AFM24 Plus Atezolizumab Shows Acceptable Safety, Early Activity in EGFR+ Solid Tumors

January 14, 2023Ryan ScottA doublet comprised of the bispecific innate cell engager AFM24 and atezolizumab had a tolerable safety profile and elicited responses in patients with advanced EGFR-expressi

Updated on: October 15,2023 163

AFM24 Plus Atezolizumab Shows Acceptable Safety, Early Activity in EGFR+ Solid Tumors

January 14, 2023Ryan ScottA doublet comprised of the bispecific innate cell engager AFM24 and atezolizumab had a tolerable safety profile and elicited responses in patients with advanced EGFR-expressi

Updated on:October 15,2023 163

Scientists identify protein crucial to tumor cells' metabolism and immune evasion

by Katie Marquedant,Massachusetts General HospitalCredit: CC0 Public DomainTumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spr

Updated on: December 27,2023 8

Scientists identify protein crucial to tumor cells' metabolism and immune evasion

by Katie Marquedant,Massachusetts General HospitalCredit: CC0 Public DomainTumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spr

Updated on:December 27,2023 8

Cancer mortality continues steady decline, driven by progress against lung cancer

byAmerican Cancer SocietyTrends in Overall Cancer Mortality Rates by Sex, United States, 1930 to 2017. Rates are age adjusted to the 2000 US standard population Credit: American Cancer SocietyTh

Updated on: December 22,2023 19

Cancer mortality continues steady decline, driven by progress against lung cancer

byAmerican Cancer SocietyTrends in Overall Cancer Mortality Rates by Sex, United States, 1930 to 2017. Rates are age adjusted to the 2000 US standard population Credit: American Cancer SocietyTh

Updated on:December 22,2023 19

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on: December 20,2023 8

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on:December 20,2023 8

Mailed orders found to double liver cancer screening rates

byPerelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainLiver cancer screening among patients with cirrhosis almost doubled when they were mailed a signe

Updated on: December 26,2023 20

Mailed orders found to double liver cancer screening rates

byPerelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainLiver cancer screening among patients with cirrhosis almost doubled when they were mailed a signe

Updated on:December 26,2023 20

New algorithm detects even the smallest cancer metastases across the entire mouse body

byHelmholtz Association of German Research CentresDeepMACT makes use of artificial intelligence to find even the smallest metastases in the entire mouse body. The picture shows single disseminat

Updated on: December 23,2023 17

New algorithm detects even the smallest cancer metastases across the entire mouse body

byHelmholtz Association of German Research CentresDeepMACT makes use of artificial intelligence to find even the smallest metastases in the entire mouse body. The picture shows single disseminat

Updated on:December 23,2023 17

Scientists identify a gene signature to assess cancer risk in people

byThe Wistar InstituteWistar's Dr. Maureen Murphy and lab. Credit: The Wistar InstituteIn a paper published inPNAS, Maureen Murphy, Ph.D., Deputy Director of Wistar's Ellen and Ron

Updated on: December 27,2023 10

Scientists identify a gene signature to assess cancer risk in people

byThe Wistar InstituteWistar's Dr. Maureen Murphy and lab. Credit: The Wistar InstituteIn a paper published inPNAS, Maureen Murphy, Ph.D., Deputy Director of Wistar's Ellen and Ron

Updated on:December 27,2023 10

Druggable targets found for treating rare, deadly nerve cancer MPNST

byCincinnati Children's Hospital Medical CenterTumor cell–state trajectories from NF to MPNST inferred by Slingshot. Arrows, transformation direction. Credit: Cincinnati Children's and S

Updated on: December 22,2023 10

Druggable targets found for treating rare, deadly nerve cancer MPNST

byCincinnati Children's Hospital Medical CenterTumor cell–state trajectories from NF to MPNST inferred by Slingshot. Arrows, transformation direction. Credit: Cincinnati Children's and S

Updated on:December 22,2023 10

Hormone resistance in breast cancer linked to DNA 'rewiring'

byGarvan Institute of Medical ResearchCredit: CC0 Public DomainEpigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatm

Updated on: December 20,2023 16

Hormone resistance in breast cancer linked to DNA 'rewiring'

byGarvan Institute of Medical ResearchCredit: CC0 Public DomainEpigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatm

Updated on:December 20,2023 16

Is the next big step in cancer therapy personalized vaccines?

byUniversity of California - San DiegoEzra Cohen, MD, UC San Diego Health physician scientist, administered the first-of-its-kind personalized cancer vaccine to Tamara Strauss, while Aaron Mille

Updated on: December 18,2023 19

Is the next big step in cancer therapy personalized vaccines?

byUniversity of California - San DiegoEzra Cohen, MD, UC San Diego Health physician scientist, administered the first-of-its-kind personalized cancer vaccine to Tamara Strauss, while Aaron Mille

Updated on:December 18,2023 19

SABCS: Updated analysis confirms endocrine therapy effective with/without chemo

by Elana GotkineFor patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, node-negative early breast cancer (EBC) with a 21-gene recurrence score (RS)

Updated on: December 17,2023 10

SABCS: Updated analysis confirms endocrine therapy effective with/without chemo

by Elana GotkineFor patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, node-negative early breast cancer (EBC) with a 21-gene recurrence score (RS)

Updated on:December 17,2023 10

Researchers elucidate roles of TP63 and SOX2 in squamous cell cancer progression

byNational University of SingaporeCredit: CC0 Public DomainSquamous cell carcinomas (SCCs) are aggressive malignancies arising from the squamous epithelium of various organs, such as the esophag

Updated on: December 18,2023 20

Researchers elucidate roles of TP63 and SOX2 in squamous cell cancer progression

byNational University of SingaporeCredit: CC0 Public DomainSquamous cell carcinomas (SCCs) are aggressive malignancies arising from the squamous epithelium of various organs, such as the esophag

Updated on:December 18,2023 20