Understanding the maturation of white blood cells to find new therapies against lymphoblastic leukemia

byJosep Carreras Leukaemia Research InstitutePax5 K198 acetylation regulates gene expression. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01995-7More than 400 people, 80%

Updated on: November 10,2024

Understanding the maturation of white blood cells to find new therapies against lymphoblastic leukemia

byJosep Carreras Leukaemia Research InstitutePax5 K198 acetylation regulates gene expression. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01995-7More than 400 people, 80%

Updated on:November 10,2024

New genetic test for pancreatic cancer outperforms current guidelines

by University of PittsburghCredit: Pixabay/CC0 Public DomainA molecular test called PancreaSeq accurately classifies pancreatic cysts as potentially cancerous or benign, according to a large, mul

Updated on: January 30,2024

New genetic test for pancreatic cancer outperforms current guidelines

by University of PittsburghCredit: Pixabay/CC0 Public DomainA molecular test called PancreaSeq accurately classifies pancreatic cysts as potentially cancerous or benign, according to a large, mul

Updated on:January 30,2024

First-in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses

by Perelman School of Medicine at the University of PennsylvaniaSafety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with

Updated on: January 26,2024

First-in-human clinical trial of CAR T cell therapy with new binding mechanism shows promising early responses

by Perelman School of Medicine at the University of PennsylvaniaSafety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with

Updated on:January 26,2024

Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on: January 26,2024

Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on:January 26,2024

Cytokine mediates obesity-related factors linked to colorectal cancer

byMary Ann Liebert, IncCredit: Mary Ann Liebert, Inc., publishersA new study describes the mechanistic relationship between the cytokine interleukin-1ß, (IL-1ß) and obesity, showing that when IL

Updated on: December 18,2023

Cytokine mediates obesity-related factors linked to colorectal cancer

byMary Ann Liebert, IncCredit: Mary Ann Liebert, Inc., publishersA new study describes the mechanistic relationship between the cytokine interleukin-1ß, (IL-1ß) and obesity, showing that when IL

Updated on:December 18,2023

Surge in syphilis cases leads some providers to ration penicillin

by Catherine Sweeney, WPLN, KFF Health NewsCredit: Pixabay/CC0 Public DomainWhen Stephen Miller left his primary care practice to work in public health a little under two years ago, he said, he was sh

Updated on: May 07,2024

Surge in syphilis cases leads some providers to ration penicillin

by Catherine Sweeney, WPLN, KFF Health NewsCredit: Pixabay/CC0 Public DomainWhen Stephen Miller left his primary care practice to work in public health a little under two years ago, he said, he was sh

Updated on:May 07,2024

Simple low-dose aspirin may boost ovarian cancer survival

by QIMR BerghoferCredit: QIMRNew QIMR Berghofer research has found that low-dose aspirin may improve ovarian cancer survival.The study followed more than 900 Australian women newly-diagnosed with&nbsp

Updated on: December 26,2023

Simple low-dose aspirin may boost ovarian cancer survival

by QIMR BerghoferCredit: QIMRNew QIMR Berghofer research has found that low-dose aspirin may improve ovarian cancer survival.The study followed more than 900 Australian women newly-diagnosed with&nbsp

Updated on:December 26,2023

Researchers demonstrate that a machine learning model predicts oxaliplatin benefit

by NRG OncologyCredit: Unsplash/CC0 Public DomainThe current standard of care for treating patients with stage 3 colon cancer is to use adjuvant therapy with FOLFOX, a combination of the drugs fluorou

Updated on: May 16,2024

Researchers demonstrate that a machine learning model predicts oxaliplatin benefit

by NRG OncologyCredit: Unsplash/CC0 Public DomainThe current standard of care for treating patients with stage 3 colon cancer is to use adjuvant therapy with FOLFOX, a combination of the drugs fluorou

Updated on:May 16,2024

Gastroesophageal reflux disease causally linked to lung cancer

by Elana GotkineGastroesophageal reflux disease (GERD) is causally associated with lung cancer risk, according to a study published online Dec. 8 inCancer Medicine.Lin Li, from The Second Affili

Updated on: January 10,2024

Gastroesophageal reflux disease causally linked to lung cancer

by Elana GotkineGastroesophageal reflux disease (GERD) is causally associated with lung cancer risk, according to a study published online Dec. 8 inCancer Medicine.Lin Li, from The Second Affili

Updated on:January 10,2024

Researchers uncover on/off switch for breast cancer metastasis

by Rebecca McClellan,Stanford UniversitySongnan Wang (left) and Lingyin Li (right) found that a protein called ENPP1 acts as an on/off switch for breast cancer metastases. High protein levels le

Updated on: December 28,2023

Researchers uncover on/off switch for breast cancer metastasis

by Rebecca McClellan,Stanford UniversitySongnan Wang (left) and Lingyin Li (right) found that a protein called ENPP1 acts as an on/off switch for breast cancer metastases. High protein levels le

Updated on:December 28,2023

Researchers discover the role of RNF114B, a key gene in the progression and treatment of lung adenocarcinoma

byUniversitat Pompeu Fabra - BarcelonaA mouse fibroblast with altered RNF144B expression divides without correctly grouping chromosomes (stained blue), resulting in aberrant cells. Credit: UPFRe

Updated on: July 09,2024

Researchers discover the role of RNF114B, a key gene in the progression and treatment of lung adenocarcinoma

byUniversitat Pompeu Fabra - BarcelonaA mouse fibroblast with altered RNF144B expression divides without correctly grouping chromosomes (stained blue), resulting in aberrant cells. Credit: UPFRe

Updated on:July 09,2024

Treatment strategies for adenoid cystic carcinoma of the head and neck

by Impact Journals LLCCT-scan in a coronal section showing an adenoid cystic carcinoma as an inhomogeneous mass in the rightmaxillary sinus with infiltration of neighboring structures. Credit: 2023 Du

Updated on: January 07,2024

Treatment strategies for adenoid cystic carcinoma of the head and neck

by Impact Journals LLCCT-scan in a coronal section showing an adenoid cystic carcinoma as an inhomogeneous mass in the rightmaxillary sinus with infiltration of neighboring structures. Credit: 2023 Du

Updated on:January 07,2024