CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Updated on: April 09,2024

CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Updated on:April 09,2024

How Leukemia Is Treated

How Leukemia Is TreatedByKaren RaymaakersUpdated on January 22, 2023Medically reviewed byDouglas A. Nelson, MDThe treatment forleukemiadepends on many factors inclu

Updated on: February 04,2024

How Leukemia Is Treated

How Leukemia Is TreatedByKaren RaymaakersUpdated on January 22, 2023Medically reviewed byDouglas A. Nelson, MDThe treatment forleukemiadepends on many factors inclu

Updated on:February 04,2024

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on: January 12,2024

New computer platform helps match patients with cancer to trials of targeted therapy

byDana-Farber Cancer InstituteMatchMiner overview of data flow and modes of use. a) Data inputs from patients and trials are utilized by the MatchEngine to match patients to trials. b) Shown are

Updated on:January 12,2024

Research shows PSMA PET/CT imaging changes management for close to 50% of prostate cancer patients

by Society of Nuclear Medicine and Molecular ImagingGraphical Abstract: Patients with detectable PSA (0.2-2.0 ng/mL) post-prostatectomy considered for salvage radiotherapy undergoing18F-DCFPyL P

Updated on: January 22,2024

Research shows PSMA PET/CT imaging changes management for close to 50% of prostate cancer patients

by Society of Nuclear Medicine and Molecular ImagingGraphical Abstract: Patients with detectable PSA (0.2-2.0 ng/mL) post-prostatectomy considered for salvage radiotherapy undergoing18F-DCFPyL P

Updated on:January 22,2024

Keeping aggressive cancer cells in check by blocking a protein responsible for repairs

by Catarina Pietschmann,Max Delbrück Center for Molecular MedicineThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained

Updated on: January 07,2024

Keeping aggressive cancer cells in check by blocking a protein responsible for repairs

by Catarina Pietschmann,Max Delbrück Center for Molecular MedicineThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained

Updated on:January 07,2024

Pancreatic cancer vaccine plus immunotherapy and antibody spark immune system response in pancreatic cancers

by Johns Hopkins University School of MedicineJ1568 study treatment schema.Eligible patients with clinically resectable PDA received the first priming study treatment Cy-GVAX-based therapy (alone

Updated on: January 30,2024

Pancreatic cancer vaccine plus immunotherapy and antibody spark immune system response in pancreatic cancers

by Johns Hopkins University School of MedicineJ1568 study treatment schema.Eligible patients with clinically resectable PDA received the first priming study treatment Cy-GVAX-based therapy (alone

Updated on:January 30,2024

Study reveals lower survival rates for women than men with germ cell tumors

by Uppsala UniversityThe cell of origin, the normal development of sperm and oocytes, and the corresponding tumor development of malignant ovarian and testicular germ cell tumors. Credit:Jo

Updated on: March 20,2024

Study reveals lower survival rates for women than men with germ cell tumors

by Uppsala UniversityThe cell of origin, the normal development of sperm and oocytes, and the corresponding tumor development of malignant ovarian and testicular germ cell tumors. Credit:Jo

Updated on:March 20,2024

Novel AI method identifies locations, interactions among genes in and around tumors

byJohns Hopkins University School of MedicineImage of a breast cancer tissue sample overlaid with visual representations of spatially interacting patterns of tumor and immune activity obtained t

Updated on: January 12,2024

Novel AI method identifies locations, interactions among genes in and around tumors

byJohns Hopkins University School of MedicineImage of a breast cancer tissue sample overlaid with visual representations of spatially interacting patterns of tumor and immune activity obtained t

Updated on:January 12,2024

Researchers unlock mysteries of complex microRNA oncogenes

by McGill UniversityMicroRNA and mRNA visualization in differentiating C1C12 cells. Credit: Ryan Jeffs/WikipediaMicroRNAs are tiny molecules of nucleic acid that control gene expression, acting l

Updated on: June 11,2024

Researchers unlock mysteries of complex microRNA oncogenes

by McGill UniversityMicroRNA and mRNA visualization in differentiating C1C12 cells. Credit: Ryan Jeffs/WikipediaMicroRNAs are tiny molecules of nucleic acid that control gene expression, acting l

Updated on:June 11,2024

Researchers publish action plan to address appendiceal cancer enigmas

Updated on: April 29,2025

Researchers publish action plan to address appendiceal cancer enigmas

Updated on:April 29,2025

Moderate exercise helps colorectal cancer patients live longer by reducing inflammation and improving gut bacteria

by Heather Simonsen,University of UtahCredit: Pixabay/CC0 Public DomainRegular physical activity can extend colorectal cancer patients' lives. In a first-ever study, scientists looked at the

Updated on: January 04,2024

Moderate exercise helps colorectal cancer patients live longer by reducing inflammation and improving gut bacteria

by Heather Simonsen,University of UtahCredit: Pixabay/CC0 Public DomainRegular physical activity can extend colorectal cancer patients' lives. In a first-ever study, scientists looked at the

Updated on:January 04,2024

PSA levels after treatment may not be reliable predictor of survival for patients with prostate cancer

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainA UCLA-led study has found treatments that reduce the risk of being diagnosed with a cancer recurrence based on rising pr

Updated on: February 18,2024

PSA levels after treatment may not be reliable predictor of survival for patients with prostate cancer

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainA UCLA-led study has found treatments that reduce the risk of being diagnosed with a cancer recurrence based on rising pr

Updated on:February 18,2024