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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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New lease on life for two lung cancer patients after pioneering double-lung transplant

New lease on life for two lung cancer patients after pioneering double-lung transplant

by Cara MurezRetired nurse Tannaz Ameli was diagnosed with stage 4 lung cancer last winter. When chemotherapy failed, her doctors recommended hospice care.But Ameli, of Minneapolis, had other ideas. S

New lease on life for two lung cancer patients after pioneering double-lung transplant

by Cara MurezRetired nurse Tannaz Ameli was diagnosed with stage 4 lung cancer last winter. When chemotherapy failed, her doctors recommended hospice care.But Ameli, of Minneapolis, had other ideas. S
Researchers compare tumor characteristics, survival outcome of different bile duct cancers

Researchers compare tumor characteristics, survival outcome of different bile duct cancers

byBoston University School of MedicineCredit: CC0 Public DomainCholangiocarcinoma (CCA) or bile duct cancer, is a rare, aggressive liver cancer with a poor prognosis, which occurs mostly in peop

Researchers compare tumor characteristics, survival outcome of different bile duct cancers

byBoston University School of MedicineCredit: CC0 Public DomainCholangiocarcinoma (CCA) or bile duct cancer, is a rare, aggressive liver cancer with a poor prognosis, which occurs mostly in peop
Unvaccinated cancer patients with COVID seven times more likely to die than comparable patients without COVID

Unvaccinated cancer patients with COVID seven times more likely to die than comparable patients without COVID

byRegenstrief InstituteKaplan-Meier survival estimates of overall cancer population by age group (years), Indiana, 2019-2020. Credit:JMIR Cancer(2022). DOI: 10.2196/35310Unvaccinated

Unvaccinated cancer patients with COVID seven times more likely to die than comparable patients without COVID

byRegenstrief InstituteKaplan-Meier survival estimates of overall cancer population by age group (years), Indiana, 2019-2020. Credit:JMIR Cancer(2022). DOI: 10.2196/35310Unvaccinated
Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi
How conquering a rare leukemia in children revolutionized cancer care for millions

How conquering a rare leukemia in children revolutionized cancer care for millions

by Marie McculloughFifty years ago, children with an aggressive form of leukemia went from diagnosis to death in a few months, as the disease rampaged through their lymph nodes, spleens, livers, and n

How conquering a rare leukemia in children revolutionized cancer care for millions

by Marie McculloughFifty years ago, children with an aggressive form of leukemia went from diagnosis to death in a few months, as the disease rampaged through their lymph nodes, spleens, livers, and n
Solid organ transplant patients may be at higher risk for skin cancer and require coordinated care

Solid organ transplant patients may be at higher risk for skin cancer and require coordinated care

by Jay Furst,Mayo ClinicCredit: AI-generated imageMore than half of all patients who receive solid organ transplants will have an incidence of skin cancer at some point—most often a nonmelanoma

Solid organ transplant patients may be at higher risk for skin cancer and require coordinated care

by Jay Furst,Mayo ClinicCredit: AI-generated imageMore than half of all patients who receive solid organ transplants will have an incidence of skin cancer at some point—most often a nonmelanoma
New study helps explain the anti-cancer properties of mannose sugar

New study helps explain the anti-cancer properties of mannose sugar

bySanford Burnham Prebys Medical Discovery InstituteProposed model for the mechanism underlying anticancer activity of mannose in mannose phosphate isomerase knockout (MPI-KO) human cancer cells

New study helps explain the anti-cancer properties of mannose sugar

bySanford Burnham Prebys Medical Discovery InstituteProposed model for the mechanism underlying anticancer activity of mannose in mannose phosphate isomerase knockout (MPI-KO) human cancer cells
Keeping aggressive cancer cells in check by blocking a protein responsible for repairs

Keeping aggressive cancer cells in check by blocking a protein responsible for repairs

by Catarina Pietschmann,Max Delbrück Center for Molecular MedicineThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained

Keeping aggressive cancer cells in check by blocking a protein responsible for repairs

by Catarina Pietschmann,Max Delbrück Center for Molecular MedicineThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained
As patients live longer, new criteria needed for prostate cancer trials

As patients live longer, new criteria needed for prostate cancer trials

JANUARY 26, 2024by Olivia Dimmer,Northwestern UniversityKaplan-Meier curves for (A) OS and rPFS and (B) OS and cPFS. cPFS=clinical progression-free survival; OS=overall survival; rPFS=radiograph

As patients live longer, new criteria needed for prostate cancer trials

JANUARY 26, 2024by Olivia Dimmer,Northwestern UniversityKaplan-Meier curves for (A) OS and rPFS and (B) OS and cPFS. cPFS=clinical progression-free survival; OS=overall survival; rPFS=radiograph
Right-sided colon cancer patients have poorer survival than those with left-sided disease

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv
New chemical weapon to combat cancer

New chemical weapon to combat cancer

by University of GenevaMultipolar melanoma cells stained for centrosomes (gamma-tubulin in red, centrin in green) and DNA (DAPI in blue). Scale bar represents 5 µm. Credit: UNIGEUNIGE researchers

New chemical weapon to combat cancer

by University of GenevaMultipolar melanoma cells stained for centrosomes (gamma-tubulin in red, centrin in green) and DNA (DAPI in blue). Scale bar represents 5 µm. Credit: UNIGEUNIGE researchers
Chemo drug may cause significant hearing loss in longtime cancer survivors

Chemo drug may cause significant hearing loss in longtime cancer survivors

byUniversity of South FloridaCredit: Unsplash/CC0 Public DomainAn interdisciplinary study led by researchers at the University of South Florida and Indiana University has uncovered significant f

Chemo drug may cause significant hearing loss in longtime cancer survivors

byUniversity of South FloridaCredit: Unsplash/CC0 Public DomainAn interdisciplinary study led by researchers at the University of South Florida and Indiana University has uncovered significant f