Breast cancer spread uncovered by new molecular microscopy

byWellcome Trust Sanger InstituteConverting BaSISS spatial signals into maps of clones.a, Bar plots of cancer cell fractions (CCFs) derived from bulk WGS of the P1 samples.b, P

Updated on: January 11,2024

Breast cancer spread uncovered by new molecular microscopy

byWellcome Trust Sanger InstituteConverting BaSISS spatial signals into maps of clones.a, Bar plots of cancer cell fractions (CCFs) derived from bulk WGS of the P1 samples.b, P

Updated on:January 11,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on: March 14,2024

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on:March 14,2024

Wide variation in bowel cancer rates after colonoscopies in England

by British Medical JournalBowel cancer survivor John Barnes. Credit: University of LeedsSubstantial variation exists between colonoscopy providers in rates of bowel cancer up to three years after

Updated on: May 11,2024

Wide variation in bowel cancer rates after colonoscopies in England

by British Medical JournalBowel cancer survivor John Barnes. Credit: University of LeedsSubstantial variation exists between colonoscopy providers in rates of bowel cancer up to three years after

Updated on:May 11,2024

Tackling resistance to HIF2 drugs with an RNA-based therapy

byUT Southwestern Medical CenterDownregulation of HIF2α by ARO-HIF2 in patient tumor biopsies. Credit: Dr. Payal KapurExpected to be diagnosed in 2% of men and 1% of women in the U.S., kidney ca

Updated on: December 28,2023

Tackling resistance to HIF2 drugs with an RNA-based therapy

byUT Southwestern Medical CenterDownregulation of HIF2α by ARO-HIF2 in patient tumor biopsies. Credit: Dr. Payal KapurExpected to be diagnosed in 2% of men and 1% of women in the U.S., kidney ca

Updated on:December 28,2023

Innovations in cancer treatment through targeted bacterial vaccines

byScience China PressThe schematic illustrates how the nanovaccine induces robust anti-F. nucleatum immune responses that significantly improve the efficiency of chemotherapy and reduce cancer m

Updated on: September 10,2024

Innovations in cancer treatment through targeted bacterial vaccines

byScience China PressThe schematic illustrates how the nanovaccine induces robust anti-F. nucleatum immune responses that significantly improve the efficiency of chemotherapy and reduce cancer m

Updated on:September 10,2024

Immune system plays vital role in longer multiple myeloma remission, new study shows

byUniversity of Miami Leonard M. Miller School of MedicineStudy design and treatment outcomes. a Immune profiling was performed on blood and bone marrow collected from 23 patients with multiple

Updated on: January 12,2024

Immune system plays vital role in longer multiple myeloma remission, new study shows

byUniversity of Miami Leonard M. Miller School of MedicineStudy design and treatment outcomes. a Immune profiling was performed on blood and bone marrow collected from 23 patients with multiple

Updated on:January 12,2024

Trial shows improvements in several clinical outcomes for men with intermediate-risk prostate cancer

by NRG OncologyCredit: Unsplash/CC0 Public DomainResults from the phase 3 NRG Oncology RTOG 0815 clinical study comparing dose-escalated radiotherapy (RT) alone to dose-escalated RT with short-term an

Updated on: January 04,2024

Trial shows improvements in several clinical outcomes for men with intermediate-risk prostate cancer

by NRG OncologyCredit: Unsplash/CC0 Public DomainResults from the phase 3 NRG Oncology RTOG 0815 clinical study comparing dose-escalated radiotherapy (RT) alone to dose-escalated RT with short-term an

Updated on:January 04,2024

Many breast cancer survivors do not receive genetic testing, despite being eligible

by Nicole Fawcett,University of MichiganCredit: Unsplash/CC0 Public DomainAs cancer treatment and survivorship care relies more on understanding the genetic make-up of an individual's tumor,

Updated on: July 17,2024

Many breast cancer survivors do not receive genetic testing, despite being eligible

by Nicole Fawcett,University of MichiganCredit: Unsplash/CC0 Public DomainAs cancer treatment and survivorship care relies more on understanding the genetic make-up of an individual's tumor,

Updated on:July 17,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on: January 07,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on:January 07,2024

Research perspective: Cancer prevention with rapamycin

by Impact Journals LLCRapamycin prevents cancer by slowing tumor progression (hypothetical schema). (A) Rapamycin slows tumor progression and delays cancer and death from cancer. (B) Rapamycin slows t

Updated on: January 30,2024

Research perspective: Cancer prevention with rapamycin

by Impact Journals LLCRapamycin prevents cancer by slowing tumor progression (hypothetical schema). (A) Rapamycin slows tumor progression and delays cancer and death from cancer. (B) Rapamycin slows t

Updated on:January 30,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on: January 26,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on:January 26,2024