Understanding the maturation of white blood cells to find new therapies against lymphoblastic leukemia

byJosep Carreras Leukaemia Research InstitutePax5 K198 acetylation regulates gene expression. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01995-7More than 400 people, 80%

Updated on: November 10,2024

Understanding the maturation of white blood cells to find new therapies against lymphoblastic leukemia

byJosep Carreras Leukaemia Research InstitutePax5 K198 acetylation regulates gene expression. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01995-7More than 400 people, 80%

Updated on:November 10,2024

Pediatric brain cancer is rare. A doctor explains why some kids are more vulnerable than others

by Wendy RudermanCredit: Unsplash/CC0 Public DomainThe odds that a doctor will diagnose your child with pediatric cancer are slim, and the chances of a brain cancer diagnosis are even smaller.Each yea

Updated on: January 11,2024

Pediatric brain cancer is rare. A doctor explains why some kids are more vulnerable than others

by Wendy RudermanCredit: Unsplash/CC0 Public DomainThe odds that a doctor will diagnose your child with pediatric cancer are slim, and the chances of a brain cancer diagnosis are even smaller.Each yea

Updated on:January 11,2024

Phase 1 study shows novel KRAS inhibitor well tolerated by patients with adenocarcinoma and non-small cell lung cancer

by International Association for the Study of Lung CancerLung CA seen on CXR. Credit:CC BY-SA 4.0James Heilman, MD/WikipediaA clinical trial testing the toxicity of a KRAS inhibitor demons

Updated on: March 14,2024

Phase 1 study shows novel KRAS inhibitor well tolerated by patients with adenocarcinoma and non-small cell lung cancer

by International Association for the Study of Lung CancerLung CA seen on CXR. Credit:CC BY-SA 4.0James Heilman, MD/WikipediaA clinical trial testing the toxicity of a KRAS inhibitor demons

Updated on:March 14,2024

Prenatal exposure to anti-nausea drug in '60s, '70s tied to increased risk of colorectal cancer

byUniversity of Texas Health Science Center at HoustonCredit: Pixabay/CC0 Public DomainPrenatal exposure to an anti-nausea drug commonly used in the 1960s and 1970s has been shown to increase ri

Updated on: December 28,2023

Prenatal exposure to anti-nausea drug in '60s, '70s tied to increased risk of colorectal cancer

byUniversity of Texas Health Science Center at HoustonCredit: Pixabay/CC0 Public DomainPrenatal exposure to an anti-nausea drug commonly used in the 1960s and 1970s has been shown to increase ri

Updated on:December 28,2023

​ Vigilant monitoring is needed to manage cardiac risks in patients using antipsychotics, doctors say

by ElsevierCredit: Unsplash/CC0 Public DomainThe use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death

Updated on: May 06,2024

​ Vigilant monitoring is needed to manage cardiac risks in patients using antipsychotics, doctors say

by ElsevierCredit: Unsplash/CC0 Public DomainThe use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death

Updated on:May 06,2024

Magrolimab plus azacitidine results in promising activity in higher-risk MDS patients

byH. Lee Moffitt Cancer Center & Research InstituteHemoglobin changes from baseline over time on treatment with magrolimab + azacitidine in patients with HR-MDS (N = 95). Data shown are medi

Updated on: December 28,2023

Magrolimab plus azacitidine results in promising activity in higher-risk MDS patients

byH. Lee Moffitt Cancer Center & Research InstituteHemoglobin changes from baseline over time on treatment with magrolimab + azacitidine in patients with HR-MDS (N = 95). Data shown are medi

Updated on:December 28,2023

Study outlines opportunities to achieve Cancer Moonshot goal of reducing cancer death rates

by National Institutes of HealthTo achieve the Cancer Moonshot goal, cancer death rates must decline faster. Credit: Shiels M, et al.Cancer Discovery, 2023Researchers from the National Inst

Updated on: February 18,2024

Study outlines opportunities to achieve Cancer Moonshot goal of reducing cancer death rates

by National Institutes of HealthTo achieve the Cancer Moonshot goal, cancer death rates must decline faster. Credit: Shiels M, et al.Cancer Discovery, 2023Researchers from the National Inst

Updated on:February 18,2024

Researchers develop human cell-based model to study small cell lung cancer

by Rockefeller University PressLung progenitors (green) form increased numbers of neuroendocrine cells (red) when both the RB gene and the NOTCH signaling pathway are inhibited. Credit: Chen&nbsp

Updated on: June 11,2024

Researchers develop human cell-based model to study small cell lung cancer

by Rockefeller University PressLung progenitors (green) form increased numbers of neuroendocrine cells (red) when both the RB gene and the NOTCH signaling pathway are inhibited. Credit: Chen&nbsp

Updated on:June 11,2024

Immunotherapy for HPV+ head and neck cancer: Awakening the force within

by Emory UniversityCredit: Pixabay/CC0 Public DomainA new study from scientists at Emory Vaccine Center and Winship Cancer Institute of Emory University reports that the immune cells that are the

Updated on: April 16,2024

Immunotherapy for HPV+ head and neck cancer: Awakening the force within

by Emory UniversityCredit: Pixabay/CC0 Public DomainA new study from scientists at Emory Vaccine Center and Winship Cancer Institute of Emory University reports that the immune cells that are the

Updated on:April 16,2024

A new approach for bolstering the ability of T cells to fight cancer

by Monash UniversityCredit: CC0 Public DomainA collaborative study led by the Monash Biomedicine Discovery Institute (BDI) has discovered a new immune checkpoint that may be exploited for cancer

Updated on: March 25,2024

A new approach for bolstering the ability of T cells to fight cancer

by Monash UniversityCredit: CC0 Public DomainA collaborative study led by the Monash Biomedicine Discovery Institute (BDI) has discovered a new immune checkpoint that may be exploited for cancer

Updated on:March 25,2024

Study shows promise of new anti-KRAS drug for pancreatic cancer

by Perelman School of Medicine at the University of PennsylvaniaMRTX1133 reduces metastatic burden in a tail vein model. (A) Representative brightfield images of lungs from vehicle and MRTX1133 (

Updated on: January 30,2024

Study shows promise of new anti-KRAS drug for pancreatic cancer

by Perelman School of Medicine at the University of PennsylvaniaMRTX1133 reduces metastatic burden in a tail vein model. (A) Representative brightfield images of lungs from vehicle and MRTX1133 (

Updated on:January 30,2024

Mitochondrial protein synthesis identified as a potential therapeutic target in lymphoma

byUniversity of OxfordSpleen sections from mito-QC mice immunized with SRBC and analyzed on day 12. Scale bar, 50 μm. Representative of three independent experiments. Credit:Nature Immunol

Updated on: January 10,2024

Mitochondrial protein synthesis identified as a potential therapeutic target in lymphoma

byUniversity of OxfordSpleen sections from mito-QC mice immunized with SRBC and analyzed on day 12. Scale bar, 50 μm. Representative of three independent experiments. Credit:Nature Immunol

Updated on:January 10,2024