduces PDAC growth. Credit: Masaya

Updated on: February 19,2024 15

A cell surface marker for identifying tumor-initiating cells in pancreatic cancer

by Kumamoto UniversityROR1 is a cell surface receptor that promotes hyperproliferation, metastasis, and relapse in PDAC when highly expressed. Suppressing ROR1 reduces PDAC growth. Credit: Masaya

Updated on:February 19,2024 15

Study discovers that tumor mutation burden predicts survival outcome

by Tom Wilemon,Vanderbilt University Medical CenterCredit: Pixabay/CC0 Public DomainThe expected course of a patient's cancer prognosis has traditionally been judged by its type, stage and m

Updated on: January 28,2024 19

Study discovers that tumor mutation burden predicts survival outcome

by Tom Wilemon,Vanderbilt University Medical CenterCredit: Pixabay/CC0 Public DomainThe expected course of a patient's cancer prognosis has traditionally been judged by its type, stage and m

Updated on:January 28,2024 19

Active surveillance feasible for low-risk thyroid cancer

Active surveillance may be a viable strategy for most diagnosed thyroid cancers, according to a study published online Sept. 15 inJAMA Oncology.Allen S. Ho, M.D., from Cedars-Sinai Medical Cente

Updated on: January 21,2024 10

Active surveillance feasible for low-risk thyroid cancer

Active surveillance may be a viable strategy for most diagnosed thyroid cancers, according to a study published online Sept. 15 inJAMA Oncology.Allen S. Ho, M.D., from Cedars-Sinai Medical Cente

Updated on:January 21,2024 10

Tumor heterogeneity and immune-evasive environment in malignant lymphoma at single-cell resolution

byUniversity of TsukubaTranscriptomic profile of T follicular helper cell lymphoma (TFHL) samples. Credit:Leukemia(2023). DOI: 10.1038/s41375-023-02093-7Researchers at the University

Updated on: January 26,2024 22

Tumor heterogeneity and immune-evasive environment in malignant lymphoma at single-cell resolution

byUniversity of TsukubaTranscriptomic profile of T follicular helper cell lymphoma (TFHL) samples. Credit:Leukemia(2023). DOI: 10.1038/s41375-023-02093-7Researchers at the University

Updated on:January 26,2024 22