Study: Key mechanisms of action differences in immune checkpoint inhibitor combination therapies for advanced melanoma

byH. Lee Moffitt Cancer Center & Research InstituteProposed mechanism of the two ICI combinations. Graphic created with Biorender (biorender.com). ICI, immune checkpoint inhibitor. Credit:&n

Updated on: January 25,2024

Study: Key mechanisms of action differences in immune checkpoint inhibitor combination therapies for advanced melanoma

byH. Lee Moffitt Cancer Center & Research InstituteProposed mechanism of the two ICI combinations. Graphic created with Biorender (biorender.com). ICI, immune checkpoint inhibitor. Credit:&n

Updated on:January 25,2024

Dual checkpoint inhibitor blockade shows promise as first-line and salvage therapy for Merkel cell carcinoma patients

byH. Lee Moffitt Cancer Center & Research InstituteMicrograph of a lung primary small cell carcinoma, a type of carcinoma. Credit: WikipediaMerkel cell carcinoma is a rare but aggressive for

Updated on: January 04,2024

Dual checkpoint inhibitor blockade shows promise as first-line and salvage therapy for Merkel cell carcinoma patients

byH. Lee Moffitt Cancer Center & Research InstituteMicrograph of a lung primary small cell carcinoma, a type of carcinoma. Credit: WikipediaMerkel cell carcinoma is a rare but aggressive for

Updated on:January 04,2024

Breast cancer spread uncovered by new molecular microscopy

byWellcome Trust Sanger InstituteConverting BaSISS spatial signals into maps of clones.a, Bar plots of cancer cell fractions (CCFs) derived from bulk WGS of the P1 samples.b, P

Updated on: January 11,2024

Breast cancer spread uncovered by new molecular microscopy

byWellcome Trust Sanger InstituteConverting BaSISS spatial signals into maps of clones.a, Bar plots of cancer cell fractions (CCFs) derived from bulk WGS of the P1 samples.b, P

Updated on:January 11,2024

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on: March 14,2024

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on:March 14,2024

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis

Updated on: January 02,2024

How oxygen deprivation causes cancer cells to spread

byLeiden UniversityCredit: Pixabay/CC0 Public DomainIn breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis

Updated on:January 02,2024

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv

Updated on: May 07,2024

Right-sided colon cancer patients have poorer survival than those with left-sided disease

by American College of SurgeonsKiller T cells surround a cancer cell. Credit: NIHORLANDO (July 23, 2018): Patients with colorectal cancer tumors on the right side may have poorer five-year surviv

Updated on:May 07,2024

Aggressive breast cancers store large amounts of energy, which enables it to spread: study

by University of MichiganSofia Merajver, M.D., Ph.D. Credit: University of Michigan Rogel Cancer CenterCancer cells—especially the more aggressive ones—seem to have an ability to change. It's

Updated on: June 28,2024

Aggressive breast cancers store large amounts of energy, which enables it to spread: study

by University of MichiganSofia Merajver, M.D., Ph.D. Credit: University of Michigan Rogel Cancer CenterCancer cells—especially the more aggressive ones—seem to have an ability to change. It's

Updated on:June 28,2024

Cancer metastasis: Tumor plasticity counts

by Université libre de BruxellesCredit: CC0 Public DomainCancer metastasis, which is the propagation of tumor cells into distant organs, is the leading cause of cancer patient mortality. To under

Updated on: March 12,2024

Cancer metastasis: Tumor plasticity counts

by Université libre de BruxellesCredit: CC0 Public DomainCancer metastasis, which is the propagation of tumor cells into distant organs, is the leading cause of cancer patient mortality. To under

Updated on:March 12,2024

Aggressive cancer cells grow by protecting their identity, shows study

byRuhr-Universitaet-BochumGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112533For most types of cancer, the primary tumor is not the cause of death, but m

Updated on: January 22,2024

Aggressive cancer cells grow by protecting their identity, shows study

byRuhr-Universitaet-BochumGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112533For most types of cancer, the primary tumor is not the cause of death, but m

Updated on:January 22,2024

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall

Updated on: July 05,2024

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall

Updated on:July 05,2024

Interpreting and Commenting on the Role of Oct4 in M2 Macrophage Polarization and Tumor Progression in Lung Cancer

Updated on: October 01,2024

Interpreting and Commenting on the Role of Oct4 in M2 Macrophage Polarization and Tumor Progression in Lung Cancer

Updated on:October 01,2024

Trial results show PARP inhibitor benefit in 'BRCA-like' breast cancer

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainResults from the SWOG S1416 clinical trial show that adding veliparib to chemotherapy can significantly extend progression-free surviva

Updated on: January 04,2024

Trial results show PARP inhibitor benefit in 'BRCA-like' breast cancer

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainResults from the SWOG S1416 clinical trial show that adding veliparib to chemotherapy can significantly extend progression-free surviva

Updated on:January 04,2024