Trial demonstrates firmonertinib is a potential therapy for patients with NSCLC with EGFR PACC mutations

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe tyrosine kinase inhibitor firmonertinib showed promising efficacy in patients with non-small cell lung can

Updated on: September 27,2024

Trial demonstrates firmonertinib is a potential therapy for patients with NSCLC with EGFR PACC mutations

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe tyrosine kinase inhibitor firmonertinib showed promising efficacy in patients with non-small cell lung can

Updated on:September 27,2024

Study findings provide new insight into how breast cancer evolves

by Kyoto UniversityThe der(1;16) translocation-positive breast cancer originated from a single cell around puberty. This cell repeatedly underwent cell division and expanded until it developed in

Updated on: February 20,2024

Study findings provide new insight into how breast cancer evolves

by Kyoto UniversityThe der(1;16) translocation-positive breast cancer originated from a single cell around puberty. This cell repeatedly underwent cell division and expanded until it developed in

Updated on:February 20,2024

Nirogacestat, a new desmoid tumor treatment, found to improve outcomes for people with sarcoma

byMemorial Sloan Kettering Cancer CenterCredit:New England Journal of Medicine(2023). DOI: 10.1056/NEJMoa2210140When Dana Avellino, now 36, first noticed a lump near her groin in the

Updated on: January 11,2024

Nirogacestat, a new desmoid tumor treatment, found to improve outcomes for people with sarcoma

byMemorial Sloan Kettering Cancer CenterCredit:New England Journal of Medicine(2023). DOI: 10.1056/NEJMoa2210140When Dana Avellino, now 36, first noticed a lump near her groin in the

Updated on:January 11,2024

Study offers new insights into earliest stages of brain tumor development

by University of PlymouthCredit:EMBO Reports(2024). DOI: 10.1038/s44319-023-00017-1Scientists working to better understand and find a cure for brain tumors have made progress in ident

Updated on: March 20,2024

Study offers new insights into earliest stages of brain tumor development

by University of PlymouthCredit:EMBO Reports(2024). DOI: 10.1038/s44319-023-00017-1Scientists working to better understand and find a cure for brain tumors have made progress in ident

Updated on:March 20,2024

Researchers devise novel solution to preventing relapse after CAR T-cell therapy

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainEven as they have revolutionized the treatment of certain forms of cancer, CAR T-cell therapies have been shadowed by a significant

Updated on: August 28,2024

Researchers devise novel solution to preventing relapse after CAR T-cell therapy

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainEven as they have revolutionized the treatment of certain forms of cancer, CAR T-cell therapies have been shadowed by a significant

Updated on:August 28,2024

New therapeutic strategy for metastatic prostate cancer patients resistant to standard treatment

FEBRUARY 2, 2024 Editors' notesby Germans Trias i Pujol Research InstituteCredit: Unsplash/CC0 Public DomainA team of researchers from the Badalona Applied Research Group in Oncology (B·ARGO) and

Updated on: March 15,2024

New therapeutic strategy for metastatic prostate cancer patients resistant to standard treatment

FEBRUARY 2, 2024 Editors' notesby Germans Trias i Pujol Research InstituteCredit: Unsplash/CC0 Public DomainA team of researchers from the Badalona Applied Research Group in Oncology (B·ARGO) and

Updated on:March 15,2024

How do we know health screening programs work?

by Christian Yates,The ConversationLead-time bias can appear to make a treatment more effective than it actually is, if the perceived post-diagnosis survival time increases while the course of d

Updated on: January 10,2024

How do we know health screening programs work?

by Christian Yates,The ConversationLead-time bias can appear to make a treatment more effective than it actually is, if the perceived post-diagnosis survival time increases while the course of d

Updated on:January 10,2024

Heterogeneity of liver cancer cells helps explain tumor progression in patients

byThe Mount Sinai HospitalCredit: CC0 Public DomainMany liver cancer tumors contain a highly diverse set of cells, a phenomenon known as intra-tumor heterogeneity that can significantly affect t

Updated on: December 20,2023

Heterogeneity of liver cancer cells helps explain tumor progression in patients

byThe Mount Sinai HospitalCredit: CC0 Public DomainMany liver cancer tumors contain a highly diverse set of cells, a phenomenon known as intra-tumor heterogeneity that can significantly affect t

Updated on:December 20,2023

Study finds novel role of BRCA1 in tumor suppression

by Steven Lee,University of Texas Health Science Center at San AntonioSingle-molecule analysis of BRCA1–BARD1 in BLM- and EXO1-dependent resection. Credit:Nature(2024). DOI: 10.1038/

Updated on: November 11,2024

Study finds novel role of BRCA1 in tumor suppression

by Steven Lee,University of Texas Health Science Center at San AntonioSingle-molecule analysis of BRCA1–BARD1 in BLM- and EXO1-dependent resection. Credit:Nature(2024). DOI: 10.1038/

Updated on:November 11,2024

Researchers discover critical process for how breast cancer spreads in bones

by Brandi Wampler,University of Notre DameScientist Laurie Littlepage works with graduate student Ricardo Romero Moreno in her lab at the Harper Cancer Research Institute. Credit: Barbara Johnst

Updated on: June 19,2024

Researchers discover critical process for how breast cancer spreads in bones

by Brandi Wampler,University of Notre DameScientist Laurie Littlepage works with graduate student Ricardo Romero Moreno in her lab at the Harper Cancer Research Institute. Credit: Barbara Johnst

Updated on:June 19,2024

Risk model identifies metastatic cancer patients who may benefit from immune checkpoint inhibitors

byUniversity of Eastern FinlandSurvival of the patients according to the risk scores. Kaplan-Meier curves illustrating overall survival (OS) (a) and progression-free survival (PFS) (b) according

Updated on: January 25,2024

Risk model identifies metastatic cancer patients who may benefit from immune checkpoint inhibitors

byUniversity of Eastern FinlandSurvival of the patients according to the risk scores. Kaplan-Meier curves illustrating overall survival (OS) (a) and progression-free survival (PFS) (b) according

Updated on:January 25,2024

Existing drug shows promise treating most prevalent type of lung cancer

byUniversity of KentuckyCZT binds to SRC. A. CZT binding (dashed circle) to SRC. CZT binds near the C-terminal domain of SRC and may disrupt the inactive state by preventing phosphorylation on t

Updated on: January 10,2024

Existing drug shows promise treating most prevalent type of lung cancer

byUniversity of KentuckyCZT binds to SRC. A. CZT binding (dashed circle) to SRC. CZT binds near the C-terminal domain of SRC and may disrupt the inactive state by preventing phosphorylation on t

Updated on:January 10,2024