Topography of the genome influences where cancer mutations thrive, study shows

byUniversity of California - San DiegoJust as different terrains on Earth foster distinct ecosystems, certain topographic features in the genome seem to provide an environment for specific mutat

Updated on: January 22,2024 12

Topography of the genome influences where cancer mutations thrive, study shows

byUniversity of California - San DiegoJust as different terrains on Earth foster distinct ecosystems, certain topographic features in the genome seem to provide an environment for specific mutat

Updated on:January 22,2024 12

Faulty DNA repair may lead to BRCA-linked cancers

byWeill Cornell Medical CollegeStalled replication forks (yellow arrows) are detected at the BRCA1 gene in cells containing a BRCA1 germline mutation. Credit: Weill Cornell MedicineError-prone D

Updated on: December 20,2023 10

Faulty DNA repair may lead to BRCA-linked cancers

byWeill Cornell Medical CollegeStalled replication forks (yellow arrows) are detected at the BRCA1 gene in cells containing a BRCA1 germline mutation. Credit: Weill Cornell MedicineError-prone D

Updated on:December 20,2023 10

Uncovering how air pollution causes lung cancer

byCORDISCredit: AI-generated imageCigarette smoking is the No. 1 risk factor for lung cancer. Exposure to second-hand smoke can also increase the risk of lung cancer. This is what scientists hav

Updated on: December 26,2023 9

Uncovering how air pollution causes lung cancer

byCORDISCredit: AI-generated imageCigarette smoking is the No. 1 risk factor for lung cancer. Exposure to second-hand smoke can also increase the risk of lung cancer. This is what scientists hav

Updated on:December 26,2023 9

Chronic health conditions associated with worse survival rates for patients with metastatic breast cancer

by Mary Clare Fischer, Dani K. Dodge-Medlin,University of MichiganDisparities in the number of chronic health conditions that Black women endure compared to other races and ethnicities contribut

Updated on: December 28,2023 9

Chronic health conditions associated with worse survival rates for patients with metastatic breast cancer

by Mary Clare Fischer, Dani K. Dodge-Medlin,University of MichiganDisparities in the number of chronic health conditions that Black women endure compared to other races and ethnicities contribut

Updated on:December 28,2023 9

UCLA researchers confirm mutations that predispose patients to rare kidney cancer syndrome

Researchers at the UCLA Jonsson Comprehensive Cancer Center have confirmed that a large number of genetic variants of unknown significance are in fact verified mutations that predispose patients to a

Updated on: November 19,2023 7

UCLA researchers confirm mutations that predispose patients to rare kidney cancer syndrome

Researchers at the UCLA Jonsson Comprehensive Cancer Center have confirmed that a large number of genetic variants of unknown significance are in fact verified mutations that predispose patients to a

Updated on:November 19,2023 7

The use of DNA biomarkers for detecting early-stage HPV-positive oropharynx cancers has limitations

byBrigham and Women's HospitalA double stranded DNA fragment. Credit: Vcpmartin/Wikimedia/ CC BY-SA 4.0Oropharynx cancers caused by human papillomavirus (HPV) have risen dramatically over th

Updated on: January 04,2024 8

The use of DNA biomarkers for detecting early-stage HPV-positive oropharynx cancers has limitations

byBrigham and Women's HospitalA double stranded DNA fragment. Credit: Vcpmartin/Wikimedia/ CC BY-SA 4.0Oropharynx cancers caused by human papillomavirus (HPV) have risen dramatically over th

Updated on:January 04,2024 8

A HER2-targeting peptide drug conjugate with better penetrability for effective breast cancer therapy

by Compuscript LtdSchematic diagram and pharmacokinetics of HER2-TP-cy5.5 and HER-TA-cy5.5 conjugate synthesis. (A) Schematic representation of the utilization of HER2-targeting peptide/antibody and C

Updated on: February 01,2024 10

A HER2-targeting peptide drug conjugate with better penetrability for effective breast cancer therapy

by Compuscript LtdSchematic diagram and pharmacokinetics of HER2-TP-cy5.5 and HER-TA-cy5.5 conjugate synthesis. (A) Schematic representation of the utilization of HER2-targeting peptide/antibody and C

Updated on:February 01,2024 10

Barriers to early clinical trial access for adolescents and young adults still exist

byEuropean Society for Medical OncologyYoung cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congre

Updated on: December 18,2023 14

Barriers to early clinical trial access for adolescents and young adults still exist

byEuropean Society for Medical OncologyYoung cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congre

Updated on:December 18,2023 14

Miami's Little Haiti joins global effort to end cervical cancer

by Verónica ZaragoviaCredit: Unsplash/CC0 Public DomainMore than 300,000 women around the world die from cervical cancer each year. In the U.S., women of Haitian descent are diagnosed with it at highe

Updated on: December 28,2023 8

Miami's Little Haiti joins global effort to end cervical cancer

by Verónica ZaragoviaCredit: Unsplash/CC0 Public DomainMore than 300,000 women around the world die from cervical cancer each year. In the U.S., women of Haitian descent are diagnosed with it at highe

Updated on:December 28,2023 8

Oncologists demand more education on the use of biosimilars. ESMO takes action

byEuropean Society for Medical OncologyCredit: CC0 Public DomainBiological medicines are responsible for some of the most promising innovations in cancer treatment, including immunotherapy, targ

Updated on: December 18,2023 16

Oncologists demand more education on the use of biosimilars. ESMO takes action

byEuropean Society for Medical OncologyCredit: CC0 Public DomainBiological medicines are responsible for some of the most promising innovations in cancer treatment, including immunotherapy, targ

Updated on:December 18,2023 16

Fat fuels aggressive brain cancers

byCardiff UniversityGliobastoma (astrocytoma) WHO grade IV—MRI coronal view, post contrast. 15 year old boy. Credit: Christaras A/ Wikipedia.Fat is powering tumour growth in brain cancer, finds

Updated on: December 18,2023 19

Fat fuels aggressive brain cancers

byCardiff UniversityGliobastoma (astrocytoma) WHO grade IV—MRI coronal view, post contrast. 15 year old boy. Credit: Christaras A/ Wikipedia.Fat is powering tumour growth in brain cancer, finds

Updated on:December 18,2023 19

Identification of colony stimulating factor 1 receptor offers new strategy for cancer immunotherapy

by Zhang Nannan,Chinese Academy of SciencesIHMT-CSF1R-833 alters the macrophage polarization in M2 macrophages derived from RAW264.7 cells by inducing the M1 macrophage phenotype. Credit: Liang

Updated on: December 25,2023 6

Identification of colony stimulating factor 1 receptor offers new strategy for cancer immunotherapy

by Zhang Nannan,Chinese Academy of SciencesIHMT-CSF1R-833 alters the macrophage polarization in M2 macrophages derived from RAW264.7 cells by inducing the M1 macrophage phenotype. Credit: Liang

Updated on:December 25,2023 6