New study aims to define the progeria phenome

by Impact Journals LLCProgeroid syndrome overview. Credit: 2024 Worm et al.Progeroid disorders are a heterogenous group of rare and complex hereditary syndromes presenting with pleiotropic phenotypes

Updated on: April 23,2024 0

New study aims to define the progeria phenome

by Impact Journals LLCProgeroid syndrome overview. Credit: 2024 Worm et al.Progeroid disorders are a heterogenous group of rare and complex hereditary syndromes presenting with pleiotropic phenotypes

Updated on:April 23,2024 0

How does HIV get into the cell's center to kickstart infection?

JANUARY 24, 2024 Editors' notesbyUniversity of New South WalesIntact HIV-1 CLPs penetrate Nup98 condensates via FG-binding pocket. Credit:Nature(2024). DOI: 10.1038/s41586-023-06

Updated on: March 14,2024 11

How does HIV get into the cell's center to kickstart infection?

JANUARY 24, 2024 Editors' notesbyUniversity of New South WalesIntact HIV-1 CLPs penetrate Nup98 condensates via FG-binding pocket. Credit:Nature(2024). DOI: 10.1038/s41586-023-06

Updated on:March 14,2024 11

Study: Solid organ transplant patients benefit from COVID-19 treatment

byCedars-Sinai Medical CenterTix-Cil dosing and infections during the study period. The frequency and timing of Tix-Cil dosing and SARS-CoV-2 infections occurring in the study cohort is shown in

Updated on: January 26,2024 19

Study: Solid organ transplant patients benefit from COVID-19 treatment

byCedars-Sinai Medical CenterTix-Cil dosing and infections during the study period. The frequency and timing of Tix-Cil dosing and SARS-CoV-2 infections occurring in the study cohort is shown in

Updated on:January 26,2024 19

Study finds moderately elevated fracture risk following use of sedative–hypnotics

byThe University of Hong KongCredit: Unsplash/CC0 Public DomainGlobal consumption data show that there is an increasing trend of sedative–hypnotic prescriptions, especially in more developed aff

Updated on: January 26,2024 20

Study finds moderately elevated fracture risk following use of sedative–hypnotics

byThe University of Hong KongCredit: Unsplash/CC0 Public DomainGlobal consumption data show that there is an increasing trend of sedative–hypnotic prescriptions, especially in more developed aff

Updated on:January 26,2024 20

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

Updated on: May 30,2024 0

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

Updated on:May 30,2024 0

Study finds new treatment makes patients with life-threatening muscle weakness stronger

byAarhus UniversityCredit: Unsplash/CC0 Public DomainFor the thousands of people globally affected by the disease myasthenia gravis (MG), everyday activities become a struggle, and in severe cas

Updated on: March 28,2024 0

Study finds new treatment makes patients with life-threatening muscle weakness stronger

byAarhus UniversityCredit: Unsplash/CC0 Public DomainFor the thousands of people globally affected by the disease myasthenia gravis (MG), everyday activities become a struggle, and in severe cas

Updated on:March 28,2024 0

A non-canonical mechanism for RNA damage compartmentalization and daughter cell protection

Updated on: August 08,2024 0

A non-canonical mechanism for RNA damage compartmentalization and daughter cell protection

Updated on:August 08,2024 0

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Updated on: March 28,2024 0

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Updated on:March 28,2024 0

FDA approves oral Duvyzat for Duchenne muscular dystrophy

by Lori SolomonThe U.S. Food and Drug Administration has approved Duvyzat (givinostat) as an oral medication for the treatment of Duchenne muscular dystrophy (DMD) in patients six years of age and old

Updated on: March 28,2024 0

FDA approves oral Duvyzat for Duchenne muscular dystrophy

by Lori SolomonThe U.S. Food and Drug Administration has approved Duvyzat (givinostat) as an oral medication for the treatment of Duchenne muscular dystrophy (DMD) in patients six years of age and old

Updated on:March 28,2024 0

Oleic acid: A potential therapy for people with a rare genetic condition

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainA mutation in a protein regulating natural killer (NK) cells' function is at the root of immune deficiency in some peo

Updated on: April 27,2024 0

Oleic acid: A potential therapy for people with a rare genetic condition

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainA mutation in a protein regulating natural killer (NK) cells' function is at the root of immune deficiency in some peo

Updated on:April 27,2024 0

Researchers reveal mechanisms of alarmin release at an early stage of immune reaction

byLudwig Maximilian University of MunichSchematic of the experimental design; PBMCs, peripheral blood mononuclear cells. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01656

Updated on: January 27,2024 16

Researchers reveal mechanisms of alarmin release at an early stage of immune reaction

byLudwig Maximilian University of MunichSchematic of the experimental design; PBMCs, peripheral blood mononuclear cells. Credit:Nature Immunology(2023). DOI: 10.1038/s41590-023-01656

Updated on:January 27,2024 16

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02

Updated on: January 09,2024 9

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02

Updated on:January 09,2024 9