Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Updated on: April 28,2024 0

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Updated on:April 28,2024 0

Researchers create real-time view of placental development in mice

by Michaela Martinez,Duke UniversityCredit: Duke UniversityPhysicians and biomedical engineers at Duke University have developed a method to visualize the growth of a placenta throughout a mouse

Updated on: March 30,2024 0

Researchers create real-time view of placental development in mice

by Michaela Martinez,Duke UniversityCredit: Duke UniversityPhysicians and biomedical engineers at Duke University have developed a method to visualize the growth of a placenta throughout a mouse

Updated on:March 30,2024 0

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

Updated on: May 30,2024 0

CRISPR-based mapping uncovers 'switches' for immune genes central to health

byGladstone InstitutesTiling CRISPRi screens map gene-specific CREs across the costimulatory locus. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01743-5Healthy T cells are t

Updated on:May 30,2024 0

The dual role of YAP/TAZ in tissue senescence and fibrosis

Updated on: June 05,2024 0

The dual role of YAP/TAZ in tissue senescence and fibrosis

Updated on:June 05,2024 0

Genetic mosaicism more common than thought, study shows

Updated on: May 30,2024 0

Genetic mosaicism more common than thought, study shows

Updated on:May 30,2024 0

Chicken eggs could provide low-cost opportunities for cancer imaging research

JANUARY 4, 2024byKing's College LondonComparison of in ovo and in vivo18F-FDG PET/CT imaging.aRepresentative in ovo18F-FDG PET/CT images 40–60 min p.i.. White arrows

Updated on: March 15,2024 7

Chicken eggs could provide low-cost opportunities for cancer imaging research

JANUARY 4, 2024byKing's College LondonComparison of in ovo and in vivo18F-FDG PET/CT imaging.aRepresentative in ovo18F-FDG PET/CT images 40–60 min p.i.. White arrows

Updated on:March 15,2024 7

Super permeable wearable electronics developed for stable, long-term biosignal monitoring

by Michael Gibb,City University of Hong KongThe permeable wearable electronics developed by the team for long-term biosignal monitoring. Credit: City University of Hong KongSuper wearable electr

Updated on: March 30,2024 0

Super permeable wearable electronics developed for stable, long-term biosignal monitoring

by Michael Gibb,City University of Hong KongThe permeable wearable electronics developed by the team for long-term biosignal monitoring. Credit: City University of Hong KongSuper wearable electr

Updated on:March 30,2024 0

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern

Updated on: March 25,2024 6

How to make mRNA therapeutics safe from the start

FEBRUARY 28, 2024by Cynthia McCormick Hibbert,Northeastern UniversityScientists eager to harness mRNA technology to fight cancer and more need to find ways to test early for safety, Northeastern

Updated on:March 25,2024 6

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat

Updated on: April 06,2024 0

A potential method for interrupting the misfolding of tau protein that underlies neurodegenerative disease

by Sonia Fernandez,University of California - Santa BarbaraInvestigation of the effect of VHH Z70 nanobody on jR2R3 P301L-induced tau fibrillization in cells. Credit:Proceedings of the Nat

Updated on:April 06,2024 0

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on: April 06,2024 0

Enhancing hypoxia-activated prodrug anticancer therapy

by Science China PressOn the top, (a) Chemical structure of TPZP. On the bottom, (b) Schematic diagram of combined therapy. Art by Michael Rothman. Art by Zhaohui Tang. Credit: Science China Pres

Updated on:April 06,2024 0

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on: March 28,2024 1

Researchers design novel drug delivery system that could reverse Alzheimer's disease impact

FEBRUARY 21, 2024byUniversity of North Carolina at Chapel HillChirality inversion mechanisms. Scheme and TEM images (a) of Fmoc-FFFF-PEG2 prepared at RT, or heated to 37 and 40 °C to track the c

Updated on:March 28,2024 1

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

Updated on: March 30,2024 1

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

Updated on:March 30,2024 1