New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a

Updated on: April 23,2024 0

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a

Updated on:April 23,2024 0

New study aims to define the progeria phenome

by Impact Journals LLCProgeroid syndrome overview. Credit: 2024 Worm et al.Progeroid disorders are a heterogenous group of rare and complex hereditary syndromes presenting with pleiotropic phenotypes

Updated on: April 23,2024 0

New study aims to define the progeria phenome

by Impact Journals LLCProgeroid syndrome overview. Credit: 2024 Worm et al.Progeroid disorders are a heterogenous group of rare and complex hereditary syndromes presenting with pleiotropic phenotypes

Updated on:April 23,2024 0

Crack vaccine research on rats could help babies of mothers who use cocaine—and reduce addiction

by Frederico Garcia,The ConversationScintigraphy shows that many more cocaine molecules reached the brain of pregnant rats that received a placebo than those that received the vaccine. Credit: V

Updated on: April 23,2024 17

Crack vaccine research on rats could help babies of mothers who use cocaine—and reduce addiction

by Frederico Garcia,The ConversationScintigraphy shows that many more cocaine molecules reached the brain of pregnant rats that received a placebo than those that received the vaccine. Credit: V

Updated on:April 23,2024 17

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Updated on: April 23,2024 14

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Updated on:April 23,2024 14

Experimental pain med could give patients new option to opioids

by Ernie MundellThe first new kind of pain medication in over two decades could be on the horizon for patients, with promising results announced Tuesday from a company trial.For now, the drug from Ver

Updated on: April 24,2024 15

Experimental pain med could give patients new option to opioids

by Ernie MundellThe first new kind of pain medication in over two decades could be on the horizon for patients, with promising results announced Tuesday from a company trial.For now, the drug from Ver

Updated on:April 24,2024 15

Common human gene mutations linked to a range of health conditions

byUniversity of GlasgowPCA plots of principal components calculated from Affymetrix genotype data from the 10,179 participants that had UK Biobank PC1 > 100 and PC2 > 0. (a) Participants w

Updated on: April 26,2024 0

Common human gene mutations linked to a range of health conditions

byUniversity of GlasgowPCA plots of principal components calculated from Affymetrix genotype data from the 10,179 participants that had UK Biobank PC1 > 100 and PC2 > 0. (a) Participants w

Updated on:April 26,2024 0

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch

Updated on: April 26,2024 0

New tool improves the search for genes that cause diseases

byUniversity of ChicagoDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Ch

Updated on:April 26,2024 0

Researchers discover one million new components of the human genome

by Anika Hazra,University of TorontoCredit: CC0 Public DomainResearchers at the University of Toronto's Donnelly Center for Cellular and Biomolecular Research have found nearly one million n

Updated on: April 26,2024 0

Researchers discover one million new components of the human genome

by Anika Hazra,University of TorontoCredit: CC0 Public DomainResearchers at the University of Toronto's Donnelly Center for Cellular and Biomolecular Research have found nearly one million n

Updated on:April 26,2024 0

Integration of proteomics, transcriptomics and AI in identification of aging markers

Updated on: April 27,2024 0

Integration of proteomics, transcriptomics and AI in identification of aging markers

Updated on:April 27,2024 0

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also

Updated on: April 27,2024 0

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also

Updated on:April 27,2024 0

Exploring ethical and legal ramifications of growing brain organoids from human fetal brain tissue

byHiroshima UniversityCredit: Unsplash/CC0 Public DomainBrain organoids, though often referred to as "mini brains," are not truly human brains. But the concerns over these lab-grown br

Updated on: April 27,2024 0

Exploring ethical and legal ramifications of growing brain organoids from human fetal brain tissue

byHiroshima UniversityCredit: Unsplash/CC0 Public DomainBrain organoids, though often referred to as "mini brains," are not truly human brains. But the concerns over these lab-grown br

Updated on:April 27,2024 0

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Updated on: April 27,2024 0

Research team discovers new way to generate human cartilage

byUniversity of MontanaA graph of gene expression patterns of organoids created in a University of Montana lab transitioning to become cells that form human cartilage. It's overlaid on a pic

Updated on:April 27,2024 0