Gene signature to tailor chemotherapy shows promise for improving breast cancer survival

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainUsing a gene signature technique to tailor chemotherapy for patients with early triple negative breast cancer shows promise as a way to

Updated on: November 08,2024

Gene signature to tailor chemotherapy shows promise for improving breast cancer survival

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainUsing a gene signature technique to tailor chemotherapy for patients with early triple negative breast cancer shows promise as a way to

Updated on:November 08,2024

New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children

byElsevierLeft: Gross images of livers from mice transfected with β-catenin and YAP1(β-Y), β-catenin and YAP1 plus dominant negative HSF1 (dnHSF1-β-Y) and normal (control). Right: Liver to body

Updated on: January 13,2024

New research identifies a potential treatment target for hepatoblastoma, the most common liver cancer in children

byElsevierLeft: Gross images of livers from mice transfected with β-catenin and YAP1(β-Y), β-catenin and YAP1 plus dominant negative HSF1 (dnHSF1-β-Y) and normal (control). Right: Liver to body

Updated on:January 13,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on: January 26,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on:January 26,2024

Research illuminates a therapeutic strategy to induce cancer cell death

by Rachel Sauer,CU Anschutz Medical CampusCredit: CC0 Public DomainCancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumor suppressors a

Updated on: January 22,2024

Research illuminates a therapeutic strategy to induce cancer cell death

by Rachel Sauer,CU Anschutz Medical CampusCredit: CC0 Public DomainCancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumor suppressors a

Updated on:January 22,2024

Adding metastasis-directed radiation therapy boosts progression-free survival in metastatic pancreatic cancer

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers from The University of Texas MD Anderson Cancer Center have demonstrated that adding metastasis-di

Updated on: August 28,2024

Adding metastasis-directed radiation therapy boosts progression-free survival in metastatic pancreatic cancer

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainResearchers from The University of Texas MD Anderson Cancer Center have demonstrated that adding metastasis-di

Updated on:August 28,2024

Aggressive breast cancers store large amounts of energy, which enables it to spread: study

by University of MichiganSofia Merajver, M.D., Ph.D. Credit: University of Michigan Rogel Cancer CenterCancer cells—especially the more aggressive ones—seem to have an ability to change. It's

Updated on: June 28,2024

Aggressive breast cancers store large amounts of energy, which enables it to spread: study

by University of MichiganSofia Merajver, M.D., Ph.D. Credit: University of Michigan Rogel Cancer CenterCancer cells—especially the more aggressive ones—seem to have an ability to change. It's

Updated on:June 28,2024

Activation of a distinct genetic pathway can slow the progress of metastatic breast cancer

by Olivia Newton-John Cancer Research InstituteImmunofluorescent staining reveals activation of the BMP-Smad signaling pathway in metastatic breast cancer cells in response to BMP4 stimulation (left p

Updated on: December 20,2023

Activation of a distinct genetic pathway can slow the progress of metastatic breast cancer

by Olivia Newton-John Cancer Research InstituteImmunofluorescent staining reveals activation of the BMP-Smad signaling pathway in metastatic breast cancer cells in response to BMP4 stimulation (left p

Updated on:December 20,2023

Development of a novel bispecific antibody therapy to overcome myeloma heterogeneity

by Ehime UniversityMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Multiple myeloma is still an incurable hematological ma

Updated on: March 25,2024

Development of a novel bispecific antibody therapy to overcome myeloma heterogeneity

by Ehime UniversityMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Multiple myeloma is still an incurable hematological ma

Updated on:March 25,2024

Swallowable device to detect Barrett's esophagus receives FDA 510(k) clearance

by Case Western Reserve University"FDA clearance of the EsoCheck device means the device is now available to patients and physicians as a non-endoscopic method for sampling the esophagus. Th

Updated on: May 09,2024

Swallowable device to detect Barrett's esophagus receives FDA 510(k) clearance

by Case Western Reserve University"FDA clearance of the EsoCheck device means the device is now available to patients and physicians as a non-endoscopic method for sampling the esophagus. Th

Updated on:May 09,2024

Anti-diabetic drugs could lower risk of primary and secondary brain cancer

by University of BristolCredit: CC0 Public DomainDiabetic patients who take anti-diabetic drugs—known as glitazones—long term had a lower risk of primary and secondary brain cancer compared with

Updated on: April 07,2024

Anti-diabetic drugs could lower risk of primary and secondary brain cancer

by University of BristolCredit: CC0 Public DomainDiabetic patients who take anti-diabetic drugs—known as glitazones—long term had a lower risk of primary and secondary brain cancer compared with

Updated on:April 07,2024

Scientists develop potential stealth cancer therapy

by Yale Cancer Center/Smilow Cancer HospitalCredit:ACS Central Science(2024). DOI: 10.1021/acscentsci.4c00559Sneaking by cancer's defenses, by disguising tumor-fighting antibodies insi

Updated on: July 17,2024

Scientists develop potential stealth cancer therapy

by Yale Cancer Center/Smilow Cancer HospitalCredit:ACS Central Science(2024). DOI: 10.1021/acscentsci.4c00559Sneaking by cancer's defenses, by disguising tumor-fighting antibodies insi

Updated on:July 17,2024

Scientists find way to starve breast cancer cells

by Jennifer Michalowski,Cold Spring Harbor LaboratoryWhen fast-growing breast cancer cells run out of glutamine, they turn to an alternative supply line. PHGDH (above, in green) is a key enzyme

Updated on: September 07,2024

Scientists find way to starve breast cancer cells

by Jennifer Michalowski,Cold Spring Harbor LaboratoryWhen fast-growing breast cancer cells run out of glutamine, they turn to an alternative supply line. PHGDH (above, in green) is a key enzyme

Updated on:September 07,2024