Researchers find mitochondrial DNA damage triggers spread of Parkinson's disease-like pathology

byUniversity of CopenhagenComplex I respiratory chain subunits are altered in PD patients and PD models(Ifnb-/-/Ifnar1-/-) due to mtDNA damages.AEnrichment plot of KEGG-OXPHOS

Updated on: March 13,2024 6

Researchers find mitochondrial DNA damage triggers spread of Parkinson's disease-like pathology

byUniversity of CopenhagenComplex I respiratory chain subunits are altered in PD patients and PD models(Ifnb-/-/Ifnar1-/-) due to mtDNA damages.AEnrichment plot of KEGG-OXPHOS

Updated on:March 13,2024 6

Study shows why women are at greater risk of autoimmune disease

byStanford University Medical CenterCredit: Pixabay/CC0 Public DomainSomewhere between 24 and 50 million Americans have an autoimmune disease, a condition in which the immune system attacks our

Updated on: March 13,2024 13

Study shows why women are at greater risk of autoimmune disease

byStanford University Medical CenterCredit: Pixabay/CC0 Public DomainSomewhere between 24 and 50 million Americans have an autoimmune disease, a condition in which the immune system attacks our

Updated on:March 13,2024 13

Researchers create a new tool to rapidly diagnose genetic mutations

byUniversity of CalgaryGraphical abstract. Credit:Cell Reports Methods(2024). DOI: 10.1016/j.crmeth.2024.100698Dr. Pierre Billon, Ph.D., was frustrated with the time it took to get g

Updated on: March 13,2024 8

Researchers create a new tool to rapidly diagnose genetic mutations

byUniversity of CalgaryGraphical abstract. Credit:Cell Reports Methods(2024). DOI: 10.1016/j.crmeth.2024.100698Dr. Pierre Billon, Ph.D., was frustrated with the time it took to get g

Updated on:March 13,2024 8

Researchers discover a new role for a protein that helps form memories

by Marya Barlow,Virginia Tech(From left) Research scientist Kayla Farrell and Associate Professor Tim Jarome in the School of Animal Sciences are part of a Virginia Tech research team that disco

Updated on: March 13,2024 8

Researchers discover a new role for a protein that helps form memories

by Marya Barlow,Virginia Tech(From left) Research scientist Kayla Farrell and Associate Professor Tim Jarome in the School of Animal Sciences are part of a Virginia Tech research team that disco

Updated on:March 13,2024 8

Genetics may influence the body's response to low oxygen, study finds

byUniversity of PittsburghImmunofluorescent staining for the lncRNA fragment in a diseased pulmonary vessel from a patient with pulmonary arterial hypertension. Credit: Thomas BerteroUniversity

Updated on: March 13,2024 11

Genetics may influence the body's response to low oxygen, study finds

byUniversity of PittsburghImmunofluorescent staining for the lncRNA fragment in a diseased pulmonary vessel from a patient with pulmonary arterial hypertension. Credit: Thomas BerteroUniversity

Updated on:March 13,2024 11

New research finds that exposure to odorant-based HDAC inhibitors could delay neurological disease onset

byUniversity of California - RiversideRemote exposure to HDACi volatile alters gene expression in an invertebrate and vertebrate. Credit:eLife(2024). DOI: 10.7554/eLife.86823.3Imagin

Updated on: March 13,2024 13

New research finds that exposure to odorant-based HDAC inhibitors could delay neurological disease onset

byUniversity of California - RiversideRemote exposure to HDACi volatile alters gene expression in an invertebrate and vertebrate. Credit:eLife(2024). DOI: 10.7554/eLife.86823.3Imagin

Updated on:March 13,2024 13

Study finds ancestry-driven disparities in pathogenic variation

by Molly Chiu,Baylor College of MedicinePathogenic variants by ancestry. 1a shows the rates of pathogenic variation, broken down by predicted genetic ancestry groups. 1b shows the breakdown of p

Updated on: March 13,2024 13

Study finds ancestry-driven disparities in pathogenic variation

by Molly Chiu,Baylor College of MedicinePathogenic variants by ancestry. 1a shows the rates of pathogenic variation, broken down by predicted genetic ancestry groups. 1b shows the breakdown of p

Updated on:March 13,2024 13

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani

Updated on: March 13,2024 7

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani

Updated on:March 13,2024 7

Study shows how genes in retina are regulated during development

byNational Institutes of HealthThis image metaphorically captures the cell differentiation process during retinal organoid development. Loose yarn representing uncompacted DNA is wound by a croc

Updated on: March 13,2024 8

Study shows how genes in retina are regulated during development

byNational Institutes of HealthThis image metaphorically captures the cell differentiation process during retinal organoid development. Loose yarn representing uncompacted DNA is wound by a croc

Updated on:March 13,2024 8

Study shows tendency for infection and bacterial flora explain caries

byUmea UniversityCredit:eBioMedicine(2024). DOI: 10.1016/j.ebiom.2024.105001Researchers at Umeå University have for the first time been able to show that individual variation in susc

Updated on: March 13,2024 13

Study shows tendency for infection and bacterial flora explain caries

byUmea UniversityCredit:eBioMedicine(2024). DOI: 10.1016/j.ebiom.2024.105001Researchers at Umeå University have for the first time been able to show that individual variation in susc

Updated on:March 13,2024 13

Interactions between flu subtypes found to predict epidemic severity more than virus evolution

by Emily PackerEmily Packer,eLifeAntigenic and genetic evolution of seasonal influenza A(H3N2) viruses, 1997—2019. A-B.Temporal phylogenies of hemagglutinin (H3) and neuraminidase (N2) gene segm

Updated on: March 13,2024 12

Interactions between flu subtypes found to predict epidemic severity more than virus evolution

by Emily PackerEmily Packer,eLifeAntigenic and genetic evolution of seasonal influenza A(H3N2) viruses, 1997—2019. A-B.Temporal phylogenies of hemagglutinin (H3) and neuraminidase (N2) gene segm

Updated on:March 13,2024 12

Genetic testing pinpoints cardiovascular risk in patients with aortic disorders

by Vincent Jacobbi,Mayo ClinicCredit: Pixabay/CC0 Public DomainA new Mayo Clinic systematicreview, published in theJournal of Vascular Surgeryhas shed light on genetically inhe

Updated on: March 13,2024 4

Genetic testing pinpoints cardiovascular risk in patients with aortic disorders

by Vincent Jacobbi,Mayo ClinicCredit: Pixabay/CC0 Public DomainA new Mayo Clinic systematicreview, published in theJournal of Vascular Surgeryhas shed light on genetically inhe

Updated on:March 13,2024 4