First clinical trial of vosoritide for children with hypochondroplasia shows increased growth

byChildren's National HospitalStanding height SDS. Credit:eClinicalMedicine(2024). DOI: 10.1016/j.eclinm.2024.102591Vosoritide's first global Phase II study showed an average

Updated on: April 28,2024 0

First clinical trial of vosoritide for children with hypochondroplasia shows increased growth

byChildren's National HospitalStanding height SDS. Credit:eClinicalMedicine(2024). DOI: 10.1016/j.eclinm.2024.102591Vosoritide's first global Phase II study showed an average

Updated on:April 28,2024 0

Organs-on-chips provide insights into molecular mechanisms of disease, facilitate design of newer treatment strategies

by Xia & He Publishing Inc.An illustration of organ-on-chip simulating the biological microenvironment. Credit:Journal of Exploratory Research in Pharmacology(2024). DOI: 10.14218/JERP

Updated on: July 23,2024 0

Organs-on-chips provide insights into molecular mechanisms of disease, facilitate design of newer treatment strategies

by Xia & He Publishing Inc.An illustration of organ-on-chip simulating the biological microenvironment. Credit:Journal of Exploratory Research in Pharmacology(2024). DOI: 10.14218/JERP

Updated on:July 23,2024 0

Mouse study finds birth coincides with rapid changes in gene activity

FEBRUARY 15, 2024byUniversity of Washington School of MedicineTranscriptional heterogeneity in the posterior embryo during early somitogenesis.a, Re-embedded 3D UMAP of 121,118 cells from

Updated on: March 15,2024 5

Mouse study finds birth coincides with rapid changes in gene activity

FEBRUARY 15, 2024byUniversity of Washington School of MedicineTranscriptional heterogeneity in the posterior embryo during early somitogenesis.a, Re-embedded 3D UMAP of 121,118 cells from

Updated on:March 15,2024 5

New trial highlights incremental progress towards a cure for HIV-1

FEBRUARY 13, 2024byUniversity of North Carolina School of MedicineLymphocyte with HIV cluster. Credit: Unsplash/CC0 Public DomainAntiretroviral therapies (ART) stop HIV replication in its tracks

Updated on: March 25,2024 11

New trial highlights incremental progress towards a cure for HIV-1

FEBRUARY 13, 2024byUniversity of North Carolina School of MedicineLymphocyte with HIV cluster. Credit: Unsplash/CC0 Public DomainAntiretroviral therapies (ART) stop HIV replication in its tracks

Updated on:March 25,2024 11

Mature 'lab grown' neurons hold promise for neurodegenerative disease

by Northwestern UniversityFluorescent images of human neurons (stained with red, green and blue) growing on coatings with fast-moving molecules (left) or conventional laminin (right) for 72 hours

Updated on: February 05,2024 11

Mature 'lab grown' neurons hold promise for neurodegenerative disease

by Northwestern UniversityFluorescent images of human neurons (stained with red, green and blue) growing on coatings with fast-moving molecules (left) or conventional laminin (right) for 72 hours

Updated on:February 05,2024 11

Scientists say outdated diabetes drug still has something to offer

byUniversity of California - San DiegoThis micrograph shows a single macrophage, which is a type of cell in the immune system. In obesity-related inflammation, large numbers of these cells infil

Updated on: April 28,2024 0

Scientists say outdated diabetes drug still has something to offer

byUniversity of California - San DiegoThis micrograph shows a single macrophage, which is a type of cell in the immune system. In obesity-related inflammation, large numbers of these cells infil

Updated on:April 28,2024 0

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02

Updated on: January 09,2024 9

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02

Updated on:January 09,2024 9

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a

Updated on: April 23,2024 0

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a

Updated on:April 23,2024 0

New study sheds light on the rate, nature and transmission of mitochondrial DNA mutations in humans

by deCODE geneticsStructure of the human mitochondrial genome. Credit: Wikipedia/CC BY-SA 3.0A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on t

Updated on: June 15,2024 5

New study sheds light on the rate, nature and transmission of mitochondrial DNA mutations in humans

by deCODE geneticsStructure of the human mitochondrial genome. Credit: Wikipedia/CC BY-SA 3.0A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on t

Updated on:June 15,2024 5

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on: March 28,2024 1

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on:March 28,2024 1

New implant and app enable patients to monitor bladder function

by Northwestern UniversityThe device wirelessly and continuously transmits data to a smartphone app, so users (and their physicians) can monitor bladder filling and function in real time. Credit:

Updated on: March 27,2024 0

New implant and app enable patients to monitor bladder function

by Northwestern UniversityThe device wirelessly and continuously transmits data to a smartphone app, so users (and their physicians) can monitor bladder filling and function in real time. Credit:

Updated on:March 27,2024 0

Understanding molecular drivers of lymphedema

by Olivia Dimmer,Northwestern UniversityCredit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI176577Northwestern Medicine scientists have uncovered molecular mechanisms und

Updated on: July 23,2024 0

Understanding molecular drivers of lymphedema

by Olivia Dimmer,Northwestern UniversityCredit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI176577Northwestern Medicine scientists have uncovered molecular mechanisms und

Updated on:July 23,2024 0