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Hematology&Oncology
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Why anti-estrogen therapy fails in ovarian cancer, and how to make it work

Why anti-estrogen therapy fails in ovarian cancer, and how to make it work

by Darien Sutton,The Wistar InstituteMutant p53 interacts with ERα in ovarian cancer. Credit:Genes & Development(2025). DOI: 10.1101/gad.352953.125Scientists at The Wistar Institute have solved a

Why anti-estrogen therapy fails in ovarian cancer, and how to make it work

by Darien Sutton,The Wistar InstituteMutant p53 interacts with ERα in ovarian cancer. Credit:Genes & Development(2025). DOI: 10.1101/gad.352953.125Scientists at The Wistar Institute have solved a
WISDOM trial weighs risk-based cancer screening

WISDOM trial weighs risk-based cancer screening

byJustin Jackson, Medical XpressVisual abstract. Credit:JAMA(2025). DOI: 10.1001/jama.2025.24784University of California, San Francisco investigators led WISDOM, a randomized comparison of risk-based

WISDOM trial weighs risk-based cancer screening

byJustin Jackson, Medical XpressVisual abstract. Credit:JAMA(2025). DOI: 10.1001/jama.2025.24784University of California, San Francisco investigators led WISDOM, a randomized comparison of risk-based
Promising drug can inhibit aggressive breast cancer

Promising drug can inhibit aggressive breast cancer

by Erik Robinson,Oregon Health & Science UniversityGraphical abstract. Credit:Cell Reports Medicine(2025). DOI: 10.1016/j.xcrm.2025.102451New research reveals a drug developed by scientists at Ore

Promising drug can inhibit aggressive breast cancer

by Erik Robinson,Oregon Health & Science UniversityGraphical abstract. Credit:Cell Reports Medicine(2025). DOI: 10.1016/j.xcrm.2025.102451New research reveals a drug developed by scientists at Ore
Scientists show targeting cancer stem cells can prevent gastric cancer recurrence

Scientists show targeting cancer stem cells can prevent gastric cancer recurrence

byAgency for Science, Technology and Research (A*STAR), SingaporeAQP5 is a functional marker of mouse and human gastric cancer stem cells. Credit:Science(2025). DOI: 10.1126/science.adr2428Scientists

Scientists show targeting cancer stem cells can prevent gastric cancer recurrence

byAgency for Science, Technology and Research (A*STAR), SingaporeAQP5 is a functional marker of mouse and human gastric cancer stem cells. Credit:Science(2025). DOI: 10.1126/science.adr2428Scientists
DOCK10 emerges as key trigger of dangerous insulin hypersecretion in rare pancreatic tumors

DOCK10 emerges as key trigger of dangerous insulin hypersecretion in rare pancreatic tumors

byInstitute of Science TokyoThe dedicator of cytokinesis 10 (DOCK10) gene has been identified as a key driver of abnormal insulin secretion in insulinomas, as reported by researchers from Institute of

DOCK10 emerges as key trigger of dangerous insulin hypersecretion in rare pancreatic tumors

byInstitute of Science TokyoThe dedicator of cytokinesis 10 (DOCK10) gene has been identified as a key driver of abnormal insulin secretion in insulinomas, as reported by researchers from Institute of
New understanding of T cell receptors may improve cancer immunotherapies

New understanding of T cell receptors may improve cancer immunotherapies

byRockefeller UniversityThe gray portion of this schematic represents a nanodisk, where for the first time researchers were able to replicate the native membrane environment (red dots) of a T-cell rec

New understanding of T cell receptors may improve cancer immunotherapies

byRockefeller UniversityThe gray portion of this schematic represents a nanodisk, where for the first time researchers were able to replicate the native membrane environment (red dots) of a T-cell rec
Q&A: Managing menopause after cancer

Q&A: Managing menopause after cancer

byHuntsman Cancer InstituteCredit: Unsplash/CC0 Public DomainMenopause can bring a wave of physical and emotional changes—and for people with cancer, those changes can start earlier or feel more inten

Q&A: Managing menopause after cancer

byHuntsman Cancer InstituteCredit: Unsplash/CC0 Public DomainMenopause can bring a wave of physical and emotional changes—and for people with cancer, those changes can start earlier or feel more inten
Researchers identify new target to counteract muscle wasting in pancreatic cancer

Researchers identify new target to counteract muscle wasting in pancreatic cancer

by Laurie Fickman,University of HoustonSynopsis. Credit:EMBO Molecular Medicine(2025). DOI: 10.1038/s44321-025-00337-wResearchers at the University of Houston are pushing the boundaries of biomedical

Researchers identify new target to counteract muscle wasting in pancreatic cancer

by Laurie Fickman,University of HoustonSynopsis. Credit:EMBO Molecular Medicine(2025). DOI: 10.1038/s44321-025-00337-wResearchers at the University of Houston are pushing the boundaries of biomedical
Protein therapy boosts immune attack on tumors by reversing sugar 'brakes'

Protein therapy boosts immune attack on tumors by reversing sugar 'brakes'

byMassachusetts Institute of TechnologyAbLecs enhance antibody effector functions via glyco-immune checkpoint blockade. Credit:bioRxiv. DOI: 10.1101/2022.10.26.513931Researchers at MIT and Stanford Un

Protein therapy boosts immune attack on tumors by reversing sugar 'brakes'

byMassachusetts Institute of TechnologyAbLecs enhance antibody effector functions via glyco-immune checkpoint blockade. Credit:bioRxiv. DOI: 10.1101/2022.10.26.513931Researchers at MIT and Stanford Un
Prostate cancer cells use unique metabolic pathway to thrive in bone tissue

Prostate cancer cells use unique metabolic pathway to thrive in bone tissue

by Elizabeth Chapin,University of KentuckyFong with members of his lab. Credit: University of KentuckyA University of Kentucky Markey Cancer Center study reveals how prostate cancer cells adapt their

Prostate cancer cells use unique metabolic pathway to thrive in bone tissue

by Elizabeth Chapin,University of KentuckyFong with members of his lab. Credit: University of KentuckyA University of Kentucky Markey Cancer Center study reveals how prostate cancer cells adapt their
Researchers demonstrate breakthroughs in cancer treatment quality through AI-enhanced data analytics

Researchers demonstrate breakthroughs in cancer treatment quality through AI-enhanced data analytics

byUniversity of Tennessee at KnoxvilleSpatial clusters of the top six county-level features influencing LC mortality predictions using Getis-ord Gi. Credit:JCO Clinical Cancer Informatics(2025). DOI:

Researchers demonstrate breakthroughs in cancer treatment quality through AI-enhanced data analytics

byUniversity of Tennessee at KnoxvilleSpatial clusters of the top six county-level features influencing LC mortality predictions using Getis-ord Gi. Credit:JCO Clinical Cancer Informatics(2025). DOI:
New technology reduces false positives in breast ultrasounds

New technology reduces false positives in breast ultrasounds

byJohns Hopkins UniversityConventional ultrasound of breast tissue compared to the new method. Conventional ultrasound relies on the amplitude of signals, turning high and low signals into blacks, whi

New technology reduces false positives in breast ultrasounds

byJohns Hopkins UniversityConventional ultrasound of breast tissue compared to the new method. Conventional ultrasound relies on the amplitude of signals, turning high and low signals into blacks, whi