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The fate of drug discovery in academia: Why is it so difficult?

The fate of drug discovery in academia: Why is it so difficult?

FEBRUARY 5, 2024by Impact Journals LLCA typical drug discovery and development strategy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28552A new editorial paper titled "The fate

The fate of drug discovery in academia: Why is it so difficult?

FEBRUARY 5, 2024by Impact Journals LLCA typical drug discovery and development strategy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28552A new editorial paper titled "The fate
FastGlioma: The AI Model Transforming Glioma Surgery

FastGlioma: The AI Model Transforming Glioma Surgery

Powered by artificial intelligence (AI), FastGlioma offers a new level of precision and efficiency in tumor detection, holding the potential to revolutionize glioma surgery.

FastGlioma: The AI Model Transforming Glioma Surgery

Powered by artificial intelligence (AI), FastGlioma offers a new level of precision and efficiency in tumor detection, holding the potential to revolutionize glioma surgery.
White house could punish big pharma's high prices by removing patents

White house could punish big pharma's high prices by removing patents

by Dennis ThompsonThe Biden administration is flexing some federal muscle in its push for lower drug prices, warning pharmaceutical companies that it might use its authority to cancel patent protectio

White house could punish big pharma's high prices by removing patents

by Dennis ThompsonThe Biden administration is flexing some federal muscle in its push for lower drug prices, warning pharmaceutical companies that it might use its authority to cancel patent protectio
Mechanical engineers develop miniaturized, hydrogel-based electric generators for biomedical devices

Mechanical engineers develop miniaturized, hydrogel-based electric generators for biomedical devices

by The University of Hong KongThe hydrogel electric generator and its working mechanism. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-45931-7Mechanoelectrical energy conversion offers

Mechanical engineers develop miniaturized, hydrogel-based electric generators for biomedical devices

by The University of Hong KongThe hydrogel electric generator and its working mechanism. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-45931-7Mechanoelectrical energy conversion offers
New frontier in biomedical engineering: Protein coacervates engineered into adhesive for unprecedented skin repair speed

New frontier in biomedical engineering: Protein coacervates engineered into adhesive for unprecedented skin repair speed

by Engineering(a) Schematic diagram of ECM composition. Elastin and growth factor are important components of the ECM. (b) Construction and expression of the protein. (c) Preparation of the EED adhesi

New frontier in biomedical engineering: Protein coacervates engineered into adhesive for unprecedented skin repair speed

by Engineering(a) Schematic diagram of ECM composition. Elastin and growth factor are important components of the ECM. (b) Construction and expression of the protein. (c) Preparation of the EED adhesi
A molecular route to decoding synaptic specificity and nerve cell communication

A molecular route to decoding synaptic specificity and nerve cell communication

by Tokyo Institute of TechnologyThis study provides insights into the molecular mechanisms underlying the neuronal synaptic interaction. Credit: Tokyo TechNeurons or nerve cells are the fundament

A molecular route to decoding synaptic specificity and nerve cell communication

by Tokyo Institute of TechnologyThis study provides insights into the molecular mechanisms underlying the neuronal synaptic interaction. Credit: Tokyo TechNeurons or nerve cells are the fundament
Researchers race to develop Paxlovid replacement

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor
Study supports use of cystic fibrosis drug in infants from four weeks of age

Study supports use of cystic fibrosis drug in infants from four weeks of age

by RCSI University of Medicine and Health SciencesCredit: Pixabay/CC0 Public DomainA cystic fibrosis drug targeting the basic defect that causes the condition has been shown to be safe and effective i

Study supports use of cystic fibrosis drug in infants from four weeks of age

by RCSI University of Medicine and Health SciencesCredit: Pixabay/CC0 Public DomainA cystic fibrosis drug targeting the basic defect that causes the condition has been shown to be safe and effective i
Clinical trial highlights possible treatment for anemia in myelodysplastic neoplasms

Clinical trial highlights possible treatment for anemia in myelodysplastic neoplasms

by Anne Grimm,Leipzig UniversityCredit: Pixabay/CC0 Public DomainIn patients affected by myelodysplastic neoplasms, the body does not produce enough functional blood cells. Patients suffer from

Clinical trial highlights possible treatment for anemia in myelodysplastic neoplasms

by Anne Grimm,Leipzig UniversityCredit: Pixabay/CC0 Public DomainIn patients affected by myelodysplastic neoplasms, the body does not produce enough functional blood cells. Patients suffer from
Many antibiotic courses for common infections not in line with guidelines

Many antibiotic courses for common infections not in line with guidelines

by British Medical JournalCredit: CC0 Public DomainMany antibiotic courses prescribed for common infections treated in English primary care (general practices and community services) exceed the r

Many antibiotic courses for common infections not in line with guidelines

by British Medical JournalCredit: CC0 Public DomainMany antibiotic courses prescribed for common infections treated in English primary care (general practices and community services) exceed the r
Demystifying a key receptor in substance use and neuropsychiatric disorders

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine
CRISPR-based mapping uncovers 'switches' for immune genes central to health

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t