The double-edge sword of CRISPR application for in vivo studies

by Impact Journals LLCWorkflow illustration. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28459A new editorial paper titled "The double-edge sword of CRISPR application for in vi

Updated on: January 02,2024

The double-edge sword of CRISPR application for in vivo studies

by Impact Journals LLCWorkflow illustration. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28459A new editorial paper titled "The double-edge sword of CRISPR application for in vi

Updated on:January 02,2024

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

Updated on: March 25,2024

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

Updated on:March 25,2024

Poland urges polio vaccinations for children after the virus is detected in sewage in Warsaw

Credit: Pixabay/CC0 Public DomainPoland's health authorities on Monday urgedpoliovaccinations for children after the virus was detected in Warsaw's sewage during regular tests this

Updated on: December 04,2024

Poland urges polio vaccinations for children after the virus is detected in sewage in Warsaw

Credit: Pixabay/CC0 Public DomainPoland's health authorities on Monday urgedpoliovaccinations for children after the virus was detected in Warsaw's sewage during regular tests this

Updated on:December 04,2024

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley

Updated on: January 26,2024

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley

Updated on:January 26,2024

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Updated on: April 28,2024

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Updated on:April 28,2024

Long-distance and low-attenuation magnetic energy focusing technology for deep-tissue wireless powering

by Science China Press(a1) System design of the ULFMEF developed for wireless charging of implantable electronic devices, where the ULFMEF system consisted of an IMER and an EMET. (a2) Schematic

Updated on: April 06,2024

Long-distance and low-attenuation magnetic energy focusing technology for deep-tissue wireless powering

by Science China Press(a1) System design of the ULFMEF developed for wireless charging of implantable electronic devices, where the ULFMEF system consisted of an IMER and an EMET. (a2) Schematic

Updated on:April 06,2024

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on: March 28,2024

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on:March 28,2024

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

Updated on: March 28,2024

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

Updated on:March 28,2024

Cloud-magnetic resonance imaging system in the 6G and AI era

by KeAi Communications Co.The workflow of Cloud-MRI system. Credit: Yirong Zhou., et alMagnetic resonance imaging (MRI) has played an important role in modern medical diagnosis, generating petabytes o

Updated on: July 05,2024

Cloud-magnetic resonance imaging system in the 6G and AI era

by KeAi Communications Co.The workflow of Cloud-MRI system. Credit: Yirong Zhou., et alMagnetic resonance imaging (MRI) has played an important role in modern medical diagnosis, generating petabytes o

Updated on:July 05,2024

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on: March 28,2024

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on:March 28,2024

cGAS: Sounding the alarm on self and foreign DNA

Updated on: September 24,2024

cGAS: Sounding the alarm on self and foreign DNA

Updated on:September 24,2024

The complex interplay of histone modifications and DNA methylation in epigenetic regulation

Updated on: June 01,2024

The complex interplay of histone modifications and DNA methylation in epigenetic regulation

Updated on:June 01,2024