Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on: December 18,2023

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on:December 18,2023

Study investigates the unresolved palliative care needs of elderly, homebound noncancer patients

by University of TsukubaCredit: Kampus Production from PexelsIn Japan, approximately 70% of deaths occur among noncancer patients who often experience more frequent and varied distressing symptom

Updated on: March 15,2024

Study investigates the unresolved palliative care needs of elderly, homebound noncancer patients

by University of TsukubaCredit: Kampus Production from PexelsIn Japan, approximately 70% of deaths occur among noncancer patients who often experience more frequent and varied distressing symptom

Updated on:March 15,2024

Hormone resistance in breast cancer linked to DNA 'rewiring'

byGarvan Institute of Medical ResearchCredit: CC0 Public DomainEpigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatm

Updated on: December 20,2023

Hormone resistance in breast cancer linked to DNA 'rewiring'

byGarvan Institute of Medical ResearchCredit: CC0 Public DomainEpigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatm

Updated on:December 20,2023

New insights into the drivers of glioma-related epilepsy

by Graciela Gutierrez,Baylor College of MedicineGraphical abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.01.013Glioma is one of the most aggressive malignant primary brain

Updated on: December 20,2023

New insights into the drivers of glioma-related epilepsy

by Graciela Gutierrez,Baylor College of MedicineGraphical abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.01.013Glioma is one of the most aggressive malignant primary brain

Updated on:December 20,2023

Targeting epiregulin in treatment-damaged tumor microenvironment restrains therapeutic resistance

by Liu Jia,Chinese Academy of SciencesGenotoxicity induces expression of EREG and other secreted factors of the SASP spectrum in human stromal cells.aTranscriptome-wide profiling of

Updated on: December 19,2023

Targeting epiregulin in treatment-damaged tumor microenvironment restrains therapeutic resistance

by Liu Jia,Chinese Academy of SciencesGenotoxicity induces expression of EREG and other secreted factors of the SASP spectrum in human stromal cells.aTranscriptome-wide profiling of

Updated on:December 19,2023

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Updated on: December 21,2023

Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer

byUniversity of BarcelonaGenetic models to mimic SMAD2/3 alterations in patient-derived ADC-TAFs and SCC-TAFs. a–c, Fold SMAD3 (a) and SMAD2 (b) mRNA and corresponding ratio (c) in primary lung

Updated on:December 21,2023

Symptom self-monitoring for childhood cancer survivors—what are oncologists' views?

byKing's College LondonCredit: Unsplash/CC0 Public DomainA new international survey, led by the Stanford University Department of Anesthesiology, Perioperative, and Pain Medicine, and the In

Updated on: December 21,2023

Symptom self-monitoring for childhood cancer survivors—what are oncologists' views?

byKing's College LondonCredit: Unsplash/CC0 Public DomainA new international survey, led by the Stanford University Department of Anesthesiology, Perioperative, and Pain Medicine, and the In

Updated on:December 21,2023

Is the next big step in cancer therapy personalized vaccines?

byUniversity of California - San DiegoEzra Cohen, MD, UC San Diego Health physician scientist, administered the first-of-its-kind personalized cancer vaccine to Tamara Strauss, while Aaron Mille

Updated on: December 18,2023

Is the next big step in cancer therapy personalized vaccines?

byUniversity of California - San DiegoEzra Cohen, MD, UC San Diego Health physician scientist, administered the first-of-its-kind personalized cancer vaccine to Tamara Strauss, while Aaron Mille

Updated on:December 18,2023

AI-assisted breast-cancer screening may reduce unnecessary testing

byWashington University School of MedicineOn average, radiologists find one case of cancer (bottom images) in every 200 mammograms they evaluate. The top images show no cancer. In a recent study

Updated on: April 27,2024

AI-assisted breast-cancer screening may reduce unnecessary testing

byWashington University School of MedicineOn average, radiologists find one case of cancer (bottom images) in every 200 mammograms they evaluate. The top images show no cancer. In a recent study

Updated on:April 27,2024

The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response

byJosep Carreras Leukaemia Research InstituteTAD dynamics along p53 activation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46666-1The simplest explanation of cancer

Updated on: April 28,2024

The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response

byJosep Carreras Leukaemia Research InstituteTAD dynamics along p53 activation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46666-1The simplest explanation of cancer

Updated on:April 28,2024

Druggable targets found for treating rare, deadly nerve cancer MPNST

byCincinnati Children's Hospital Medical CenterTumor cell–state trajectories from NF to MPNST inferred by Slingshot. Arrows, transformation direction. Credit: Cincinnati Children's and S

Updated on: December 22,2023

Druggable targets found for treating rare, deadly nerve cancer MPNST

byCincinnati Children's Hospital Medical CenterTumor cell–state trajectories from NF to MPNST inferred by Slingshot. Arrows, transformation direction. Credit: Cincinnati Children's and S

Updated on:December 22,2023

The Role of Senescent Macrophages in KRAS-Driven Lung Cancer:Insights from Novel p16-FDR Mouse Models and Therapeutic Implications

Updated on: July 27,2024

The Role of Senescent Macrophages in KRAS-Driven Lung Cancer:Insights from Novel p16-FDR Mouse Models and Therapeutic Implications

Updated on:July 27,2024