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Medical research
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Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules
Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of

Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

by Steven Lee,University of Texas Health Science Center at San AntonioCredit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.02.033Magnesium is a mineral critical to a wide range of
Study of palliative care demonstrates scalable strategy to increase support for seriously ill patients in hospital

Study of palliative care demonstrates scalable strategy to increase support for seriously ill patients in hospital

JANUARY 16, 2024byPerelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainOrdering a palliative care consultation by "default"—via an automatic o

Study of palliative care demonstrates scalable strategy to increase support for seriously ill patients in hospital

JANUARY 16, 2024byPerelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainOrdering a palliative care consultation by "default"—via an automatic o
Study finds cilostazol is well tolerated but doesn't prevent cognitive decline

Study finds cilostazol is well tolerated but doesn't prevent cognitive decline

DECEMBER 6, 2023by National Cerebral and Cardiovascular CenterCredit: JAMA Network Open/ National Cerebral and Cardiovascular CenterA recent study demonstrated the safety of cilostazol in patients wit

Study finds cilostazol is well tolerated but doesn't prevent cognitive decline

DECEMBER 6, 2023by National Cerebral and Cardiovascular CenterCredit: JAMA Network Open/ National Cerebral and Cardiovascular CenterA recent study demonstrated the safety of cilostazol in patients wit
Testing found recalled medicine can have a deadly bacterial contamination

Testing found recalled medicine can have a deadly bacterial contamination

by David J. Neal, Miami HeraldCredit: Pixabay/CC0 Public DomainA drug used to treat a form of pneumonia has been recalled after testing found it might be as deadly as the infection it's supposed t

Testing found recalled medicine can have a deadly bacterial contamination

by David J. Neal, Miami HeraldCredit: Pixabay/CC0 Public DomainA drug used to treat a form of pneumonia has been recalled after testing found it might be as deadly as the infection it's supposed t
Researchers identify new biomarker in quality of blood donations

Researchers identify new biomarker in quality of blood donations

by Kelsea Pieters,CU Anschutz Medical CampusCredit: CC0 Public DomainA collaborative cohort of researchers, led by University of Colorado Anschutz Medical Campus professor Angelo D'Alessandr

Researchers identify new biomarker in quality of blood donations

by Kelsea Pieters,CU Anschutz Medical CampusCredit: CC0 Public DomainA collaborative cohort of researchers, led by University of Colorado Anschutz Medical Campus professor Angelo D'Alessandr
Researchers develop model to assess biology of human placental barrier

Researchers develop model to assess biology of human placental barrier

by Tokyo Medical and Dental UniversityPlacental organoids generated from human placental stem cells (left), a front view of the placental barrier model (center), and a side view of the barrier mo

Researchers develop model to assess biology of human placental barrier

by Tokyo Medical and Dental UniversityPlacental organoids generated from human placental stem cells (left), a front view of the placental barrier model (center), and a side view of the barrier mo
Preoperative GLP-1 agonist use does not increase aspiration

Preoperative GLP-1 agonist use does not increase aspiration

by Elana GotkinePreoperative glucagon-like peptide-1 (GLP-1) agonist use does not increase the risk for aspiration or subsequent pneumonia in patients undergoing various surgical procedures, according

Preoperative GLP-1 agonist use does not increase aspiration

by Elana GotkinePreoperative glucagon-like peptide-1 (GLP-1) agonist use does not increase the risk for aspiration or subsequent pneumonia in patients undergoing various surgical procedures, according
World-first human trial finds arthritis drug can suppress progression of type 1 diabetes

World-first human trial finds arthritis drug can suppress progression of type 1 diabetes

DECEMBER 6, 2023bySt Vincent's Institute of Medical ResearchCredit: CC0 Public DomainResearchers at St Vincent's Institute of Medical Research (SVI) in Melbourne have shown that a common

World-first human trial finds arthritis drug can suppress progression of type 1 diabetes

DECEMBER 6, 2023bySt Vincent's Institute of Medical ResearchCredit: CC0 Public DomainResearchers at St Vincent's Institute of Medical Research (SVI) in Melbourne have shown that a common
FGF-2 found to promote periodontal healing in an osteoporosis model rat

FGF-2 found to promote periodontal healing in an osteoporosis model rat

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Pixabay/CC0 Public DomainA study investigating the effects of local application of fibroblast growth factor (FGF-2) on p

FGF-2 found to promote periodontal healing in an osteoporosis model rat

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Pixabay/CC0 Public DomainA study investigating the effects of local application of fibroblast growth factor (FGF-2) on p
Familial Alzheimer's disease transferred via bone marrow transplant in mice

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr

Familial Alzheimer's disease transferred via bone marrow transplant in mice

byCell PressA painting representing Alzheimer's transmissibility as reported in thisStem Cell Reportsstudy. Credit: Chaahat SinghFamilial Alzheimer's disease can be transferr