Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Updated on: March 14,2024

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Updated on:March 14,2024

Treating tuberculosis when antibiotics no longer work

byUniversity of CologneCredit:Cell Chemical Biology(2024). DOI: 10.1016/j.chembiol.2023.12.007Researchers have identified new antibiotic molecules that target Mycobacterium tuberculo

Updated on: January 26,2024

Treating tuberculosis when antibiotics no longer work

byUniversity of CologneCredit:Cell Chemical Biology(2024). DOI: 10.1016/j.chembiol.2023.12.007Researchers have identified new antibiotic molecules that target Mycobacterium tuberculo

Updated on:January 26,2024

Researchers identify new biomarker in quality of blood donations

by Kelsea Pieters,CU Anschutz Medical CampusCredit: CC0 Public DomainA collaborative cohort of researchers, led by University of Colorado Anschutz Medical Campus professor Angelo D'Alessandr

Updated on: March 30,2024

Researchers identify new biomarker in quality of blood donations

by Kelsea Pieters,CU Anschutz Medical CampusCredit: CC0 Public DomainA collaborative cohort of researchers, led by University of Colorado Anschutz Medical Campus professor Angelo D'Alessandr

Updated on:March 30,2024

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Updated on: January 09,2024

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Updated on:January 09,2024

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,

Updated on: April 28,2024

Study finds embryos in hungry mouse moms postpone development

byThe Company of BiologistsA mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia YeIt's challenging to sustain a pregnancy when food is short,

Updated on:April 28,2024

Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

by St. Jude Children's Research HospitalResearchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness ag

Updated on: March 06,2024

Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

by St. Jude Children's Research HospitalResearchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness ag

Updated on:March 06,2024

New frontier in biomedical engineering: Protein coacervates engineered into adhesive for unprecedented skin repair speed

by Engineering(a) Schematic diagram of ECM composition. Elastin and growth factor are important components of the ECM. (b) Construction and expression of the protein. (c) Preparation of the EED adhesi

Updated on: January 06,2024

New frontier in biomedical engineering: Protein coacervates engineered into adhesive for unprecedented skin repair speed

by Engineering(a) Schematic diagram of ECM composition. Elastin and growth factor are important components of the ECM. (b) Construction and expression of the protein. (c) Preparation of the EED adhesi

Updated on:January 06,2024

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und

Updated on: February 05,2024

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und

Updated on:February 05,2024

Researchers develop a new toolkit of fruit flies to study Zika virus

FEBRUARY 28, 2024byTexas Children's HospitalZIKV proteins cause scorable phenotypes upon overexpression in Drosophila. (A) Graphical diagram of the Zika virus (ZIKV) polyprotein, which conta

Updated on: March 29,2024

Researchers develop a new toolkit of fruit flies to study Zika virus

FEBRUARY 28, 2024byTexas Children's HospitalZIKV proteins cause scorable phenotypes upon overexpression in Drosophila. (A) Graphical diagram of the Zika virus (ZIKV) polyprotein, which conta

Updated on:March 29,2024

Migraine sufferers in England may soon be able to access a preventative drug: Atogepant

by Anna Andreou,The ConversationCredit: Unsplash/CC0 Public DomainA drug that can help prevent migraines could soon be available on the NHS. Atogepant (brand name: Aquipta) was recently recommen

Updated on: April 28,2024

Migraine sufferers in England may soon be able to access a preventative drug: Atogepant

by Anna Andreou,The ConversationCredit: Unsplash/CC0 Public DomainA drug that can help prevent migraines could soon be available on the NHS. Atogepant (brand name: Aquipta) was recently recommen

Updated on:April 28,2024

Medicare to cover Wegovy when patients also have heart disease

by Robin FosterMedicare will now cover the popular weight-loss drug Wegovy if patients using it also have heart disease, U.S. officials announced Thursday.The move comes after the U.S. Food and Drug A

Updated on: March 28,2024

Medicare to cover Wegovy when patients also have heart disease

by Robin FosterMedicare will now cover the popular weight-loss drug Wegovy if patients using it also have heart disease, U.S. officials announced Thursday.The move comes after the U.S. Food and Drug A

Updated on:March 28,2024

Study identifies factors that affect antibiotic prescribing for acne

by Elana GotkineMultiple salient factors affect long-term antibiotic prescribing practices for acne, according to a studypublishedinJAMA Dermatology.Ronnie A. Festok, from the Emory

Updated on: April 28,2024

Study identifies factors that affect antibiotic prescribing for acne

by Elana GotkineMultiple salient factors affect long-term antibiotic prescribing practices for acne, according to a studypublishedinJAMA Dermatology.Ronnie A. Festok, from the Emory

Updated on:April 28,2024