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Hematology&Oncology
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Researchers identify new target to counteract muscle wasting in pancreatic cancer

Researchers identify new target to counteract muscle wasting in pancreatic cancer

by Laurie Fickman,University of HoustonSynopsis. Credit:EMBO Molecular Medicine(2025). DOI: 10.1038/s44321-025-00337-wResearchers at the University of Houston are pushing the boundaries of biomedical

Researchers identify new target to counteract muscle wasting in pancreatic cancer

by Laurie Fickman,University of HoustonSynopsis. Credit:EMBO Molecular Medicine(2025). DOI: 10.1038/s44321-025-00337-wResearchers at the University of Houston are pushing the boundaries of biomedical
uPAR-targeted CAR T cells shrank solid tumors and cleared metastases in mice

uPAR-targeted CAR T cells shrank solid tumors and cleared metastases in mice

byMemorial Sloan Kettering Cancer CenterCredit:Cell(2026). DOI: 10.1016/j.cell.2026.03.002Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers li

uPAR-targeted CAR T cells shrank solid tumors and cleared metastases in mice

byMemorial Sloan Kettering Cancer CenterCredit:Cell(2026). DOI: 10.1016/j.cell.2026.03.002Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers li
Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer

Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer

by Associação Advanced Breast Cancer Global AllianceWhole body lean mass, which is an indicator of muscle mass, increased in the exercise group, while it decreased in the control group. Credit: Anne M

Study shows supervised exercise improves strength, physical performance in patients with advanced breast cancer

by Associação Advanced Breast Cancer Global AllianceWhole body lean mass, which is an indicator of muscle mass, increased in the exercise group, while it decreased in the control group. Credit: Anne M
Pesticides and cancer: Study reveals the biological mechanisms behind an environmental health risk

Pesticides and cancer: Study reveals the biological mechanisms behind an environmental health risk

byPasteur InstituteCredit: Mark Stebnicki from PexelsA new study, published inNature Health, reveals a strong link between exposure to agricultural pesticides in the environment and the risk of develo

Pesticides and cancer: Study reveals the biological mechanisms behind an environmental health risk

byPasteur InstituteCredit: Mark Stebnicki from PexelsA new study, published inNature Health, reveals a strong link between exposure to agricultural pesticides in the environment and the risk of develo
Can marijuana cause lung cancer?

Can marijuana cause lung cancer?

byUniversity of Southern CaliforniaCredit: Erik Mclean from PexelsAs more states legalize marijuana, many people might be wondering if that means it is safe to use. While smoking tobacco is a known an

Can marijuana cause lung cancer?

byUniversity of Southern CaliforniaCredit: Erik Mclean from PexelsAs more states legalize marijuana, many people might be wondering if that means it is safe to use. While smoking tobacco is a known an
AI model can predict chemotherapy benefit in breast cancer

AI model can predict chemotherapy benefit in breast cancer

byTechnion - Israel Institute of TechnologyStudy cohorts, deep learning system architecture, and performance evaluation on TAILORx-Test. Credit:The Lancet Oncology(2026). DOI: 10.1016/s1470-2045(25)00

AI model can predict chemotherapy benefit in breast cancer

byTechnion - Israel Institute of TechnologyStudy cohorts, deep learning system architecture, and performance evaluation on TAILORx-Test. Credit:The Lancet Oncology(2026). DOI: 10.1016/s1470-2045(25)00
Rearranging tumor cell structures—new approach could treat cancer

Rearranging tumor cell structures—new approach could treat cancer

by Tim Tedeschi,University of CincinnatiBiomedical research typically follows a familiar path: developing treatments that block, enhance or mutate certain signaling pathways, genes or proteins to chan

Rearranging tumor cell structures—new approach could treat cancer

by Tim Tedeschi,University of CincinnatiBiomedical research typically follows a familiar path: developing treatments that block, enhance or mutate certain signaling pathways, genes or proteins to chan
Why some cancer therapies don't work for all patients: A tumor backup survival pathway

Why some cancer therapies don't work for all patients: A tumor backup survival pathway

by Anne Trafton,Massachusetts Institute of TechnologyMany of the targeted tumors turn on a backup survival pathway that helps them keep growing when tyrosine kinase—pictured here as strands—is turned

Why some cancer therapies don't work for all patients: A tumor backup survival pathway

by Anne Trafton,Massachusetts Institute of TechnologyMany of the targeted tumors turn on a backup survival pathway that helps them keep growing when tyrosine kinase—pictured here as strands—is turned
A new immunotherapy target? How SRC-3 in Tregs may reshape solid-tumor treatment

A new immunotherapy target? How SRC-3 in Tregs may reshape solid-tumor treatment

by Ana María Rodríguez,Baylor College of MedicineThe loss of SRC-3 in Treg leads to immune suppression of glioblastoma in mice: (A) Experimental design for the orthotopic injection of glioblastoma cel

A new immunotherapy target? How SRC-3 in Tregs may reshape solid-tumor treatment

by Ana María Rodríguez,Baylor College of MedicineThe loss of SRC-3 in Treg leads to immune suppression of glioblastoma in mice: (A) Experimental design for the orthotopic injection of glioblastoma cel
Genetic variants involved in rapid immune response linked to earlier breast cancer onset in BRCA1 carriers

Genetic variants involved in rapid immune response linked to earlier breast cancer onset in BRCA1 carriers

byBritish Medical JournalCredit: CC0 Public DomainDamaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers o

Genetic variants involved in rapid immune response linked to earlier breast cancer onset in BRCA1 carriers

byBritish Medical JournalCredit: CC0 Public DomainDamaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers o
PSMA therapy delays hormone therapy in prostate cancer, clinical trial finds

PSMA therapy delays hormone therapy in prostate cancer, clinical trial finds

byRadboud UniversityNuclear medicine physician James Nagarajah from Radboudumc in the clinics. Credit: RadboudumcWhere previous research showed that PSMA therapy for prostate cancer can prolong the li

PSMA therapy delays hormone therapy in prostate cancer, clinical trial finds

byRadboud UniversityNuclear medicine physician James Nagarajah from Radboudumc in the clinics. Credit: RadboudumcWhere previous research showed that PSMA therapy for prostate cancer can prolong the li
New analytical method reveals how drug combinations act in leukemia

New analytical method reveals how drug combinations act in leukemia

byTampere UniversityCoPISA workflow and possible states for target discovery in combinatorial therapy. Credit:Nature Communications(2026). DOI: 10.1038/s41467-026-70394-3Acute myeloid leukemia (AML) r

New analytical method reveals how drug combinations act in leukemia

byTampere UniversityCoPISA workflow and possible states for target discovery in combinatorial therapy. Credit:Nature Communications(2026). DOI: 10.1038/s41467-026-70394-3Acute myeloid leukemia (AML) r