New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on: January 12,2024

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on:January 12,2024

Study: More aggressive treatments needed to improve 5-year survival rate for glioblastoma

by Joe Dangor,Mayo ClinicCredit: Mayo ClinicDespite improvements in median and short-term survival rates for patients with glioblastoma, the most common brain tumor in adults, the percentage of

Updated on: May 27,2024

Study: More aggressive treatments needed to improve 5-year survival rate for glioblastoma

by Joe Dangor,Mayo ClinicCredit: Mayo ClinicDespite improvements in median and short-term survival rates for patients with glioblastoma, the most common brain tumor in adults, the percentage of

Updated on:May 27,2024

Immune system plays vital role in longer multiple myeloma remission, new study shows

byUniversity of Miami Leonard M. Miller School of MedicineStudy design and treatment outcomes. a Immune profiling was performed on blood and bone marrow collected from 23 patients with multiple

Updated on: January 12,2024

Immune system plays vital role in longer multiple myeloma remission, new study shows

byUniversity of Miami Leonard M. Miller School of MedicineStudy design and treatment outcomes. a Immune profiling was performed on blood and bone marrow collected from 23 patients with multiple

Updated on:January 12,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on: January 07,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on:January 07,2024

Tackling resistance to HIF2 drugs with an RNA-based therapy

byUT Southwestern Medical CenterDownregulation of HIF2α by ARO-HIF2 in patient tumor biopsies. Credit: Dr. Payal KapurExpected to be diagnosed in 2% of men and 1% of women in the U.S., kidney ca

Updated on: December 28,2023

Tackling resistance to HIF2 drugs with an RNA-based therapy

byUT Southwestern Medical CenterDownregulation of HIF2α by ARO-HIF2 in patient tumor biopsies. Credit: Dr. Payal KapurExpected to be diagnosed in 2% of men and 1% of women in the U.S., kidney ca

Updated on:December 28,2023

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall

Updated on: July 05,2024

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall

Updated on:July 05,2024

Boys should be given HPV jab, says vaccine committee

by Cancer Research UKHuman papillomavirus (HPV) vaccine. Credit:Wikimedia Commons/CC BY-SA 2.0It's nearly a decade since the human papillomavirus (HPV) vaccine was first introduced in t

Updated on: May 11,2024

Boys should be given HPV jab, says vaccine committee

by Cancer Research UKHuman papillomavirus (HPV) vaccine. Credit:Wikimedia Commons/CC BY-SA 2.0It's nearly a decade since the human papillomavirus (HPV) vaccine was first introduced in t

Updated on:May 11,2024

Many breast cancer survivors do not receive genetic testing, despite being eligible

by Nicole Fawcett,University of MichiganCredit: Unsplash/CC0 Public DomainAs cancer treatment and survivorship care relies more on understanding the genetic make-up of an individual's tumor,

Updated on: July 17,2024

Many breast cancer survivors do not receive genetic testing, despite being eligible

by Nicole Fawcett,University of MichiganCredit: Unsplash/CC0 Public DomainAs cancer treatment and survivorship care relies more on understanding the genetic make-up of an individual's tumor,

Updated on:July 17,2024

Innovations in cancer treatment through targeted bacterial vaccines

byScience China PressThe schematic illustrates how the nanovaccine induces robust anti-F. nucleatum immune responses that significantly improve the efficiency of chemotherapy and reduce cancer m

Updated on: September 10,2024

Innovations in cancer treatment through targeted bacterial vaccines

byScience China PressThe schematic illustrates how the nanovaccine induces robust anti-F. nucleatum immune responses that significantly improve the efficiency of chemotherapy and reduce cancer m

Updated on:September 10,2024

Findings suggest common salt activates anti-tumor cells

by Friederike Gawlik, Leibniz Institute for Natural Product Research and Infection BiologyImmune cells (purple and blue) attack tumor cells (red). Highly active CD8⁺ T cells treated with sodium chlori

Updated on: September 10,2024

Findings suggest common salt activates anti-tumor cells

by Friederike Gawlik, Leibniz Institute for Natural Product Research and Infection BiologyImmune cells (purple and blue) attack tumor cells (red). Highly active CD8⁺ T cells treated with sodium chlori

Updated on:September 10,2024

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis

Updated on: January 02,2024

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis

Updated on:January 02,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on: January 26,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on:January 26,2024