Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit

Updated on: August 26,2024 0

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit

Updated on:August 26,2024 0

Researchers report encouraging first evidence of effective new gene therapy to treat multiple sulfatase deficiency

byChildren's Hospital of PhiladelphiaCredit:Molecular Therapy(2024). DOI: 10.1016/j.ymthe.2024.08.015Researchers from Children's Hospital of Philadelphia (CHOP) have tested a

Updated on: September 14,2024 0

Researchers report encouraging first evidence of effective new gene therapy to treat multiple sulfatase deficiency

byChildren's Hospital of PhiladelphiaCredit:Molecular Therapy(2024). DOI: 10.1016/j.ymthe.2024.08.015Researchers from Children's Hospital of Philadelphia (CHOP) have tested a

Updated on:September 14,2024 0

Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus in genome

by Petra Sandow,University Hospital BonnManhattan plot of the metaEURanalysis. The −log10association P values (vertical axis) for all variants of the metaEURanalysis against th

Updated on: March 14,2024 13

Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus in genome

by Petra Sandow,University Hospital BonnManhattan plot of the metaEURanalysis. The −log10association P values (vertical axis) for all variants of the metaEURanalysis against th

Updated on:March 14,2024 13

Researchers uncover genetic factors for severe Lassa fever

by Allessandra DiCorato,Broad Institute of MIT and HarvardScanning electron image of the Lassa virus budding off a cell. Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Marylan

Updated on: March 13,2024 6

Researchers uncover genetic factors for severe Lassa fever

by Allessandra DiCorato,Broad Institute of MIT and HarvardScanning electron image of the Lassa virus budding off a cell. Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Marylan

Updated on:March 13,2024 6

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

Updated on: March 25,2024 6

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

Updated on:March 25,2024 6

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease

Updated on: March 30,2024 3

Drugs of the future will be easier and faster to make, thanks to mRNA—after researchers work out a few remaining kinks

JANUARY 5, 2024by Li Li,The ConversationThis is a computer graphic of an RNA molecule. Credit: Richard Feldmann/WikipediaVaccines have been reliably and affordably protecting people from disease

Updated on:March 30,2024 3

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir

Updated on: March 14,2024 5

New insight into gene uncovers its link to incurable birth defect

byWalter and Eliza Hall Institute of Medical Researchimage shows neurons and their connections to each other in red and yellow, and the cell's DNA in blue. WEHI researchers have, for the fir

Updated on:March 14,2024 5

Common human gene mutations linked to a range of health conditions

byUniversity of GlasgowPCA plots of principal components calculated from Affymetrix genotype data from the 10,179 participants that had UK Biobank PC1 > 100 and PC2 > 0. (a) Participants w

Updated on: April 26,2024 0

Common human gene mutations linked to a range of health conditions

byUniversity of GlasgowPCA plots of principal components calculated from Affymetrix genotype data from the 10,179 participants that had UK Biobank PC1 > 100 and PC2 > 0. (a) Participants w

Updated on:April 26,2024 0

Could artificial intelligence help or hurt medical research articles?

FEBRUARY 6, 2024byIndiana University School of MedicineOverview of experimental study design employed to examine the utility of using ChatGPT to write scientific review articles about the inters

Updated on: March 25,2024 9

Could artificial intelligence help or hurt medical research articles?

FEBRUARY 6, 2024byIndiana University School of MedicineOverview of experimental study design employed to examine the utility of using ChatGPT to write scientific review articles about the inters

Updated on:March 25,2024 9

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Updated on: April 06,2024 0

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Updated on:April 06,2024 0

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of

Updated on: March 30,2024 0

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of

Updated on:March 30,2024 0

Research suggests chronic pain is different for males and females

JANUARY 24, 2024by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainA University of Alberta research team has uncovered differences in the way male and female mice develo

Updated on: March 27,2024 6

Research suggests chronic pain is different for males and females

JANUARY 24, 2024by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainA University of Alberta research team has uncovered differences in the way male and female mice develo

Updated on:March 27,2024 6