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Medical research
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Researchers make mice a more powerful tool to study a wide range of human diseases

Researchers make mice a more powerful tool to study a wide range of human diseases

byJackson LaboratoryThe new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles ce

Researchers make mice a more powerful tool to study a wide range of human diseases

byJackson LaboratoryThe new protocol coaxes mouse stem cells to develop across multiple strains of mice, not just strain 129. This enables researchers to identify which strain best resemebles ce
Deciphering the role of bitter and astringent polyphenols in promoting well-being

Deciphering the role of bitter and astringent polyphenols in promoting well-being

by Shibaura Institute of TechnologyDietary uptake of polyphenols alters the gut microflora and stimulates the secretion of specific hormones that induce cross-talk with the brain via the sensory

Deciphering the role of bitter and astringent polyphenols in promoting well-being

by Shibaura Institute of TechnologyDietary uptake of polyphenols alters the gut microflora and stimulates the secretion of specific hormones that induce cross-talk with the brain via the sensory
Migraine sufferers in England may soon be able to access a preventative drug: Atogepant

Migraine sufferers in England may soon be able to access a preventative drug: Atogepant

by Anna Andreou,The ConversationCredit: Unsplash/CC0 Public DomainA drug that can help prevent migraines could soon be available on the NHS. Atogepant (brand name: Aquipta) was recently recommen

Migraine sufferers in England may soon be able to access a preventative drug: Atogepant

by Anna Andreou,The ConversationCredit: Unsplash/CC0 Public DomainA drug that can help prevent migraines could soon be available on the NHS. Atogepant (brand name: Aquipta) was recently recommen
Cockayne syndrome: New insights into cellular DNA repair mechanism

Cockayne syndrome: New insights into cellular DNA repair mechanism

byLudwig Maximilian University of MunichDPC-seq enables genome-wide mapping of DPC induction and resolution. An overview of the DPC-seq methodology. Cultured cells are treated with 1.75 mM forma

Cockayne syndrome: New insights into cellular DNA repair mechanism

byLudwig Maximilian University of MunichDPC-seq enables genome-wide mapping of DPC induction and resolution. An overview of the DPC-seq methodology. Cultured cells are treated with 1.75 mM forma
Off-label use of a common antibiotic to treat muscular dystrophy

Off-label use of a common antibiotic to treat muscular dystrophy

byOsaka UniversityMechanisms of molecular pathology and erythromycin treatment in myotonic dystrophy type 1 In myotonic dystrophy type 1, aberrant RNA transcribed from the mutant DMPK gene leads

Off-label use of a common antibiotic to treat muscular dystrophy

byOsaka UniversityMechanisms of molecular pathology and erythromycin treatment in myotonic dystrophy type 1 In myotonic dystrophy type 1, aberrant RNA transcribed from the mutant DMPK gene leads
Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c
Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

by St. Jude Children's Research HospitalResearchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness ag

Re-engineered antibiotic shows potential for treatment of drug-resistant bacteria

by St. Jude Children's Research HospitalResearchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness ag
New genome editing tools unlock possibilities for precision medicine

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a
Drug found to extend survival in prostate cancer with genetic mutations

Drug found to extend survival in prostate cancer with genetic mutations

by Melissa Rohman,Northwestern University(A) rPFS for patients with a germline BRCA alteration, (B) rPFS for patients with a somatic BRCA alteration, (C) OS for patients with a germline BRCA alt

Drug found to extend survival in prostate cancer with genetic mutations

by Melissa Rohman,Northwestern University(A) rPFS for patients with a germline BRCA alteration, (B) rPFS for patients with a somatic BRCA alteration, (C) OS for patients with a germline BRCA alt