Dual checkpoint inhibitor blockade shows promise as first-line and salvage therapy for Merkel cell carcinoma patients

byH. Lee Moffitt Cancer Center & Research InstituteMicrograph of a lung primary small cell carcinoma, a type of carcinoma. Credit: WikipediaMerkel cell carcinoma is a rare but aggressive for

Updated on: January 04,2024

Dual checkpoint inhibitor blockade shows promise as first-line and salvage therapy for Merkel cell carcinoma patients

byH. Lee Moffitt Cancer Center & Research InstituteMicrograph of a lung primary small cell carcinoma, a type of carcinoma. Credit: WikipediaMerkel cell carcinoma is a rare but aggressive for

Updated on:January 04,2024

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis

Updated on: January 02,2024

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis

Updated on:January 02,2024

Study reveals mechanism linking heart disease to cancer development

byTel-Aviv UniversityCredit: CC0 Public DomainResearchers at Tel Aviv University (TAU) and the Leviev Cardiothoracic and Vascular Center at the Sheba Medical Center have found a mechanism respon

Updated on: April 28,2024

Study reveals mechanism linking heart disease to cancer development

byTel-Aviv UniversityCredit: CC0 Public DomainResearchers at Tel Aviv University (TAU) and the Leviev Cardiothoracic and Vascular Center at the Sheba Medical Center have found a mechanism respon

Updated on:April 28,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

How much sun can (and should) I get?

by Katie Lee and Rachel Neale,The ConversationCredit: Unsplash/CC0 Public DomainAs we slide of out summer, you might be wondering how careful you need to be about sun exposure. Excessive exposur

Updated on: March 30,2024

How much sun can (and should) I get?

by Katie Lee and Rachel Neale,The ConversationCredit: Unsplash/CC0 Public DomainAs we slide of out summer, you might be wondering how careful you need to be about sun exposure. Excessive exposur

Updated on:March 30,2024

Study shows elevated cancer risk for women with endometriosis

byHuntsman Cancer InstituteCredit: CC0 Public DomainA landmark study from researchers at Huntsman Cancer Institute at the University of Utah (the U), the Spencer Fox Eccles School of Medicine at

Updated on: August 03,2024

Study shows elevated cancer risk for women with endometriosis

byHuntsman Cancer InstituteCredit: CC0 Public DomainA landmark study from researchers at Huntsman Cancer Institute at the University of Utah (the U), the Spencer Fox Eccles School of Medicine at

Updated on:August 03,2024

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on: March 14,2024

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on:March 14,2024

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall

Updated on: July 05,2024

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall

Updated on:July 05,2024

Trial results show PARP inhibitor benefit in 'BRCA-like' breast cancer

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainResults from the SWOG S1416 clinical trial show that adding veliparib to chemotherapy can significantly extend progression-free surviva

Updated on: January 04,2024

Trial results show PARP inhibitor benefit in 'BRCA-like' breast cancer

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainResults from the SWOG S1416 clinical trial show that adding veliparib to chemotherapy can significantly extend progression-free surviva

Updated on:January 04,2024

Time of day matters when it comes to cancer diagnosis and treatment, says metastasis study

byCell PressCredit: Unsplash/CC0 Public DomainYour circadian rhythm doesn't just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment. In a review p

Updated on: January 23,2024

Time of day matters when it comes to cancer diagnosis and treatment, says metastasis study

byCell PressCredit: Unsplash/CC0 Public DomainYour circadian rhythm doesn't just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment. In a review p

Updated on:January 23,2024

Study reveals how diet and probiotics boost melanoma immunotherapy response

by University of PittsburghMarlies Meisel, Ph.D., assistant professor in the Department of Immunology at the University of Pittsburgh School of Medicine and member of the Cancer Immunology and Im

Updated on: February 23,2024

Study reveals how diet and probiotics boost melanoma immunotherapy response

by University of PittsburghMarlies Meisel, Ph.D., assistant professor in the Department of Immunology at the University of Pittsburgh School of Medicine and member of the Cancer Immunology and Im

Updated on:February 23,2024

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Updated on: February 24,2024

Inhibiting the biological crosstalk of autophagy and mitochondrial function underlying pancreatic ductal adenocarcinoma

by Thamarasee Jeewandara , Medical XpressAutophagy inhibition leads to a drop in the LIP in PDAC. (A) Autophagy was inhibited genetically or pharmacologically in PDAC cells, and the relative LIP was d

Updated on:February 24,2024