Tackling resistance to HIF2 drugs with an RNA-based therapy

byUT Southwestern Medical CenterDownregulation of HIF2α by ARO-HIF2 in patient tumor biopsies. Credit: Dr. Payal KapurExpected to be diagnosed in 2% of men and 1% of women in the U.S., kidney ca

Updated on: December 28,2023

Tackling resistance to HIF2 drugs with an RNA-based therapy

byUT Southwestern Medical CenterDownregulation of HIF2α by ARO-HIF2 in patient tumor biopsies. Credit: Dr. Payal KapurExpected to be diagnosed in 2% of men and 1% of women in the U.S., kidney ca

Updated on:December 28,2023

Key insights from statistical modeling of cancer patient life expectancy

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainWith the progress in treatment for most cancer types, there is a growing interest to understand the overall impact of a cancer diagnosis t

Updated on: April 06,2024

Key insights from statistical modeling of cancer patient life expectancy

by Karolinska InstitutetCredit: Pixabay/CC0 Public DomainWith the progress in treatment for most cancer types, there is a growing interest to understand the overall impact of a cancer diagnosis t

Updated on:April 06,2024

Scientists find way to starve breast cancer cells

by Jennifer Michalowski,Cold Spring Harbor LaboratoryWhen fast-growing breast cancer cells run out of glutamine, they turn to an alternative supply line. PHGDH (above, in green) is a key enzyme

Updated on: September 07,2024

Scientists find way to starve breast cancer cells

by Jennifer Michalowski,Cold Spring Harbor LaboratoryWhen fast-growing breast cancer cells run out of glutamine, they turn to an alternative supply line. PHGDH (above, in green) is a key enzyme

Updated on:September 07,2024

Researchers link cancer gene to Scottish island

byUniversity of EdinburghGrandparental ancestry of BRCA2 c.517-2A>G carriers in VIKING I. Credit:European Journal of Human Genetics(2024). DOI: 10.1038/s41431-024-01704-wPeople wi

Updated on: November 08,2024

Researchers link cancer gene to Scottish island

byUniversity of EdinburghGrandparental ancestry of BRCA2 c.517-2A>G carriers in VIKING I. Credit:European Journal of Human Genetics(2024). DOI: 10.1038/s41431-024-01704-wPeople wi

Updated on:November 08,2024

Scientists decode key mutation in many cancers, pointing to expanded role of RNA in human gene expression

byUniversity of ChicagoCredit: Unsplash/CC0 Public DomainInside every cell, inside every nucleus, your continued existence depends on an incredibly complicated dance. Proteins are constantly wra

Updated on: November 10,2024

Scientists decode key mutation in many cancers, pointing to expanded role of RNA in human gene expression

byUniversity of ChicagoCredit: Unsplash/CC0 Public DomainInside every cell, inside every nucleus, your continued existence depends on an incredibly complicated dance. Proteins are constantly wra

Updated on:November 10,2024

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on: February 20,2024

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on:February 20,2024

Many breast cancer survivors do not receive genetic testing, despite being eligible

by Nicole Fawcett,University of MichiganCredit: Unsplash/CC0 Public DomainAs cancer treatment and survivorship care relies more on understanding the genetic make-up of an individual's tumor,

Updated on: July 17,2024

Many breast cancer survivors do not receive genetic testing, despite being eligible

by Nicole Fawcett,University of MichiganCredit: Unsplash/CC0 Public DomainAs cancer treatment and survivorship care relies more on understanding the genetic make-up of an individual's tumor,

Updated on:July 17,2024

Proportion of cancers associated with excess body weight varies considerably by state

by American Cancer SocietyCredit: CC0 Public DomainA new study looking at the share of cancers related to obesity finds an at least 1.5-fold difference between states with the highest and lowest

Updated on: March 06,2024

Proportion of cancers associated with excess body weight varies considerably by state

by American Cancer SocietyCredit: CC0 Public DomainA new study looking at the share of cancers related to obesity finds an at least 1.5-fold difference between states with the highest and lowest

Updated on:March 06,2024

Innovations in cancer treatment through targeted bacterial vaccines

byScience China PressThe schematic illustrates how the nanovaccine induces robust anti-F. nucleatum immune responses that significantly improve the efficiency of chemotherapy and reduce cancer m

Updated on: September 10,2024

Innovations in cancer treatment through targeted bacterial vaccines

byScience China PressThe schematic illustrates how the nanovaccine induces robust anti-F. nucleatum immune responses that significantly improve the efficiency of chemotherapy and reduce cancer m

Updated on:September 10,2024

Race, income can determine blood cancer outcomes, studies show

by Ernie MundellIf someone is stricken with a blood cancer or life-threatening clot, they'll probably fare better if they are white and wealthy, three new studies show.The ongoing impact of patien

Updated on: January 22,2024

Race, income can determine blood cancer outcomes, studies show

by Ernie MundellIf someone is stricken with a blood cancer or life-threatening clot, they'll probably fare better if they are white and wealthy, three new studies show.The ongoing impact of patien

Updated on:January 22,2024

A new combination therapy regimen shows promising results for prostate cancer

by Huntsman Cancer InstituteCredit: CC0 Public DomainTALAPRO-2, a study led by Neeraj Agarwal, MD, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progress

Updated on: January 28,2024

A new combination therapy regimen shows promising results for prostate cancer

by Huntsman Cancer InstituteCredit: CC0 Public DomainTALAPRO-2, a study led by Neeraj Agarwal, MD, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progress

Updated on:January 28,2024

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall

Updated on: July 05,2024

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall

Updated on:July 05,2024