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Hematology&Oncology
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CRISPR study silences gene mutations that drive aggressive cancers

CRISPR study silences gene mutations that drive aggressive cancers

byPeter MacCallum Cancer CentreMolecular principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision. Credit:Scienc

CRISPR study silences gene mutations that drive aggressive cancers

byPeter MacCallum Cancer CentreMolecular principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision. Credit:Scienc
Breast cancer risk increases with weight gain after age 35, finds study

Breast cancer risk increases with weight gain after age 35, finds study

by Elana GotkineThe risk for breast cancer is increased with weight gain after age 35 years, according to a research letter recentlypublishedinCancer Biology & Medicine.Katherine

Breast cancer risk increases with weight gain after age 35, finds study

by Elana GotkineThe risk for breast cancer is increased with weight gain after age 35 years, according to a research letter recentlypublishedinCancer Biology & Medicine.Katherine
Abnormal prenatal blood test results could indicate hidden maternal cancers

Abnormal prenatal blood test results could indicate hidden maternal cancers

byNIH/Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentCredit: Josh Willink from PexelsResearchers at the National Institutes of Health (NIH) found previously undet

Abnormal prenatal blood test results could indicate hidden maternal cancers

byNIH/Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentCredit: Josh Willink from PexelsResearchers at the National Institutes of Health (NIH) found previously undet
Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi

Could a pill replace gene therapy for sickle cell disease? Research uncovers potential path to small-molecule drug

by Nancy Fliesler,Children's Hospital BostonNew work suggests ways to target the BCL11A protein with drugs, enabling patients with sickle cell disease to produce non-sickling fetal hemoglobi
Oncologist discusses treating liver cancer

Oncologist discusses treating liver cancer

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainLiver cancer rates have more than tripled in the U.S. since 1980 and continue to rise. More than 41,000 people will be diagnosed with liver

Oncologist discusses treating liver cancer

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainLiver cancer rates have more than tripled in the U.S. since 1980 and continue to rise. More than 41,000 people will be diagnosed with liver
How breast cancer cells survive in bone marrow after remission

How breast cancer cells survive in bone marrow after remission

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI170953A study from researchers at the University of Michigan and the Unive

How breast cancer cells survive in bone marrow after remission

byUniversity of MichiganGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI170953A study from researchers at the University of Michigan and the Unive
Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

byUniversity of TokyoCancer cell during cell division. Credit: National Institutes of HealthTreatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addi

Adding polyvinyl alcohol to a boron-containing drug leads to strong antitumor activity in head and neck cancers

byUniversity of TokyoCancer cell during cell division. Credit: National Institutes of HealthTreatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addi
Neurocognitive battery feasible in 3-year-olds during leukemia treatment

Neurocognitive battery feasible in 3-year-olds during leukemia treatment

by Elana GotkineA brief neurocognitive battery is feasible for use in 3-year-olds during acute lymphoblastic leukemia treatment, according to a studypublishedonline Dec. 9 inPediatri

Neurocognitive battery feasible in 3-year-olds during leukemia treatment

by Elana GotkineA brief neurocognitive battery is feasible for use in 3-year-olds during acute lymphoblastic leukemia treatment, according to a studypublishedonline Dec. 9 inPediatri
Machine learning uncovers three osteosarcoma subtypes for targeted treatment

Machine learning uncovers three osteosarcoma subtypes for targeted treatment

byUniversity of East AngliaLatent process decomposition model optimization, subtype assignment and clinical outcome. Credit:Briefings in Bioinformatics(2024). DOI: 10.1093/bib/bbae66

Machine learning uncovers three osteosarcoma subtypes for targeted treatment

byUniversity of East AngliaLatent process decomposition model optimization, subtype assignment and clinical outcome. Credit:Briefings in Bioinformatics(2024). DOI: 10.1093/bib/bbae66
Cancer risk declines in old age: New research helps explain why

Cancer risk declines in old age: New research helps explain why

by Ian Demsky,Memorial Sloan Kettering Cancer CenterAged AT2 cells exhibit reduced cell-intrinsic potential for regeneration and tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s415

Cancer risk declines in old age: New research helps explain why

by Ian Demsky,Memorial Sloan Kettering Cancer CenterAged AT2 cells exhibit reduced cell-intrinsic potential for regeneration and tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s415
Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

byTampere UniversityOn the left is a tissue sample from the prostate stained with hematoxylin and eosin. Hematoxylin stains the nuclei blue or purple because it binds to DNA, and eosin stains th

Immunosuppression study helps understand why some prostate cancer treatments do not work as expected

byTampere UniversityOn the left is a tissue sample from the prostate stained with hematoxylin and eosin. Hematoxylin stains the nuclei blue or purple because it binds to DNA, and eosin stains th