Skeletal muscle regeneration discovery paves the way for targeted therapies for muscle disorders

by Laurie Fickman,University of HoustonLoss of IRE1α in satellite cells inhibits the formation of regenerating myofibers. Credit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00197-4Re

Updated on: July 23,2024

Skeletal muscle regeneration discovery paves the way for targeted therapies for muscle disorders

by Laurie Fickman,University of HoustonLoss of IRE1α in satellite cells inhibits the formation of regenerating myofibers. Credit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00197-4Re

Updated on:July 23,2024

Using meds to manage your arthritis pain: An overview

by Cara MurezMillions of Americans suffer from arthritis, and many reach for medication to ease their joint pain and inflammation.The options might seem overwhelming, though. Here, the Arthritis Found

Updated on: June 01,2024

Using meds to manage your arthritis pain: An overview

by Cara MurezMillions of Americans suffer from arthritis, and many reach for medication to ease their joint pain and inflammation.The options might seem overwhelming, though. Here, the Arthritis Found

Updated on:June 01,2024

Osteoarthritis (Degenerative Arthritis): Symptoms and Treatment

Osteoarthritis (Degenerative Arthritis): Symptoms and TreatmentEarly Treatment Can Help ImmenselyByCarol EusticeUpdated on September 28, 2023Medically reviewed byAnita C. Chand

Updated on: June 12,2024

Osteoarthritis (Degenerative Arthritis): Symptoms and Treatment

Osteoarthritis (Degenerative Arthritis): Symptoms and TreatmentEarly Treatment Can Help ImmenselyByCarol EusticeUpdated on September 28, 2023Medically reviewed byAnita C. Chand

Updated on:June 12,2024

Investigational BCMA-Directed CAR T-Cell Therapy for R/R Multiple Myeloma Provides Deep Responses, Low Toxicity

October 2023Katie RobinsonA fractionated dose of ARI0002hm, an investigational autologous chimeric antigen receptor (CAR) T-cell therapy targeting B-cell maturation antigen (BCMA), combined with a boo

Updated on: February 18,2024

Investigational BCMA-Directed CAR T-Cell Therapy for R/R Multiple Myeloma Provides Deep Responses, Low Toxicity

October 2023Katie RobinsonA fractionated dose of ARI0002hm, an investigational autologous chimeric antigen receptor (CAR) T-cell therapy targeting B-cell maturation antigen (BCMA), combined with a boo

Updated on:February 18,2024

New mechanism uncovered behind osteoarthritis could inform new treatments

by Mass General BrighamAge-related matrix stiffening in articular cartilage initiates pathogenic mechanotransductive signaling, driving chondrocyte dysfunction as well as disrupted cartilage integrity

Updated on: June 06,2024

New mechanism uncovered behind osteoarthritis could inform new treatments

by Mass General BrighamAge-related matrix stiffening in articular cartilage initiates pathogenic mechanotransductive signaling, driving chondrocyte dysfunction as well as disrupted cartilage integrity

Updated on:June 06,2024

Inhibition of oxidative phosphorylation points to new potential treatment for an intractable genetic disease

byKyoto UniversityInhibition of injury-induced chondrogenesis and heterotopic ossification by IACS. A, Gene set for chondrogenic differentiation. B, Chondrogenic differentiation 7 days after pin

Updated on: March 27,2024

Inhibition of oxidative phosphorylation points to new potential treatment for an intractable genetic disease

byKyoto UniversityInhibition of injury-induced chondrogenesis and heterotopic ossification by IACS. A, Gene set for chondrogenic differentiation. B, Chondrogenic differentiation 7 days after pin

Updated on:March 27,2024

An Overview of Orthopedic Physical Therapy

An Overview of Orthopedic Physical TherapyByBrett Sears, PTUpdated on June 20, 2022Medically reviewed byMohamad Hassan, PTIf you have an injury or illness that affects your bon

Updated on: June 12,2024

An Overview of Orthopedic Physical Therapy

An Overview of Orthopedic Physical TherapyByBrett Sears, PTUpdated on June 20, 2022Medically reviewed byMohamad Hassan, PTIf you have an injury or illness that affects your bon

Updated on:June 12,2024

Scores developed for risk stratification in inflammatory arthritis

by Elana GotkineA simple and a comprehensive score has been developed for persons at risk for inflammatory arthritis, according to a study published online Aug. 1 in theAnnals of Internal Medici

Updated on: January 29,2024

Scores developed for risk stratification in inflammatory arthritis

by Elana GotkineA simple and a comprehensive score has been developed for persons at risk for inflammatory arthritis, according to a study published online Aug. 1 in theAnnals of Internal Medici

Updated on:January 29,2024

A prosthesis driven by the nervous system helps people with amputation walk naturally

by Anne Trafton,Massachusetts Institute of TechnologyNeuroprosthesis. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-02994-9State-of-the-art prosthetic limbs can help people w

Updated on: July 08,2024

A prosthesis driven by the nervous system helps people with amputation walk naturally

by Anne Trafton,Massachusetts Institute of TechnologyNeuroprosthesis. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-02994-9State-of-the-art prosthetic limbs can help people w

Updated on:July 08,2024

Opto-RANK: A light switch for osteoclasts that could activate bone repair

byTokyo Medical and Dental UniversityA representative micrograph of osteoclast differentiation and activity in response to irradiation with blue light. Numerous small pits formed on the bone-lik

Updated on: March 27,2024

Opto-RANK: A light switch for osteoclasts that could activate bone repair

byTokyo Medical and Dental UniversityA representative micrograph of osteoclast differentiation and activity in response to irradiation with blue light. Numerous small pits formed on the bone-lik

Updated on:March 27,2024

Study shows AFL players' hip issues begin in early career

by Elaine Cooney,La Trobe UniversityCredit: Unsplash/CC0 Public DomainResearchers from La Trobe University studied 58 pain-free male Australian Football League (AFL) draftees, finding that nearl

Updated on: September 14,2024

Study shows AFL players' hip issues begin in early career

by Elaine Cooney,La Trobe UniversityCredit: Unsplash/CC0 Public DomainResearchers from La Trobe University studied 58 pain-free male Australian Football League (AFL) draftees, finding that nearl

Updated on:September 14,2024

Gene variant links trigger finger and carpal tunnel syndrome

by University of OxfordAssociation between trigger finger and carpal tunnel syndrome. Data from UK Biobank. (A) Overlap between trigger finger and carpal tunnel syndrome in UK Biobank, annotated

Updated on: June 06,2024

Gene variant links trigger finger and carpal tunnel syndrome

by University of OxfordAssociation between trigger finger and carpal tunnel syndrome. Data from UK Biobank. (A) Overlap between trigger finger and carpal tunnel syndrome in UK Biobank, annotated

Updated on:June 06,2024