Genetic modifications improve the therapeutic efficacy of iPSC-derived CAR-T cells against solid tumors

by Kyoto UniversityThe CAR construct impacts the differentiation of CAR-iPSCs into T-cell lineages. a, Schematic presentation of the CAR constructs 19z, 1928z, 19bbz, 1928bbz and w/oED28z CAR (w/

Updated on: February 20,2024

Genetic modifications improve the therapeutic efficacy of iPSC-derived CAR-T cells against solid tumors

by Kyoto UniversityThe CAR construct impacts the differentiation of CAR-iPSCs into T-cell lineages. a, Schematic presentation of the CAR constructs 19z, 1928z, 19bbz, 1928bbz and w/oED28z CAR (w/

Updated on:February 20,2024

Enhanced melanoma vaccine offers improved survival for men

by University of VirginiaMel44 clinical trial design and long-term outcomes analysis. The Mel44 clinical trial was designed to evaluate immunologic and clinical outcomes after vaccination with ei

Updated on: March 30,2024

Enhanced melanoma vaccine offers improved survival for men

by University of VirginiaMel44 clinical trial design and long-term outcomes analysis. The Mel44 clinical trial was designed to evaluate immunologic and clinical outcomes after vaccination with ei

Updated on:March 30,2024

Low-cost, portable device can detect colorectal and prostate cancer in an hour

byUniversity of Texas at El PasoA team of researchers from The University of Texas at El Paso, led by Xiujun (James) Li, Ph.D., has created a low-cost, portable device that can detect colorectal

Updated on: November 11,2024

Low-cost, portable device can detect colorectal and prostate cancer in an hour

byUniversity of Texas at El PasoA team of researchers from The University of Texas at El Paso, led by Xiujun (James) Li, Ph.D., has created a low-cost, portable device that can detect colorectal

Updated on:November 11,2024

Global study predicts more than 50 percent rise in chemotherapy demand by 2040

byLancetCredit: CC0 Public DomainTo deliver optimal treatment by 2040, a significant expansion of the chemotherapy workforce is needed.Between 2018 and 2040, the number of patients requiri

Updated on: May 23,2024

Global study predicts more than 50 percent rise in chemotherapy demand by 2040

byLancetCredit: CC0 Public DomainTo deliver optimal treatment by 2040, a significant expansion of the chemotherapy workforce is needed.Between 2018 and 2040, the number of patients requiri

Updated on:May 23,2024

Convection-enhanced delivery of topotecan active in glioblastoma

by Elana GotkineA subcutaneously implanted, catheter-pump system capable of chronic convection-enhanced delivery (CED) of topotecan is well tolerated and active for patients with recurrent glioblastom

Updated on: January 30,2024

Convection-enhanced delivery of topotecan active in glioblastoma

by Elana GotkineA subcutaneously implanted, catheter-pump system capable of chronic convection-enhanced delivery (CED) of topotecan is well tolerated and active for patients with recurrent glioblastom

Updated on:January 30,2024

Natural killer cells may open lifesaving cancer treatements to more patients

by University of Central FloridaUCF College of Medicine cancer researcher Alicja Copik has just discovered a way to make that therapy viable to thousands by using the body's own natural kille

Updated on: April 01,2024

Natural killer cells may open lifesaving cancer treatements to more patients

by University of Central FloridaUCF College of Medicine cancer researcher Alicja Copik has just discovered a way to make that therapy viable to thousands by using the body's own natural kille

Updated on:April 01,2024

Lymphoma patients at high risk of infections after diagnosis

byUppsala UniversityGraphical abstract. Credit:HemaSphere(2024). DOI: 10.1002/hem3.121Every year, around 100 people are affected by mantle cell lymphoma. A study at Uppsala Universit

Updated on: July 09,2024

Lymphoma patients at high risk of infections after diagnosis

byUppsala UniversityGraphical abstract. Credit:HemaSphere(2024). DOI: 10.1002/hem3.121Every year, around 100 people are affected by mantle cell lymphoma. A study at Uppsala Universit

Updated on:July 09,2024

A possible way to reenergize T cells exhausted from fighting a tumor

by Bob Yirka , Medical XpressScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHAn international team of researchers has found a possible way to reenergize T cells exhauste

Updated on: March 26,2024

A possible way to reenergize T cells exhausted from fighting a tumor

by Bob Yirka , Medical XpressScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHAn international team of researchers has found a possible way to reenergize T cells exhauste

Updated on:March 26,2024

Blood cancer research points to new treatment for bone marrow cancer

byUniversity of VirginiaDeletion of IL-1R1 preferentially inhibits Jak2V617F mutant hematopoietic stem/progenitor cells.aA scheme on competitive BM transplantation approach to assess

Updated on: January 15,2024

Blood cancer research points to new treatment for bone marrow cancer

byUniversity of VirginiaDeletion of IL-1R1 preferentially inhibits Jak2V617F mutant hematopoietic stem/progenitor cells.aA scheme on competitive BM transplantation approach to assess

Updated on:January 15,2024

Premature death of autistic people in the UK investigated for the first time

by University College LondonCredit: Unsplash/CC0 Public DomainA new study led by University College London researchers confirms that autistic people experience a reduced life expectancy; however,

Updated on: May 11,2024

Premature death of autistic people in the UK investigated for the first time

by University College LondonCredit: Unsplash/CC0 Public DomainA new study led by University College London researchers confirms that autistic people experience a reduced life expectancy; however,

Updated on:May 11,2024

RNA nanoparticle therapy stops the spread of incurable bone marrow cancer, study finds

by Melissa Pappas, University of Pennsylvania School of Engineering and Applied ScienceCredit: Unsplash/CC0 Public DomainMultiple myeloma is an incurable bone marrow cancer that kills over 100,000 peo

Updated on: January 23,2024

RNA nanoparticle therapy stops the spread of incurable bone marrow cancer, study finds

by Melissa Pappas, University of Pennsylvania School of Engineering and Applied ScienceCredit: Unsplash/CC0 Public DomainMultiple myeloma is an incurable bone marrow cancer that kills over 100,000 peo

Updated on:January 23,2024

Cancer survivors see mostly positives in how they have changed

by Jeff Grabmeier,The Ohio State UniversityCredit: CC0 Public DomainTwo years after diagnosis, breast cancer survivors have four times more positive than negative thoughts about changes they exp

Updated on: March 12,2024

Cancer survivors see mostly positives in how they have changed

by Jeff Grabmeier,The Ohio State UniversityCredit: CC0 Public DomainTwo years after diagnosis, breast cancer survivors have four times more positive than negative thoughts about changes they exp

Updated on:March 12,2024