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Hematology&Oncology
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Menopausal status influences long-term benefit from anti-hormonal treatment, study shows

Menopausal status influences long-term benefit from anti-hormonal treatment, study shows

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainToday, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low

Menopausal status influences long-term benefit from anti-hormonal treatment, study shows

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainToday, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low
Study identifies 'turncoat' cells that fight—and aid—cancer

Study identifies 'turncoat' cells that fight—and aid—cancer

by Michael Masciadrelli,Yale UniversityCirculating tumor antigen reactive T cells in patients with advanced melanoma. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-02023-4Y

Study identifies 'turncoat' cells that fight—and aid—cancer

by Michael Masciadrelli,Yale UniversityCirculating tumor antigen reactive T cells in patients with advanced melanoma. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-02023-4Y
Prior authorization delays lead to serious harm for people with cancer, nationwide survey finds

Prior authorization delays lead to serious harm for people with cancer, nationwide survey finds

byAmerican Society for Radiation OncologyCredit: American Society for Radiation OncologyA new nationwide survey of more than 750 radiation oncologists confirms that prior authorization harms peo

Prior authorization delays lead to serious harm for people with cancer, nationwide survey finds

byAmerican Society for Radiation OncologyCredit: American Society for Radiation OncologyA new nationwide survey of more than 750 radiation oncologists confirms that prior authorization harms peo
Colorectal cancer risk factors important to consider for rescreening interval

Colorectal cancer risk factors important to consider for rescreening interval

by Lori SolomonColorectal cancer (CRC) risk factors are important to consider when making decisions for colonoscopy rescreening following negative colonoscopy screening (NCS) results (no presence of C

Colorectal cancer risk factors important to consider for rescreening interval

by Lori SolomonColorectal cancer (CRC) risk factors are important to consider when making decisions for colonoscopy rescreening following negative colonoscopy screening (NCS) results (no presence of C
How individual mutations of the tumor suppressor p53 affect pancreatic carcinomas

How individual mutations of the tumor suppressor p53 affect pancreatic carcinomas

byUniversity of KonstanzMetabolic profile of p53 mutant variants in pancreatic cancer. Credit:Journal of Experimental & Clinical Cancer Research(2024). DOI: 10.1186/s13046-024-03

How individual mutations of the tumor suppressor p53 affect pancreatic carcinomas

byUniversity of KonstanzMetabolic profile of p53 mutant variants in pancreatic cancer. Credit:Journal of Experimental & Clinical Cancer Research(2024). DOI: 10.1186/s13046-024-03
Researchers discover 'crosstalk' mechanism in two key breast cancer molecules

Researchers discover 'crosstalk' mechanism in two key breast cancer molecules

byUniversity of LiverpoolIntegrin αVβ6recruits HER2 and a trafficking regulatory subnetwork comprising RAB5/RAB7A/GDI2 in HER2+ breast cancer cells. Credit:Science Advances(202

Researchers discover 'crosstalk' mechanism in two key breast cancer molecules

byUniversity of LiverpoolIntegrin αVβ6recruits HER2 and a trafficking regulatory subnetwork comprising RAB5/RAB7A/GDI2 in HER2+ breast cancer cells. Credit:Science Advances(202
Cancer risk declines in old age: New research helps explain why

Cancer risk declines in old age: New research helps explain why

by Ian Demsky,Memorial Sloan Kettering Cancer CenterAged AT2 cells exhibit reduced cell-intrinsic potential for regeneration and tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s415

Cancer risk declines in old age: New research helps explain why

by Ian Demsky,Memorial Sloan Kettering Cancer CenterAged AT2 cells exhibit reduced cell-intrinsic potential for regeneration and tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s415
How breast cancer cells survive in bone marrow after remission

How breast cancer cells survive in bone marrow after remission

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI170953A study from researchers at the University of Michigan and the Unive

How breast cancer cells survive in bone marrow after remission

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI170953A study from researchers at the University of Michigan and the Unive
DNA secreted by tumor cell extracellular vesicles prompts anti-metastatic immune response

DNA secreted by tumor cell extracellular vesicles prompts anti-metastatic immune response

byWeill Cornell Medical CollegeCredit: CC0 Public DomainSpecially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the live

DNA secreted by tumor cell extracellular vesicles prompts anti-metastatic immune response

byWeill Cornell Medical CollegeCredit: CC0 Public DomainSpecially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the live
A pair of enzymes provides insights in how pancreatic cancer cells adapt when resources are scarce

A pair of enzymes provides insights in how pancreatic cancer cells adapt when resources are scarce

bySanford-Burnham PrebysRepresentative immunohistochemical staining for p-PKCζT560and total PKCζ from clinical samples on a tissue microarray (TMA) containing 152 surgically resected human

A pair of enzymes provides insights in how pancreatic cancer cells adapt when resources are scarce

bySanford-Burnham PrebysRepresentative immunohistochemical staining for p-PKCζT560and total PKCζ from clinical samples on a tissue microarray (TMA) containing 152 surgically resected human
Computational model for drug resistance assessment can improve treatment for leukemia and lung cancer

Computational model for drug resistance assessment can improve treatment for leukemia and lung cancer

byLinnaeus UniversityCredit: Unsplash/CC0 Public DomainA new method can improve treatment for patients with chronic myeloid leukemia by predicting which medication will be most effective. The me

Computational model for drug resistance assessment can improve treatment for leukemia and lung cancer

byLinnaeus UniversityCredit: Unsplash/CC0 Public DomainA new method can improve treatment for patients with chronic myeloid leukemia by predicting which medication will be most effective. The me
Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

byUniversity of TokyoCancer cell during cell division. Credit: National Institutes of HealthTreatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addi

Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

byUniversity of TokyoCancer cell during cell division. Credit: National Institutes of HealthTreatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addi