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Researchers turn the body's B cells into tiny surveillance machines, antibody factories

Researchers turn the body's B cells into tiny surveillance machines, antibody factories

by Leigh Hopper,University of Southern CaliforniaGenome editing at the constant region of the IgH locus. a, Antibody H chains are encoded by a rearranged variable domain (VH) spliced to a consta
Updated on: July 30,2024
Researchers turn the body's B cells into tiny surveillance machines, antibody factories

Researchers turn the body's B cells into tiny surveillance machines, antibody factories

by Leigh Hopper,University of Southern CaliforniaGenome editing at the constant region of the IgH locus. a, Antibody H chains are encoded by a rearranged variable domain (VH) spliced to a consta
Updated on:July 30,2024
New lens system for endoscopes could allow physicians to see inside the body like never before

New lens system for endoscopes could allow physicians to see inside the body like never before

by Wayne Gillam,University of Washington - Department of Electrical & Computer EngineeringAn illustration of the endoscope lens system designed by UW ECE and Physics Professor Arka Majumdar
Updated on: November 23,2024
New lens system for endoscopes could allow physicians to see inside the body like never before

New lens system for endoscopes could allow physicians to see inside the body like never before

by Wayne Gillam,University of Washington - Department of Electrical & Computer EngineeringAn illustration of the endoscope lens system designed by UW ECE and Physics Professor Arka Majumdar
Updated on:November 23,2024
Research shows spike gene mutations do not correlate with increased SARS-CoV-2 variant severity

Research shows spike gene mutations do not correlate with increased SARS-CoV-2 variant severity

byUniversity of North Carolina at CharlotteA visual representation of the novelin silicomethodology used in the study: prediction of protein structure, molecular docking simulations,
Updated on: July 30,2024
Research shows spike gene mutations do not correlate with increased SARS-CoV-2 variant severity

Research shows spike gene mutations do not correlate with increased SARS-CoV-2 variant severity

byUniversity of North Carolina at CharlotteA visual representation of the novelin silicomethodology used in the study: prediction of protein structure, molecular docking simulations,
Updated on:July 30,2024
New resource maps gene-disease links across common conditions, paving the way for personalized medicine

New resource maps gene-disease links across common conditions, paving the way for personalized medicine

byHebrew University of JerusalemCredit: Pixabay/CC0 Public DomainA new study introduces an innovative tool for exploring gene-disease connections: the PWAS Hub. This resource is based on the nov
Updated on: November 22,2024
New resource maps gene-disease links across common conditions, paving the way for personalized medicine

New resource maps gene-disease links across common conditions, paving the way for personalized medicine

byHebrew University of JerusalemCredit: Pixabay/CC0 Public DomainA new study introduces an innovative tool for exploring gene-disease connections: the PWAS Hub. This resource is based on the nov
Updated on:November 22,2024
Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

byUniversity of TsukubaCredit: Anna Shvets from PexelsClinical trials for cancer drugs have three stages, Phase I–III, before marketing, each with different evaluation items. However, there is n
Updated on: April 28,2024
Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

Difficulties of setting efficacy endpoints in early-stage clinical trials of brain tumor drugs

byUniversity of TsukubaCredit: Anna Shvets from PexelsClinical trials for cancer drugs have three stages, Phase I–III, before marketing, each with different evaluation items. However, there is n
Updated on:April 28,2024
Embryo's signaling mechanism may promote healthy aging, combat neurodegenerative diseases

Embryo's signaling mechanism may promote healthy aging, combat neurodegenerative diseases

by Melissa Rohman,Northwestern UniversityNHR-49 is important in multiple paradigms of stress resilience. (A) Heat stress survival of wild type and daf-2(e1370) mutants crossed into nhr-49(nr2041
Updated on: July 08,2024
Embryo's signaling mechanism may promote healthy aging, combat neurodegenerative diseases

Embryo's signaling mechanism may promote healthy aging, combat neurodegenerative diseases

by Melissa Rohman,Northwestern UniversityNHR-49 is important in multiple paradigms of stress resilience. (A) Heat stress survival of wild type and daf-2(e1370) mutants crossed into nhr-49(nr2041
Updated on:July 08,2024
Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

bySt. Jude Children's Research HospitalA glutamine metabolic switch is essential for erythropoiesis. Credit:Science(2024). DOI: 10.1126/science.adh9215Blood stem cells develop th
Updated on: December 03,2024
Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

Glutamine metabolic switch is key to red blood cell development and disease, researchers reveal

bySt. Jude Children's Research HospitalA glutamine metabolic switch is essential for erythropoiesis. Credit:Science(2024). DOI: 10.1126/science.adh9215Blood stem cells develop th
Updated on:December 03,2024
New research finds that exposure to odorant-based HDAC inhibitors could delay neurological disease onset

New research finds that exposure to odorant-based HDAC inhibitors could delay neurological disease onset

byUniversity of California - RiversideRemote exposure to HDACi volatile alters gene expression in an invertebrate and vertebrate. Credit:eLife(2024). DOI: 10.7554/eLife.86823.3Imagin
Updated on: March 13,2024
New research finds that exposure to odorant-based HDAC inhibitors could delay neurological disease onset

New research finds that exposure to odorant-based HDAC inhibitors could delay neurological disease onset

byUniversity of California - RiversideRemote exposure to HDACi volatile alters gene expression in an invertebrate and vertebrate. Credit:eLife(2024). DOI: 10.7554/eLife.86823.3Imagin
Updated on:March 13,2024
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