A new strategy to enhance gene therapy for sickle cell disease

byMary Ann Liebert, IncCyclosporin H Improves the Transduction of CD34+ Cells with an Anti-Sickling Globin Vector, a Possible Therapeutic Approach for Sickle Cell Disease. Credit: Mary Ann Liebe

Updated on: November 22,2024

A new strategy to enhance gene therapy for sickle cell disease

byMary Ann Liebert, IncCyclosporin H Improves the Transduction of CD34+ Cells with an Anti-Sickling Globin Vector, a Possible Therapeutic Approach for Sickle Cell Disease. Credit: Mary Ann Liebe

Updated on:November 22,2024

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on: February 20,2024

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on:February 20,2024

Adding metastasis-directed radiation therapy boosts progression-free survival in metastatic pancreatic cancer

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers from The University of Texas MD Anderson Cancer Center have demonstrated that adding metastasis-di

Updated on: August 28,2024

Adding metastasis-directed radiation therapy boosts progression-free survival in metastatic pancreatic cancer

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers from The University of Texas MD Anderson Cancer Center have demonstrated that adding metastasis-di

Updated on:August 28,2024

Single-cell analysis reveals how melanoma cells resist immunotherapy

by Karen Zusi,Broad Institute of MIT and HarvardCredit: Broad Institute of MIT and HarvardUnleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable

Updated on: March 12,2024

Single-cell analysis reveals how melanoma cells resist immunotherapy

by Karen Zusi,Broad Institute of MIT and HarvardCredit: Broad Institute of MIT and HarvardUnleashing the immune system to fight tumors—an approach enabled by immunotherapy—has led to remarkable

Updated on:March 12,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Mathematical modeling leads to a better understanding of prostate cancer

by Eva Schissler,University of CologneCredit:Cell Systems(2024). DOI: 10.1016/j.cels.2024.10.005A team led by Dr. Yuri Tolkach at the University of Cologne's Faculty of Medicine

Updated on: December 01,2024

Mathematical modeling leads to a better understanding of prostate cancer

by Eva Schissler,University of CologneCredit:Cell Systems(2024). DOI: 10.1016/j.cels.2024.10.005A team led by Dr. Yuri Tolkach at the University of Cologne's Faculty of Medicine

Updated on:December 01,2024

Prenatal exposure to anti-nausea drug in '60s, '70s tied to increased risk of colorectal cancer

byUniversity of Texas Health Science Center at HoustonCredit: Pixabay/CC0 Public DomainPrenatal exposure to an anti-nausea drug commonly used in the 1960s and 1970s has been shown to increase ri

Updated on: December 28,2023

Prenatal exposure to anti-nausea drug in '60s, '70s tied to increased risk of colorectal cancer

byUniversity of Texas Health Science Center at HoustonCredit: Pixabay/CC0 Public DomainPrenatal exposure to an anti-nausea drug commonly used in the 1960s and 1970s has been shown to increase ri

Updated on:December 28,2023

Keeping aggressive cancer cells in check by blocking a protein responsible for repairs

by Catarina Pietschmann,Max Delbrück Center for Molecular MedicineThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained

Updated on: January 07,2024

Keeping aggressive cancer cells in check by blocking a protein responsible for repairs

by Catarina Pietschmann,Max Delbrück Center for Molecular MedicineThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained

Updated on:January 07,2024

Researchers propose a navigation system to tackle medication supply bottlenecks

by Christoph Elhardt,ETH ZurichWholesalers can ease supply bottlenecks by rerouting remainder stocks of medications in short supply. Credit: ETH ZurichSupply bottlenecks for medications present

Updated on: May 06,2024

Researchers propose a navigation system to tackle medication supply bottlenecks

by Christoph Elhardt,ETH ZurichWholesalers can ease supply bottlenecks by rerouting remainder stocks of medications in short supply. Credit: ETH ZurichSupply bottlenecks for medications present

Updated on:May 06,2024

Largest study of its kind reveals adjuvant chemotherapy improves overall survival for pancreatic cancer patients

byCU Anschutz Medical CampusCredit: CC0 Public DomainToday, the University of Colorado Cancer Center released new research that showcases chemotherapy treatment before and after surgery for panc

Updated on: January 07,2024

Largest study of its kind reveals adjuvant chemotherapy improves overall survival for pancreatic cancer patients

byCU Anschutz Medical CampusCredit: CC0 Public DomainToday, the University of Colorado Cancer Center released new research that showcases chemotherapy treatment before and after surgery for panc

Updated on:January 07,2024

Research perspective: Cancer prevention with rapamycin

by Impact Journals LLCRapamycin prevents cancer by slowing tumor progression (hypothetical schema). (A) Rapamycin slows tumor progression and delays cancer and death from cancer. (B) Rapamycin slows t

Updated on: January 30,2024

Research perspective: Cancer prevention with rapamycin

by Impact Journals LLCRapamycin prevents cancer by slowing tumor progression (hypothetical schema). (A) Rapamycin slows tumor progression and delays cancer and death from cancer. (B) Rapamycin slows t

Updated on:January 30,2024

Researchers discover marker that may show when a type of skin cancer is preparing to metastasize

by Center for Genomic RegulationFrom left to right: Noemí Haro, Óscar Pozo, Inma Hernández-Muñoz, Evelyn Andrades, Paloma Torres & Ramon Pujol. Credit: Hospital de Mar/IMIMCells that form cutaneou

Updated on: February 20,2024

Researchers discover marker that may show when a type of skin cancer is preparing to metastasize

by Center for Genomic RegulationFrom left to right: Noemí Haro, Óscar Pozo, Inma Hernández-Muñoz, Evelyn Andrades, Paloma Torres & Ramon Pujol. Credit: Hospital de Mar/IMIMCells that form cutaneou

Updated on:February 20,2024