Phase 1 study shows novel KRAS inhibitor well tolerated by patients with adenocarcinoma and non-small cell lung cancer

by International Association for the Study of Lung CancerLung CA seen on CXR. Credit:CC BY-SA 4.0James Heilman, MD/WikipediaA clinical trial testing the toxicity of a KRAS inhibitor demons

Updated on: March 14,2024

Phase 1 study shows novel KRAS inhibitor well tolerated by patients with adenocarcinoma and non-small cell lung cancer

by International Association for the Study of Lung CancerLung CA seen on CXR. Credit:CC BY-SA 4.0James Heilman, MD/WikipediaA clinical trial testing the toxicity of a KRAS inhibitor demons

Updated on:March 14,2024

Study shows promise of new anti-KRAS drug for pancreatic cancer

by Perelman School of Medicine at the University of PennsylvaniaMRTX1133 reduces metastatic burden in a tail vein model. (A) Representative brightfield images of lungs from vehicle and MRTX1133 (

Updated on: January 30,2024

Study shows promise of new anti-KRAS drug for pancreatic cancer

by Perelman School of Medicine at the University of PennsylvaniaMRTX1133 reduces metastatic burden in a tail vein model. (A) Representative brightfield images of lungs from vehicle and MRTX1133 (

Updated on:January 30,2024

Proposed cancer treatment may boost lung cancer stem cells, study warns

by Children's Hospital BostonKiller T cells surround a cancer cell. Credit: NIHEpigenetic therapies—targeting enzymes that alter what genes are turned on or off in a cell—are of growing inter

Updated on: June 28,2024

Proposed cancer treatment may boost lung cancer stem cells, study warns

by Children's Hospital BostonKiller T cells surround a cancer cell. Credit: NIHEpigenetic therapies—targeting enzymes that alter what genes are turned on or off in a cell—are of growing inter

Updated on:June 28,2024

Combining neurologic and blood pressure drugs reduces breast tumor development in mice

byGeorgetown University Medical CenterCancer cell during cell division. Credit: National Institutes of HealthAdding a medication used to treat epilepsy, bipolar disorder and migraines to a blood

Updated on: December 22,2023

Combining neurologic and blood pressure drugs reduces breast tumor development in mice

byGeorgetown University Medical CenterCancer cell during cell division. Credit: National Institutes of HealthAdding a medication used to treat epilepsy, bipolar disorder and migraines to a blood

Updated on:December 22,2023

Permanent hair dye and straighteners may increase breast cancer risk

by National Institutes of HealthThe study found that women who use permanent hair dye and chemical hair straighteners have a higher risk of developing breast cancer than women who don't use t

Updated on: May 11,2024

Permanent hair dye and straighteners may increase breast cancer risk

by National Institutes of HealthThe study found that women who use permanent hair dye and chemical hair straighteners have a higher risk of developing breast cancer than women who don't use t

Updated on:May 11,2024

Study outlines opportunities to achieve Cancer Moonshot goal of reducing cancer death rates

by National Institutes of HealthTo achieve the Cancer Moonshot goal, cancer death rates must decline faster. Credit: Shiels M, et al.Cancer Discovery, 2023Researchers from the National Inst

Updated on: February 18,2024

Study outlines opportunities to achieve Cancer Moonshot goal of reducing cancer death rates

by National Institutes of HealthTo achieve the Cancer Moonshot goal, cancer death rates must decline faster. Credit: Shiels M, et al.Cancer Discovery, 2023Researchers from the National Inst

Updated on:February 18,2024

Prenatal exposure to anti-nausea drug in '60s, '70s tied to increased risk of colorectal cancer

byUniversity of Texas Health Science Center at HoustonCredit: Pixabay/CC0 Public DomainPrenatal exposure to an anti-nausea drug commonly used in the 1960s and 1970s has been shown to increase ri

Updated on: December 28,2023

Prenatal exposure to anti-nausea drug in '60s, '70s tied to increased risk of colorectal cancer

byUniversity of Texas Health Science Center at HoustonCredit: Pixabay/CC0 Public DomainPrenatal exposure to an anti-nausea drug commonly used in the 1960s and 1970s has been shown to increase ri

Updated on:December 28,2023

Trial shows promise for new antibody cancer treatment

byKing's College LondonMechanism of cytotoxicity mediated by MOv18 IgE. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-39679-9The first ever clinical trial of a new

Updated on: January 04,2024

Trial shows promise for new antibody cancer treatment

byKing's College LondonMechanism of cytotoxicity mediated by MOv18 IgE. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-39679-9The first ever clinical trial of a new

Updated on:January 04,2024

New genetic test for pancreatic cancer outperforms current guidelines

by University of PittsburghCredit: Pixabay/CC0 Public DomainA molecular test called PancreaSeq accurately classifies pancreatic cysts as potentially cancerous or benign, according to a large, mul

Updated on: January 30,2024

New genetic test for pancreatic cancer outperforms current guidelines

by University of PittsburghCredit: Pixabay/CC0 Public DomainA molecular test called PancreaSeq accurately classifies pancreatic cysts as potentially cancerous or benign, according to a large, mul

Updated on:January 30,2024

Avelumab plus axitinib significantly improve progression-free survival in untreated renal cell carcinoma

byEuropean Society for Medical OncologyCredit: CC0 Public DomainA combination of the immune checkpoint blocker, avelumab, plus the tyrosine kinase inhibitor (TKI), axitinib, significantly improv

Updated on: December 18,2023

Avelumab plus axitinib significantly improve progression-free survival in untreated renal cell carcinoma

byEuropean Society for Medical OncologyCredit: CC0 Public DomainA combination of the immune checkpoint blocker, avelumab, plus the tyrosine kinase inhibitor (TKI), axitinib, significantly improv

Updated on:December 18,2023

Researchers develop gel to deliver cancer drugs for solid tumors

byMass General BrighamCredit: Pixabay/CC0 Public DomainIntratumoral therapy—in which cancer drugs are injected directly into tumors—is a promising treatment option for solid cancers but has show

Updated on: January 03,2024

Researchers develop gel to deliver cancer drugs for solid tumors

byMass General BrighamCredit: Pixabay/CC0 Public DomainIntratumoral therapy—in which cancer drugs are injected directly into tumors—is a promising treatment option for solid cancers but has show

Updated on:January 03,2024

Mitochondrial protein synthesis identified as a potential therapeutic target in lymphoma

byUniversity of OxfordSpleen sections from mito-QC mice immunized with SRBC and analyzed on day 12. Scale bar, 50 μm. Representative of three independent experiments. Credit:Nature Immunol

Updated on: January 10,2024

Mitochondrial protein synthesis identified as a potential therapeutic target in lymphoma

byUniversity of OxfordSpleen sections from mito-QC mice immunized with SRBC and analyzed on day 12. Scale bar, 50 μm. Representative of three independent experiments. Credit:Nature Immunol

Updated on:January 10,2024