HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-

Updated on: March 14,2024 11

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-

Updated on:March 14,2024 11

How does HIV get into the cell's center to kickstart infection?

JANUARY 24, 2024 Editors' notesbyUniversity of New South WalesIntact HIV-1 CLPs penetrate Nup98 condensates via FG-binding pocket. Credit:Nature(2024). DOI: 10.1038/s41586-023-06

Updated on: March 14,2024 11

How does HIV get into the cell's center to kickstart infection?

JANUARY 24, 2024 Editors' notesbyUniversity of New South WalesIntact HIV-1 CLPs penetrate Nup98 condensates via FG-binding pocket. Credit:Nature(2024). DOI: 10.1038/s41586-023-06

Updated on:March 14,2024 11

CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

DECEMBER 14, 2023 Editors' notesby C. Michael White,The ConversationCredit: Pixabay/CC0 Public DomainPrescription drugs and vaccines revolutionized health care, dramatically decreasing death

Updated on: March 14,2024 22

CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

DECEMBER 14, 2023 Editors' notesby C. Michael White,The ConversationCredit: Pixabay/CC0 Public DomainPrescription drugs and vaccines revolutionized health care, dramatically decreasing death

Updated on:March 14,2024 22

COPD and the effect of low-dose cadmium, a highly toxic metal, on airway epithelial cells

FEBRUARY 2, 2024 Editors' notesby Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainCigarette smoke exposure is associated with the development and severity of

Updated on: March 14,2024 12

COPD and the effect of low-dose cadmium, a highly toxic metal, on airway epithelial cells

FEBRUARY 2, 2024 Editors' notesby Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainCigarette smoke exposure is associated with the development and severity of

Updated on:March 14,2024 12

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L

Updated on: March 14,2024 5

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L

Updated on:March 14,2024 5

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir

Updated on: March 14,2024 5

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir

Updated on:March 14,2024 5

New insights on kidney disease in African Americans could lead to therapies

by Sarah Avery,Duke UniversityCredit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI172262In a finding that could help reduce the racial disparity in kidney disease, Duke H

Updated on: March 14,2024 3

New insights on kidney disease in African Americans could lead to therapies

by Sarah Avery,Duke UniversityCredit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI172262In a finding that could help reduce the racial disparity in kidney disease, Duke H

Updated on:March 14,2024 3

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever

Updated on: March 14,2024 12

Study with over 11,000 individuals of African descent finds genetic variants linked to glaucoma

byCell PressDiscovery of known and previously undescribed loci from the discovery mega-analysis of African ancestry individuals. Credit: Cell/Verma et al.Glaucoma is the leading cause of irrever

Updated on:March 14,2024 12

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Updated on: March 14,2024 16

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Updated on:March 14,2024 16

Large-scale study explores link between smoking and DNA changes across six racial and ethnic groups

by Zara Abrams,Keck School of Medicine of USCCredit: CC0 Public DomainSmoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-rel

Updated on: March 14,2024 15

Large-scale study explores link between smoking and DNA changes across six racial and ethnic groups

by Zara Abrams,Keck School of Medicine of USCCredit: CC0 Public DomainSmoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-rel

Updated on:March 14,2024 15

Danish study could pave the way for better diagnosis of rare genetic diseases

byAarhus UniversityGraphical abstract. Credit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2023.12.024There are over 7,000 different rare genetic diseases, and o

Updated on: March 14,2024 5

Danish study could pave the way for better diagnosis of rare genetic diseases

byAarhus UniversityGraphical abstract. Credit:The American Journal of Human Genetics(2024). DOI: 10.1016/j.ajhg.2023.12.024There are over 7,000 different rare genetic diseases, and o

Updated on:March 14,2024 5

Predicting neurodevelopmental disease in children from parents' traits

by Sam Sholtis,Pennsylvania State UniversityNeurodevelopmental and psychiatric disorders, and the genes that can lead to them, vary in a population (left, brighter red colors represent more seve

Updated on: March 14,2024 7

Predicting neurodevelopmental disease in children from parents' traits

by Sam Sholtis,Pennsylvania State UniversityNeurodevelopmental and psychiatric disorders, and the genes that can lead to them, vary in a population (left, brighter red colors represent more seve

Updated on:March 14,2024 7