Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

byThe Mount Sinai HospitalLurbinectedin augments the anti-tumor immune response of PD-L1 blockade in immunocompetent SCLC models. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.x

Updated on: January 21,2025

Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

byThe Mount Sinai HospitalLurbinectedin augments the anti-tumor immune response of PD-L1 blockade in immunocompetent SCLC models. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.x

Updated on:January 21,2025

PIVKA-II-based model IDs liver cancer risk in hep C-related cirrhosis

by Elana GotkineAmong patients with hepatitis C virus (HCV)-related cirrhosis with sustained virological response (SVR) to direct-acting antivirals (DAAs), a serum protein induced by vitamin K absence

Updated on: December 20,2024

PIVKA-II-based model IDs liver cancer risk in hep C-related cirrhosis

by Elana GotkineAmong patients with hepatitis C virus (HCV)-related cirrhosis with sustained virological response (SVR) to direct-acting antivirals (DAAs), a serum protein induced by vitamin K absence

Updated on:December 20,2024

Cancer risk declines in old age: New research helps explain why

by Ian Demsky,Memorial Sloan Kettering Cancer CenterAged AT2 cells exhibit reduced cell-intrinsic potential for regeneration and tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s415

Updated on: December 21,2024

Cancer risk declines in old age: New research helps explain why

by Ian Demsky,Memorial Sloan Kettering Cancer CenterAged AT2 cells exhibit reduced cell-intrinsic potential for regeneration and tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s415

Updated on:December 21,2024

Highly invasive tumor hijacks neurons to grow, but a common heart medication offers hope

byChinese Academy of SciencesMouse craniopharyngioma. Credit: IGDBChinese researchers have revealed new insights into the growth of craniopharyngioma and identified a potential therapeutic treat

Updated on: January 21,2025

Highly invasive tumor hijacks neurons to grow, but a common heart medication offers hope

byChinese Academy of SciencesMouse craniopharyngioma. Credit: IGDBChinese researchers have revealed new insights into the growth of craniopharyngioma and identified a potential therapeutic treat

Updated on:January 21,2025

Vitamin E succinate shown to control tumor growth and enhance immunotherapy effects

Updated on: March 25,2025

Vitamin E succinate shown to control tumor growth and enhance immunotherapy effects

Updated on:March 25,2025

First look at neuron–tumor connections in brain illuminates formation and spread of gliomas

by Stephanie Dutchen,Harvard Medical SchoolResearchers revealed which neurons in a mouse brain, shown in red, connect to a human glioma, shown in green. Image: Annie Hsieh. Credit:Proceedi

Updated on: December 20,2024

First look at neuron–tumor connections in brain illuminates formation and spread of gliomas

by Stephanie Dutchen,Harvard Medical SchoolResearchers revealed which neurons in a mouse brain, shown in red, connect to a human glioma, shown in green. Image: Annie Hsieh. Credit:Proceedi

Updated on:December 20,2024

Reprogramming compromised immune cells to fight cancer

Updated on: March 27,2025

Reprogramming compromised immune cells to fight cancer

Updated on:March 27,2025

The hidden dangers of oral cancer

by Simon Young, DDS, MD, PhD,University of Texas Health Science Center at HoustonOral Cancer Awareness Month is observed every April, and it highlights the urgent need for early detection. According t

Updated on: June 07,2026

The hidden dangers of oral cancer

by Simon Young, DDS, MD, PhD,University of Texas Health Science Center at HoustonOral Cancer Awareness Month is observed every April, and it highlights the urgent need for early detection. According t

Updated on:June 07,2026

A pair of enzymes provides insights in how pancreatic cancer cells adapt when resources are scarce

bySanford-Burnham PrebysRepresentative immunohistochemical staining for p-PKCζT560and total PKCζ from clinical samples on a tissue microarray (TMA) containing 152 surgically resected human

Updated on: December 21,2024

A pair of enzymes provides insights in how pancreatic cancer cells adapt when resources are scarce

bySanford-Burnham PrebysRepresentative immunohistochemical staining for p-PKCζT560and total PKCζ from clinical samples on a tissue microarray (TMA) containing 152 surgically resected human

Updated on:December 21,2024

Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

byUniversity of TokyoCancer cell during cell division. Credit: National Institutes of HealthTreatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addi

Updated on: December 21,2024

Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

byUniversity of TokyoCancer cell during cell division. Credit: National Institutes of HealthTreatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addi

Updated on:December 21,2024

Cell-based immunotherapy shows promise in early clinical trial for breast cancer

byKent State UniversityBreast imaging of one trial patient before (left image) and after (right image) six weeks of experimental immunotherapy. Note diminution of area of disease (dense white ar

Updated on: December 19,2024

Cell-based immunotherapy shows promise in early clinical trial for breast cancer

byKent State UniversityBreast imaging of one trial patient before (left image) and after (right image) six weeks of experimental immunotherapy. Note diminution of area of disease (dense white ar

Updated on:December 19,2024

How individual mutations of the tumor suppressor p53 affect pancreatic carcinomas

byUniversity of KonstanzMetabolic profile of p53 mutant variants in pancreatic cancer. Credit:Journal of Experimental & Clinical Cancer Research(2024). DOI: 10.1186/s13046-024-03

Updated on: December 21,2024

How individual mutations of the tumor suppressor p53 affect pancreatic carcinomas

byUniversity of KonstanzMetabolic profile of p53 mutant variants in pancreatic cancer. Credit:Journal of Experimental & Clinical Cancer Research(2024). DOI: 10.1186/s13046-024-03

Updated on:December 21,2024