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Scientists improve the equation in FDA guidance predicting drug interactions

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und
Study of type 2 diabetes medications show differences in medication acceptance, quality-of-life, insulin secretion

Study of type 2 diabetes medications show differences in medication acceptance, quality-of-life, insulin secretion

byLouisiana State UniversityCredit: Pixabay/CC0 Public DomainDiabetes affects more than 1 in 10—or more than 38 million—Americans. People with diabetes who keep their blood sugar levels in the n

Study of type 2 diabetes medications show differences in medication acceptance, quality-of-life, insulin secretion

byLouisiana State UniversityCredit: Pixabay/CC0 Public DomainDiabetes affects more than 1 in 10—or more than 38 million—Americans. People with diabetes who keep their blood sugar levels in the n
Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic
Combined antibiotics more effective against Lyme disease: Study

Combined antibiotics more effective against Lyme disease: Study

by Leslie Tate,Tulane UniversityThe study findings could pave the way for improved Lyme disease treatments, particularly in persistent cases, said lead researcher Monica Embers, PhD, associate p

Combined antibiotics more effective against Lyme disease: Study

by Leslie Tate,Tulane UniversityThe study findings could pave the way for improved Lyme disease treatments, particularly in persistent cases, said lead researcher Monica Embers, PhD, associate p
The year in opioid settlements: 5 things you need to know

The year in opioid settlements: 5 things you need to know

DECEMBER 30, 2023 Editors' notesby Aneri Pattani, KFF Health NewsCredit: Pixabay/CC0 Public DomainThis year, about $1.5 billion has landed in state and local government coffers from court settleme

The year in opioid settlements: 5 things you need to know

DECEMBER 30, 2023 Editors' notesby Aneri Pattani, KFF Health NewsCredit: Pixabay/CC0 Public DomainThis year, about $1.5 billion has landed in state and local government coffers from court settleme
Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University

Innovative double-layer polysaccharide hydrogel shows promise for intestine-targeted oral delivery of probiotics

by Engineering(a) Design rationale of the DPH; (b) mechanism of intestine-targeted delivery. Credit: Wen-Can Huang et al.A research team led by Changhu Xue and Xiangzhao Mao from the Ocean University
Oropouche virus transmission to unborn child confirmed

Oropouche virus transmission to unborn child confirmed

by Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainThe first confirmed case of vertical transmission of Oropouche virus (OROV) has been reported by 23 researchers from eight distinct i

Oropouche virus transmission to unborn child confirmed

by Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainThe first confirmed case of vertical transmission of Oropouche virus (OROV) has been reported by 23 researchers from eight distinct i
Evaluating selpercatinib for the treatment of non-small cell lung cancer

Evaluating selpercatinib for the treatment of non-small cell lung cancer

by D'Or Institute for Research and EducationCredit: Unsplash/CC0 Public DomainA phase III LIBRETTO-431 multicenter study has evaluated the efficacy and safety of selpercatinib compared to control

Evaluating selpercatinib for the treatment of non-small cell lung cancer

by D'Or Institute for Research and EducationCredit: Unsplash/CC0 Public DomainA phase III LIBRETTO-431 multicenter study has evaluated the efficacy and safety of selpercatinib compared to control
FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)
Patients regain much weight after stopping new obesity drug: Study

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On
Researchers produce grafts that replicate the human ear

Researchers produce grafts that replicate the human ear

by Weill Cornell Medical CollegePictured is the intricate, left-ear plastic scaffold that was created on a 3D printer based on data from a person's ear, anterior view (left) and posterior vie

Researchers produce grafts that replicate the human ear

by Weill Cornell Medical CollegePictured is the intricate, left-ear plastic scaffold that was created on a 3D printer based on data from a person's ear, anterior view (left) and posterior vie
Scientists develop tunable organic active neural probe enabling near-sensor signal processing

Scientists develop tunable organic active neural probe enabling near-sensor signal processing

byPohang University of Science and Technology(a) Structure and functional mechanism of an implantable brain signal amplification sensor created using inkjet printing technology. (b) Magnified li

Scientists develop tunable organic active neural probe enabling near-sensor signal processing

byPohang University of Science and Technology(a) Structure and functional mechanism of an implantable brain signal amplification sensor created using inkjet printing technology. (b) Magnified li