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Medical research
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Light-activated muscle grafts show promise in aiding muscle recovery post-trauma

Light-activated muscle grafts show promise in aiding muscle recovery post-trauma

byMassachusetts Institute of TechnologyRitu Raman (center), the d’Arbeloff Career Development Assistant Professor of Mechanical Engineering, speaks with students in her lab. Credit: Tony Pulsone

Light-activated muscle grafts show promise in aiding muscle recovery post-trauma

byMassachusetts Institute of TechnologyRitu Raman (center), the d’Arbeloff Career Development Assistant Professor of Mechanical Engineering, speaks with students in her lab. Credit: Tony Pulsone
New software tool decodes cytokine 'language' of immune cells

New software tool decodes cytokine 'language' of immune cells

by Julie Parry,Yale School of MedicineOverview of the CINEMA-OT framework. a, scRNA-seq count data is first decomposed into confounder variation and treatment-associated variation using ICA. Cel

New software tool decodes cytokine 'language' of immune cells

by Julie Parry,Yale School of MedicineOverview of the CINEMA-OT framework. a, scRNA-seq count data is first decomposed into confounder variation and treatment-associated variation using ICA. Cel
A breath of fresh air keeps drug-producing cells alive longer

A breath of fresh air keeps drug-producing cells alive longer

byNorthwestern UniversityA side-by-side comparison of cells supported by the oxygenation device (left) and cells without the device support (right). Living cells are shown in green; dead cells a

A breath of fresh air keeps drug-producing cells alive longer

byNorthwestern UniversityA side-by-side comparison of cells supported by the oxygenation device (left) and cells without the device support (right). Living cells are shown in green; dead cells a
'Lab on a chip' genetic test device can identify viruses within three minutes with top-level accuracy

'Lab on a chip' genetic test device can identify viruses within three minutes with top-level accuracy

byUniversity of BathDr Despina Moschou with LoCKAmp replaceable lab on chip printed circuit board. Credit: University of BathA virus diagnosis device that gives lab-quality results within just t

'Lab on a chip' genetic test device can identify viruses within three minutes with top-level accuracy

byUniversity of BathDr Despina Moschou with LoCKAmp replaceable lab on chip printed circuit board. Credit: University of BathA virus diagnosis device that gives lab-quality results within just t
Proof of concept of new material for long lasting relief from dry mouth conditions

Proof of concept of new material for long lasting relief from dry mouth conditions

byUniversity of LeedsLactoferrin which is a protein found in milk—colored dark blue—forms the mesh-like architecture of the hydrated microgel, partially coated by a hydrogel made by a polysaccha

Proof of concept of new material for long lasting relief from dry mouth conditions

byUniversity of LeedsLactoferrin which is a protein found in milk—colored dark blue—forms the mesh-like architecture of the hydrated microgel, partially coated by a hydrogel made by a polysaccha
Special polymer for microfluidic chips could reduce need for animal testing in medical research

Special polymer for microfluidic chips could reduce need for animal testing in medical research

by Elizaveta Vereshchagina and Linda Sønstevold,Norwegian University of Science and TechnologySINTEF researchers Linda Sønstevold (right) and Elizaveta Vereshchagina have achieved promising resu

Special polymer for microfluidic chips could reduce need for animal testing in medical research

by Elizaveta Vereshchagina and Linda Sønstevold,Norwegian University of Science and TechnologySINTEF researchers Linda Sønstevold (right) and Elizaveta Vereshchagina have achieved promising resu
Genetically engineered cell therapies with mRNA lipid nanoparticles for transferrable platelets

Genetically engineered cell therapies with mRNA lipid nanoparticles for transferrable platelets

by Thamarasee Jeewandara , Phys.orgPlatelets transfected with mRNA using LNP can express exogenous protein. (A) Schematic describing the transfection of platelets using mRNA-LNP. (B) NanoLuc expressio

Genetically engineered cell therapies with mRNA lipid nanoparticles for transferrable platelets

by Thamarasee Jeewandara , Phys.orgPlatelets transfected with mRNA using LNP can express exogenous protein. (A) Schematic describing the transfection of platelets using mRNA-LNP. (B) NanoLuc expressio
Dual-targeting CAR NK cells can prevent cell dysfunction and tumor escape

Dual-targeting CAR NK cells can prevent cell dysfunction and tumor escape

byUniversity of Texas M. D. Anderson Cancer CenterKaty Rezvani, M.D., Ph.D., working in her laboratory. Credit: MD Anderson Cancer CenterResearchers at The University of Texas MD Anderson Cancer

Dual-targeting CAR NK cells can prevent cell dysfunction and tumor escape

byUniversity of Texas M. D. Anderson Cancer CenterKaty Rezvani, M.D., Ph.D., working in her laboratory. Credit: MD Anderson Cancer CenterResearchers at The University of Texas MD Anderson Cancer
How bispecific antibodies could bring new hope to patients with lung cancer

How bispecific antibodies could bring new hope to patients with lung cancer

by Cactus CommunicationsMOAs of bsAbs in the treatment of lung cancer. (A) One arm of a bsAb binds to TAA/TSA, and the other to a T-cell surface receptor, and this bridging mechanism redirects cytotox

How bispecific antibodies could bring new hope to patients with lung cancer

by Cactus CommunicationsMOAs of bsAbs in the treatment of lung cancer. (A) One arm of a bsAb binds to TAA/TSA, and the other to a T-cell surface receptor, and this bridging mechanism redirects cytotox
Dual acting drug delivers blood cancer a lethal 'one-two' punch in mice

Dual acting drug delivers blood cancer a lethal 'one-two' punch in mice

byMonash UniversityCredit: Monash UniversityMelbourne researchers have designed a single drug that delivers a lethal "one-two" punch to several types of blood cancer in preclinical stu

Dual acting drug delivers blood cancer a lethal 'one-two' punch in mice

byMonash UniversityCredit: Monash UniversityMelbourne researchers have designed a single drug that delivers a lethal "one-two" punch to several types of blood cancer in preclinical stu
A potent antibiotic has emerged in the battle against deadly, drug-resistant superbugs

A potent antibiotic has emerged in the battle against deadly, drug-resistant superbugs

Acinetobacter baumannii, seen under a scanning electron microscope, is a gram-negative bacterium responsible for thousands of hospitalizations and hundreds of deaths in the U.S. each year. An experime

A potent antibiotic has emerged in the battle against deadly, drug-resistant superbugs

Acinetobacter baumannii, seen under a scanning electron microscope, is a gram-negative bacterium responsible for thousands of hospitalizations and hundreds of deaths in the U.S. each year. An experime
Advances and challenges in gene therapy for rare diseases

Advances and challenges in gene therapy for rare diseases

by Kathryn Ryan,Mary Ann Liebert, IncThis stylistic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). The chromosome is X-shaped because it is di

Advances and challenges in gene therapy for rare diseases

by Kathryn Ryan,Mary Ann Liebert, IncThis stylistic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). The chromosome is X-shaped because it is di