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Hematology&Oncology
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Menopausal status influences long-term benefit from anti-hormonal treatment, study shows

Menopausal status influences long-term benefit from anti-hormonal treatment, study shows

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainToday, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low

Menopausal status influences long-term benefit from anti-hormonal treatment, study shows

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainToday, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low
Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatmentsby Nik Papageorgiou,Ecole Polytechnique Federale de LausanneLymphomoid spiral. Credit: Albert Santamaria-MartinezScientists at EP

Advanced cancer models could help personalize lymphoma treatments

Advanced cancer models could help personalize lymphoma treatmentsby Nik Papageorgiou,Ecole Polytechnique Federale de LausanneLymphomoid spiral. Credit: Albert Santamaria-MartinezScientists at EP
Researchers discover 'crosstalk' mechanism in two key breast cancer molecules

Researchers discover 'crosstalk' mechanism in two key breast cancer molecules

byUniversity of LiverpoolIntegrin αVβ6recruits HER2 and a trafficking regulatory subnetwork comprising RAB5/RAB7A/GDI2 in HER2+ breast cancer cells. Credit:Science Advances(202

Researchers discover 'crosstalk' mechanism in two key breast cancer molecules

byUniversity of LiverpoolIntegrin αVβ6recruits HER2 and a trafficking regulatory subnetwork comprising RAB5/RAB7A/GDI2 in HER2+ breast cancer cells. Credit:Science Advances(202
DNA secreted by tumor cell extracellular vesicles prompts anti-metastatic immune response

DNA secreted by tumor cell extracellular vesicles prompts anti-metastatic immune response

byWeill Cornell Medical CollegeCredit: CC0 Public DomainSpecially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the live

DNA secreted by tumor cell extracellular vesicles prompts anti-metastatic immune response

byWeill Cornell Medical CollegeCredit: CC0 Public DomainSpecially packaged DNA secreted by tumor cells can trigger an immune response that inhibits the metastatic spread of the tumor to the live
Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

byThe Mount Sinai HospitalLurbinectedin augments the anti-tumor immune response of PD-L1 blockade in immunocompetent SCLC models. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.x

Study reveals immune-modulatory mechanism of lurbinectedin in small-cell lung cancer

byThe Mount Sinai HospitalLurbinectedin augments the anti-tumor immune response of PD-L1 blockade in immunocompetent SCLC models. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.x
Detroit cancer center unveils new device for treating liver cancer at home

Detroit cancer center unveils new device for treating liver cancer at home

by Julia CardiCredit: Unsplash/CC0 Public DomainA new device is now available for treating advanced liver cancer at home using electromagnetic waves, the Barbara Ann Karmanos Cancer Institute announce

Detroit cancer center unveils new device for treating liver cancer at home

by Julia CardiCredit: Unsplash/CC0 Public DomainA new device is now available for treating advanced liver cancer at home using electromagnetic waves, the Barbara Ann Karmanos Cancer Institute announce
Recommendations to increase access to whole genome sequencing for children with cancer

Recommendations to increase access to whole genome sequencing for children with cancer

byWellcome Trust Sanger InstituteCredit:BMC Medical Education(2024). DOI: 10.1186/s12909-024-06219-yExperts have published a series of recommendations for improving equity of access

Recommendations to increase access to whole genome sequencing for children with cancer

byWellcome Trust Sanger InstituteCredit:BMC Medical Education(2024). DOI: 10.1186/s12909-024-06219-yExperts have published a series of recommendations for improving equity of access
Overcoming glioblastoma resistance to chemotherapy

Overcoming glioblastoma resistance to chemotherapy

byInstitute for Basic ScienceThe "onion model" illustrates how the one-by-one inactivation of the DNA repair pathways brings about changes in TMZ-induced mutational signatures. Every &

Overcoming glioblastoma resistance to chemotherapy

byInstitute for Basic ScienceThe "onion model" illustrates how the one-by-one inactivation of the DNA repair pathways brings about changes in TMZ-induced mutational signatures. Every &
Enzyme identified as new therapeutic target for 'cold' tumors

Enzyme identified as new therapeutic target for 'cold' tumors

by Rebecca Dzombak,University of MichiganCredit: Pixabay/CC0 Public DomainA study from the University of Michigan Health Rogel Cancer Center may have—at last—cracked the cold case of immunothera

Enzyme identified as new therapeutic target for 'cold' tumors

by Rebecca Dzombak,University of MichiganCredit: Pixabay/CC0 Public DomainA study from the University of Michigan Health Rogel Cancer Center may have—at last—cracked the cold case of immunothera
Fibroblastic reticula cells can organize T cells in the fight against lung cancer

Fibroblastic reticula cells can organize T cells in the fight against lung cancer

by Justin Jackson , Medical XpressGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.10.042Institute of Immunobiology-led research has made a significant breakthrough in under

Fibroblastic reticula cells can organize T cells in the fight against lung cancer

by Justin Jackson , Medical XpressGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.10.042Institute of Immunobiology-led research has made a significant breakthrough in under