A small molecule blocks aversive memory formation, providing a potential treatment target for depression

byCity University of Hong KongThe YM022-treated mice (diagram A, second from right) spent significantly more time in the social interaction zone (framed with a green line) than the control group

Updated on: January 10,2024 15

A small molecule blocks aversive memory formation, providing a potential treatment target for depression

byCity University of Hong KongThe YM022-treated mice (diagram A, second from right) spent significantly more time in the social interaction zone (framed with a green line) than the control group

Updated on:January 10,2024 15

Rodents may see moving objects in a way similar to primates, visual cortex study suggests

byInternational School of Advanced Studies (SISSA)To accurately perceive the direction of moving objects, rats could exploit a small but very useful cluster of visual neurons, which seem to work

Updated on: January 10,2024 12

Rodents may see moving objects in a way similar to primates, visual cortex study suggests

byInternational School of Advanced Studies (SISSA)To accurately perceive the direction of moving objects, rats could exploit a small but very useful cluster of visual neurons, which seem to work

Updated on:January 10,2024 12

Research challenges traditional theory of mechanisms of cocaine self-administration

by Bill Bangert,University of CincinnatiThe cumulative record of injections (A), active lever presses (B), and the calculated levels of cocaine at the time of each event (C) during a representat

Updated on: January 10,2024 7

Research challenges traditional theory of mechanisms of cocaine self-administration

by Bill Bangert,University of CincinnatiThe cumulative record of injections (A), active lever presses (B), and the calculated levels of cocaine at the time of each event (C) during a representat

Updated on:January 10,2024 7

Study provides molecular blueprint of spinal circuits governing locomotor speed

byKarolinska InstitutetSingle-cell RNAseq of GFP+neurons in isl1a:GFP and chx10:GFP transgenic lines. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01479-1Researche

Updated on: January 10,2024 7

Study provides molecular blueprint of spinal circuits governing locomotor speed

byKarolinska InstitutetSingle-cell RNAseq of GFP+neurons in isl1a:GFP and chx10:GFP transgenic lines. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01479-1Researche

Updated on:January 10,2024 7

Cellular 'waste product' rejuvenates cancer-fighting immune cells

byUT Southwestern Medical CenterUT Southwestern Simmons Cancer Center found that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that figh

Updated on: January 10,2024 10

Cellular 'waste product' rejuvenates cancer-fighting immune cells

byUT Southwestern Medical CenterUT Southwestern Simmons Cancer Center found that lactate, a metabolic byproduct produced by cells during strenuous exercise, can rejuvenate immune cells that figh

Updated on:January 10,2024 10

New study sheds light on how our brains perceive—or fail to perceive—what we see

byAllen Institute for Brain ScienceCredit: Magoi from PexelsA newstudyinNature Neuroscienceon 'visual masking' sheds light on how we 'unsee' things and po

Updated on: January 10,2024 20

New study sheds light on how our brains perceive—or fail to perceive—what we see

byAllen Institute for Brain ScienceCredit: Magoi from PexelsA newstudyinNature Neuroscienceon 'visual masking' sheds light on how we 'unsee' things and po

Updated on:January 10,2024 20

Researchers identify molecular link between gut bacteria and excitatory brain signaling in C. elegans

by Jim Fessenden, UMass Chan Medical SchoolB12produced by gut bacteria suppresses the hyperactive behavior of unc-2(gof) mutants. Credit:Nature Cell Biology(2024). DOI: 10.1038/s4155

Updated on: January 09,2024 12

Researchers identify molecular link between gut bacteria and excitatory brain signaling in C. elegans

by Jim Fessenden, UMass Chan Medical SchoolB12produced by gut bacteria suppresses the hyperactive behavior of unc-2(gof) mutants. Credit:Nature Cell Biology(2024). DOI: 10.1038/s4155

Updated on:January 09,2024 12

Researchers identify and manipulate neural circuits for risk/reward decision-making in primates

by Spyros Goulas, Institute for the Advanced Study of Human Biology (ASHBI)Bananas represent the reward and the crocodile represents the risk. The blue path is a low risk-low return decision, while th

Updated on: January 09,2024 19

Researchers identify and manipulate neural circuits for risk/reward decision-making in primates

by Spyros Goulas, Institute for the Advanced Study of Human Biology (ASHBI)Bananas represent the reward and the crocodile represents the risk. The blue path is a low risk-low return decision, while th

Updated on:January 09,2024 19

Lifespan increases in mice when specific brain cells are activated, study finds

by Julia Evangelou Strait,Washington University School of MedicineWith age, the researchers found that the protein Ppp1r17 tends to leave the nucleus of the neurons, and when that happens, the n

Updated on: January 09,2024 13

Lifespan increases in mice when specific brain cells are activated, study finds

by Julia Evangelou Strait,Washington University School of MedicineWith age, the researchers found that the protein Ppp1r17 tends to leave the nucleus of the neurons, and when that happens, the n

Updated on:January 09,2024 13

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02

Updated on: January 09,2024 9

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02

Updated on:January 09,2024 9

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Updated on: January 09,2024 9

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Updated on:January 09,2024 9

How memories are formed in the brain: A new role for the internal compass

byUniversitaet TübingenSocial interactions dynamically modulated the gain of the HD representation. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-023-01506-1Since their disco

Updated on: January 09,2024 9

How memories are formed in the brain: A new role for the internal compass

byUniversitaet TübingenSocial interactions dynamically modulated the gain of the HD representation. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-023-01506-1Since their disco

Updated on:January 09,2024 9