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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Structural insights reveal how SPOP protein contributes to cancer

Structural insights reveal how SPOP protein contributes to cancer

bySt. Jude Children's Research HospitalL to R: L to R: Brian O’Flynn, Ph.D., Matthew Cuneo, Ph.D., and Tanja Mittag, Ph.D. Credit: St. Jude Children's Research HospitalSPOP is the most m

Structural insights reveal how SPOP protein contributes to cancer

bySt. Jude Children's Research HospitalL to R: L to R: Brian O’Flynn, Ph.D., Matthew Cuneo, Ph.D., and Tanja Mittag, Ph.D. Credit: St. Jude Children's Research HospitalSPOP is the most m
Saccharin derivatives give cancer cells a not-so-sweet surprise

Saccharin derivatives give cancer cells a not-so-sweet surprise

byAmerican Chemical SocietyCredit: American Chemical SocietySaccharin received a bad rap after studies in the 1970s linked consumption of large amounts of the artificial sweetener to bladder can

Saccharin derivatives give cancer cells a not-so-sweet surprise

byAmerican Chemical SocietyCredit: American Chemical SocietySaccharin received a bad rap after studies in the 1970s linked consumption of large amounts of the artificial sweetener to bladder can
Survival in Primary Hemophagocytic Lymphohistiocytosis Can Be as High as 100%

Survival in Primary Hemophagocytic Lymphohistiocytosis Can Be as High as 100%

February 2024Lara C. Pullen, PhDResults from a contemporary standard-of-care study of patients with primary hemophagocytic lymphohistiocytosis (pHLH) reveal that firstline etoposide-based therapy is m

Survival in Primary Hemophagocytic Lymphohistiocytosis Can Be as High as 100%

February 2024Lara C. Pullen, PhDResults from a contemporary standard-of-care study of patients with primary hemophagocytic lymphohistiocytosis (pHLH) reveal that firstline etoposide-based therapy is m
Finding the optimal combination of anticancer drug administration for the conditioning of cord blood transplantation

Finding the optimal combination of anticancer drug administration for the conditioning of cord blood transplantation

by University of TsukubaCredit: Unsplash/CC0 Public DomainAllogeneic hematopoietic stem-cell transplantation (allo-HSCT) can cure hematopoietic diseases, such as acute myeloid leukemia. Cord bloo

Finding the optimal combination of anticancer drug administration for the conditioning of cord blood transplantation

by University of TsukubaCredit: Unsplash/CC0 Public DomainAllogeneic hematopoietic stem-cell transplantation (allo-HSCT) can cure hematopoietic diseases, such as acute myeloid leukemia. Cord bloo
Fibroblasts involved in healing spur tumor growth in cancer

Fibroblasts involved in healing spur tumor growth in cancer

byTel Aviv UniversityCredit: Tel Aviv UniversityThe connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the

Fibroblasts involved in healing spur tumor growth in cancer

byTel Aviv UniversityCredit: Tel Aviv UniversityThe connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the
Intravesical gemcitabine/docetaxel as an alternative therapy for patients with non-muscle-invasive bladder cancer

Intravesical gemcitabine/docetaxel as an alternative therapy for patients with non-muscle-invasive bladder cancer

by Michael A. O'Donnell and Mohamad Abou Chakra , Medical XpressNMIBC: non-muscle invasive bladder cancer; BCG: Bacillus Calmette-Guérin; Gem: gemcitabine; Doce: docetaxel. Parts of the figure wer

Intravesical gemcitabine/docetaxel as an alternative therapy for patients with non-muscle-invasive bladder cancer

by Michael A. O'Donnell and Mohamad Abou Chakra , Medical XpressNMIBC: non-muscle invasive bladder cancer; BCG: Bacillus Calmette-Guérin; Gem: gemcitabine; Doce: docetaxel. Parts of the figure wer
Unveiling the non-canonical functions of EZH2 in prostate cancer

Unveiling the non-canonical functions of EZH2 in prostate cancer

by Impact Journals LLCProstate cancer cells. Credit: NIH Image GalleryA new editorial paper was published inOncotargettitled "Unveiling the non-canonical functions of EZH2 in prostate

Unveiling the non-canonical functions of EZH2 in prostate cancer

by Impact Journals LLCProstate cancer cells. Credit: NIH Image GalleryA new editorial paper was published inOncotargettitled "Unveiling the non-canonical functions of EZH2 in prostate
Localized genetic mutations may serve as biomarker for wide range of cancers

Localized genetic mutations may serve as biomarker for wide range of cancers

by Melissa Rohman,Northwestern UniversityCredit: Brianna Monroe/Northwestern UniversityA team of Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind

Localized genetic mutations may serve as biomarker for wide range of cancers

by Melissa Rohman,Northwestern UniversityCredit: Brianna Monroe/Northwestern UniversityA team of Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind
Enhanced tumor modeling using Laponite bioinks for 3D bioprinting

Enhanced tumor modeling using Laponite bioinks for 3D bioprinting

by Terasaki Institute for Biomedical InnovationScientists from the Terasaki Institute for Biomedical Innovation (TIBI) have formulated a tuneable, nanoengineered bioink for tumor modeling which contai

Enhanced tumor modeling using Laponite bioinks for 3D bioprinting

by Terasaki Institute for Biomedical InnovationScientists from the Terasaki Institute for Biomedical Innovation (TIBI) have formulated a tuneable, nanoengineered bioink for tumor modeling which contai
Genomic testing can identify African American prostate cancer patients who have high-risk disease

Genomic testing can identify African American prostate cancer patients who have high-risk disease

byH. Lee Moffitt Cancer Center & Research InstituteCredit: Unsplash/CC0 Public DomainAfrican American men tend to be diagnosed more frequently with prostate cancer and have higher mortality

Genomic testing can identify African American prostate cancer patients who have high-risk disease

byH. Lee Moffitt Cancer Center & Research InstituteCredit: Unsplash/CC0 Public DomainAfrican American men tend to be diagnosed more frequently with prostate cancer and have higher mortality
Study provides insights into early breast cancer development in individuals with BRCA2 mutations

Study provides insights into early breast cancer development in individuals with BRCA2 mutations

by National University of SingaporeBrca2mut/WTmammary glands are morphologically similar to wild-type mammary glands in young and aged mice. Credit:Nature Communications(2023).

Study provides insights into early breast cancer development in individuals with BRCA2 mutations

by National University of SingaporeBrca2mut/WTmammary glands are morphologically similar to wild-type mammary glands in young and aged mice. Credit:Nature Communications(2023).
Severe mental illness linked to low attendance at cancer screening

Severe mental illness linked to low attendance at cancer screening

byUniversity of SurreyCredit: CC0 Public DomainPeople with severe mental illness are less likely to attend cancer screening compared to those who do not have such conditions, according to new re

Severe mental illness linked to low attendance at cancer screening

byUniversity of SurreyCredit: CC0 Public DomainPeople with severe mental illness are less likely to attend cancer screening compared to those who do not have such conditions, according to new re