Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Updated on: January 09,2024 9

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Updated on:January 09,2024 9

How memories are formed in the brain: A new role for the internal compass

byUniversitaet TübingenSocial interactions dynamically modulated the gain of the HD representation. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-023-01506-1Since their disco

Updated on: January 09,2024 9

How memories are formed in the brain: A new role for the internal compass

byUniversitaet TübingenSocial interactions dynamically modulated the gain of the HD representation. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-023-01506-1Since their disco

Updated on:January 09,2024 9

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Updated on: January 09,2024 10

Variants in synaptic scaffolding protein PPFIA3 discovered to cause new syndromic neurodevelopmental disorder

byTexas Children's HospitalCredit: Pixabay/CC0 Public DomainAn international collaborative study has recently discovered that variants in the PPFIA3 gene cause a previously unknown syndromic

Updated on:January 09,2024 10

Comparing human and mouse Purkinje cells to better understand human brain complexity

by Bob Yirka , Medical XpressHuman and mouse PC morphological properties. a Morphological reconstructions of a mouse and a human PC obtained from fluorescent confocal images of postmortem fixated brai

Updated on: January 09,2024 10

Comparing human and mouse Purkinje cells to better understand human brain complexity

by Bob Yirka , Medical XpressHuman and mouse PC morphological properties. a Morphological reconstructions of a mouse and a human PC obtained from fluorescent confocal images of postmortem fixated brai

Updated on:January 09,2024 10

How a suction cup delivers medications to the bloodstream

by Christoph Elhardt,ETH ZurichThe suction cup contains active ingredients and can be pressed onto the lining of the check with two fingers. Credit: Luo Z et al. 2023, editedResearchers at ETH Z

Updated on: January 07,2024 13

How a suction cup delivers medications to the bloodstream

by Christoph Elhardt,ETH ZurichThe suction cup contains active ingredients and can be pressed onto the lining of the check with two fingers. Credit: Luo Z et al. 2023, editedResearchers at ETH Z

Updated on:January 07,2024 13

Scientists develop tunable organic active neural probe enabling near-sensor signal processing

byPohang University of Science and Technology(a) Structure and functional mechanism of an implantable brain signal amplification sensor created using inkjet printing technology. (b) Magnified li

Updated on: January 07,2024 12

Scientists develop tunable organic active neural probe enabling near-sensor signal processing

byPohang University of Science and Technology(a) Structure and functional mechanism of an implantable brain signal amplification sensor created using inkjet printing technology. (b) Magnified li

Updated on:January 07,2024 12

Study in mice shows blocking abnormal stem cell signal during aging lessens related bone loss

byNYU Langone HealthCredit: CC0 Public DomainA cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.The study, led by re

Updated on: January 07,2024 20

Study in mice shows blocking abnormal stem cell signal during aging lessens related bone loss

byNYU Langone HealthCredit: CC0 Public DomainA cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.The study, led by re

Updated on:January 07,2024 20

New sensor technology measures THC levels in saliva

by Kim Horner,University of Texas at DallasOpen Circuit Potential of the sensing platform in PBS. Credit:The Analyst(2023). DOI: 10.1039/D3AN00522DUniversity of Texas at Dallas resea

Updated on: January 07,2024 13

New sensor technology measures THC levels in saliva

by Kim Horner,University of Texas at DallasOpen Circuit Potential of the sensing platform in PBS. Credit:The Analyst(2023). DOI: 10.1039/D3AN00522DUniversity of Texas at Dallas resea

Updated on:January 07,2024 13

New test for sepsis could save lives in emergency departments, study suggests

by Aaron Wagner,Pennsylvania State UniversityTwo-way sensitivity analysis of the sensitivity and specificity of procalcitonin. Base case values are indicated in red. ISI = IntelliSep Index. Cred

Updated on: January 07,2024 8

New test for sepsis could save lives in emergency departments, study suggests

by Aaron Wagner,Pennsylvania State UniversityTwo-way sensitivity analysis of the sensitivity and specificity of procalcitonin. Base case values are indicated in red. ISI = IntelliSep Index. Cred

Updated on:January 07,2024 8

Bioinspired flexible network scaffolds for soft tissue regeneration

by Thamarasee Jeewandara , Medical XpressInverse design concept and fabrication techniques of flexible network scaffolds for soft tissue regeneration. Schematic illustration of electrospun conduit sca

Updated on: January 06,2024 8

Bioinspired flexible network scaffolds for soft tissue regeneration

by Thamarasee Jeewandara , Medical XpressInverse design concept and fabrication techniques of flexible network scaffolds for soft tissue regeneration. Schematic illustration of electrospun conduit sca

Updated on:January 06,2024 8

Researchers develop mixture of compounds to help preserve organs before transplantation

byWileyIndividual CPA toxicity assay (A) and identification of best performing external CPAs cocktail capable of retaining larvae viability after 22 min of storage at −10°C when immersed in CPAs

Updated on: January 06,2024 15

Researchers develop mixture of compounds to help preserve organs before transplantation

byWileyIndividual CPA toxicity assay (A) and identification of best performing external CPAs cocktail capable of retaining larvae viability after 22 min of storage at −10°C when immersed in CPAs

Updated on:January 06,2024 15

New frontier in biomedical engineering: Protein coacervates engineered into adhesive for unprecedented skin repair speed

by Engineering(a) Schematic diagram of ECM composition. Elastin and growth factor are important components of the ECM. (b) Construction and expression of the protein. (c) Preparation of the EED adhesi

Updated on: January 06,2024 15

New frontier in biomedical engineering: Protein coacervates engineered into adhesive for unprecedented skin repair speed

by Engineering(a) Schematic diagram of ECM composition. Elastin and growth factor are important components of the ECM. (b) Construction and expression of the protein. (c) Preparation of the EED adhesi

Updated on:January 06,2024 15