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FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)
AI-based analysis identifies two plant extracts with potential as GLP-1 agonist weight loss pills

AI-based analysis identifies two plant extracts with potential as GLP-1 agonist weight loss pills

by European Association for the Study of ObesityCredit: AI-generated imageTwo plant compounds with potential as GLP-1 agonist weight loss pills have been identified in an AI (artificial intelligence)-

AI-based analysis identifies two plant extracts with potential as GLP-1 agonist weight loss pills

by European Association for the Study of ObesityCredit: AI-generated imageTwo plant compounds with potential as GLP-1 agonist weight loss pills have been identified in an AI (artificial intelligence)-
West Virginia city once battered by opioid overdoses confronts 'fourth wave'

West Virginia city once battered by opioid overdoses confronts 'fourth wave'

by Taylor Sisk, KFF Health NewsCredit: CC0 Public DomainFrom 2006 through 2014, more than 81 million painkiller pills were shipped to this city and surrounding rural Cabell County.The arrival of presc

West Virginia city once battered by opioid overdoses confronts 'fourth wave'

by Taylor Sisk, KFF Health NewsCredit: CC0 Public DomainFrom 2006 through 2014, more than 81 million painkiller pills were shipped to this city and surrounding rural Cabell County.The arrival of presc
New research identifies promising drug combination for multiple myeloma treatment

New research identifies promising drug combination for multiple myeloma treatment

byRoyal College of Surgeons in IrelandCredit: Unsplash/CC0 Public DomainNew research from the Royal College of Surgeons in Ireland has found that venetoclax, a medication currently approved for

New research identifies promising drug combination for multiple myeloma treatment

byRoyal College of Surgeons in IrelandCredit: Unsplash/CC0 Public DomainNew research from the Royal College of Surgeons in Ireland has found that venetoclax, a medication currently approved for
Mifepristone access is coming before the US Supreme Court. How safe is this abortion pill?

Mifepristone access is coming before the US Supreme Court. How safe is this abortion pill?

by LAURA UNGAR and MATTHEW PERRONEBoxes of the drug mifepristone sit on a shelf at the West Alabama Women's Center in Tuscaloosa, Ala., on March 16, 2022. On Tuesday, March 26, 2024, the U.S. Supr

Mifepristone access is coming before the US Supreme Court. How safe is this abortion pill?

by LAURA UNGAR and MATTHEW PERRONEBoxes of the drug mifepristone sit on a shelf at the West Alabama Women's Center in Tuscaloosa, Ala., on March 16, 2022. On Tuesday, March 26, 2024, the U.S. Supr
Q&A: A digital twin that allows tailored medication

Q&A: A digital twin that allows tailored medication

by Anna Björklund,Karolinska InstitutetOverview of the scDrugPrio workflow. Single-cell RNA-sequencing (scRNA-seq) data from either individuals or groups of patients are preprocessed by undergoi

Q&A: A digital twin that allows tailored medication

by Anna Björklund,Karolinska InstitutetOverview of the scDrugPrio workflow. Single-cell RNA-sequencing (scRNA-seq) data from either individuals or groups of patients are preprocessed by undergoi
There's only one syphilis medication for pregnant people and the supply is running out

There's only one syphilis medication for pregnant people and the supply is running out

by Alena Kuzub,Northeastern UniversityThe pharmaceutical company Pfizer is the sole manufacturer of penicillin G benzathine, the only medicine that safely treats syphilis in pregnant people. Cre

There's only one syphilis medication for pregnant people and the supply is running out

by Alena Kuzub,Northeastern UniversityThe pharmaceutical company Pfizer is the sole manufacturer of penicillin G benzathine, the only medicine that safely treats syphilis in pregnant people. Cre
Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

byWileyChest images of completely vaccinated sick moderate patients with SARS-CoV-2. Panel A-D: Four cases of vaccinated patients with pneumonia, no previous antibiotic use before hospital admis

Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

byWileyChest images of completely vaccinated sick moderate patients with SARS-CoV-2. Panel A-D: Four cases of vaccinated patients with pneumonia, no previous antibiotic use before hospital admis
Metformin during pregnancy impacts offspring brain development, finds study

Metformin during pregnancy impacts offspring brain development, finds study

by Deutsches Zentrum fuer Diabetesforschung DZDMaternal HFD intake during lactation leads to excessive maternal weight gain and hyperglycemia at weaning which is not affected by metformin treatment. C

Metformin during pregnancy impacts offspring brain development, finds study

by Deutsches Zentrum fuer Diabetesforschung DZDMaternal HFD intake during lactation leads to excessive maternal weight gain and hyperglycemia at weaning which is not affected by metformin treatment. C
New data show pembrolizumab improves breast cancer outcomes regardless of age or menopausal status

New data show pembrolizumab improves breast cancer outcomes regardless of age or menopausal status

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainNew data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug pembrolizuma

New data show pembrolizumab improves breast cancer outcomes regardless of age or menopausal status

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainNew data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug pembrolizuma
Autophagy-tethering compounds may open new directions in targeted drug discovery

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting
Study eases concern at antipsychotics use in pregnancy

Study eases concern at antipsychotics use in pregnancy

byUniversity of New South WalesCrude and propensity score-weighted cumulative incidence (with 95% confidence intervals) for composite neurodevelopmental outcome from age 3–19 years in children o

Study eases concern at antipsychotics use in pregnancy

byUniversity of New South WalesCrude and propensity score-weighted cumulative incidence (with 95% confidence intervals) for composite neurodevelopmental outcome from age 3–19 years in children o