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Breakthroughs
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Off-label use of a common antibiotic to treat muscular dystrophy

Off-label use of a common antibiotic to treat muscular dystrophy

byOsaka UniversityMechanisms of molecular pathology and erythromycin treatment in myotonic dystrophy type 1 In myotonic dystrophy type 1, aberrant RNA transcribed from the mutant DMPK gene leads

Off-label use of a common antibiotic to treat muscular dystrophy

byOsaka UniversityMechanisms of molecular pathology and erythromycin treatment in myotonic dystrophy type 1 In myotonic dystrophy type 1, aberrant RNA transcribed from the mutant DMPK gene leads
Researchers make mice a more powerful tool to study a wide range of human diseases

Researchers make mice a more powerful tool to study a wide range of human diseases

byJackson LaboratoryThe new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles ce

Researchers make mice a more powerful tool to study a wide range of human diseases

byJackson LaboratoryThe new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles ce
Male infertility genetic study improves molecular diagnostics and personalized management of patients

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these

Male infertility genetic study improves molecular diagnostics and personalized management of patients

by Estonian Research CouncilDNA samples in Estonian Biobank. Photo by Renee Altrov. Credit: Renee AltrovApproximately one in seven couples face difficulties conceiving a child naturally. Half of these
Clinical trial: New dual therapy could revolutionize treatment of urothelial and bladder cancers

Clinical trial: New dual therapy could revolutionize treatment of urothelial and bladder cancers

by Georgia Gowing,Macquarie UniversityDr. Alison Zhang. Credit: Macquarie UniversityAn international clinical trial of a treatment for advanced urothelial cancer has found a new dual therapy can

Clinical trial: New dual therapy could revolutionize treatment of urothelial and bladder cancers

by Georgia Gowing,Macquarie UniversityDr. Alison Zhang. Credit: Macquarie UniversityAn international clinical trial of a treatment for advanced urothelial cancer has found a new dual therapy can
'Low-intensity' blood stem cell transplants for sickle cell appear safe for lung health

'Low-intensity' blood stem cell transplants for sickle cell appear safe for lung health

byNational Institutes of HealthCredit: National Institutes of HealthSo-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants,

'Low-intensity' blood stem cell transplants for sickle cell appear safe for lung health

byNational Institutes of HealthCredit: National Institutes of HealthSo-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants,
RSV hospitalizations linked to considerable burden in adults

RSV hospitalizations linked to considerable burden in adults

by Elana GotkineRespiratory syncytial virus (RSV) is associated with a considerable burden of hospitalizations, intensive care unit (ICU) admissions, and in-hospital deaths among adults, according to

RSV hospitalizations linked to considerable burden in adults

by Elana GotkineRespiratory syncytial virus (RSV) is associated with a considerable burden of hospitalizations, intensive care unit (ICU) admissions, and in-hospital deaths among adults, according to
World-first human trial finds arthritis drug can suppress progression of type 1 diabetes

World-first human trial finds arthritis drug can suppress progression of type 1 diabetes

DECEMBER 6, 2023bySt Vincent's Institute of Medical ResearchCredit: CC0 Public DomainResearchers at St Vincent's Institute of Medical Research (SVI) in Melbourne have shown that a common

World-first human trial finds arthritis drug can suppress progression of type 1 diabetes

DECEMBER 6, 2023bySt Vincent's Institute of Medical ResearchCredit: CC0 Public DomainResearchers at St Vincent's Institute of Medical Research (SVI) in Melbourne have shown that a common
Music and genomes: Beethoven's genes put to the test

Music and genomes: Beethoven's genes put to the test

by Ina Wittmann,Max Planck SocietyThe analysis of Beethoven's DNA shows possibilities and limits of predictions in the field of genetics. Credit: MPIEA / F. BernoullyTo what extent are excep

Music and genomes: Beethoven's genes put to the test

by Ina Wittmann,Max Planck SocietyThe analysis of Beethoven's DNA shows possibilities and limits of predictions in the field of genetics. Credit: MPIEA / F. BernoullyTo what extent are excep
Study highlights impact of aldehydes on DNA damage and aging

Study highlights impact of aldehydes on DNA damage and aging

byNagoya UniversityHistones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. Credit: Reiko Matsushi

Study highlights impact of aldehydes on DNA damage and aging

byNagoya UniversityHistones are crosslinked with DNA (histone-DPC) following formaldehyde exposure, leading to the malfunction of cellular processes such as transcription. Credit: Reiko Matsushi
How to make mRNA therapeutics safe from the start

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern
Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease
Meningitis may have a much greater impact on child mortality than previously thought

Meningitis may have a much greater impact on child mortality than previously thought

byBarcelona Institute for Global HealthCredit: Pixabay/CC0 Public DomainMeningitis contributes to higher child mortality rates than estimated by the WHO, according to a new study by the CHAMPS n

Meningitis may have a much greater impact on child mortality than previously thought

byBarcelona Institute for Global HealthCredit: Pixabay/CC0 Public DomainMeningitis contributes to higher child mortality rates than estimated by the WHO, according to a new study by the CHAMPS n