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Medical research
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Transdifferentiation with RNA sequencing aids diagnosis of genetic disorders

Transdifferentiation with RNA sequencing aids diagnosis of genetic disorders

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine have tested the feasibility of using human cell transdifferentiation with RNA

Transdifferentiation with RNA sequencing aids diagnosis of genetic disorders

by Molly Chiu,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainResearchers at Baylor College of Medicine have tested the feasibility of using human cell transdifferentiation with RNA
Prolonged use of certain hormone drugs linked to increased brain tumor risk

Prolonged use of certain hormone drugs linked to increased brain tumor risk

by British Medical JournalMeningiomas are graded by microscopic appearance, rate of growth and tendency to invade other tissues. Credit: National Cancer InstituteProlonged use of certain progesto

Prolonged use of certain hormone drugs linked to increased brain tumor risk

by British Medical JournalMeningiomas are graded by microscopic appearance, rate of growth and tendency to invade other tissues. Credit: National Cancer InstituteProlonged use of certain progesto
Patients regain much weight after stopping new obesity drug: Study

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On

Patients regain much weight after stopping new obesity drug: Study

This is an image of a weight scale. Credit: CDC/Debora CartagenaA new generation of obesity drugs often delivers dramatic weight loss, but many patients wonder what happens when they stop treatment.On
Scientists improve the equation in FDA guidance predicting drug interactions

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und
Plozasiran reduces triglyceride levels by 74% at 24 weeks

Plozasiran reduces triglyceride levels by 74% at 24 weeks

byAmerican College of CardiologyCredit: CC0 Public DomainIn patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran red

Plozasiran reduces triglyceride levels by 74% at 24 weeks

byAmerican College of CardiologyCredit: CC0 Public DomainIn patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran red
New vaccine against fatal tropical disease and potential bioterror weapon demonstrates efficacy in animal studies

New vaccine against fatal tropical disease and potential bioterror weapon demonstrates efficacy in animal studies

by Marcus Horwitz,University of California, Los AngelesBurkholderia pseudomallei infecting a human cell. The bacteria (red) are polymerizing actin (green). Credit: Christopher T. FrenchIn a mous

New vaccine against fatal tropical disease and potential bioterror weapon demonstrates efficacy in animal studies

by Marcus Horwitz,University of California, Los AngelesBurkholderia pseudomallei infecting a human cell. The bacteria (red) are polymerizing actin (green). Credit: Christopher T. FrenchIn a mous
Researchers race to develop Paxlovid replacement

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor
Researchers shed light on the molecular causes of different functions of opioid receptors

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti
Scientists develop tunable organic active neural probe enabling near-sensor signal processing

Scientists develop tunable organic active neural probe enabling near-sensor signal processing

byPohang University of Science and Technology(a) Structure and functional mechanism of an implantable brain signal amplification sensor created using inkjet printing technology. (b) Magnified li

Scientists develop tunable organic active neural probe enabling near-sensor signal processing

byPohang University of Science and Technology(a) Structure and functional mechanism of an implantable brain signal amplification sensor created using inkjet printing technology. (b) Magnified li
Understanding what causes trastuzumab's cardiotoxicity

Understanding what causes trastuzumab's cardiotoxicity

byMary Ann Liebert, IncCredit: Pixabay/CC0 Public DomainA new meta-analysispublishedinOMICS: A Journal of Integrative Biologyhelps shed light on how changes in mitochondr

Understanding what causes trastuzumab's cardiotoxicity

byMary Ann Liebert, IncCredit: Pixabay/CC0 Public DomainA new meta-analysispublishedinOMICS: A Journal of Integrative Biologyhelps shed light on how changes in mitochondr
FDA's plan to ban hair relaxer chemical called too little, too late

FDA's plan to ban hair relaxer chemical called too little, too late

FEBRUARY 13, 2024 Editors' notesby Ronnie Cohen, KFF Health NewsCredit: Pixabay/CC0 Public DomainIn April, a dozen years after a federal agency classified formaldehyde a human carcinogen, the Food

FDA's plan to ban hair relaxer chemical called too little, too late

FEBRUARY 13, 2024 Editors' notesby Ronnie Cohen, KFF Health NewsCredit: Pixabay/CC0 Public DomainIn April, a dozen years after a federal agency classified formaldehyde a human carcinogen, the Food
ADHD drug shortages are affecting patients in the UK—here's why they're happening

ADHD drug shortages are affecting patients in the UK—here's why they're happening

by Liz Breen and Jonathan Silcock,The ConversationCredit: Pixabay/CC0 Public DomainMillions of people in the UK who take drugs for attention deficit hyperactivity disorder (ADHD) are facing diff

ADHD drug shortages are affecting patients in the UK—here's why they're happening

by Liz Breen and Jonathan Silcock,The ConversationCredit: Pixabay/CC0 Public DomainMillions of people in the UK who take drugs for attention deficit hyperactivity disorder (ADHD) are facing diff