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Hematology&Oncology
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Common medicines may influence CRISPR therapy outcomes and precision cancer treatment

Common medicines may influence CRISPR therapy outcomes and precision cancer treatment

byMax Planck SocietyDrug screening for DSB repair pathway modulators. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-67243-0In a new study, scientists at the Max Planck Institute for Evol

Common medicines may influence CRISPR therapy outcomes and precision cancer treatment

byMax Planck SocietyDrug screening for DSB repair pathway modulators. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-67243-0In a new study, scientists at the Max Planck Institute for Evol
Thick melanoma tumors may be linked to poorer survival than some metastatic cases

Thick melanoma tumors may be linked to poorer survival than some metastatic cases

byUniversity of GothenburgCredit: Unsplash/CC0 Public DomainThe current melanoma staging system does not always reflect actual survival outcomes. In some cases, patients with thick but localized tumor

Thick melanoma tumors may be linked to poorer survival than some metastatic cases

byUniversity of GothenburgCredit: Unsplash/CC0 Public DomainThe current melanoma staging system does not always reflect actual survival outcomes. In some cases, patients with thick but localized tumor
Engineered dendritic cells boost cancer immunotherapy

Engineered dendritic cells boost cancer immunotherapy

byEcole Polytechnique Federale de LausanneEngineered dendritic cells (right) acquire tumor-derived extracellular vesicles that contain cancer antigens (left), stimulating anti-tumor immunity. Credit:

Engineered dendritic cells boost cancer immunotherapy

byEcole Polytechnique Federale de LausanneEngineered dendritic cells (right) acquire tumor-derived extracellular vesicles that contain cancer antigens (left), stimulating anti-tumor immunity. Credit:
Global survey highlights challenges faced by young women with advanced breast cancer

Global survey highlights challenges faced by young women with advanced breast cancer

by Associação Advanced Breast Cancer Global AllianceCredit: Unsplash/CC0 Public DomainNearly half of all women aged younger than 40 who live with advanced breast cancer have children under the age of

Global survey highlights challenges faced by young women with advanced breast cancer

by Associação Advanced Breast Cancer Global AllianceCredit: Unsplash/CC0 Public DomainNearly half of all women aged younger than 40 who live with advanced breast cancer have children under the age of
Cause or effect? Study answers question about gene linked with colorectal cancer

Cause or effect? Study answers question about gene linked with colorectal cancer

by Jacqueline Mitchell,Harvard Medical SchoolIn mice lacking the COSMC gene, gut cells underwent vast changes in appearance and gene activity that predisposed them to develop into colorectal cancer. H

Cause or effect? Study answers question about gene linked with colorectal cancer

by Jacqueline Mitchell,Harvard Medical SchoolIn mice lacking the COSMC gene, gut cells underwent vast changes in appearance and gene activity that predisposed them to develop into colorectal cancer. H
How scientists are hacking bacteria to treat cancer, self-destruct, then vanish without a trace

How scientists are hacking bacteria to treat cancer, self-destruct, then vanish without a trace

by Josephine Wright, Susan Woods,The ConversationCredit: CC0 Public DomainBacteria are rapidly emerging as anew classof "living medicines" used to kill cancer cells.We're still a long wa

How scientists are hacking bacteria to treat cancer, self-destruct, then vanish without a trace

by Josephine Wright, Susan Woods,The ConversationCredit: CC0 Public DomainBacteria are rapidly emerging as anew classof "living medicines" used to kill cancer cells.We're still a long wa
Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds

Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds

by Ian Demsky,Memorial Sloan Kettering Cancer CenterCredit: Unsplash/CC0 Public DomainIn most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they d

Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds

by Ian Demsky,Memorial Sloan Kettering Cancer CenterCredit: Unsplash/CC0 Public DomainIn most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they d
New risk score helps predict pancreatic cancer recurrence

New risk score helps predict pancreatic cancer recurrence

byCedars-Sinai Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainCedars-Sinai investigators, leading a multi-institutional team,

New risk score helps predict pancreatic cancer recurrence

byCedars-Sinai Medical CenterAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainCedars-Sinai investigators, leading a multi-institutional team,
Combination therapy for pancreatic cancer offers new treatment approach

Combination therapy for pancreatic cancer offers new treatment approach

by Lena Bösch,University Medical Center GöttingenMini tumor models from patient-derived tissue, known as organoids, without and with therapy. Bottom: Tumors (blue) with macrophages (yellow)—immune cel

Combination therapy for pancreatic cancer offers new treatment approach

by Lena Bösch,University Medical Center GöttingenMini tumor models from patient-derived tissue, known as organoids, without and with therapy. Bottom: Tumors (blue) with macrophages (yellow)—immune cel
Blood analysis shows whether brain cancer treatment is working

Blood analysis shows whether brain cancer treatment is working

by Kate McAlpine,University of MichiganDesign and validation ofGlioExoChip using EVPs from GBM cell lines. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-65681-4The effectiveness of chemo

Blood analysis shows whether brain cancer treatment is working

by Kate McAlpine,University of MichiganDesign and validation ofGlioExoChip using EVPs from GBM cell lines. Credit:Nature Communications(2025). DOI: 10.1038/s41467-025-65681-4The effectiveness of chemo
Cancer messenger substances disrupt muscle function and trigger muscle breakdown

Cancer messenger substances disrupt muscle function and trigger muscle breakdown

by Inka Burow,Hannover Medical SchoolDr Arnab Nayak, private lecturer, investigates the effect of pro-inflammatory messengers on muscle wasting in cancer. Credit: Tim Holler/MHHCancer patients often l

Cancer messenger substances disrupt muscle function and trigger muscle breakdown

by Inka Burow,Hannover Medical SchoolDr Arnab Nayak, private lecturer, investigates the effect of pro-inflammatory messengers on muscle wasting in cancer. Credit: Tim Holler/MHHCancer patients often l
Nanovaccine shows great promise for treating HPV-related cancers

Nanovaccine shows great promise for treating HPV-related cancers

byUTSouthwestern Medical CenterSTING nanovaccine is designed to deliver tumor antigens (Ag) and STING agonists (diABZI, PSC7A) to the tumor and secondary lymphoid organs (SLOs) to activate antit

Nanovaccine shows great promise for treating HPV-related cancers

byUTSouthwestern Medical CenterSTING nanovaccine is designed to deliver tumor antigens (Ag) and STING agonists (diABZI, PSC7A) to the tumor and secondary lymphoid organs (SLOs) to activate antit