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Medical research
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How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also
Researchers discover one million new components of the human genome

Researchers discover one million new components of the human genome

by Anika Hazra,University of TorontoCredit: CC0 Public DomainResearchers at the University of Toronto's Donnelly Center for Cellular and Biomolecular Research have found nearly one million n

Researchers discover one million new components of the human genome

by Anika Hazra,University of TorontoCredit: CC0 Public DomainResearchers at the University of Toronto's Donnelly Center for Cellular and Biomolecular Research have found nearly one million n
New tool improves the search for genes that cause diseases

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch
Common human gene mutations linked to a range of health conditions

Common human gene mutations linked to a range of health conditions

byUniversity of GlasgowPCA plots of principal components calculated from Affymetrix genotype data from the 10,179 participants that had UK Biobank PC1 > 100 and PC2 > 0. (a) Participants w

Common human gene mutations linked to a range of health conditions

byUniversity of GlasgowPCA plots of principal components calculated from Affymetrix genotype data from the 10,179 participants that had UK Biobank PC1 > 100 and PC2 > 0. (a) Participants w
Experimental pain med could give patients new option to opioids

Experimental pain med could give patients new option to opioids

by Ernie MundellThe first new kind of pain medication in over two decades could be on the horizon for patients, with promising results announced Tuesday from a company trial.For now, the drug from Ver

Experimental pain med could give patients new option to opioids

by Ernie MundellThe first new kind of pain medication in over two decades could be on the horizon for patients, with promising results announced Tuesday from a company trial.For now, the drug from Ver
Drug candidate granted FDA orphan drug status for pancreatic cancer

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug
Crack vaccine research on rats could help babies of mothers who use cocaine—and reduce addiction

Crack vaccine research on rats could help babies of mothers who use cocaine—and reduce addiction

by Frederico Garcia,The ConversationScintigraphy shows that many more cocaine molecules reached the brain of pregnant rats that received a placebo than those that received the vaccine. Credit: V

Crack vaccine research on rats could help babies of mothers who use cocaine—and reduce addiction

by Frederico Garcia,The ConversationScintigraphy shows that many more cocaine molecules reached the brain of pregnant rats that received a placebo than those that received the vaccine. Credit: V
New study aims to define the progeria phenome

New study aims to define the progeria phenome

by Impact Journals LLCProgeroid syndrome overview. Credit: 2024 Worm et al.Progeroid disorders are a heterogenous group of rare and complex hereditary syndromes presenting with pleiotropic phenotypes

New study aims to define the progeria phenome

by Impact Journals LLCProgeroid syndrome overview. Credit: 2024 Worm et al.Progeroid disorders are a heterogenous group of rare and complex hereditary syndromes presenting with pleiotropic phenotypes
New genome editing tools unlock possibilities for precision medicine

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a
Gene editing offers hope for people with hereditary disorder

Gene editing offers hope for people with hereditary disorder

byUniversity of AucklandCredit: Pixabay/CC0 Public DomainA group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing ther

Gene editing offers hope for people with hereditary disorder

byUniversity of AucklandCredit: Pixabay/CC0 Public DomainA group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing ther